Acute regulation of activin A and its binding protein, follistatin, in serum and tissues following lipopolysaccharide treatment of adult male mice

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 303, Issue 6, 2012, Pages

  Wu, Hui ^a   Chen, Yi ^a   Winnall, Wendy R ^a   Phillips, David J ^a   Hedger, Mark P ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Activin a; Follistatin; Inflammation; Lipopolysaccharide; Tumor necrosis factor

Indexed keywords

ACTIVIN A; CYCLOHEXIMIDE; DACTINOMYCIN; FOLLISTATIN; LIPOPOLYSACCHARIDE; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW; CIRCULATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; INFLAMMATION; LIVER; LUNG; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN PROCESSING; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERUM; TISSUES;

ACTIVINS; ANIMALS; DACTINOMYCIN; FOLLISTATIN; GENE EXPRESSION REGULATION; LIPOPOLYSACCHARIDES; MALE; MICE; PROTEIN SUBUNITS; RNA, MESSENGER;

EID: 84866388271     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00478.2011     Document Type: Article

References (46)

1. Andonegui G, Bonder CS, Green F, Mullaly SC, Zbytnuik L, Raharjo E, Kubes P. Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs. J Clin Invest 111: 1011-1020, 2003.
2. Aoki F, Kurabayashi M, Hasegawa Y, Kojima I. Attenuation of bleomycin-induced pulmonary fibrosis by follistatin. Am J Respir Crit Care Med 172: 713-720, 2005.
3. Bae HB, Jeong CW, Li M, Kim HS, Kwak SH. Effects of urinary trypsin inhibitor on lipopolysaccharide-induced acute lung injury in rabbits. Inflammation 35: 176-182, 2011.
4. Chen Y, Wu H, Winnall WR, Loveland KL, Makanji Y, Phillips DJ, Smith JA, Hedger MP. Tumour necrosis factor-α stimulates human neutrophils to release preformed activin A. Immunol Cell Biol 89: 889-896, 2011.
5. Corallini S, Taranta A, Bellomo F, Palma A, Pastore A, Emma F. Transcriptional and posttranscriptional regulation of the CTNS gene. Pediatr Res 70: 130-135, 2011.
6. Craythorn RG, Girling JE, Hedger MP, Rogers PAW, Winnall WR. An RNA spiking method demonstrates that 18S rRNA is regulated by progesterone in the mouse uterus. Mol Hum Reprod 15: 757-761, 2009.
7. Dohi T, Ejima C, Kato R, Kawamura YI, Kawashima R, Mizutani N, Tabuchi Y, Kojima I. Therapeutic potential of follistatin for colonic inflammation in mice. Gastroenterology 128: 411-423, 2005.
8. Erämaa M, Hurme M, Stenman UH, Ritvos O. Activin A/erythroid differentiation factor is induced during human monocyte activation. J Exp Med 176: 1449-1452, 1992.
9. Hardy CL, O'Connor AE, Yao J, Sebire K, de Kretser DM, Rolland JM, Anderson GP, Phillips DJ, O'Hehir RE. Follistatin is a candidate endogenous negative regulator of activin A in experimental allergic asthma. Clin Exp Allergy 36: 941-950, 2006.
10. Hedger MP, Winnall WR, Phillips DJ, de Kretser DM. The regulation and functions of activin and follistatin in inflammation and immunity. Vitam Horm 85: 255-297, 2011.
11. Hosoi T, Inoue S, Hoshino S, Ouchi Y, Orimo H. Immunohistochemical detection of activin A in osteoclasts. Gerontology 42 Suppl 1: 20-24, 1996.
12. Jones KL, de Kretser DM, Clarke IJ, Scheerlinck JPY, Phillips DJ. Characterisation of the rapid release of activin A following acute lipopolysaccharide challenge in the ewe. J Endocrinol 182: 69-80, 2004.
13. Jones KL, Mansell A, Patella S, Scott BJ, Hedger MP, de Kretser D, Phillips DJ. Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia. Proc Natl Acad Sci USA 104: 16239-16244, 2007.
14. Kariyawasam HH, Pegorier S, Barkans J, Xanthou G, Aizen M, Ying S, Kay AB, Lloyd CM, Robinson DS. Activin and transforming growth factor-α signaling pathways are activated after allergen challenge in mild asthma. J Allergy Clin Immunol 124: 454-462, 2009.
15. Keelan JA, Zhou RL, Evans LW, Groome NP, Mitchell MD. Regulation of activin A, inhibin A, and follistatin production in human amnion and choriodecidual explants by inflammatory mediators. J Soc Gynecol Investig 7: 291-296, 2000.
16. Kenny EF, O'Neill LAJ. Signalling adaptors used by Toll-like receptors: an update. Cytokine 43: 342-349, 2008.
17. Knight PG, Muttukrishna S, Groome NP. Development and application of a two-site enzyme immunoassay for the determination of 'total' activin-A concentrations in serum and follicular fluid. J Endocrinol 148: 267-279, 1996.
18. Matsuse T, Ikegami A, Ohga E, Hosoi T, Oka T, Kida K, Fukayama M, Inoue S, Nagase T, Ouchi Y, Fukuchi Y. Expression of immunoreactive activin A protein in remodeling lesions associated with interstitial pulmonary fibrosis. Am J Pathol 148: 707-713, 1996.
19. Meunier H, Rivier C, Evans RM, Vale W. Gonadal and extragonadal expression of inhibin alpha, beta A, and beta B subunits in various tissues predicts diverse functions. Proc Natl Acad Sci USA 85: 247-251, 1988.
20. Michel U, Ebert S, Phillips D, Nau R. Serum concentrations of activin and follistatin are elevated and run in parallel in patients with septicemia. Eur J Endocrinol 148: 559-564, 2003.
21. Michel U, Schneider O, Kirchhof C, Meisel S, Smirnov A, Wiltfang J, Rieckmann P. Production of follistatin in porcine endothelial cells: differential regulation by bacterial compounds and the synthetic glucocorticoid RU 28362. Endocrinology 137: 4925-4934, 1996.
22. Nüsing RM, Barsig J. Induction of prostanoid, nitric oxide, and cytokine formation in rat bone marrow derived macrophages by activin A. Br J Pharmacol 127: 919-926, 1999.
23. Nüsing RM, Mohr S, Ullrich V. Activin A and retinoic acid synergize in cyclooxygenase-1 and thromboxane synthase induction during differentiation of J774.1 macrophages. Eur J Biochem 227: 130-136, 1995.
24. O'Connor AE, McFarlane JR, Hayward S, Yohkaichiya T, Groome NP, de Kretser DM. Serum activin A and follistatin concentrations during human pregnancy: a cross-sectional and longitudinal study. Hum Reprod 14: 827-832, 1999.
25. Okuma Y, O'Connor AE, Hayashi T, Loveland KL, de Kretser DM, Hedger MP. Regulated production of activin A and inhibin B throughout the cycle of the seminiferous epithelium in the rat. J Endocrinol 190: 331-340, 2006.
26. Okuma Y, Saito K, O'Connor AE, Phillips DJ, de Kretser DM, Hedger MP. Reciprocal regulation of activin A and inhibin B by interleukin-1 (IL-1) and follicle-stimulating hormone (FSH) in rat Sertoli cells in vitro. J Endocrinol 185: 99-110, 2005.
27. Patella S, Phillips DJ, Tchongue J, de Kretser DM, Sievert W. Follistatin attenuates early liver fibrosis: effects on hepatic stellate cell activation and hepatocyte apoptosis. Am J Physiol Gastrointest Liver Physiol 290: G137-G144, 2006.
28. Phillips DJ, de Kretser DM, Pfeffer A, Ng Chie W, Moore LG. Follistatin has a biphasic response but follicle-stimulating hormone is unchanged during an inflammatory episode in growing lambs. J Endocrinol 156: 77-82, 1998.
29. Phillips DJ, Hedger MP, McFarlane JR, Klein R, Clarke IJ, Tilbrook AJ, Nash AD, de Kretser DM. Follistatin concentrations in male sheep increase following sham castration/castration or injection of interleukin-1β. J Endocrinol 151: 119-124, 1996.
30. Robson NC, Phillips DJ, McAlpine T, Shin A, Svobodova S, Toy T, Pillay V, Kirkpatrick N, Zanker D, Wilson K, Helling I, Wei H, Chen W, Cebon J, Maraskovsky E. Activin-A: a novel dendritic cell-derived cytokine that potently attenuates CD40 ligand-specific cytokine and chemokine production. Blood 111: 2733-2743, 2008.
31. Sabroe I, Whyte MKB. Toll-like receptor (TLR)-based networks regulate neutrophilic inflammation in respiratory disease. Biochem Soc Trans 35: 1492-1495, 2007.
32. Sacher JA, Morgan EJ, De LaRosa D. Paradoxical effect of actinomycin D: regulation of synthesis of wound RNase at translation in turnip tissue. Plant Physiol 56: 442-449, 1975.
33. Savov JD, Gavett SH, Brass DM, Costa DL, Schwartz DA. Neutrophils play a critical role in development of LPS-induced airway disease. Am J Physiol Lung Cell Mol Physiol 283: L952-L962, 2002.
34. Schneider O, Nau R, Michel U. Comparative analysis of follistatin-, activin beta A-and activin beta B-mRNA steady-state levels in diverse porcine tissues by multiplex S1 nuclease analysis. Eur J Endocrinol 142: 537-544, 2000.
35. Shao LE, Frigon NL Jr, Yu A, Palyash J, Yu J. Contrasting effects of inflammatory cytokines and glucocorticoids on the production of activin A in human marrow stromal cells and their implications. Cytokine 10: 227-235, 1998.
36. Sidis Y, Tortoriello DV, Holmes WE, Pan Y, Keutmann HT, Schneyer AL. Follistatin-related protein and follistatin differentially neutralize endogenous vs. exogenous activin. Endocrinology 143: 1613-1624, 2002.
37. Sugama S, Takenouchi T, Kitani H, Fujita M, Hashimoto M. Activin as an anti-inflammatory cytokine produced by microglia. J Neuroimmunol 192: 31-39, 2007.
38. Tuuri T, Erämaa M, Hildén K, Ritvos O. The tissue distribution of activin beta A-and beta B-subunit and follistatin messenger ribonucleic acids suggests multiple sites of action for the activin-follistatin system during human development. J Clin Endocrinol Metab 78: 1521-1524, 1994.
39. Wada M, Shintani Y, Kosaka M, Sano T, Hizawa K, Saito S. Immunohistochemical localization of activin A and follistatin in human tissues. Endocr J 43: 375-385, 1996.
40. Wilson KM, Smith AI, Phillips DJ. Stimulatory effects of lipopolysaccharide on endothelial cell activin and follistatin. Mol Cell Endocrinol 253: 30-35, 2006.
41. Winnall WR, Muir JA, Liew S, Hirst JJ, Meachem SJ, Hedger MP. Effects of chronic celecoxib on testicular function in normal and lipopolysaccharide-treated rats. Int J Androl 32: 542-555, 2009.
42. Yamashita N, Nakajima T, Takahashi H, Kaneoka H, Mizushima Y, Sakane T. Effects of activin A on IgE synthesis and cytokine production by human peripheral mononuclear cells. Clin Exp Immunol 94: 214-219, 1993.
43. Yamashita T, Takahashi S, Ogata E. Expression of activin A/erythroid differentiation factor in murine bone marrow stromal cells. Blood 79: 304-307, 1992.
44. Yu J, Dolter KE. Production of activin A and its roles in inflammation and hematopoiesis. Cytokines Cell Mol Ther 3: 169-177, 1997.
45. Zhang X, Christenson LK, Nothnick WB. Regulation of MMP-9 expression and activity in the mouse uterus by estrogen. Mol Reprod Dev 74: 321-331, 2007.
46. Zuckerman SH, Shellhaas J, Butler LD. Differential regulation of lipopolysaccharide-induced interleukin 1 and tumor necrosis factor synthesis: effects of endogenous and exogenous glucocorticoids and the role of the pituitary-adrenal axis. Eur J Immunol 19: 301-305, 1989.