메뉴 건너뛰기




Volumn 30, Issue 10, 2012, Pages 546-554

Recent advances in bone tissue engineering scaffolds

Author keywords

Biomechanical properties; Biomolecule delivery; Bone scaffolds; In vitro and in vivo studies; Osteoinduction; Vascularization

Indexed keywords

BIOMECHANICAL PROPERTIES; BONE SCAFFOLDS; IN-VITRO; OSTEOINDUCTION; VASCULARIZATION;

EID: 84866415693     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2012.07.005     Document Type: Review
Times cited : (1835)

References (80)
  • 1
    • 40149087206 scopus 로고    scopus 로고
    • Tissue engineering of bone: material and matrix considerations
    • Khan Y., et al. Tissue engineering of bone: material and matrix considerations. JBJS 2008, 90:36-42.
    • (2008) JBJS , vol.90 , pp. 36-42
    • Khan, Y.1
  • 2
    • 74249112625 scopus 로고    scopus 로고
    • A biodegradable porous composite scaffold of PGA/β-TCP for bone tissue engineering
    • Cao H., Kuboyama N. A biodegradable porous composite scaffold of PGA/β-TCP for bone tissue engineering. Bone 2010, 46:386-395.
    • (2010) Bone , vol.46 , pp. 386-395
    • Cao, H.1    Kuboyama, N.2
  • 3
    • 24644482494 scopus 로고    scopus 로고
    • The BMP signaling and in vivo bone formation
    • Cao X., Chen D. The BMP signaling and in vivo bone formation. Gene 2005, 357:1-8.
    • (2005) Gene , vol.357 , pp. 1-8
    • Cao, X.1    Chen, D.2
  • 4
    • 84857640868 scopus 로고    scopus 로고
    • The insulin and insulin-like growth factor receptor family in neoplasia: an update
    • Pollak M. The insulin and insulin-like growth factor receptor family in neoplasia: an update. Nat. Rev. Cancer 2012, 12:159-169.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 159-169
    • Pollak, M.1
  • 5
    • 80053216243 scopus 로고    scopus 로고
    • Repair of rat cranial bone defects with nHAC/PLLA and BMP-2-related peptide or rhBMP-2
    • Li J., et al. Repair of rat cranial bone defects with nHAC/PLLA and BMP-2-related peptide or rhBMP-2. J. Orthop. Res. 2011, 29:1745-1752.
    • (2011) J. Orthop. Res. , vol.29 , pp. 1745-1752
    • Li, J.1
  • 6
    • 47049097487 scopus 로고    scopus 로고
    • Vascularization in tissue engineering
    • Rouwkema J., et al. Vascularization in tissue engineering. Trends Biotechnol. 2008, 26:434-441.
    • (2008) Trends Biotechnol. , vol.26 , pp. 434-441
    • Rouwkema, J.1
  • 7
    • 79251472439 scopus 로고    scopus 로고
    • Scaffold vascularization: a challenge for three-dimensional tissue engineering
    • Bramfeldt H., et al. Scaffold vascularization: a challenge for three-dimensional tissue engineering. Curr. Med. Chem. 2010, 17:3944-3967.
    • (2010) Curr. Med. Chem. , vol.17 , pp. 3944-3967
    • Bramfeldt, H.1
  • 8
    • 24944569212 scopus 로고    scopus 로고
    • Engineering vascularized tissue
    • Jain R.K., et al. Engineering vascularized tissue. Nat. Biotechnol. 2005, 23:821-823.
    • (2005) Nat. Biotechnol. , vol.23 , pp. 821-823
    • Jain, R.K.1
  • 9
    • 1542510685 scopus 로고    scopus 로고
    • Oxygen gradients in tissue-engineered PEGT/PBT cartilaginous constructs: measurement and modeling
    • Malda J., et al. Oxygen gradients in tissue-engineered PEGT/PBT cartilaginous constructs: measurement and modeling. Biotechnol. Bioeng. 2004, 86:9-18.
    • (2004) Biotechnol. Bioeng. , vol.86 , pp. 9-18
    • Malda, J.1
  • 10
    • 84855544502 scopus 로고    scopus 로고
    • Temporal and spatial vascularization patterns of unions and nonunions: role of vascular endothelial growth factor and bone morphogenetic proteins
    • Garcia P., et al. Temporal and spatial vascularization patterns of unions and nonunions: role of vascular endothelial growth factor and bone morphogenetic proteins. J. Bone Joint Surg. Am. 2012, 94:49-58.
    • (2012) J. Bone Joint Surg. Am. , vol.94 , pp. 49-58
    • Garcia, P.1
  • 11
    • 77950654906 scopus 로고    scopus 로고
    • VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo
    • Wernike E., et al. VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo. Eur. Cell Mater. 2010, 19:30-40.
    • (2010) Eur. Cell Mater. , vol.19 , pp. 30-40
    • Wernike, E.1
  • 12
    • 37349095299 scopus 로고    scopus 로고
    • Evaluation of VEGF-mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells
    • Clarkin C.E., et al. Evaluation of VEGF-mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells. J. Cell. Physiol. 2008, 214:537-544.
    • (2008) J. Cell. Physiol. , vol.214 , pp. 537-544
    • Clarkin, C.E.1
  • 13
    • 58149271034 scopus 로고    scopus 로고
    • Effect of cell-based VEGF gene therapy on healing of a segmental bone defect
    • Li R., et al. Effect of cell-based VEGF gene therapy on healing of a segmental bone defect. J. Orthop. Res. 2009, 27:8-14.
    • (2009) J. Orthop. Res. , vol.27 , pp. 8-14
    • Li, R.1
  • 14
    • 35748971482 scopus 로고    scopus 로고
    • Bone structure and formation: A new perspective
    • Olszta M.J., et al. Bone structure and formation: A new perspective. Mater. Sci. Eng. R: Rep. 2007, 58:77-116.
    • (2007) Mater. Sci. Eng. R: Rep. , vol.58 , pp. 77-116
    • Olszta, M.J.1
  • 15
    • 0033328992 scopus 로고    scopus 로고
    • Processing of controlled porosity ceramic structures via fused deposition
    • Bose S., et al. Processing of controlled porosity ceramic structures via fused deposition. Scripta Mater. 1999, 41:1009-1014.
    • (1999) Scripta Mater. , vol.41 , pp. 1009-1014
    • Bose, S.1
  • 16
    • 0041842609 scopus 로고    scopus 로고
    • From CT scan to ceramic bone graft
    • Darsell J., et al. From CT scan to ceramic bone graft. J. Am. Ceram. Soc. 2003, 86:1076-1080.
    • (2003) J. Am. Ceram. Soc. , vol.86 , pp. 1076-1080
    • Darsell, J.1
  • 17
    • 3042782581 scopus 로고    scopus 로고
    • Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems
    • Hutmacher D.W., et al. Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems. Trends Biotechnol. 2004, 22:354-362.
    • (2004) Trends Biotechnol. , vol.22 , pp. 354-362
    • Hutmacher, D.W.1
  • 18
    • 84855815432 scopus 로고    scopus 로고
    • Effects of silica and zinc oxide doping on mechanical and biological properties of 3D printed tricalcium phosphate tissue engineering scaffolds
    • Fielding G.A., et al. Effects of silica and zinc oxide doping on mechanical and biological properties of 3D printed tricalcium phosphate tissue engineering scaffolds. Dent Mater. 2012, 28:113-122.
    • (2012) Dent Mater. , vol.28 , pp. 113-122
    • Fielding, G.A.1
  • 19
    • 84880702026 scopus 로고    scopus 로고
    • Microwave-sintered 3D printed tricalcium phosphate scaffolds for bone tissue engineering
    • doi:10.1002/term.555
    • Tarafder, S. et al. Microwave-sintered 3D printed tricalcium phosphate scaffolds for bone tissue engineering. J. Tissue Eng. Regen. Med. doi:10.1002/term.555.
    • J. Tissue Eng. Regen. Med.
    • Tarafder, S.1
  • 20
    • 77956633415 scopus 로고    scopus 로고
    • Porous tantalum structures for bone implants: Fabrication, mechanical and in vitro biological properties
    • Balla V.K., et al. Porous tantalum structures for bone implants: Fabrication, mechanical and in vitro biological properties. Acta Biomater. 2010, 6:3349-3359.
    • (2010) Acta Biomater. , vol.6 , pp. 3349-3359
    • Balla, V.K.1
  • 21
    • 34548523637 scopus 로고    scopus 로고
    • Processing and biocompatibility evaluation of laser processed porous titanium
    • Xue W., et al. Processing and biocompatibility evaluation of laser processed porous titanium. Acta Biomater. 2007, 3:1007-1018.
    • (2007) Acta Biomater. , vol.3 , pp. 1007-1018
    • Xue, W.1
  • 22
    • 33644934897 scopus 로고    scopus 로고
    • Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
    • Rezwan K., et al. Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering. Biomaterials 2006, 27:3413-3431.
    • (2006) Biomaterials , vol.27 , pp. 3413-3431
    • Rezwan, K.1
  • 23
    • 80054062393 scopus 로고    scopus 로고
    • Biomimetic nanofibrous scaffolds for bone tissue engineering
    • Holzwarth J.M., Ma P.X. Biomimetic nanofibrous scaffolds for bone tissue engineering. Biomaterials 2011, 32:9622-9629.
    • (2011) Biomaterials , vol.32 , pp. 9622-9629
    • Holzwarth, J.M.1    Ma, P.X.2
  • 24
    • 77949266031 scopus 로고    scopus 로고
    • A novel method of selecting solvents for polymer electrospinning
    • Luo C.J., et al. A novel method of selecting solvents for polymer electrospinning. Polymer 2010, 51:1654-1662.
    • (2010) Polymer , vol.51 , pp. 1654-1662
    • Luo, C.J.1
  • 25
    • 83255186805 scopus 로고    scopus 로고
    • An electrospun degradable scaffold based on a novel hydrophilic polyester for tissue-engineering applications
    • Seyednejad H., et al. An electrospun degradable scaffold based on a novel hydrophilic polyester for tissue-engineering applications. Macromol. Biosci. 2011, 11:1684-1692.
    • (2011) Macromol. Biosci. , vol.11 , pp. 1684-1692
    • Seyednejad, H.1
  • 26
    • 80055116875 scopus 로고    scopus 로고
    • Increasing the pore sizes of bone-mimetic electrospun scaffolds comprised of polycaprolactone, collagen I and hydroxyapatite to enhance cell infiltration
    • Phipps M.C., et al. Increasing the pore sizes of bone-mimetic electrospun scaffolds comprised of polycaprolactone, collagen I and hydroxyapatite to enhance cell infiltration. Biomaterials 2012, 33:524-534.
    • (2012) Biomaterials , vol.33 , pp. 524-534
    • Phipps, M.C.1
  • 27
    • 77952267041 scopus 로고    scopus 로고
    • Synthesis and electrospun fiber mats of low T(g) poly(propylene fumerate-co-propylene maleate)
    • Cicotte K.N., et al. Synthesis and electrospun fiber mats of low T(g) poly(propylene fumerate-co-propylene maleate). J. Appl. Polym. Sci. 2010, 117:1984-1991.
    • (2010) J. Appl. Polym. Sci. , vol.117 , pp. 1984-1991
    • Cicotte, K.N.1
  • 28
    • 17844400927 scopus 로고    scopus 로고
    • Porosity of 3D biomaterial scaffolds and osteogenesis
    • Karageorgiou V., Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 2005, 26:5474-5491.
    • (2005) Biomaterials , vol.26 , pp. 5474-5491
    • Karageorgiou, V.1    Kaplan, D.2
  • 29
    • 77950190285 scopus 로고    scopus 로고
    • In vivo evaluation of highly macroporous ceramic scaffolds for bone tissue engineering
    • Teixeira S., et al. In vivo evaluation of highly macroporous ceramic scaffolds for bone tissue engineering. J. Biomed. Mater. Res. 2010, 93A:567-575.
    • (2010) J. Biomed. Mater. Res. , vol.93 A , pp. 567-575
    • Teixeira, S.1
  • 30
    • 33748904647 scopus 로고    scopus 로고
    • The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity
    • Woodard J.R., et al. The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity. Biomaterials 2007, 28:45-54.
    • (2007) Biomaterials , vol.28 , pp. 45-54
    • Woodard, J.R.1
  • 31
    • 77956185486 scopus 로고    scopus 로고
    • Understanding the influence of MgO and SrO binary doping on the mechanical and biological properties of β-TCP ceramics
    • Banerjee S.S., et al. Understanding the influence of MgO and SrO binary doping on the mechanical and biological properties of β-TCP ceramics. Acta Biomater. 2010, 6:4167-4174.
    • (2010) Acta Biomater. , vol.6 , pp. 4167-4174
    • Banerjee, S.S.1
  • 32
    • 79955906407 scopus 로고    scopus 로고
    • Understanding in vivo response and mechanical property variation in MgO, SrO and SiO2 doped β-TCP
    • Bose S., et al. Understanding in vivo response and mechanical property variation in MgO, SrO and SiO2 doped β-TCP. Bone 2011, 48:1282-1290.
    • (2011) Bone , vol.48 , pp. 1282-1290
    • Bose, S.1
  • 33
    • 79955609671 scopus 로고    scopus 로고
    • The role of silicon in osteoblast-like cell proliferation and apoptosis
    • Shie M.-Y., et al. The role of silicon in osteoblast-like cell proliferation and apoptosis. Acta Biomater. 2011, 7:2604-2614.
    • (2011) Acta Biomater. , vol.7 , pp. 2604-2614
    • Shie, M.-Y.1
  • 34
    • 27644562796 scopus 로고    scopus 로고
    • Optimising bioactive glass scaffolds for bone tissue engineering
    • Jones J.R., et al. Optimising bioactive glass scaffolds for bone tissue engineering. Biomaterials 2006, 27:964-973.
    • (2006) Biomaterials , vol.27 , pp. 964-973
    • Jones, J.R.1
  • 35
    • 77956479978 scopus 로고    scopus 로고
    • Enhanced osteoblastic activity and bone regeneration using surface-modified porous bioactive glass scaffolds
    • Miguel B.S., et al. Enhanced osteoblastic activity and bone regeneration using surface-modified porous bioactive glass scaffolds. J. Biomed. Mater. Res. Part A 2010, 94A:1023-1033.
    • (2010) J. Biomed. Mater. Res. Part A , vol.94 A , pp. 1023-1033
    • Miguel, B.S.1
  • 36
    • 84855723708 scopus 로고    scopus 로고
    • Hypoxia-mimicking mesoporous bioactive glass scaffolds with controllable cobalt ion release for bone tissue engineering
    • Wu C., et al. Hypoxia-mimicking mesoporous bioactive glass scaffolds with controllable cobalt ion release for bone tissue engineering. Biomaterials 2012, 33:2076-2085.
    • (2012) Biomaterials , vol.33 , pp. 2076-2085
    • Wu, C.1
  • 37
    • 79957849133 scopus 로고    scopus 로고
    • Scaffolds for bone healing: concepts, materials and evidence
    • Lichte P., et al. Scaffolds for bone healing: concepts, materials and evidence. Injury 2011, 42:569-573.
    • (2011) Injury , vol.42 , pp. 569-573
    • Lichte, P.1
  • 38
    • 34249938497 scopus 로고    scopus 로고
    • Matrices and scaffolds for delivery of bioactive molecules in bone and cartilage tissue engineering
    • Lee S.-H., Shin H. Matrices and scaffolds for delivery of bioactive molecules in bone and cartilage tissue engineering. Adv. Drug Deliv. Rev. 2007, 59:339-359.
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , pp. 339-359
    • Lee, S.-H.1    Shin, H.2
  • 39
    • 78650185016 scopus 로고    scopus 로고
    • Cross-linking characteristics and mechanical properties of an injectable biomaterial composed of polypropylene fumarate and polycaprolactone co-polymer
    • Yan J., et al. Cross-linking characteristics and mechanical properties of an injectable biomaterial composed of polypropylene fumarate and polycaprolactone co-polymer. J. Biomater. Sci. Polym. Ed. 2011, 22:489-504.
    • (2011) J. Biomater. Sci. Polym. Ed. , vol.22 , pp. 489-504
    • Yan, J.1
  • 40
    • 33846424990 scopus 로고    scopus 로고
    • A critical review on polymer-based bio-engineered materials for scaffold development
    • Cheung H.-Y., et al. A critical review on polymer-based bio-engineered materials for scaffold development. Compos. Part B: Eng. 2007, 38:291-300.
    • (2007) Compos. Part B: Eng. , vol.38 , pp. 291-300
    • Cheung, H.-Y.1
  • 41
    • 71649090287 scopus 로고    scopus 로고
    • Polycaprolactone coated porous tricalcium phosphate scaffolds for controlled release of protein for tissue engineering
    • Xue W., et al. Polycaprolactone coated porous tricalcium phosphate scaffolds for controlled release of protein for tissue engineering. J. Biomed. Mater. Res. Part B: Appl. Biomater. 2009, 91B:831-838.
    • (2009) J. Biomed. Mater. Res. Part B: Appl. Biomater. , vol.91 B , pp. 831-838
    • Xue, W.1
  • 42
    • 77956621556 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of a novel nanosize hydroxyapatite particles/poly(ester-urethane) composite scaffold for bone tissue engineering
    • Laschke M.W., et al. In vitro and in vivo evaluation of a novel nanosize hydroxyapatite particles/poly(ester-urethane) composite scaffold for bone tissue engineering. Acta Biomater. 2010, 6:2020-2027.
    • (2010) Acta Biomater. , vol.6 , pp. 2020-2027
    • Laschke, M.W.1
  • 43
    • 77953028358 scopus 로고    scopus 로고
    • The influence hydroxyapatite nanoparticle shape and size on the properties of biphasic calcium phosphate scaffolds coated with hydroxyapatite-PCL composites
    • Roohani-Esfahani S.-I., et al. The influence hydroxyapatite nanoparticle shape and size on the properties of biphasic calcium phosphate scaffolds coated with hydroxyapatite-PCL composites. Biomaterials 2010, 31:5498-5509.
    • (2010) Biomaterials , vol.31 , pp. 5498-5509
    • Roohani-Esfahani, S.-I.1
  • 44
    • 78449271130 scopus 로고    scopus 로고
    • Highly porous titanium scaffolds for orthopaedic applications
    • Dabrowski B., et al. Highly porous titanium scaffolds for orthopaedic applications. J. Biomed. Mater. Res. Part B: Appl. Biomater. 2010, 95B:53-61.
    • (2010) J. Biomed. Mater. Res. Part B: Appl. Biomater. , vol.95 B , pp. 53-61
    • Dabrowski, B.1
  • 45
    • 48749119803 scopus 로고    scopus 로고
    • Surface modification of laser-processed porous titanium for load-bearing implants
    • Das K., et al. Surface modification of laser-processed porous titanium for load-bearing implants. Scripta Mater. 2008, 59:822-825.
    • (2008) Scripta Mater. , vol.59 , pp. 822-825
    • Das, K.1
  • 46
    • 70350489464 scopus 로고    scopus 로고
    • Revolutionizing biodegradable metals
    • Yun Y., et al. Revolutionizing biodegradable metals. Mater. Today 2009, 12:22-32.
    • (2009) Mater. Today , vol.12 , pp. 22-32
    • Yun, Y.1
  • 47
    • 34249086513 scopus 로고    scopus 로고
    • Biodegradable magnesium scaffolds: Part II: Peri-implant bone remodeling
    • Witte F., et al. Biodegradable magnesium scaffolds: Part II: Peri-implant bone remodeling. J. Biomed. Mater. Res. Part A 2007, 81A:757-765.
    • (2007) J. Biomed. Mater. Res. Part A , vol.81 A , pp. 757-765
    • Witte, F.1
  • 48
    • 34548293397 scopus 로고    scopus 로고
    • Kinetics of in vivo bone deposition by bone marrow stromal cells within a resorbable porous calcium phosphate scaffold: An X-ray computed microtomography study
    • Papadimitropoulos A., et al. Kinetics of in vivo bone deposition by bone marrow stromal cells within a resorbable porous calcium phosphate scaffold: An X-ray computed microtomography study. Biotechnol. Bioeng. 2007, 98:271-281.
    • (2007) Biotechnol. Bioeng. , vol.98 , pp. 271-281
    • Papadimitropoulos, A.1
  • 49
    • 34548066898 scopus 로고    scopus 로고
    • Ectopic bone formation in bone marrow stem cell seeded calcium phosphate scaffolds as compared to autograft and (cell seeded) allograft
    • discussion 39
    • Eniwumide J.O., et al. Ectopic bone formation in bone marrow stem cell seeded calcium phosphate scaffolds as compared to autograft and (cell seeded) allograft. Eur. Cell Mater. 2007, 14:30-38. discussion 39.
    • (2007) Eur. Cell Mater. , vol.14 , pp. 30-38
    • Eniwumide, J.O.1
  • 50
    • 80053149187 scopus 로고    scopus 로고
    • The Effect of Mesenchymal Stem Cell Osteoblastic Differentiation on the Mechanical Properties of Engineered Bone-Like Tissue
    • Naito H., et al. The Effect of Mesenchymal Stem Cell Osteoblastic Differentiation on the Mechanical Properties of Engineered Bone-Like Tissue. Tissue Eng. Part A 2011, 17:2321-2329.
    • (2011) Tissue Eng. Part A , vol.17 , pp. 2321-2329
    • Naito, H.1
  • 51
    • 82355184376 scopus 로고    scopus 로고
    • Collagen-calcium phosphate cement scaffolds seeded with umbilical cord stem cells for bone tissue engineering
    • Thein-Han W., Xu H.H.K. Collagen-calcium phosphate cement scaffolds seeded with umbilical cord stem cells for bone tissue engineering. Tissue Eng. Part A 2011, 17:2943-2954.
    • (2011) Tissue Eng. Part A , vol.17 , pp. 2943-2954
    • Thein-Han, W.1    Xu, H.H.K.2
  • 52
    • 79551574175 scopus 로고    scopus 로고
    • Bone formation and neovascularization mediated by mesenchymal stem cells and endothelial cells in critical-sized calvarial defects
    • Koob S., et al. Bone formation and neovascularization mediated by mesenchymal stem cells and endothelial cells in critical-sized calvarial defects. Tissue Eng. Part A 2011, 17:311-321.
    • (2011) Tissue Eng. Part A , vol.17 , pp. 311-321
    • Koob, S.1
  • 53
    • 61549132911 scopus 로고    scopus 로고
    • Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration
    • Kempen D.H.R., et al. Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration. Biomaterials 2009, 30:2816-2825.
    • (2009) Biomaterials , vol.30 , pp. 2816-2825
    • Kempen, D.H.R.1
  • 54
    • 51449094036 scopus 로고    scopus 로고
    • Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model
    • Patel Z.S., et al. Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model. Bone 2008, 43:931-940.
    • (2008) Bone , vol.43 , pp. 931-940
    • Patel, Z.S.1
  • 55
    • 69249088910 scopus 로고    scopus 로고
    • Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model
    • Young S., et al. Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model. Tissue Eng. Part A. 2009, 15:2347-2362.
    • (2009) Tissue Eng. Part A. , vol.15 , pp. 2347-2362
    • Young, S.1
  • 56
    • 84856240519 scopus 로고    scopus 로고
    • Insulin-like growth factor 2 promotes osteogenic cell differentiation in the parthenogenetic murine embryonic stem cells
    • Kang H., et al. Insulin-like growth factor 2 promotes osteogenic cell differentiation in the parthenogenetic murine embryonic stem cells. Tissue Eng. Part A 2012, 18:331-341.
    • (2012) Tissue Eng. Part A , vol.18 , pp. 331-341
    • Kang, H.1
  • 57
    • 84857784368 scopus 로고    scopus 로고
    • Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: a review
    • Bose S., Tarafder S. Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: a review. Acta Biomater. 2012, 8:1401-1421.
    • (2012) Acta Biomater. , vol.8 , pp. 1401-1421
    • Bose, S.1    Tarafder, S.2
  • 58
    • 77954313439 scopus 로고    scopus 로고
    • Calcium phosphate biomaterials as bone drug delivery systems: a review
    • Verron E., et al. Calcium phosphate biomaterials as bone drug delivery systems: a review. Drug Discov. Today 2010, 15:547-552.
    • (2010) Drug Discov. Today , vol.15 , pp. 547-552
    • Verron, E.1
  • 59
    • 78650877069 scopus 로고    scopus 로고
    • Targeted gene-and-host progenitor cell therapy for nonunion bone fracture repair
    • Kimelman-Bleich N., et al. Targeted gene-and-host progenitor cell therapy for nonunion bone fracture repair. Mol. Ther. 2010, 19:53-59.
    • (2010) Mol. Ther. , vol.19 , pp. 53-59
    • Kimelman-Bleich, N.1
  • 60
    • 75149145129 scopus 로고    scopus 로고
    • The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF165
    • Keeney M., et al. The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF165. Biomaterials 2010, 31:2893-2902.
    • (2010) Biomaterials , vol.31 , pp. 2893-2902
    • Keeney, M.1
  • 61
    • 78149359717 scopus 로고    scopus 로고
    • Future of local bone regeneration - protein versus gene therapy
    • Fischer J., et al. Future of local bone regeneration - protein versus gene therapy. J. Cranio-Maxillofacial Surg. 2011, 39:54-64.
    • (2011) J. Cranio-Maxillofacial Surg. , vol.39 , pp. 54-64
    • Fischer, J.1
  • 62
    • 77956644933 scopus 로고    scopus 로고
    • The effect of BMP-2 on micro- and macroscale osteointegration of biphasic calcium phosphate scaffolds with multiscale porosity
    • Lan Levengood S.K., et al. The effect of BMP-2 on micro- and macroscale osteointegration of biphasic calcium phosphate scaffolds with multiscale porosity. Acta Biomater. 2010, 6:3283-3291.
    • (2010) Acta Biomater. , vol.6 , pp. 3283-3291
    • Lan Levengood, S.K.1
  • 63
    • 49349090133 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery)
    • Bessa P.C., et al. Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery). J. Tissue Eng. Regen. Med. 2008, 2:81-96.
    • (2008) J. Tissue Eng. Regen. Med. , vol.2 , pp. 81-96
    • Bessa, P.C.1
  • 64
    • 51649106996 scopus 로고    scopus 로고
    • In vitro and in vivo release of vascular endothelial growth factor from gelatin microparticles and biodegradable composite scaffolds
    • Patel Z.S., et al. In vitro and in vivo release of vascular endothelial growth factor from gelatin microparticles and biodegradable composite scaffolds. Pharm. Res. 2008, 25:2370-2378.
    • (2008) Pharm. Res. , vol.25 , pp. 2370-2378
    • Patel, Z.S.1
  • 65
    • 84859747170 scopus 로고    scopus 로고
    • Order versus disorder: in vivo bone formation within osteoconductive scaffolds
    • Article no. 274
    • Scaglione S., et al. Order versus disorder: in vivo bone formation within osteoconductive scaffolds. Sci. Rep. 2012, 2. Article no. 274.
    • (2012) Sci. Rep. , vol.2
    • Scaglione, S.1
  • 66
    • 84865737490 scopus 로고
    • Bioceramics: from concept to clinic
    • Hench L.L. Bioceramics: from concept to clinic. J. Am. Ceram. Soc. 1991, 74:1487-1510.
    • (1991) J. Am. Ceram. Soc. , vol.74 , pp. 1487-1510
    • Hench, L.L.1
  • 67
    • 0026773209 scopus 로고
    • Structure and mechanism of alkaline phosphatase
    • Coleman J.E. Structure and mechanism of alkaline phosphatase. Annu. Rev. Biophys. Biomol. Struct. 1992, 21:441-483.
    • (1992) Annu. Rev. Biophys. Biomol. Struct. , vol.21 , pp. 441-483
    • Coleman, J.E.1
  • 68
    • 77957281528 scopus 로고    scopus 로고
    • Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in diseases of the skeleton
    • Chanda D., et al. Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in diseases of the skeleton. J. Cell. Biochem. 2010, 111:249-257.
    • (2010) J. Cell. Biochem. , vol.111 , pp. 249-257
    • Chanda, D.1
  • 69
    • 36249021493 scopus 로고    scopus 로고
    • Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair-current views
    • Phinney D.G., Prockop D.J. Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair-current views. Stem Cells 2007, 25:2896-2902.
    • (2007) Stem Cells , vol.25 , pp. 2896-2902
    • Phinney, D.G.1    Prockop, D.J.2
  • 70
    • 56349114812 scopus 로고    scopus 로고
    • Extracellular matrix as a biological scaffold material: Structure and function
    • Badylak S.F., et al. Extracellular matrix as a biological scaffold material: Structure and function. Acta Biomater. 2009, 5:1-13.
    • (2009) Acta Biomater. , vol.5 , pp. 1-13
    • Badylak, S.F.1
  • 71
    • 70849099495 scopus 로고    scopus 로고
    • The extracellular matrix: not just pretty fibrils
    • Hynes R.O. The extracellular matrix: not just pretty fibrils. Science 2009, 326:1216-1219.
    • (2009) Science , vol.326 , pp. 1216-1219
    • Hynes, R.O.1
  • 72
    • 61649100307 scopus 로고    scopus 로고
    • The FGF family: biology, pathophysiology and therapy
    • Beenken A., Mohammadi M. The FGF family: biology, pathophysiology and therapy. Nat. Rev. Drug Discov. 2009, 8:235-253.
    • (2009) Nat. Rev. Drug Discov. , vol.8 , pp. 235-253
    • Beenken, A.1    Mohammadi, M.2
  • 73
    • 79952281645 scopus 로고    scopus 로고
    • Mesenchymal stem cells from adipose and bone marrow promote angiogenesis via distinct cytokine and protease expression mechanisms
    • Kachgal S., Putnam A. Mesenchymal stem cells from adipose and bone marrow promote angiogenesis via distinct cytokine and protease expression mechanisms. Angiogenesis 2011, 14:47-59.
    • (2011) Angiogenesis , vol.14 , pp. 47-59
    • Kachgal, S.1    Putnam, A.2
  • 74
    • 37149036248 scopus 로고    scopus 로고
    • A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure
    • Lin G., et al. A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure. Cell Res. 2007, 17:999-1007.
    • (2007) Cell Res. , vol.17 , pp. 999-1007
    • Lin, G.1
  • 75
    • 84873610449 scopus 로고    scopus 로고
    • The role of TGF-[beta] in bone metastasis: novel therapeutic perspectives
    • Article no. 96
    • Buijs J.T., et al. The role of TGF-[beta] in bone metastasis: novel therapeutic perspectives. BoneKEy Rep. 2012, 1. Article no. 96.
    • (2012) BoneKEy Rep. , vol.1
    • Buijs, J.T.1
  • 76
    • 62649105328 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in the communication between human osteoprogenitors and endothelial cells
    • Grellier M., et al. Role of vascular endothelial growth factor in the communication between human osteoprogenitors and endothelial cells. J. Cell. Biochem. 2009, 106:390-398.
    • (2009) J. Cell. Biochem. , vol.106 , pp. 390-398
    • Grellier, M.1
  • 77
    • 0036883670 scopus 로고    scopus 로고
    • Principals of neovascularization for tissue engineering
    • Nomi M., et al. Principals of neovascularization for tissue engineering. Mol. Aspects Med. 2002, 23:463-483.
    • (2002) Mol. Aspects Med. , vol.23 , pp. 463-483
    • Nomi, M.1
  • 78
    • 82355164095 scopus 로고    scopus 로고
    • Three-dimensional visualization of bioactive glass-bone integration in a rabbit tibia model using synchrotron X-ray microcomputed tomography
    • Fu Q., et al. Three-dimensional visualization of bioactive glass-bone integration in a rabbit tibia model using synchrotron X-ray microcomputed tomography. Tissue Eng. Part A 2011, 17:3077-3084.
    • (2011) Tissue Eng. Part A , vol.17 , pp. 3077-3084
    • Fu, Q.1
  • 79
    • 42749096667 scopus 로고    scopus 로고
    • On the mechanisms of biocompatibility
    • Williams D.F. On the mechanisms of biocompatibility. Biomaterials 2008, 29:2941-2953.
    • (2008) Biomaterials , vol.29 , pp. 2941-2953
    • Williams, D.F.1
  • 80
    • 70449088920 scopus 로고    scopus 로고
    • The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering
    • Murphy C.M., et al. The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering. Biomaterials 2010, 31:461-466.
    • (2010) Biomaterials , vol.31 , pp. 461-466
    • Murphy, C.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.