메뉴 건너뛰기




Volumn 73, Issue 6, 2012, Pages 308-316

Preventive effects of flavonoid extracts from ilex hainanensis Merr. on rats with hepatic steatosis induced by a high-fat diet

Author keywords

hepatic steatosis; high fat diet; Ilex hainanensis Merr.

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; FATTY ACID; FLAVONOID; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ILEX HAINANENSIS EXTRACT; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; PLANT EXTRACT; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84866365058     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.21014     Document Type: Article
Times cited : (10)

References (49)
  • 1
    • 24044536090 scopus 로고    scopus 로고
    • Recent concepts in non-alcoholic fatty liver disease
    • DOI 10.1111/j.1464-5491.2005.01748.x
    • Adams LA, Angulo P,. 2005. Recent concepts in non-alcoholic fatty liver disease. Diabet Med 22: 1129-1133. (Pubitemid 41224168)
    • (2005) Diabetic Medicine , vol.22 , Issue.9 , pp. 1129-1133
    • Adams, L.A.1    Angulo, P.2
  • 2
    • 0344412841 scopus 로고    scopus 로고
    • Nonalcoholic Fatty Liver Disease in Saudi Type 2 Diabetic Subjects Attending a Medical Outpatient Clinic: Prevalence and general characteristics [2]
    • DOI 10.2337/diacare.26.12.3351
    • Akbar DH, Kawther AH,. 2003. Nonalcoholic fatty liver disease in Saudi type 2 diabetic subjects attending a medical outpatient clinic: prevalence and general characteristics. Diabetes Care 26: 3351-3352. (Pubitemid 37466902)
    • (2003) Diabetes Care , vol.26 , Issue.12 , pp. 3351-3352
    • Akbar, D.H.1    Kawther, A.H.2
  • 8
    • 0031761559 scopus 로고    scopus 로고
    • Diagnosis and interpretation of steatosis and steatohepatitis
    • Burt AD, Mutton A, Day CP,. 1998. Diagnosis and interpretation of steatosis and steatohepatitis. Semin Diagn Pathol 15: 246-258. (Pubitemid 28536758)
    • (1998) Seminars in Diagnostic Pathology , vol.15 , Issue.4 , pp. 246-258
    • Burt, A.D.1    Mutton, A.2    Day, C.P.3
  • 9
    • 33748457319 scopus 로고    scopus 로고
    • Prevalence and risk factors of nonalcoholic fatty liver disease in an adult population of Taiwan: Metabolic significance of nonalcoholic fatty liver disease in nonobese adults
    • Chen CH, Huang MH, Yang JC, Nien CK, Yang CC, Yeh YH, Yueh SK,. 2006. Prevalence and risk factors of nonalcoholic fatty liver disease in an adult population of Taiwan: metabolic significance of nonalcoholic fatty liver disease in nonobese adults. J Clin Gastroenterol 40: 745-752.
    • (2006) J Clin Gastroenterol , vol.40 , pp. 745-752
    • Chen, C.H.1    Huang, M.H.2    Yang, J.C.3    Nien, C.K.4    Yang, C.C.5    Yeh, Y.H.6    Yueh, S.K.7
  • 10
    • 72549104258 scopus 로고    scopus 로고
    • Triterpenes and flavonoids from Ilex hainanensis Merr. (Aquifoliaceae)
    • Chen XQ, Zan K, Liu H, Yang J, Lai MX, Wang Q,. 2009a. Triterpenes and flavonoids from Ilex hainanensis Merr. (Aquifoliaceae). Biochem Syst Ecol 37: 678-682.
    • (2009) Biochem Syst Ecol , vol.37 , pp. 678-682
    • Chen, X.Q.1    Zan, K.2    Liu, H.3    Yang, J.4    Lai, M.X.5    Wang, Q.6
  • 12
    • 82955231615 scopus 로고    scopus 로고
    • Chinese Pharmacopoeia Committee. Beijing: Chemical Industry Press.
    • Chinese Pharmacopoeia Committee. 2010. Chinese pharmacopoeia (part1). Beijing: Chemical Industry Press.
    • (2010) Chinese Pharmacopoeia (part1)
  • 13
    • 0033901336 scopus 로고    scopus 로고
    • Nonalcoholic red wine extract and quercetin inhibit LDL oxidation without affecting plasma antioxidant vitamin and carotenoid concentrations
    • Chopra M, Fitzsimons PE, Strain JJ, Thurnham DI, Howard AN,. 2000. Nonalcoholic red wine extract and quercetin inhibit LDL oxidation without affecting plasma antioxidant vitamin and carotenoid concentrations. Clin Chem 46 (8 Pt. 1): 1162-1170. (Pubitemid 30643320)
    • (2000) Clinical Chemistry , vol.46 , Issue.8 , pp. 1162-1170
    • Chopra, M.1    Fitzsimons, P.E.E.2    Strain, J.J.3    Thurnham, D.I.4    Howard, A.N.5
  • 14
    • 0036090972 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Clark JM, Brancati FL, Diehl AM,. 2002. Nonalcoholic fatty liver disease. Gastroenterology 122: 1649-1657. (Pubitemid 34533559)
    • (2002) Gastroenterology , vol.122 , Issue.6 , pp. 1649-1657
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.3
  • 15
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two "hits?"
    • Day CP, James OF,. 1998. Steatohepatitis: a tale of two "hits?" Gastroenterology 114: 842-845.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 16
    • 3042521502 scopus 로고    scopus 로고
    • Increased prevalence of fatty liver in arterial hypertensive patients with normal liver enzymes: Role of insulin resistance
    • DOI 10.1136/gut.2003.027086
    • Donati G, Stagni B, Piscaglia F, Venturoli N, Morselli-Labate AM, Rasciti L, Bolondi L,. 2004. Increased prevalence of fatty liver in arterial hypertensive patients with normal liver enzymes: role of insulin resistance. Gut 53: 1020-1023. (Pubitemid 38824162)
    • (2004) Gut , vol.53 , Issue.7 , pp. 1020-1023
    • Donati, G.1    Stagni, B.2    Piscaglia, F.3    Venturoli, N.4    Morselli-Labate, A.M.5    Rasciti, L.6    Bolondi, L.7
  • 17
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer H, Schaur RJ, Zollner H,. 1991. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 11: 81-128. (Pubitemid 121003917)
    • (1991) Free Radical Biology and Medicine , vol.11 , Issue.1 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 19
    • 84866427009 scopus 로고    scopus 로고
    • Preventive effects of extracts from Ilex hainanensis Merr. on rats with experimental hyperlipidemia
    • Fang RT, Wei TS,. 2011. Preventive effects of extracts from Ilex hainanensis Merr. on rats with experimental hyperlipidemia. Northwest Pharm J 26: 123-125.
    • (2011) Northwest Pharm J , vol.26 , pp. 123-125
    • Fang, R.T.1    Wei, T.S.2
  • 20
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: From steatosis to cirrhosis
    • Farrell GC, Larter CZ,. 2006. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 43 (Suppl. 1): S99-S112.
    • (2006) Hepatology , vol.43 , Issue.SUPPL. 1
    • Farrell, G.C.1    Larter, C.Z.2
  • 24
    • 34547472585 scopus 로고    scopus 로고
    • Managing nonalcoholic fatty liver disease: Recommendations for family physicians
    • Grattagliano I, Portincasa P, Palmieri VO, Palasciano G,. 2007. Managing nonalcoholic fatty liver disease: recommendations for family physicians. Can Fam Physician 53: 857-863. (Pubitemid 47164278)
    • (2007) Canadian Family Physician , vol.53 , Issue.5 , pp. 857-863
    • Grattagliano, I.1    Portincasa, P.2    Palmieri, V.O.3    Palasciano, G.4
  • 26
    • 0028068186 scopus 로고
    • Free radicals, antioxidants, and human disease: Curiosity, cause, or consequence?
    • Halliwell B,. 1994. Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? Lancet 344: 721-724.
    • (1994) Lancet , vol.344 , pp. 721-724
    • Halliwell, B.1
  • 27
    • 0031472264 scopus 로고    scopus 로고
    • Reduced progression of atherosclerosis in apolipoprotein E-deficient mice following consumption of red wine, or its polyphenols quercetin or catechin, is associated with reduced susceptibility of LDL to oxidation and aggregation
    • Hayek T, Fuhrman B, Vaya J, Rosenblat M, Belinky P, Coleman R, Elis A, Aviram M,. 1997. Reduced progression of atherosclerosis in apolipoprotein E-deficient mice following consumption of red wine, or its polyphenols quercetin or catechin, is associated with reduced susceptibility of LDL to oxidation and aggregation. Arterioscler Thromb Vasc Biol 17: 2744-2752. (Pubitemid 28016017)
    • (1997) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.17 , Issue.11 , pp. 2744-2752
    • Hayek, T.1    Fuhrman, B.2    Vaya, J.3    Rosenblat, M.4    Belinky, P.5    Coleman, R.6    Elis, A.7    Aviram, M.8
  • 28
    • 33846113313 scopus 로고    scopus 로고
    • Effects of fenofibrate and xuezhikang on high-fat diet-induced non-alcoholic fatty liver disease
    • DOI 10.1111/j.1440-1681.2007.04547.x
    • Hong XZ, Li LD, Wu LM,. 2007. Effects of fenofibrate and Xuezhikang on high-fat diet-induced non-alcoholic fatty liver disease. Clin Exp Pharmacol Physiol 34: 27-35. (Pubitemid 46069582)
    • (2007) Clinical and Experimental Pharmacology and Physiology , vol.34 , Issue.1-2 , pp. 27-35
    • Hong, X.Z.1    Li, L.D.2    Wu, L.M.3
  • 29
    • 0032587240 scopus 로고    scopus 로고
    • The role of TNFα and TNF receptors in obesity and insulin resistance
    • DOI 10.1046/j.1365-2796.1999.00490.x
    • Hotamisligil GS,. 1999. The role of TNFalpha and TNF receptors in obesity and insulin resistance. J Intern Med 245: 621-625. (Pubitemid 29278870)
    • (1999) Journal of Internal Medicine , vol.245 , Issue.6 , pp. 621-625
    • Hotamisligil, G.S.1
  • 30
    • 0033562693 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: Another disease of affluence
    • DOI 10.1016/S0140-6736(99)00163-4
    • James O, Day C,. 1999. Non-alcoholic steatohepatitis: another disease of affluence. Lancet 353: 1634-1636. (Pubitemid 29224514)
    • (1999) Lancet , vol.353 , Issue.9165 , pp. 1634-1636
    • James, O.1    Day, C.2
  • 32
    • 0042265627 scopus 로고    scopus 로고
    • Cytokines and NASH: A pilot study of the effects of lifestyle modification and vitamin E
    • DOI 10.1053/jhep.2003.50316
    • Kugelmas M, Hill DB, Vivian B, Marsano L, McClain CJ,. 2003. Cytokines and NASH: a pilot study of the effects of lifestyle modification and vitamin E. Hepatology 38: 413-419. (Pubitemid 36919862)
    • (2003) Hepatology , vol.38 , Issue.2 , pp. 413-419
    • Kugelmas, M.1    Hill, D.B.2    Vivian, B.3    Marsano, L.4    McClain, C.J.5
  • 35
    • 0032773482 scopus 로고    scopus 로고
    • Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro
    • DOI 10.1016/S0021-9150(99)00115-X, PII S002191509900115X
    • Mazur A, Bayle D, Lab C, Rock E, Rayssiguier Y,. 1999. Inhibitory effect of procyanidin-rich extracts on LDL oxidation in vitro. Atherosclerosis 145: 421-422. (Pubitemid 29359154)
    • (1999) Atherosclerosis , vol.145 , Issue.2 , pp. 421-422
    • Mazur, A.1    Bayle, D.2    Lab, C.3    Rock, E.4    Rayssiguier, Y.5
  • 36
    • 4344628555 scopus 로고    scopus 로고
    • The clinical features, diagnosis and natural history of nonalcoholic fatty liver disease
    • DOI 10.1016/j.cld.2004.04.004, PII S1089326104000340
    • McCullough AJ,. 2004. The clinical features, diagnosis and natural history of nonalcoholic fatty liver disease. Clin Liver Dis 8: 521-533, viii. (Pubitemid 39141140)
    • (2004) Clinics in Liver Disease , vol.8 , Issue.3 , pp. 521-533
    • McCullough, A.J.1
  • 37
    • 0032860678 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain disorders and the liver
    • DOI 10.1111/j.1478-3231.1999.tb00063.x
    • Morris AA,. 1999. Mitochondrial respiratory chain disorders and the liver. Liver 19: 357-368. (Pubitemid 29457212)
    • (1999) Liver , vol.19 , Issue.5 , pp. 357-368
    • Morris, A.A.M.1
  • 40
    • 0038644536 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
    • DOI 10.1053/jhep.2003.50193
    • Neuschwander-Tetri BA, Caldwell SH,. 2003. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology 37: 1202-1219. (Pubitemid 36538699)
    • (2003) Hepatology , vol.37 , Issue.5 , pp. 1202-1219
    • Neuschwander-Tetri, B.A.1    Caldwell, S.H.2
  • 42
    • 77954881744 scopus 로고    scopus 로고
    • Preventive effects of chronic exogenous growth hormone levels on diet-induced hepatic steatosis in rats
    • Qin Y, Tian YP,. 2010. Preventive effects of chronic exogenous growth hormone levels on diet-induced hepatic steatosis in rats. Lipids Health Dis 9: 78.
    • (2010) Lipids Health Dis , vol.9 , pp. 78
    • Qin, Y.1    Tian, Y.P.2
  • 43
    • 0034748682 scopus 로고    scopus 로고
    • Correlation of abdominal fat accumulation and liver steatosis: Importance of ultrasonographic and anthropometric measurements
    • DOI 10.1016/S0929-8266(01)00153-7, PII S0929826601001537
    • Sabir N, Sermez Y, Kazil S, Zencir M,. 2001. Correlation of abdominal fat accumulation and liver steatosis: importance of ultrasonographic and anthropometric measurements. Eur J Ultrasound 14: 121-128. (Pubitemid 33026505)
    • (2001) European Journal of Ultrasound , vol.14 , Issue.2-3 , pp. 121-128
    • Sabir, N.1    Sermez, Y.2    Kazil, S.3    Zencir, M.4
  • 44
    • 44849131936 scopus 로고    scopus 로고
    • Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase
    • DOI 10.1111/j.1745-7254.2008.00807.x
    • Shang J, Chen LL, Xiao FX, Sun H, Ding HC, Xiao H,. 2008. Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase. Acta Pharmacol Sin 29: 698-706. (Pubitemid 351799479)
    • (2008) Acta Pharmacologica Sinica , vol.29 , Issue.6 , pp. 698-706
    • Shang, J.1    Chen, L.-L.2    Xiao, F.-X.3    Sun, H.4    Ding, H.-C.5    Xiao, H.6
  • 46
    • 77956266803 scopus 로고    scopus 로고
    • Prevalence of non-alcoholic fatty liver disease and its association with cardiovascular disease in patients with type 1 diabetes
    • Targher G, Bertolini L, Padovani R, Rodella S, Zoppini G, Pichiri I, Sorgato C, Zenari L, Bonora E,. 2010. Prevalence of non-alcoholic fatty liver disease and its association with cardiovascular disease in patients with type 1 diabetes. J Hepatol 53: 713-718.
    • (2010) J Hepatol , vol.53 , pp. 713-718
    • Targher, G.1    Bertolini, L.2    Padovani, R.3    Rodella, S.4    Zoppini, G.5    Pichiri, I.6    Sorgato, C.7    Zenari, L.8    Bonora, E.9
  • 48
    • 0035125052 scopus 로고    scopus 로고
    • The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor α in the pathogenesis of non-alcoholic steatohepatitis
    • DOI 10.1136/gut.48.2.206
    • Wigg AJ, Roberts-Thomson IC, Dymock RB, McCarthy PJ, Grose RH, Cummins AG,. 2001. The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis. Gut 48: 206-211. (Pubitemid 32141844)
    • (2001) Gut , vol.48 , Issue.2 , pp. 206-211
    • Wigg, A.J.1    Roberts-Thomson, I.C.2    Dymock, R.B.3    McCarthy, P.J.4    Grose, R.H.5    Cummins, A.G.6
  • 49
    • 34250840799 scopus 로고    scopus 로고
    • Hepatic tumor necrosis factor signaling and nuclear factor-κB: Effects on liver homeostasis and beyond
    • DOI 10.1210/er.2006-0031
    • Wullaert A, van Loo G, Heyninck K, Beyaert R,. 2007. Hepatic tumor necrosis factor signaling and nuclear factor-kappaB: effects on liver homeostasis and beyond. Endocr Rev 28: 365-386. (Pubitemid 46984825)
    • (2007) Endocrine Reviews , vol.28 , Issue.4 , pp. 365-386
    • Wullaert, A.1    Van Loo, G.2    Heyninck, K.3    Beyaert, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.