Rhododendric acid A, a new ursane-type PTP1B inhibitor from the endangered plant Rhododendron brachycarpum G. Don

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 19, 2012, Pages 6116-6119

  Choi, Yeon Ho ^a   Zhou, Wei ^a   Oh, Joonseok ^a   Choe, Sanggil ^b   Kim, Dong Woo ^b   Lee, Seung Ho ^a   Na, Minkyun ^c  

^a Yeungnam University   (South Korea)

^b National Forensic Service   (South Korea)

^c Chungnam National University   (South Korea)

Author keywords

Endangered plant; Log P value; Protein tyrosine phosphatase 1B; Rhododendric acid; Rhododendron brachycarpum

Indexed keywords

PLANT EXTRACT; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; RHODODENDRIC ACID A; RHODODENDRON BRACHYCARPUM EXTRACT; TRITERPENOID; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DETERMINATION; DRUG ISOLATION; DRUG POTENCY; DRUG PURIFICATION; DRUG RESEARCH; FEASIBILITY STUDY; FRACTIONATION; IC 50; LIPOPHILICITY; NONHUMAN; PLANT LEAF; RHODODENDRON; RHODODENDRON BRACHYCARPUM;

DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ERICACEAE; MOLECULAR STRUCTURE; PLANT LEAVES; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RECOMBINANT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES;

ERICACEAE; RHODODENDRON BRACHYCARPUM;

EID: 84866420564     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.08.029     Document Type: Article

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