메뉴 건너뛰기




Volumn 215, Issue 4, 2012, Pages 534-545

Heparin-binding epidermal growth factor-like growth factor and mesenchymal stem cells act synergistically to prevent experimental necrotizing enterocolitis

Author keywords

4,6 Diamidino 2 Phenylindole Dihydrochloride; D MEM; DAPI; Dulbecco's Modified Eagle Medium; FD; fluorescein isothiocyanate (FITC) labeled dextran; HB EGF; heparin binding epidermal growth factor like growth factor; intraperitoneal; IP; mesenchymal stem cells; MSC; NEC; necrotizing enterocolitis; yellow fluorescent protein; YFP

Indexed keywords

HEPARIN BINDING EPIDERMAL GROWTH FACTOR;

EID: 84866361378     PISSN: 10727515     EISSN: 18791190     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2012.05.037     Document Type: Article
Times cited : (57)

References (52)
  • 2
    • 0344873219 scopus 로고    scopus 로고
    • Treatment and prevention of necrotizing enterocolitis
    • J.S. Lee, R.A. Polin Treatment and prevention of necrotizing enterocolitis Semin Neonatol 8 2003 449 459
    • (2003) Semin Neonatol , vol.8 , pp. 449-459
    • Lee, J.S.1    Polin, R.A.2
  • 3
    • 0025501811 scopus 로고
    • Isolation and characterization of a macrophage-derived heparin-binding growth factor
    • G. Besner, S. Higashiyama, M. Klagsbrun Isolation and characterization of a macrophage-derived heparin-binding growth factor Cell Regul 1 1990 811 819
    • (1990) Cell Regul , vol.1 , pp. 811-819
    • Besner, G.1    Higashiyama, S.2    Klagsbrun, M.3
  • 4
    • 30344481970 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor decreases the incidence of necrotizing enterocolitis in neonatal rats
    • discussion 144-149
    • J. Feng, O.N. El-Assal, G.E. Besner Heparin-binding epidermal growth factor-like growth factor decreases the incidence of necrotizing enterocolitis in neonatal rats J Pediatr Surg 41 2006 144 149 discussion 144-149
    • (2006) J Pediatr Surg , vol.41 , pp. 144-149
    • Feng, J.1    El-Assal, O.N.2    Besner, G.E.3
  • 5
    • 23444439935 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor (HB-EGF) and necrotizing enterocolitis
    • J. Feng, O.N. El-Assal, G.E. Besner Heparin-binding EGF-like growth factor (HB-EGF) and necrotizing enterocolitis Semin Pediatr Surg 14 2005 167 174
    • (2005) Semin Pediatr Surg , vol.14 , pp. 167-174
    • Feng, J.1    El-Assal, O.N.2    Besner, G.E.3
  • 6
    • 33645280594 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor reduces intestinal apoptosis in neonatal rats with necrotizing enterocolitis
    • discussion 742-747
    • J. Feng, O.N. El-Assal, G.E. Besner Heparin-binding epidermal growth factor-like growth factor reduces intestinal apoptosis in neonatal rats with necrotizing enterocolitis J Pediatr Surg 41 2006 742 747 discussion 742-747
    • (2006) J Pediatr Surg , vol.41 , pp. 742-747
    • Feng, J.1    El-Assal, O.N.2    Besner, G.E.3
  • 7
    • 33845927363 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor promotes enterocyte migration and proliferation in neonatal rats with necrotizing enterocolitis
    • J. Feng, G.E. Besner Heparin-binding epidermal growth factor-like growth factor promotes enterocyte migration and proliferation in neonatal rats with necrotizing enterocolitis J Pediatr Surg 42 2007 214 220
    • (2007) J Pediatr Surg , vol.42 , pp. 214-220
    • Feng, J.1    Besner, G.E.2
  • 8
    • 67649362213 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor increases intestinal microvascular blood flow in necrotizing enterocolitis
    • X. Yu, A. Radulescu, N. Zorko, G.E. Besner Heparin-binding EGF-like growth factor increases intestinal microvascular blood flow in necrotizing enterocolitis Gastroenterology 137 2009 221 230
    • (2009) Gastroenterology , vol.137 , pp. 221-230
    • Yu, X.1    Radulescu, A.2    Zorko, N.3    Besner, G.E.4
  • 9
    • 84863229817 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor protects intestinal stem cells from injury in a rat model of necrotizing enterocolitis
    • C.L. Chen, X. Yu, I.O. James Heparin-binding EGF-like growth factor protects intestinal stem cells from injury in a rat model of necrotizing enterocolitis Lab Invest 92 2012 331 344
    • (2012) Lab Invest , vol.92 , pp. 331-344
    • Chen, C.L.1    Yu, X.2    James, I.O.3
  • 10
    • 77957766222 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor overexpression in transgenic mice increases resistance to necrotizing enterocolitis
    • A. Radulescu, H.Y. Zhang, X. Yu Heparin-binding epidermal growth factor-like growth factor overexpression in transgenic mice increases resistance to necrotizing enterocolitis J Pediatr Surg 45 2010 1933 1939
    • (2010) J Pediatr Surg , vol.45 , pp. 1933-1939
    • Radulescu, A.1    Zhang, H.Y.2    Yu, X.3
  • 11
    • 77950485280 scopus 로고    scopus 로고
    • Deletion of the heparin-binding epidermal growth factor-like growth factor gene increases susceptibility to necrotizing enterocolitis
    • A. Radulescu, X. Yu, N.D. Orvets Deletion of the heparin-binding epidermal growth factor-like growth factor gene increases susceptibility to necrotizing enterocolitis J Pediatr Surg 45 2010 729 734
    • (2010) J Pediatr Surg , vol.45 , pp. 729-734
    • Radulescu, A.1    Yu, X.2    Orvets, N.D.3
  • 12
    • 0033404844 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor protects rat intestine from ischemia/reperfusion injury
    • S.B. Pillai, C.E. Hinman, M.H. Luquette Heparin-binding epidermal growth factor-like growth factor protects rat intestine from ischemia/reperfusion injury J Surg Res 87 1999 225 231
    • (1999) J Surg Res , vol.87 , pp. 225-231
    • Pillai, S.B.1    Hinman, C.E.2    Luquette, M.H.3
  • 13
    • 0035212794 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor decreases inducible nitric oxide synthase and nitric oxide production after intestinal ischemia/reperfusion injury
    • G. Xia, M. Lara-Marquez, M.H. Luquette Heparin-binding EGF-like growth factor decreases inducible nitric oxide synthase and nitric oxide production after intestinal ischemia/reperfusion injury Antioxid Redox Signal 3 2001 919 930
    • (2001) Antioxid Redox Signal , vol.3 , pp. 919-930
    • Xia, G.1    Lara-Marquez, M.2    Luquette, M.H.3
  • 14
    • 0036307231 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor preserves crypt cell proliferation and decreases bacterial translocation after intestinal ischemia/reperfusion injury
    • discussion 1081-1087
    • G. Xia, A.E. Martin, M.P. Michalsky, G.E. Besner Heparin-binding EGF-like growth factor preserves crypt cell proliferation and decreases bacterial translocation after intestinal ischemia/reperfusion injury J Pediatr Surg 37 2002 1081 1087 discussion 1081-1087
    • (2002) J Pediatr Surg , vol.37 , pp. 1081-1087
    • Xia, G.1    Martin, A.E.2    Michalsky, M.P.3    Besner, G.E.4
  • 15
    • 0037370330 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor downregulates expression of adhesion molecules and infiltration of inflammatory cells after intestinal ischemia/reperfusion injury
    • G. Xia, A.E. Martin, G.E. Besner Heparin-binding EGF-like growth factor downregulates expression of adhesion molecules and infiltration of inflammatory cells after intestinal ischemia/reperfusion injury J Pediatr Surg 38 2003 434 439
    • (2003) J Pediatr Surg , vol.38 , pp. 434-439
    • Xia, G.1    Martin, A.E.2    Besner, G.E.3
  • 16
    • 0038324579 scopus 로고    scopus 로고
    • Upregulation of endogenous heparin-binding EGF-like growth factor (HB-EGF) expression after intestinal ischemia/reperfusion injury
    • G. Xia, A.W. Rachfal, A.E. Martin, G.E. Besner Upregulation of endogenous heparin-binding EGF-like growth factor (HB-EGF) expression after intestinal ischemia/reperfusion injury J Invest Surg 16 2003 57 63
    • (2003) J Invest Surg , vol.16 , pp. 57-63
    • Xia, G.1    Rachfal, A.W.2    Martin, A.E.3    Besner, G.E.4
  • 17
    • 1242298520 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor and intestinal ischemia-reperfusion injury
    • O.N. El-Assal, G.E. Besner Heparin-binding epidermal growth factor-like growth factor and intestinal ischemia-reperfusion injury Semin Pediatr Surg 13 2004 2 10
    • (2004) Semin Pediatr Surg , vol.13 , pp. 2-10
    • El-Assal, O.N.1    Besner, G.E.2
  • 18
    • 23244468565 scopus 로고    scopus 로고
    • HB-EGF enhances restitution after intestinal ischemia/reperfusion via PI3K/Akt and MEK/ERK1/2 activation
    • O.N. El-Assal, G.E. Besner HB-EGF enhances restitution after intestinal ischemia/reperfusion via PI3K/Akt and MEK/ERK1/2 activation Gastroenterology 129 2005 609 625
    • (2005) Gastroenterology , vol.129 , pp. 609-625
    • El-Assal, O.N.1    Besner, G.E.2
  • 19
    • 34047250151 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor decreases inflammatory cytokine expression after intestinal ischemia/reperfusion injury
    • D.V. Rocourt, V.B. Mehta, G.E. Besner Heparin-binding EGF-like growth factor decreases inflammatory cytokine expression after intestinal ischemia/reperfusion injury J Surg Res 139 2007 269 273
    • (2007) J Surg Res , vol.139 , pp. 269-273
    • Rocourt, D.V.1    Mehta, V.B.2    Besner, G.E.3
  • 20
    • 44949244211 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor gene disruption is associated with delayed intestinal restitution, impaired angiogenesis, and poor survival after intestinal ischemia in mice
    • O.N. El-Assal, H. Paddock, A. Marquez, G.E. Besner Heparin-binding epidermal growth factor-like growth factor gene disruption is associated with delayed intestinal restitution, impaired angiogenesis, and poor survival after intestinal ischemia in mice J Pediatr Surg 43 2008 1182 1190
    • (2008) J Pediatr Surg , vol.43 , pp. 1182-1190
    • El-Assal, O.N.1    Paddock, H.2    Marquez, A.3    Besner, G.E.4
  • 21
    • 82955240979 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor protects pericytes from injury
    • X. Yu, A. Radulescu, C.L. Chen Heparin-binding EGF-like growth factor protects pericytes from injury J Surg Res 172 2012 165 176
    • (2012) J Surg Res , vol.172 , pp. 165-176
    • Yu, X.1    Radulescu, A.2    Chen, C.L.3
  • 22
    • 34547588249 scopus 로고    scopus 로고
    • Heparin-binding EGF-like growth factor preserves mesenteric microcirculatory blood flow and protects against intestinal injury in rats subjected to hemorrhagic shock and resuscitation
    • O.N. El-Assal, A. Radulescu, G.E. Besner Heparin-binding EGF-like growth factor preserves mesenteric microcirculatory blood flow and protects against intestinal injury in rats subjected to hemorrhagic shock and resuscitation Surgery 142 2007 234 242
    • (2007) Surgery , vol.142 , pp. 234-242
    • El-Assal, O.N.1    Radulescu, A.2    Besner, G.E.3
  • 23
    • 67650566649 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor is essential for preservation of gut barrier function after hemorrhagic shock and resuscitation in mice
    • H.Y. Zhang, A. Radulescu, G.E. Besner Heparin-binding epidermal growth factor-like growth factor is essential for preservation of gut barrier function after hemorrhagic shock and resuscitation in mice Surgery 146 2009 334 339
    • (2009) Surgery , vol.146 , pp. 334-339
    • Zhang, H.Y.1    Radulescu, A.2    Besner, G.E.3
  • 24
    • 84858438663 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor (HB-EGF) preserves gut barrier function by blocking neutrophil-endothelial cell adhesion after hemorrhagic shock and resuscitation in mice
    • H.Y. Zhang, I. James, C.L. Chen, G.E. Besner Heparin-binding epidermal growth factor-like growth factor (HB-EGF) preserves gut barrier function by blocking neutrophil-endothelial cell adhesion after hemorrhagic shock and resuscitation in mice Surgery 151 2012 594 605
    • (2012) Surgery , vol.151 , pp. 594-605
    • Zhang, H.Y.1    James, I.2    Chen, C.L.3    Besner, G.E.4
  • 25
    • 78751581633 scopus 로고    scopus 로고
    • Mice overexpressing the gene for heparin-binding epidermal growth factor-like growth factor (HB-EGF) have increased resistance to hemorrhagic shock and resuscitation
    • H.Y. Zhang, A. Radulescu, C.L. Chen Mice overexpressing the gene for heparin-binding epidermal growth factor-like growth factor (HB-EGF) have increased resistance to hemorrhagic shock and resuscitation Surgery 149 2011 276 283
    • (2011) Surgery , vol.149 , pp. 276-283
    • Zhang, H.Y.1    Radulescu, A.2    Chen, C.L.3
  • 26
    • 80054706802 scopus 로고    scopus 로고
    • HB-EGF improves intestinal microcirculation after hemorrhagic shock
    • H.Y. Zhang, A. Radulescu, Y. Chen, G.E. Besner HB-EGF improves intestinal microcirculation after hemorrhagic shock J Surg Res 171 2011 218 225
    • (2011) J Surg Res , vol.171 , pp. 218-225
    • Zhang, H.Y.1    Radulescu, A.2    Chen, Y.3    Besner, G.E.4
  • 27
    • 77952243854 scopus 로고    scopus 로고
    • Mesenchymal stem cells improve small intestinal integrity through regulation of endogenous epithelial cell homeostasis
    • A. Semont, M. Mouiseddine, A. Francois Mesenchymal stem cells improve small intestinal integrity through regulation of endogenous epithelial cell homeostasis Cell Death Differ 17 2010 952 961
    • (2010) Cell Death Differ , vol.17 , pp. 952-961
    • Semont, A.1    Mouiseddine, M.2    Francois, A.3
  • 28
    • 77049119928 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells to prevent radiation-induced intestinal injury in mice
    • K. Kudo, Y. Liu, K. Takahashi Transplantation of mesenchymal stem cells to prevent radiation-induced intestinal injury in mice J Radiat Res (Tokyo) 51 2010 73 79
    • (2010) J Radiat Res (Tokyo) , vol.51 , pp. 73-79
    • Kudo, K.1    Liu, Y.2    Takahashi, K.3
  • 29
    • 78650179897 scopus 로고    scopus 로고
    • Electro-acupuncture promotes differentiation of mesenchymal stem cells, regeneration of nerve fibers and partial functional recovery after spinal cord injury
    • Q. Yan, J.W. Ruan, Y. Ding Electro-acupuncture promotes differentiation of mesenchymal stem cells, regeneration of nerve fibers and partial functional recovery after spinal cord injury Exp Toxicol Pathol 63 2011 151 156
    • (2011) Exp Toxicol Pathol , vol.63 , pp. 151-156
    • Yan, Q.1    Ruan, J.W.2    Ding, Y.3
  • 30
    • 36448952268 scopus 로고    scopus 로고
    • Differentiation of human mesenchymal stem cells into mesangial cells in post-glomerular injury murine model
    • C.Y. Wong, S.K. Cheong, P.L. Mok, C.F. Leong Differentiation of human mesenchymal stem cells into mesangial cells in post-glomerular injury murine model Pathology 40 2008 52 57
    • (2008) Pathology , vol.40 , pp. 52-57
    • Wong, C.Y.1    Cheong, S.K.2    Mok, P.L.3    Leong, C.F.4
  • 31
    • 78651318022 scopus 로고    scopus 로고
    • Paracrine effects of mesenchymal stem cells in cisplatin-induced renal injury require heme oxygenase-1
    • A. Zarjou, J. Kim, A.M. Traylor Paracrine effects of mesenchymal stem cells in cisplatin-induced renal injury require heme oxygenase-1 Am J Physiol Renal Physiol 300 2011 F254 F262
    • (2011) Am J Physiol Renal Physiol , vol.300
    • Zarjou, A.1    Kim, J.2    Traylor, A.M.3
  • 32
    • 67650531456 scopus 로고    scopus 로고
    • Mesenchymal stem cells enhance the viability and proliferation of human fetal intestinal epithelial cells following hypoxic injury via paracrine mechanisms
    • B.R. Weil, T.A. Markel, J.L. Herrmann Mesenchymal stem cells enhance the viability and proliferation of human fetal intestinal epithelial cells following hypoxic injury via paracrine mechanisms Surgery 146 2009 190 197
    • (2009) Surgery , vol.146 , pp. 190-197
    • Weil, B.R.1    Markel, T.A.2    Herrmann, J.L.3
  • 33
    • 80053912340 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy in necrotizing enterocolitis: A rat study
    • C. Tayman, D. Uckan, E. Kilic Mesenchymal stem cell therapy in necrotizing enterocolitis: a rat study Pediatr Res 70 2011 489 494
    • (2011) Pediatr Res , vol.70 , pp. 489-494
    • Tayman, C.1    Uckan, D.2    Kilic, E.3
  • 34
    • 33746216924 scopus 로고    scopus 로고
    • Murine mesenchymal stem cells transplanted to the central nervous system of neonatal versus adult mice exhibit distinct engraftment kinetics and express receptors that guide neuronal cell migration
    • D.G. Phinney, M. Baddoo, M. Dutreil Murine mesenchymal stem cells transplanted to the central nervous system of neonatal versus adult mice exhibit distinct engraftment kinetics and express receptors that guide neuronal cell migration Stem Cells Dev 15 2006 437 447
    • (2006) Stem Cells Dev , vol.15 , pp. 437-447
    • Phinney, D.G.1    Baddoo, M.2    Dutreil, M.3
  • 35
    • 84855839268 scopus 로고    scopus 로고
    • Fetal liver-derived mesenchymal stem cell engraftment after allogeneic in utero transplantation into rabbits
    • R. Moreno, I. Martinez-Gonzalez, M. Rosal Fetal liver-derived mesenchymal stem cell engraftment after allogeneic in utero transplantation into rabbits Stem Cells Dev 21 2012 284 295
    • (2012) Stem Cells Dev , vol.21 , pp. 284-295
    • Moreno, R.1    Martinez-Gonzalez, I.2    Rosal, M.3
  • 36
    • 77954954424 scopus 로고    scopus 로고
    • Cell therapy of congenital corneal diseases with umbilical mesenchymal stem cells: Lumican null mice
    • H. Liu, J. Zhang, C.Y. Liu Cell therapy of congenital corneal diseases with umbilical mesenchymal stem cells: lumican null mice PLoS One 5 2010 e10707
    • (2010) PLoS One , vol.5 , pp. 10707
    • Liu, H.1    Zhang, J.2    Liu, C.Y.3
  • 37
    • 84866355018 scopus 로고    scopus 로고
    • A technique for systemic mesenchymal stem cell transplantation in newborn rat pups
    • 10.3109/08941939.2012.661519 In press
    • J. Yang, D. Watkins, C.L. Chen A technique for systemic mesenchymal stem cell transplantation in newborn rat pups J Invest Surg 2012 10.3109/08941939. 2012.661519 In press
    • (2012) J Invest Surg
    • Yang, J.1    Watkins, D.2    Chen, C.L.3
  • 38
    • 34547567884 scopus 로고    scopus 로고
    • The participation of mesenchymal stem cells in tumor stroma formation and their application as targeted-gene delivery vehicles
    • B. Hall, M. Andreeff, F. Marini The participation of mesenchymal stem cells in tumor stroma formation and their application as targeted-gene delivery vehicles Handb Exp Pharmacol 2007 263 283
    • (2007) Handb Exp Pharmacol , pp. 263-283
    • Hall, B.1    Andreeff, M.2    Marini, F.3
  • 39
    • 0016294579 scopus 로고
    • An experimental study of acute neonatal enterocolitis-the importance of breast milk
    • B. Barlow, T.V. Santulli, W.C. Heird An experimental study of acute neonatal enterocolitis-the importance of breast milk J Pediatr Surg 9 1974 587 595
    • (1974) J Pediatr Surg , vol.9 , pp. 587-595
    • Barlow, B.1    Santulli, T.V.2    Heird, W.C.3
  • 40
    • 0028020174 scopus 로고
    • Role of asphyxia and feeding in a neonatal rat model of necrotizing enterocolitis
    • M.S. Caplan, E. Hedlund, L. Adler, W. Hsueh Role of asphyxia and feeding in a neonatal rat model of necrotizing enterocolitis Pediatr Pathol 14 1994 1017 1028
    • (1994) Pediatr Pathol , vol.14 , pp. 1017-1028
    • Caplan, M.S.1    Hedlund, E.2    Adler, L.3    Hsueh, W.4
  • 41
    • 33847612451 scopus 로고    scopus 로고
    • Comprehensive analysis of chemotactic factors for bone marrow mesenchymal stem cells
    • Y. Ozaki, M. Nishimura, K. Sekiya Comprehensive analysis of chemotactic factors for bone marrow mesenchymal stem cells Stem Cells Dev 16 2007 119 129
    • (2007) Stem Cells Dev , vol.16 , pp. 119-129
    • Ozaki, Y.1    Nishimura, M.2    Sekiya, K.3
  • 42
    • 77951188870 scopus 로고    scopus 로고
    • Mesenchymal stem cell-based therapy: A new paradigm in regenerative medicine
    • N.K. Satija, V.K. Singh, Y.K. Verma Mesenchymal stem cell-based therapy: a new paradigm in regenerative medicine J Cell Mol Med 13 2009 4385 4402
    • (2009) J Cell Mol Med , vol.13 , pp. 4385-4402
    • Satija, N.K.1    Singh, V.K.2    Verma, Y.K.3
  • 44
    • 84860234771 scopus 로고    scopus 로고
    • Recent progress toward understanding the physiological function of bone marrow mesenchymal stem cells
    • C. Shi Recent progress toward understanding the physiological function of bone marrow mesenchymal stem cells Immunology 136 2012 133 138
    • (2012) Immunology , vol.136 , pp. 133-138
    • Shi, C.1
  • 45
    • 77949435377 scopus 로고    scopus 로고
    • Intestinal phenotype in mice overexpressing a heparin-binding EGF-like growth factor transgene in enterocytes
    • C.L. Chen, V.B. Metha, H.Y. Zhang Intestinal phenotype in mice overexpressing a heparin-binding EGF-like growth factor transgene in enterocytes Growth factors 28 2010 82 97
    • (2010) Growth Factors , vol.28 , pp. 82-97
    • Chen, C.L.1    Metha, V.B.2    Zhang, H.Y.3
  • 46
    • 79960844090 scopus 로고    scopus 로고
    • Intracoronary mesenchymal stem cells promote postischemic myocardial functional recovery, decrease inflammation, and reduce apoptosis via a signal transducer and activator of transcription 3 mechanism
    • J.A. Poynter, J.L. Herrmann, M.C. Manukyan Intracoronary mesenchymal stem cells promote postischemic myocardial functional recovery, decrease inflammation, and reduce apoptosis via a signal transducer and activator of transcription 3 mechanism J Am Coll Surg 213 2011 253 260
    • (2011) J Am Coll Surg , vol.213 , pp. 253-260
    • Poynter, J.A.1    Herrmann, J.L.2    Manukyan, M.C.3
  • 47
    • 60849112830 scopus 로고    scopus 로고
    • Intravenous administration of mesenchymal stem cells genetically modified with extracellular superoxide dismutase improves survival in irradiated mice
    • A.S. Abdel-Mageed, A.J. Senagore, D.W. Pietryga Intravenous administration of mesenchymal stem cells genetically modified with extracellular superoxide dismutase improves survival in irradiated mice Blood 113 2009 1201 1203
    • (2009) Blood , vol.113 , pp. 1201-1203
    • Abdel-Mageed, A.S.1    Senagore, A.J.2    Pietryga, D.W.3
  • 48
    • 67649171661 scopus 로고    scopus 로고
    • Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6
    • R.H. Lee, A.A. Pulin, M.J. Seo Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6 Cell Stem Cell 5 2009 54 63
    • (2009) Cell Stem Cell , vol.5 , pp. 54-63
    • Lee, R.H.1    Pulin, A.A.2    Seo, M.J.3
  • 49
    • 0028881201 scopus 로고
    • Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): Implications for therapeutic use
    • H.M. Lazarus, S.E. Haynesworth, S.L. Gerson Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use Bone Marrow Transplant 16 1995 557 564
    • (1995) Bone Marrow Transplant , vol.16 , pp. 557-564
    • Lazarus, H.M.1    Haynesworth, S.E.2    Gerson, S.L.3
  • 50
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: A phase II study
    • K. Le Blanc, F. Frassoni, L. Ball Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study Lancet 371 2008 1579 1586
    • (2008) Lancet , vol.371 , pp. 1579-1586
    • Le Blanc, K.1    Frassoni, F.2    Ball, L.3
  • 51
    • 79958770457 scopus 로고    scopus 로고
    • Effective treatment of severe steroid-resistant acute graft-versus-host disease with umbilical cord-derived mesenchymal stem cells
    • K.H. Wu, C.K. Chan, C. Tsai Effective treatment of severe steroid-resistant acute graft-versus-host disease with umbilical cord-derived mesenchymal stem cells Transplantation 91 2011 1412 1416
    • (2011) Transplantation , vol.91 , pp. 1412-1416
    • Wu, K.H.1    Chan, C.K.2    Tsai, C.3
  • 52
    • 0344585432 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B activation and its target genes by heparin-binding epidermal growth factor-like growth factor
    • V.B. Mehta, G.E. Besner Inhibition of NF-kappa B activation and its target genes by heparin-binding epidermal growth factor-like growth factor J Immunol 171 2003 6014 6022
    • (2003) J Immunol , vol.171 , pp. 6014-6022
    • Mehta, V.B.1    Besner, G.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.