Valproic acid but not D-cycloserine facilitates sleep-dependent offline learning of extinction and habituation of conditioned fear in humans

Neuropharmacology

Volumn 64, Issue , 2013, Pages 424-431

  Kuriyama, Kenichi ^a   Honma, Motoyasu ^a   Yoshiike, Takuya ^a   Kim, Yoshiharu ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

Author keywords

d Cycloserine; Fear conditioning; Fear extinction; Off line learning; Sleep dependent memory consolidation; Valproic acid

Indexed keywords

CYCLOSERINE; PLACEBO; VALPROIC ACID;

ADULT; ANXIETY DISORDER; ARTICLE; COGNITIVE THERAPY; CONDITIONING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG INDICATION; ELECTRIC SHOCK; EXPOSURE; FEAR; FEMALE; HABITUATION; HUMAN; HUMAN EXPERIMENT; LEARNING; MALE; MEMORY CONSOLIDATION; NORMAL HUMAN; OFFLINE LEARNING; OUTCOME ASSESSMENT; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECALL; REINFORCEMENT; SKIN CONDUCTANCE; SLEEP WAKING CYCLE; STIMULUS RESPONSE; VISUAL STIMULATION;

ADULT; ANTI-ANXIETY AGENTS; ANXIETY DISORDERS; CYCLOSERINE; EXCITATORY AMINO ACID AGONISTS; EXTINCTION, PSYCHOLOGICAL; FEAR; FEMALE; HABITUATION, PSYCHOPHYSIOLOGIC; HISTONE DEACETYLASE INHIBITORS; HUMANS; LEARNING; MALE; MEMORY, EPISODIC; MOLECULAR TARGETED THERAPY; NOOTROPIC AGENTS; RECEPTORS, N-METHYL-D-ASPARTATE; SINGLE-BLIND METHOD; SLEEP; STUDENTS; VALPROIC ACID; YOUNG ADULT;

EID: 84866366057     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.07.045     Document Type: Article

References (58)

1. I.A. Alhaider, A.M. Aleisa, T.T. Tran, and K.A. Alkadhi Sleep deprivation prevents stimulation-induced increases of levels of P-CREB and BDNF: protection by caffeine Mol. Cell. Neurosci. 46 2011 742 751
2. A. Artola, and W. Singer Long-term potentiation and NMDA receptors in rat visual cortex Nature 330 1987 649 652
3. T.W. Bredy, and M. Barad The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear Learn. Mem. 15 2008 39 45
4. T.W. Bredy, H. Wu, C. Crego, J. Zellhoefer, Y.E. Sun, and M. Barad Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear Learn. Mem. 14 2007 268 276
5. R.A. Bryant, M.L. Moulds, R.M. Guthrie, S.T. Dang, and R.D. Nixon Imaginal exposure alone and imaginal exposure with cognitive restructuring in treatment of posttraumatic stress disorder J. Consult. Clin. Psychol. 71 2003 706 712
6. M.F. Carr, S.P. Jadhav, and L.M. Frank Hippocampal replay in the awake state: a potential substrate for memory consolidation and retrieval Nat. Neurosci. 14 2011 147 153
7. M.A. Casu, A. Sanna, G.P. Spada, M. Falzoi, R. Mongeau, and L. Pani Effects of acute and chronic valproate treatments on p-CREB levels in the rat amygdala and nucleus accumbens Brain Res. 1141 2007 15 24
8. S. Chateauvieux, F. Morceau, M. Dicato, and M. Diederich Molecular and therapeutic potential and toxicity of valproic acid J. Biomed. Biotechnol. 2010 pii, 479364
9. J.P. Chhatwal, L. Stanek-Rattiner, M. Davis, and K.J. Ressler Amygdala BDNF signaling is required for consolidation but not encoding of extinction Nat. Neurosci. 9 2006 870 872
10. M. Davis, K. Ressler, B.O. Rothbaum, and R. Richardson Effects of d-cycloserine on extinction: translation from preclinical to clinical work Biol. Psychiatry 60 2006 369 375
11. S. Diekelmann, and J. Born The memory function of sleep Nat. Rev. Neurosci. 11 2010 114 126
12. M.S. Fanselow Pavlovian conditioning, negative feedback, and blocking: mechanisms that regulate association formation Neuron 20 1998 625 627
13. E.B. Foa Prolonged exposure therapy: past, present, and future Depress. Anxiety 28 2011 1043 1047
14. A.J. Guastella, P.F. Lovibond, M.R. Dadds, P. Mitchell, and R. Richardson A randomized controlled trial of the effect of d-cycloserine on extinction and fear conditioning in humans Behav. Res. Ther. 45 2007 663 672
15. A.J. Guastella, R. Richardson, P.F. Lovibond, R.M. Rapee, J.E. Gaston, P. Mitchell, and M.R. Dadds A randomized controlled trial of d-cycloserine enhancement of exposure therapy for social anxiety disorder Biol. Psychiatry 63 2008 544 549
16. R. Guzman-Marin, Z. Ying, N. Suntsova, M. Methippara, T. Bashir, R. Szymusiak, F. Gomez-Pinilla, and D. McGinty Suppression of hippocampal plasticity-related gene expression by sleep deprivation in rats J. Physiol. 575 2006 807 819
17. M. Göttlicher Valproic acid: an old drug newly discovered as inhibitor of histone deacetylases Ann. Hematol. 83 Suppl. 1 2004 S91 S92
18. S.G. Hofmann Cognitive processes during fear acquisition and extinction in animals and humans: implications for exposure therapy of anxiety disorders Clin. Psychol. Rev. 28 2008 199 210
19. S.G. Hofmann, A.E. Meuret, J.A. Smits, N.M. Simon, M.H. Pollack, K. Eisenmenger, M. Shiekh, and M.W. Otto Augmentation of exposure therapy with d-cycloserine for social anxiety disorder Arch. Gen. Psychiatry 63 2006 298 304
20. G.S. Jeon, S.H. Park, K.J. Lee, M.S. Lee, B.G. Chun, and K.H. Shin Valproate prevents MK801-induced changes in brain-derived neurotrophic factor mRNA in the rat brain Eur. J. Pharmacol. 545 2006 142 146
21. L.K. Jornada, M. Moretti, S.S. Valvassori, C.L. Ferreira, P.T. Padilha, C.O. Arent, G.R. Fries, F. Kapczinski, and J. Quevedo Effects of mood stabilizers on hippocampus and amygdala BDNF levels in an animal model of mania induced by ouabain J. Psychiatr. Res. 44 2010 506 510
22. A. Kirkwood, M.C. Rioult, and M.F. Bear Experience-dependent modification of synaptic plasticity in visual cortex Nature 381 1996 526 528
23. U. Klotz, and K.H. Antonin Pharmacokinetics and bioavailability of sodium valproate Clin. Pharmacol. Ther. 21 1977 736 743
24. K. Kuriyama, M. Honma, S. Koyama, and Y. Kim d-cycloserine facilitates procedural learning but not declarative learning in healthy humans: a randomized controlled trial of the effect of d-cycloserine and valproic acid on overnight properties in the performance of non-emotional memory tasks Neurobiol. Learn. Mem. 95 2011 505 509
25. K. Kuriyama, M. Honma, T. Soshi, T. Fujii, and Y. Kim Effect of d-cycloserine and valproic acid on the extinction of reinstated fear-conditioned responses and habituation of fear conditioning in healthy humans: a randomized controlled trial Psychopharmacol. (Berl) 218 2011 589 597
26. M.G. Kushner, S.W. Kim, C. Donahue, P. Thuras, D. Adson, M. Kotlyar, J. McCabe, J. Peterson, and E.B. Foa D-cycloserine augmented exposure therapy for obsessive-compulsive disorder Biol. Psychiatry 62 2007 835 838
27. L. Ledgerwood, R. Richardson, and J. Cranney Effects of D-cycloserine on extinction of conditioned freezing Behav. Neurosci. 117 2003 341 349
28. L. Ledgerwood, R. Richardson, and J. Cranney d-cycloserine and the facilitation of extinction of conditioned fear: consequences for reinstatement Behav. Neurosci. 118 2004 505 513
29. J.E. LeDoux Emotion circuits in the brain Annu. Rev. Neurosci. 23 2000 155 184
30. J.L. Lee, A.L. Milton, and B.J. Everitt Reconsolidation and extinction of conditioned fear: inhibition and potentiation J. Neurosci. 26 2006 10051 10056
31. J.M. Levenson, K.J. O'Riordan, K.D. Brown, M.A. Trinh, D.L. Molfese, and J.D. Sweatt Regulation of histone acetylation during memory formation in the hippocampus J. Biol. Chem. 279 2004 40545 40559
32. F. Li, and J.Z. Tsien Memory and the NMDA receptors N. Engl. J. Med. 361 2009 302 303
33. K.D. Miller, B. Chapman, and M.P. Stryker Visual responses in adult cat visual cortex depend on N-methyl-d-aspartate receptors Proc. Natl. Acad. Sci. U. S. A. 86 1989 5183 5187
34. K.M. Myers, and M. Davis Behavioral and neural analysis of extinction Neuron 36 2002 567 584
35. K.G.S. Neir, I.G. Epstein, H. Baron, and M.G. Mulinos Absorption, distribution and excretion of cycloserine in man Antibiot. Annu. 3 1956 136 140
36. O.A. Onur, T.E. Schlaepfer, J. Kukolja, A. Bauer, H. Jeung, A. Patin, D.M. Otte, N.J. Shah, W. Maier, K.M. Kendrick, G.R. Fink, and R. Hurlemann The N-methyl-d-aspartate receptor co-agonist d-cycloserine facilitates declarative learning and hippocampal activity in humans Biol. Psychiatry 67 2010 1205 1211
37. S.P. Orr, L.J. Metzger, N.B. Lasko, M.L. Macklin, T. Peri, and R.K. Pitman De novo conditioning in trauma-exposed individuals with and without posttraumatic stress disorder J. Abnorm. Psychol. 109 2000 290 298
38. M.W. Otto, D.F. Tolin, N.M. Simon, G.D. Pearlson, S. Basden, S.A. Meunier, S.G. Hofmann, K. Eisenmenger, J.H. Krystal, and M.H. Pollack Efficacy of d-cycloserine for enhancing response to cognitive-behavior therapy for panic disorder Biol. Psychiatry 67 2010 365 370
39. L.C. Ou, and P.W. Gean Regulation of amygdala-dependent learning by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol-3-kinase Neuropsychopharmacology 31 2006 287 296
40. R.G. Phillips, and J.E. LeDoux Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning Behav. Neurosci. 106 1992 274 285
41. G.J. Quirk, R. Garcia, and F. González-Lima Prefrontal mechanisms in extinction of conditioned fear Biol. Psychiatry 60 2006 337 343
42. G.J. Quirk, and D. Mueller Neural mechanisms of extinction learning and retrieval Neuropsychopharmacology 33 2008 56 72
43. L.M. Rattiner, M. Davis, and K.J. Ressler Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learning Learn. Mem. 11 2004 727 731
44. K.J. Ressler, B.O. Rothbaum, L. Tannenbaum, P. Anderson, K. Graap, E. Zimand, L. Hodges, and M. Davis Cognitive enhancers as adjuncts to psychotherapy: use of d-cycloserine in phobic individuals to facilitate extinction of fear Arch. Gen. Psychiatry 61 2004 1136 1144
45. G. Rosenberg The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees? Cell. Mol. Life Sci. 64 2007 2090 2103
46. S. Rumpel, H. Hatt, and K. Gottmann Silent synapses in the developing rat visual cortex: evidence for postsynaptic expression of synaptic plasticity J. Neurosci. 18 1998 8863 8874
47. E. Santini, R.U. Muller, and G.J. Quirk Consolidation of extinction learning involves transfer from NMDA-independent to NMDA-dependent memory J. Neurosci. 21 2001 9009 9017
48. B.R. Sheth, N. Nguyen, and D. Janvelyan Does sleep really influence face recognition memory? PLoS One 4 2009 e5496
49. L.M. Shin, and I. Liberzon The neurocircuitry of fear, stress, and anxiety disorders Neuropsychopharmacology 35 2010 169 191
50. S. Song, J.H. Howard Jr.; and D.V. Howard Sleep does not benefit probabilistic motor sequence learning J. Neurosci. 27 2007 12475 12483
51. R. Stickgold Sleep-dependent memory consolidation Nature 437 2005 1272 1278
52. G. Tononi, and C. Cirelli Sleep function and synaptic homeostasis Sleep Med. Rev. 10 2006 49 62
53. P.D. Varga-Weisz, and P.B. Becker Chromatin-remodeling factors: machines that regulate? Curr. Opin. Cell. Biol. 10 1998 346 353
54. C.G. Vecsey, G.S. Baillie, D. Jaganath, R. Havekes, A. Daniels, M. Wimmer, T. Huang, K.M. Brown, X.Y. Li, G. Descalzi, S.S. Kim, T. Chen, Y.Z. Shang, M. Zhuo, M.D. Houslay, and T. Abel Sleep deprivation impairs cAMP signalling in the hippocampus Nature 461 2009 1122 1125
55. D.L. Walker, K.J. Ressler, K.T. Lu, and M. Davis Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of d-cycloserine as assessed with fear-potentiated startle in rats J. Neurosci. 22 2002 2343 2351
56. B.J. Wilder, and R.J. Rangel Review of valproate monotherapy in the treatment of generalized tonic-clonic seizures Am. J. Med. 84 1988 7 13
57. S. Wilhelm, U. Buhlmann, D.F. Tolin, S.A. Meunier, G.D. Pearlson, H.E. Reese, P. Cannistraro, M.A. Jenike, and S.L. Rauch Augmentation of behavior therapy with d-cycloserine for obsessive-compulsive disorder Am. J. Psychiatry 165 2008 335 341
58. X.J. Yang, and E. Seto HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention Oncogene 26 2007 5310 5318