Primary central nervous system vasculitis: Pathology and mechanisms

Acta Neuropathologica

Volumn 123, Issue 6, 2012, Pages 759-772

  Giannini, Caterina ^a   Salvarani, Carlo ^b   Hunder, Gene ^a   Brown, Robert D ^a  

^a MAYO CLINIC   (United States)

^b S MARIA NUOVA HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CYCLOPHOSPHAMIDE; PREDNISONE;

ADOLESCENT; ADULT; AGED; ANCA ASSOCIATED VASCULITIS; APHASIA; ATAXIA; BEHCET DISEASE; BRAIN ANGIOGRAPHY; BRAIN BIOPSY; BRAIN HEMORRHAGE; BRAIN VASCULITIS; CLINICAL FEATURE; COGNITIVE DEFECT; CONTROLLED STUDY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; FEMALE; HEADACHE; HEMIPARESIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; INFLAMMATORY INFILTRATE; MAJOR CLINICAL STUDY; MALE; MUCOCUTANEOUS LYMPH NODE SYNDROME; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PARAPLEGIA; POLYARTERITIS NODOSA; PRIMARY CENTRAL NERVOUS SYSTEM VASCULITIS; PRIORITY JOURNAL; QUADRIPLEGIA; REVIEW; SEIZURE; SENSITIVITY AND SPECIFICITY; SEX DIFFERENCE; STROKE; TRANSIENT ISCHEMIC ATTACK; VASCULAR AMYLOIDOSIS; VISUAL DISORDER;

CEREBRAL ANGIOGRAPHY; COHORT STUDIES; HUMANS; PHENOTYPE; VASCULITIS, CENTRAL NERVOUS SYSTEM;

EID: 84866411786     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-012-0973-9     Document Type: Review

References (45)

1. Alrawi A, Trobe JD, Blaivas M, Musch DC (1999) Brain biopsy in primary angiitis of the central nervous system. Neurology 53(4):858-860
2. Arthur G, Margolis G (1977) Mycoplasma-like structures in granulomatous angiitis of the central nervous system. Case reports with light and electron microscopic studies. Arch Pathol Lab Med 101(7):382-387
3. Bazille C, Keohane C, Gray F (2005) Systemic diseases and drug-induced vasculitis. In: Kalimo H (ed) Pathology and genetics, cerebrovascular diseases. ISN Neuropath Press, Basel, pp 151-162
4. Birnbaum J, Hellmann DB (2009) Primary angiitis of the central nervous system. Arch Neurol 66(6):704-709. doi:10.1001/archneurol.2009.76
5. Calabrese LH (2009) Primary angiitis of the central nervous system: reflections on 20 years of investigation. Clin Exp Rheumatol 27(1 Suppl 52):S3-S4
6. Calabrese LH, Furlan AJ, Gragg LA, Ropos TJ (1992) Primary angiitis of the central nervous system: diagnostic criteria and clinical approach. Cleve Clin J Med 59(3):293-306
7. Calabrese LH, Mallek JA (1988) Primary angiitis of the central nervous system. Report of 8 new cases, review of the literature, and proposal for diagnostic criteria. Medicine (Baltimore) 67(1):20-39
8. Cellucci T, Benseler SM (2010) Central nervous system vasculitis in children. Curr Opin Rheumatol 22(5):590-597. doi: 10.1097/BOR.0b013e32833c723d
9. Chu CT, Gray L, Goldstein LB, Hulette CM (1998) Diagnosis of intracranial vasculitis: a multi-disciplinary approach. J Neuropathol Exp Neurol 57(1):30-38
10. Cravioto H, Feigin I (1959) Noninfectious granulomatous angiitis with a predilection for the nervous system. Neurology 9:599-609
11. DiFrancesco JC, Brioschi M, Brighina L, Ruffmann C, Saracchi E, Costantino G, Galimberti G, Conti E, Curto NA, Marzorati L, Remida P, Tagliavini F, Savoiardo M, Ferrarese C (2011) Anti-Abeta autoantibodies in the CSF of a patient with CAA-related inflammation: a case report. Neurology 76(9):842-844. doi: 10.1212/WNL.0b013e31820e773c
12. Duna GF, Calabrese LH (1995) Limitations of invasive modalities in the diagnosis of primary angiitis of the central nervous system. J Rheumatol 22(4):662-667
13. Elbers J, Halliday W, Hawkins C, Hutchinson C, Benseler SM (2010) Brain biopsy in children with primary small-vessel central nervous system vasculitis. Ann Neurol 68(5):602-610. doi: 10.1002/ana.22075
14. Eng JA, Frosch MP, Choi K, Rebeck GW, Greenberg SM (2004) Clinical manifestations of cerebral amyloid angiopathy-related inflammation. Ann Neurol 55(2):250-256. doi:10.1002/ana. 10810
15. Ferrer I, Kaste M, Kalimo H (2008) Vascular diseases. In: Love S, Louis DN, Ellison DW (eds) Greenfield's Neuropathology, vol 1, 8th edn. Hodder Arnold, London, pp 142-146
16. Geny C, Yulis J, Azoulay A, Brugieres P, Saint-Val C, Degos JD (1991) Thalamic infarction following lingual herpes zoster. Neurology 41(11):1846
17. Gilden DH, Kleinschmidt-DeMasters BK, LaGuardia JJ, Mahalingam R, Cohrs RJ (2000) Neurologic complications of the reactivation of varicella-zoster virus. N Engl J Med 342(9):635-645. doi:10.1056/NEJM200003023420906
18. Hajj-Ali RA, Singhal AB, Benseler S, Molloy E, Calabrese LH (2011) Primary angiitis of the CNS. Lancet Neurol 10(6):561-572. doi:10.1016/S1474- 4422(11)70081-3
19. Hall S, Carlin L, Roach ES, McLean WT Jr (1983) Herpes zoster and central retinal artery occlusion. Ann Neurol 13(2):217-218. doi:10.1002/ana.410130225
20. Hermann DM, Keyvani K, van de Nes J, Weimar C, Wiltfang J, Nitsch RM, Szodorai A (2011) Brain-reactive beta-amyloid antibodies in primary CNS angiitis with cerebral amyloid angiopathy. Neurology 77(5):503-505. doi:10.1212/WNL. 0b013e31 8227b250
21. Horten B, Price RW, Jimenez D (1981) Multifocal varicellazoster virus leukoencephalitis temporally remote from herpes zoster. Ann Neurol 9(3):251-266. doi:10.1002/ana.410090308
22. Hunder GG, Salvarani C, Brown RD Jr (2010) Primary central nervous system vasculitis: is it a single disease? Ann Neurol 68(5):573-574. doi:10.1002/ana.22161
23. Iwase T, Ojika K, Mitake S, Katada E, Katano H, Mase M, Yoshida S, Ueda R (2001) Involvement of CD45RO+ T lymphocyte infiltration in a patient with primary angiitis of the central nervous system restricted to small vessels. Eur Neurol 45(3):184-185
24. Jennette JC, Falk RJ, Andrassy K, Bacon PA, Churg J, Gross WL, Hagen EC, Hoffman GS, Hunder GG, Kallenberg CG et al (1994) Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum 37(2):187-192
25. Kolodny EH, Rebeiz JJ, Caviness VS Jr, Richardson EP Jr (1968) Granulomatous angiitis of the central nervous system. Arch Neurol 19(5):510-524
26. Melanson M, Chalk C, Georgevich L, Fett K, Lapierre Y, Duong H, Richardson J, Marineau C, Rouleau GA (1996) Varicellazoster virus DNA in CSF and arteries in delayed contralateral hemiplegia: evidence for viral invasion of cerebral arteries. Neurology 47(2):569-570
27. Miller DV, Salvarani C, Hunder GG, Brown RD, Parisi JE, Christianson TJ, Giannini C (2009) Biopsy findings in primary angiitis of the central nervous system. Am J Surg Pathol 33(1):35-43. doi:10.1097/PAS.0b013e318181e097
28. Nau R, Lantsch M, Stiefel M, Polak T, Reiber H (1998) Varicella zoster virus-associated focal vasculitis without herpes zoster: recovery after treatment with acyclovir. Neurology 51(3):914-915
29. Orgogozo JM, Gilman S, Dartigues JF, Laurent B, Puel M, Kirby LC, Jouanny P, Dubois B, Eisner L, Flitman S, Michel BF, Boada M, Frank A, Hock C (2003) Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization. Neurology 61(1):46-54
30. Parisi JE, Moore PM (1994) The role of biopsy in vasculitis of the central nervous system. Semin Neurol 14(4):341-348. doi: 10.1055/s-2008-1041093
31. Rawlinson WD, Cunningham AL (1991) Contralateral hemiplegia following thoracic herpes zoster. Med J Aust 155(5):344-346
32. Ross MH, Abend WK, Schwartz RB, Samuels MA (1991) A case of C2 herpes zoster with delayed bilateral pontine infarction. Neurology 41(10):1685-1686
33. Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG (2008) Angiography-negative primary central nervous system vasculitis: a syndrome involving small cerebral vessels. Medicine (Baltimore) 87(5):264-271. doi:10.1097/MD.0b013e31818896e1
34. Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG (2008) Primary central nervous system vasculitis with prominent leptomeningeal enhancement: a subset with a benign outcome. Arthritis Rheum 58(2):595-603. doi:10.1002/art.23300
35. Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG (2008) Primary central nervous system vasculitis: comparison of patients with and without cerebral amyloid angiopathy. Rheumatology (Oxford) 47(11):1671-1677. doi:10.1093/rheumatology/ ken328
36. Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG (2008) Primary CNS vasculitis with spinal cord involvement. Neurology 70(24 Pt 2):2394-2400. doi:10.1212/01.wnl. 0000314687.69681.24
37. Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG (2011) Primary central nervous system vasculitis presenting with intracranial hemorrhage. Arthritis Rheum 63(11):3598-3606. doi: 10.1002/art.30594
38. Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG (2011) Rapidly progressive primary central nervous system vasculitis. Rheumatology (Oxford) 50(2):349-358. doi:10.1093/rheumatology/keq303
39. Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Weigand SD, Miller DV, Giannini C, Meschia JF, Huston J 3rd, Hunder GG (2007) Primary central nervous system vasculitis: analysis of 101 patients. Ann Neurol 62(5):442-451. doi:10.1002/ana.21226
40. Salvarani C, Brown RD Jr, Hunder GG (2012) Adult primary central nervous system vasculitis: an update. Curr Opin Rheumatol 24(1):46-52. doi:10.1097/BOR.0b013e32834d6d76
41. Salvarani C, Brown RD Jr, Huston J 3rd, Hunder GG (2008) Prominent perivascular enhancement in primary central nervous system vasculitis. Clin Exp Rheumatol 26(3 Suppl 49):S111
42. Scolding NJ (2009) Central nervous system vasculitis. Semin Immunopathol 31(4):527-536. doi:10.1007/s00281-009-0183-2
43. Scolding NJ, Joseph F, Kirby PA, Mazanti I, Gray F, Mikol J, Ellison D, Hilton DA, Williams TL, MacKenzie JM, Xuereb JH, Love S (2005) Abeta-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy. Brain 128(Pt 3):500-515. doi:10.1093/brain/awh379
44. Swartz RH, Bhuta SS, Farb RI, Agid R, Willinsky RA, Terbrugge KG, Butany J, Wasserman BA, Johnstone DM, Silver FL, Mikulis DJ (2009) Intracranial arterial wall imaging using high-resolution 3-Tesla contrast-enhanced MRI. Neurology 72(7):627-634. doi:10.1212/01.wnl.0000342470.69739.b3
45. Zuccoli G, Pipitone N, Haldipur A, Brown RD Jr, Hunder G, Salvarani C (2011) Imaging findings in primary central nervous system vasculitis. Clin Exp Rheumatol 29(1 Suppl 64):S104-S109