Hypoxia is a modifier of SMN2 splicing and disease severity in a severe SMA mouse model

Human Molecular Genetics

Volumn 21, Issue 19, 2012, Pages 4301-4313

  Bebee, Thomas W ^a,b   Dominguez, Catherine E ^a,b   Samadzadeh tarighat, Somayeh ^a,b   Akehurst, Kristi L ^a   Chandler, Dawn S ^a,b  

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 3ALPHA; SURVIVAL MOTOR NEURON PROTEIN 1; SURVIVAL MOTOR NEURON PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN; CONTROLLED STUDY; DISEASE COURSE; EXON; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; HYPOXIA; MOTOR PERFORMANCE; MOUSE; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SKELETAL MUSCLE; SPINAL MUSCULAR ATROPHY;

ALTERNATIVE SPLICING; ANIMALS; ANOXIA; CELL LINE; DISEASE MODELS, ANIMAL; EXONS; HUMANS; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; MUSCLE, SKELETAL; MUSCULAR ATROPHY, SPINAL; OXYGEN; POINT MUTATION; SEVERITY OF ILLNESS INDEX; SURVIVAL OF MOTOR NEURON 2 PROTEIN;

MUS;

EID: 84866418075     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds263     Document Type: Article

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