Central nervous system vasculitis in children

Current Opinion in Rheumatology

Volumn 22, Issue 5, 2010, Pages 590-597

  Cellucci, Tania ^a   Benseler, Susanne M ^a,b,c  

^a Division of Rheumatology   (Canada)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

angiitis; central nervous system; children; inflammation; vasculitis

Indexed keywords

BRAIN ANGIOGRAPHY; BRAIN BIOPSY; CENTRAL NERVOUS SYSTEM DISEASE; CHILD; CHILDHOOD DISEASE; CLINICAL FEATURE; DIFFERENTIAL DIAGNOSIS; HUMAN; PRIORITY JOURNAL; PROGNOSIS; REVIEW; VASCULITIS; VASCULITIS, CENTRAL NERVOUS SYSTEM;

CHILD; DIAGNOSIS, DIFFERENTIAL; HUMANS; PROGNOSIS; VASCULITIS, CENTRAL NERVOUS SYSTEM;

EID: 77955132925     PISSN: 10408711     EISSN: None     Source Type: Journal    
DOI: 10.1097/BOR.0b013e32833c723d     Document Type: Review

References (90)

1. Cravioto H, Feigin I. Noninfectious granulomatous angiitis with a predilection for the nervous system. Neurology 1959; 9:599-609.
2. Beresford HR, Hyman RA, Sharer L. Self-limited granulomatous angiitis of the cerebellum. Ann Neurol 1979; 5:490-492.
3. Sandhu R, Alexander WS, Hornabrook RW, Stehbens WE. Granulomatous angiitis of the CNS. Arch Neurol 1979; 36:433-435.
4. Calabrese LH, Mallek JA. Primary angiitis of the central nervous system: report of 8 new cases, review of the literature, and proposal for diagnostic criteria. Medicine 1988; 67:20-39.
5. Calabrese LH, Furlan AJ, Gragg LA, Ropos TJ. Primary angiitis of the central nervous system: diagnostic criteria and clinical approach. Cleve Clin J Med 1992; 59:293-306.
6. Matsell DG, Keene DL, Jimenez C, Humphreys P. Isolated angiitis of the central nervous system in childhood. Can J Neurol Sci 1990; 17:151-154.
7. Nishikawa M, Sakamoto H, Katsuyama J, et al. Multiple appearing and vanishing aneurysms: primary angiitis of the central nervous system. Case report. J Neurosurg 1998; 88:133-137.
8. Katsicas MM, Russo R, TaratutoA, etal. Primary angiitis of the central nervous system presenting as a mass lesion in a child. J Rheumatol 2000; 27:1297-1298.
9. Lanthier S, Lortie A, Michaud J, et al. Isolated angiitis of the CNS in children. Neurology 2001; 56:837-842.
10. Gallagher KT, Shaham B, Reiff A, etal. Primary angiitis of the central nervous system in children: 5 cases. J Rheumatol 2001; 28:616-623.
11. Riou EM, Amlie-Lefond C, Echenne B, etal. Cerebrospinal fluid analysis in the diagnosis and treatment of arterial ischemic stroke. Pediatr Neurol 2008; 38:1-9.
12. Amlie-Lefond C, Bernard TJ, Sebire G, et al. Predictors of cerebral arterio-pathy in children with arterial ischemic stroke: results of the International Pediatric Stroke study. Circulation 2009; 119:1417-1423.
13. Benseler SM, Silverman ED, Aviv RI, et al. Primary central nervous system vasculitis in children. Arthritis Rheum 2006; 54:1291-1297.
14. Cellucci T, Pullenayegum E, Tyrrell P, Benseler SM. von Willebrand factor antigen: a novel biomarker of disease activity in childhood CNS vasculitis. Arthritis Rheum 2009; 60 (S10):1573.
15. Aviv RI, Benseler SM, Silverman ED, et al. MR imaging and angiography of primary CNS vasculitis of childhood. AJNR Am J Neuroradiol 2006; 27:192-199.
16. Aviv RI, Benseler SM, deVeber G, et al. Angiography of primary central nervous system angiitis of childhood: conventional angiography versus magnetic resonance angiography at presentation. AJNR Am J Neuroradiol 2007; 28:9-15.
17. Eleftheriou D, Cox T, Saunders D, et al. Investigation of childhood central nervous system vasculitis: magnetic resonance angiography versus catheter cerebral angiography. Dev Med Child Neurol 2010 [Epub ahead of print].
18. Küker W, Gaertner S, Nagele T, et al. Vessel wall contrast enhancement: a diagnostic sign of cerebral vasculitis. Cerebrovasc Dis 2008; 26: 23-29.
19. Soon GS, Yau I, Branson H, etal. Nonprogressive primary CNS vasculitis in children: immunosuppression reduces recurrent ischemic event risk. Arthritis Rheum 2008; 58(S9):S942.
20. Bitter KJ, Epstein LG, Melin-Aldana H, et al. Cyclophosphamide treatment of primary angiitis of the central nervous system in children: report of 2 cases. J Rheumatol 2006; 33:2078-2080.
21. Sen ES, Leone V, Abinun M, etal. Treatment of primary angiitis of the central nervous system in childhood with mycophenolate mofetil. Rheumatology 2010; 49:806-811.
22. Benseler SM, deVeber G, Hawkins C, et al. Angiography-negative primary central nervous system vasculitis in children. Arthritis Rheum 2005; 52:2159-2167.
23. Hassan AS, Trobe JD, McKeever PE, Gebarski SS. Linear magnetic resonance enhancement and optic neuropathy in primary angiitis of the central nervous system. J Neuroopthalmol 2003; 23:127-131.
24. Ropper AH, Ayata C, Adelman L. Vasculitis of the spinal cord. Arch Neurol 2003; 60:1791-1794.
25. Singh S, Soloman T, Chacko G, Joseph TP. Primary angiitis of the central nervous system: an ante-mortem diagnosis. J Postgrad Med 2000; 46:272-274.
26. Moritani T, Hiwatashi A, Shrier DA, et al. CNS vasculitis and vasculopathy: efficacy and usefulness of diffusion-weighted echoplanar MR imaging. Clin Imaging 2004; 28:261-270.
27. Venkateswaran S, Hawkins C, Wassmer E. Diagnostic yield of brain biopsies in children presenting to neurology. J Child Neurol 2008; 23:253-258.
28. Hajj-Ali RA, Calabrese LH. Central nervous system vasculitis. Curr Opin Rheumatol 2009; 21:10-18.
29. Lie JT. Primary (granulomatous) angiitis of the central nervous system: a clinicopathologic analysis of 15 new cases and a review of the literature. Hum Pathol 1992; 23:164-171.
30. Elbers J, Hutchinson C, Halliday W, et al. Brain biopsies in children with small-vessel primary CNS vasculitis. Arthritis Rheum 2008; 58(S9):S712.
31. Hutchinson C, Elbers J, Kwan D, et al. Long-term outcome of children with biopsy-confirmed small vessel primary CNS vasculitis. Arthritis Rheum 2008; 58(S9):S942.
32. Rodriguez-Pla A, Stone JH. Vasculitis and systemic infections. Curr Opin Rheumatol 2006; 18:39-47.
33. Schor NF. Neurology of systemic autoimmune disorders: a pediatric perspective. Semin Pediatr Neurol 2000; 7:108-117.
34. Nadeau SE. Neurologic manifestations of systemic vasculitis. Neurol Clin 2002; 20:123-150; vi.
35. Oran I, Memis A, Parildar M, Yunten N. Multiple intracranial aneurysms in polyarteritis nodosa: MRI and angiography. Neuroradiology 1999; 41:436-439.
36. Tabarki B, Mahdhaoui A, Selmi H, et al. Kawasaki disease with predominant central nervous system involvement. Pediatr Neurol 2001; 25:239-241.
37. Goncalves C, Ferreira G, Mota C, Vilarinho A. Cerebral vasculitis in Henoch-Schonlein purpura. An Pediatr (Barc) 2004; 60:188-189.
38. Seror R, Mahr A, Ramanoelina J, et al. Central nervous system involvement in Wegener granulomatosis. Medicine (Baltimore) 2006; 85:54-65.
39. Yu HH, Lee JH, Wang LC, et al. Neuropsychiatric manifestations in pediatric systemic lupus erythematosus: a 20-year study. Lupus 2006; 15:651-657.
40. Elst EF, Kamphuis SS, Prakken BJ, et al. Case report: severe central nervous system involvement in juvenile dermatomyositis. J Rheumatol 2003; 28:207-211.
41. Regan M, Haque U, Pomper M, et al. Central nervous system vasculitis as a complication of refractory dermatomyositis. J Rheumatol 2001; 28:207-211.
42. Krespi Y, Akman-Demir G, Poyraz M, et al. Cerebral vasculitis and ischaemic stroke in Behcet's disease: report of one case and review of the literature. Eur J Neurol 2001; 8:719-722.
43. Saltik S, Saip S, Kocer N, et al. MRI findings in pediatric neuro-Behcet's disease. Neuropediatrics 2004; 35:190-193.
44. Nomoto T, Nagao T, Hirabayashi K, et al. Cerebral arteriopathy with extra-cranial artery involvement in a patient with ulcerative colitis. J Neurol Sci 2006; 243:87-89
45. Benseler SM, Silverman ED. Neuropsychiatric involvement in pediatric systemic lupus erythematosus. Lupus 2007; 16:564-571.
46. Avcin T, Benseler SM, Tyrrell PN, et al. A follow-up study of antiphospholipid antibodies and associated neuropsychiatric manifestations in 137 children with systemic lupus erythematosus. Arthrit Care Res 2008; 59:206-213.
47. Steens SC, Bosma GP, ten Cate R, et al. A neuroimaging follow up study of a patient with juvenile central nervous system systemic lupus erythematosus. Ann Rheum Dis 2003; 62:583-586.
48. Rosen CL, DePalma L, Morita A. Primary angiitis of the central nervous system as a first presentation in Hodgkin's disease: a case report and review of the literature. Neurosurgery 2000; 46:1504-1508; discussion 1508-1510.
49. Power DG, Mullholland PJ, Sheehy N, et al. Relapsing granulomatous angiitis of the central nervous system in a patient while in remission from Hodgkin lymphoma. Ir Med J 2006; 99:282.
50. Ma M, Barnes G, Pulliam J, et al. CNS angiitis in graft vs host disease. Neurology 2002; 59:1994-1997.
51. Chang CJ, Chang WN, Huang LT, et al. Cerebral infarction in perinatal and childhood bacterial meningitis. Q J Med 2003; 96:755-762.
52. Starke JR. Tuberculosis of the central nervous system in children. Semin Pediatr Neurol 1999; 6:318-331.
53. Gilden DH, Kleinschmidt-DeMasters BK, LaGuardia JJ, et al. Neurologic complications of the reactivation of varicella-zoster virus. N Engl J Med 2000; 342:635-645.
54. Lanthier S, Armstrong D, Domi T, deVeber G. Postvaricella arteriopathy of childhood: natural history of vascular stenosis. Neurology 2005; 64:660-663.
55. Nagel MA, Forghani B, Mahalingam R, et al. The value of detecting anti-VZV IgG antibody in CSF to diagnose VZV vasculopathy. Neurology 2007; 68:1069-1073.
56. Heinrich A, Khaw AV, Ahrens N, et al. Cerebral vasculitis as the only manifestation of Borrelia burgdorferi infection in a 17-year-old patient with basal ganglia infarction. Eur Neurol 2003; 50:109-112.
57. Bloom BJ, Wyckoff PM, Meissner HC, Steere AC. Neurocognitive abnormalities in children after classic manifestations of lyme disease. Pediatr Infect Dis J 1998; 17:189-196.
58. Rafay MF, Armstrong D, Deveber G, etal. Craniocervical arterial dissection in children: clinical and radiographic presentation and outcome. J Child Neurol 2006; 21:8-16.
59. Kirkham FJ, Hogan AM. Risk factors for arterial ischemic stroke in childhood. CNS Spectr 2004; 9:451-464.
60. Fuh B, Lurito J, Grossi M, etal. Bilateral internal carotid artery occlusions in a pediatric patient with refractory acute myeloid leukemia. Pediatr Blood Cancer 2010; 54:770-772.
61. Kraemer M, Heienbrok W, Berlit P. Moyamoya disease in Europeans. Stroke 2008; 39:3193-3200.
62. Gupta R, Kumari R, Gupta N, etal. Moyamoya disease: magnetic resonance imaging and magnetic resonance angiographic features. J Indian Med Assoc 2006; 104:198-199.
63. Begelman SM, Olin JW. Fibromuscular dysplasia. Curr Opin Rheumatol 2000; 12:41-47.
64. Miller ST, Macklin EA, Pegelow CH, et al. Silent infarction as a risk factor for overt stroke in children with sickle cell anemia: a report from the Cooperative Study of Sickle Cell Disease. J Pediatr 2001; 139:385-390.
65. Hillery CA, Panepinto JA. Pathophysiology of stroke in sickle cell disease. Microcirculation 2004; 11:195-208.
66. Calabrese LH, Dodick DW, Schwedt TJ, Singhal AB. Narrative review: reversible cerebral vasoconstriction syndromes. Ann Intern Med 2007; 146:34-44.
67. Kirton A, Diggle J, Hu W, Wirrell E. A pediatric case of reversible segmental cerebral vasoconstriction. Can J Neurol Sci 2006; 33:250-253.
68. Catterall WA, Dib-Hajj S, Meisler MH, Pietrobon D. Inherited neuronal ion channelopathies: new windows on complex neurological disease. J Neurosci 2008; 28:11768-11777.
69. Testai FD, Gorelick PB. Inherited metabolic disorders and stroke part 1: Fabry disease and mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. Arch Neurol 2010; 67:19-24.
70. Testai FD, Gorelick PB. Inherited metabolic disorders and stroke part 2: homocystinuria, organic acidurias, and urea cycle disorders. Arch Neurol 2010; 67:148-153
71. This is an excellent review (along with the preceding reference) of inherited metabolic disorders associated with stroke. Pantoni L, Pescini F, Nannucci S, et al. Comparison of clinical, familial, and MRI features of CADASIL and NOTCH3-negative patients. Neurology 2010; 74:57-63.
72. Golomb MR, Sokol DK, Walsh LE, et al. Recurrent hemiplegia, normal MRI, and NOTCH3 mutation in a 14-year-old: is this early CADASIL? Neurology 2004; 62:2331-2332.
73. Granild-Jensen J, Jensen UB, Schwartz M, Hansen US. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy resulting in stroke in an 11 year-old male. Dev Med Child Neurol 2010; 51:754-757.
74. Muscal E, Brey RL Neurologic manifestations of systemic lupus erythematosus in children and adults. Neurol Clin 2010; 28:61-73.
75. Baumann RJ, Robertson WC Jr. Neurosarcoid presents differently in children than in adults. Pediatrics 2003; 112:e480-e486.
76. Hu WT, Murray JA, Greenaway MC, et al. Cognitive impairment and celiac disease. Arch Neurol 2006; 63:1440-1446.
77. Tenembaum S, Chitnis T, Ness J, Hahn JS. Acute disseminated encephalomyelitis. Neurology 2007; 68:S23-S36.
78. Dale RC, Brilot F, Banwell B. Pediatric central nervous system inflammatory demyelination: acute disseminated encephalomyelitis, clinically isolated syn dromes, neuromyelitis optica, and multiple sclerosis. Curr Opin Neurol 2009; 22:233-240.
79. Atzori M, Battistella P, Perini P, et al. Clinical and diagnostic aspects of multiple sclerosis and acute monophasic encephalomyelitis in pediatric patients: a single centre prospective study. Mult Scler 2009; 15:363-370.
80. Callen DJ, Shroff MM, Branson HM, et al. MRI in the diagnosis of pediatric multiple sclerosis. Neurology 2009; 72:961-967.
81. Graus F, Saiz A, Dalmau J. Antibodies and neuronal autoimmune disorders of the CNS. J Neurol 2010; 257:509-517.
82. Florance NR, Davis RL, Lam C, et al. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents. Ann Neurol 2009; 66:11-18.
83. Dalmau J, Gleichman AJ, Hughes EG, et al. Anti-NMDA receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol 2008; 7:1091-1098.
84. Wingerchuk DM, Lennon VA, Luchinetti CF, et al. The spectrum of neuromyelitis optica. Lancet Neurol 2007; 6:805-815.
85. Banwell B, Tenembaum S, Lennon VA, et al. Neuromyelitis optic-IgG in childhood inflammatory demyelinating CNS disorders. Neurology 2008; 70:344-352.
86. Graber DJ, Levy M, Kerr D, Wade WF. Neuromyelitis optica pathogenesis and aquaporin 4. J Neuroinflamm 2008; 5:22.
87. Vincent A, Buckley C, Schott JM, et al. Potassium channel antibody-associated encephalopathy: a potentially immunotherapy-responsive form of limbic encephalitis. Brain 2004; 127:701-712.
88. Kroll-Seger J, Bien CG, Huppertz HJ. Nonparaneoplastic limbic encephalitis associated to antibodies against potassium channels leading to bilateral hip-pocampal sclerosis in a prepubertal girl. Epileptic Disord 2009; 11:54-59.
89. Bataller L, Galliano R, García-Escrig M, etal. Reversible paraneoplastic limbic encephalitis associated with antibodies to the AMPA receptor. Neurology 2010; 74:265-267.
90. Lancaster E, Lai M, Peng X, etal. Antibodies to the GABAB receptor in limbic encephalitis with seizures: case series and characterization of the antigen. Lancet Neurol 2010; 9:67-76.