Inactivation of the dual Bmp/Wnt inhibitor Sostdc1 enhances pancreatic islet function

American Journal of Physiology - Endocrinology and Metabolism

Volumn 303, Issue 6, 2012, Pages

  Henley, Kathryn D ^a   Gooding, Kimberly A ^a   Economides, Aris N ^d   Gannon, Maureen ^a,b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

cell function; Bmp; Sclerostin domain containing 1; Type 2 diabetes; Wnt

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CONNECTIVE TISSUE GROWTH FACTOR; PROTEIN SCLEROSTIN DOMAIN CONTAINING 1; SCLEROSTIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; EMBRYO; GENE; GENE EXPRESSION; GENE INACTIVATION; GLUCOSE HOMEOSTASIS; INSULIN RELEASE; LIPID DIET; METABOLIC STRESS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PANCREAS ISLET DISEASE; PANCREATIC ISLET DYSMORPHOGENESIS; PRIORITY JOURNAL; SCLEROSTIN DOMAIN CONTAINING 1 GENE; UPREGULATION;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CONNECTIVE TISSUE GROWTH FACTOR; DIET, HIGH-FAT; GENE EXPRESSION REGULATION; GENE KNOCK-IN TECHNIQUES; GLUCOSE INTOLERANCE; INSULIN; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; ISLETS OF LANGERHANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MUTANT PROTEINS; SIGNAL TRANSDUCTION; TISSUE CULTURE TECHNIQUES; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84866403676     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00531.2011     Document Type: Article

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