Protein tyrosine phosphatase 1B inhibitory activity of triterpenes isolated from Astilbe koreana

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 12, 2006, Pages 3273-3276

  Na, MinKyun ^a   Cui, Long ^a   Min, Byung Sun ^b   Bae, KiHwan ^c   Yoo, Jae Kuk ^c   Kim, Bo Yeon ^a   Oh, Won Keun ^a   Ahn, Jong Seog ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Catholic University of Daegu   (South Korea)

^c Chungnam National University   (South Korea)

Author keywords

3 ,24 Dihydroxyolean 12 en 27 oic acid; Astilbe koreana; Protein tyrosine phosphatase 1B (PTP1B); Saxifragaceae; Triterpenes

Indexed keywords

3 OXOOLEAN 12 EN 27 OIC ACID; 3ALPHA,24 DIHYDROXYOLEAN 12 EN 27 OIC ACID; 3BETA ACETOXYOLEAN 12 EN 27 OIC ACID; 3BETA HYDROXYOLEAN 12 EN 27 OIC ACID; 3BETA HYDROXYURS 12 EN 27 OIC ACID; 3BETA,6BETA DIHYDROXYOLEAN 12 EN 27 OIC ACID; ASTILBE KOREANA EXTRACT; ASTILBIC ACID; BETA PELTOBOYKINOLIC ACID; CARBOXYL GROUP; HYDROXYL GROUP; METHANOL; METHYL 3BETA HYDROXYOLEAN 12 EN 27 OIC ACID; PLANT EXTRACT; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; TRITERPENE; UNCLASSIFIED DRUG;

ARTICLE; ASTILBE KOREANA; BIOASSAY; DRUG EFFECT; DRUG INHIBITION; DRUG ISOLATION; DRUG SCREENING; IC 50; IN VITRO STUDY; MEDICINAL PLANT; NONHUMAN; RHIZOME; SAXIFRAGACEAE;

ENZYME INHIBITORS; HUMANS; MOLECULAR STRUCTURE; PROTEIN-TYROSINE-PHOSPHATASE; SAXIFRAGACEAE; TRITERPENES;

ASTILBE; SAXIFRAGACEAE;

EID: 33646182208     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.03.036     Document Type: Article

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