Design, synthesis, and anticonvulsant screening of some substituted piperazine and aniline derivatives of 5-phenyloxazolidin- 2,4-diones and 5,5-diphenylimidazolidin-2,4 diones

Medicinal Chemistry Research

Volumn 21, Issue 10, 2012, Pages 2807-2822

  Dhanawat, Meenakshi ^a   Banerjee, Anupam G ^a   Shrivastava, S K ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

Aniline derivative; Anticonvulsants; Heteroaryl; MES; Neurotoxicity; Piperazine derivative

Indexed keywords

3 (2 CHLORO ETHYL) 5 PHENYL OXAZOLIDINE 2,4 DIONE; 3 (2 CHLORO ETHYL) 5,5 DIPHENYL IMIDAZOLIDINE 2,4 DIONE; 3 [2 (4 CHLORO PHENYLAMINO)ETHYL] 5 PHENYL OXAZOLIDINE 2,4 DIONE; 3 [2 (4 CHLORO PHENYLAMINO)ETHYL] 5,5 DIPHENYL IMIDAZOLIDINE 2,4 DIONE; 3 [2 (4 FLUORO PHENYLAMINO)ETHYL] 5,5 DIPHENYL IMIDAZOLIDINE 2,4 DIONE; 3 [2 (4 HYDROXY PHENYLAMINO)ETHYL] 5 PHENYL OXAZOLIDINE 2,4 DIONE; 3 [2 (4 HYDROXY PHENYLAMINO)ETHYL] 5,5 DIPHENYL IMIDAZOLIDINE 2,4 DIONE; 3 [2 (4 METHOXY PHENYLAMINO)ETHYL] 5 PHENYL OXAZOLIDINE 2,4 DIONE; 3 [2 (4 METHOXY PHENYLAMINO)ETHYL] 5,5 DIPHENYL IMIDAZOLIDINE 2,4 DIONE; 3 [2 [4 (4 CHLORO PHENYL)PIPERAZIN 1 YL]ETHYL] 5 PHENYLOXAZOLIDINE 2,4 DIONE; 3 [2 [4 (4 CHLORO PHENYL)PIPERAZIN 1 YL]ETHYL] 5,5 DIPHENYLIMIDAZOLIDINE 2,4 DIONE; 3 [2 [4 (4 FLUORO PHENYL)PIPERAZIN 1 YL] ETHYL] 5,5 DIPHENYL IMIDAZOLIDINE 2,4 DIONE; 3 [2 [4 (4 FLUORO PHENYL)PIPERAZIN 1 YL]ETHYL] 5 PHENYLOXAZOLIDINE 2,4 DIONE; 3 [2 [4 (4 HYDROXY PHENYL)PIPERAZIN 1 YL]ETHYL] 5 PHENYLOXAZOLIDINE 2,4 DIONE; 3 [2 [4 (4 HYDROXY PHENYL)PIPERAZIN 1 YL]ETHYL] 5,5 DIPHENYLIMIDAZOLIDINE 2,4 DIONE; 3 [2 [4 (4 NITRO PHENYL)PIPERAZIN 1 YL]ETHYL] 5 PHENYLOXAZOLIDINE 2,4 DIONE; 3 [2 [4 (4 NITRO PHENYL)PIPERAZIN 1 YL]ETHYL] 5,5 DIPHENYLIMIDAZOLIDINE 2,4 DIONE; 5 PHENYL 3 [2 (4 PARA TOLYL PIPERAZIN 1 YL)ETHYL]OXAZOLIDINE 2,4 DIONE; 5 PHENYL OXAZOLIDINE 2,4 DIONE; 5,5 DIPHENYL 3 [2 (4 PARA TOLYL PIPERAZIN 1 YL)ETHYL] IMIDAZOLIDINE 2,4 DIONE; 5,5 DIPHENYL 3 [2 (4 PYRIDIN 2 YL PIPERAZIN 1 YL)ETHYL] IMIDAZOLIDINE 2,4 DIONE; 5,5 DIPHENYL IMIDAZOLIDINE 2,4 DIONE; ANTICONVULSIVE AGENT; HYDANTOIN DERIVATIVE; HYDROXY PHENYL ACETIC ACID ETHYL ESTER; KETANSERIN TARTRATE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; OXAZOLIDINEDIONE DERIVATIVE; PHENYTOIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC SHOCK; HEAD TWITCH; IN VIVO STUDY; LIPOPHILICITY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; RAT; RECTUM TEMPERATURE; ROTAROD TEST; SEIZURE;

EID: 84866382246     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-011-9805-z     Document Type: Article

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