Cell therapy of congenital corneal diseases with umbilical mesenchymal stem cells: Lumican null mice

PLoS ONE

Volumn 5, Issue 5, 2010, Pages

  Liu, Hongshan ^a   Zhang, Jianhua ^a   Liu, Chia Yang ^a   Wang, I Jong ^b   Sieber, Martin ^c   Chang, John ^c   Jester, James V ^d   Kao, Winston W Y ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c Bionet Corp   (Taiwan)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; BIOLOGICAL MARKER; CD34 ANTIGEN; KERATOCAN; LUMICAN; ALDH3A1PROTEIN, MOUSE; COLLAGEN; KERA PROTEIN, MOUSE; KERATAN SULFATE; PROTEOCHONDROITIN SULFATE; PROTEOGLYCAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL ISOLATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CONGENITAL DISORDER; CONTROLLED STUDY; CORD BLOOD STEM CELL TRANSPLANTATION; CORNEA DISEASE; CORNEA OPACITY; CORNEA STROMA; CORNEA THICKNESS; DENDRITIC CELL; EXPERIMENTAL MODEL; GRAFT REJECTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LAMELLAR BODY; LIGHT SCATTERING; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; NEWBORN; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; THERAPY EFFECT; ANIMAL; APOPTOSIS; CELL SEPARATION; CELL SHAPE; CORNEA; CYTOLOGY; FLOW CYTOMETRY; METABOLISM; PATHOLOGY; STROMA CELL; TRANSPLANTATION; UMBILICAL CORD; UPREGULATION;

MUS;

ALDEHYDE DEHYDROGENASE; ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CELL PROLIFERATION; CELL SEPARATION; CELL SHAPE; CELL SURVIVAL; COLLAGEN; CORNEA; CORNEAL DISEASES; DENDRITIC CELLS; FLOW CYTOMETRY; HUMANS; KERATAN SULFATE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MICE; PROTEOCHONDROITIN SULFATES; PROTEOGLYCANS; STROMAL CELLS; UMBILICAL CORD; UP-REGULATION;

EID: 77954954424     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010707     Document Type: Article

References (54)

1. Darabi R, Gehlbach K, Bachoo RM, Kamath S, Osawa M, et al. (2008) Functional skeletal muscle regeneration from differentiating embryonic stem cells. Nature Medicine 14: 134-143.
2. Fraidenraich D, Stillwell E, Romero E, Wilkes D, Manova K, et al. (2004) Rescue of cardiac defects in Id knockout embryos by injection of embryonic stem cells. Science 306: 247-252.
3. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, et al. (2001) Bone marrow cells regenerate infarcted myocardium. Nature 410: 701-705.
4. Brazelton TR, Rossi FMV, Keshet GI, Blau HM (2000) From marrow to brain: expression of neuronal phenotypes in adult mice. Science 290: 1775-1779.
5. Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keenek CD, et al. (2002) Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418: 41-49.
6. Lee J, Jeyakumar M, Gonzalez R, Takahashi H, Lee P, et al. (2007) Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease. Nature Medicine 13: 439-447.
7. Zakrzewski JL, Kochman AA, Lu SX, Terwey TH, Kim TD, et al. (2006) Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation. Nature Medicine 12: 1039-1047.
8. Camargo FD, Green R, Capetenaki Y, Jackson KA, Goodell MA (2003) Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates. Nature Medicine 9: 1520-1527.
9. Miyahara Y, Nagaya N, Kataoka M, Yanagawa B, Tanaka K, et al. (2006) Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction. Nature Medicine 12: 459-465.
10. Aurich I, Mueller LP, Aurich H, Luetzkendorf J, Tisljar K, et al. (2007) Functional integration of hepatocytes derived from human mesenchymal stem cells into mouse livers. Gut 56: 405-415.
11. Prockop DJ (1997) Marrow stromal cells as stem cells for non-hematopoietic tissues. Science 276: 71-74.
12. Haniffa MA, Collin MP, Buckley CD, Dazzi F (2009) Mesenchymal stem cells: the fibroblasts' new clothes? Haematologica 94: 258-263.
13. Mobasheri A, Csaki C, Clutterbuck AL, Rahmanzadeh M, Shakibaei M (2009) Mesenchymal stem cells in connective tissue engineering and regenerative medicine: applications in cartilage repair and osteoarthritis therapy. Histol Histopathol 24: 347-366.
14. Nadri S, Soleimani M, Kiani J, Atashi A, Izadpanah R (2008) Multipotent mesenchymal stem cells from adult human eye conjunctiva stromal cells. Differentiation 76: 223-231.
15. Ikehara S (2009) The future of stem cell transplantation in autoimmune disease. Clin Rev Allergy Immunol; doi July21:10.1007/s12016-009-8159-5.
16. Popp FC, Eggenhofer E, Renner P, Geissler EK, Piso P, et al. (2009) Mesenchymal stem cells can affect solid organ allograft survival. Transplantation 87: S57-62.
17. Dai LJ, Li HY, Guan LY, Ritchie G, Zhou JX (2009) The therapeutic potential of bone marrow-derived mesenchymal stem cells on hepatic cirrhosis. Stem Cell Res 2: 16-25.
18. Chhabra P, Brayman KL (2009) The use of stem cells in kidney disease. Curr Opin Organ Transplant 14: 72-78.
19. Kitada M, Dezawa M (2009) Induction system of neural and muscle lineage cells from bone marrow stromal cells; a new strategy for tissue reconstruction in degenerative diseases. Histol Histopathol 24: 631-642.
20. Lasala GP, Minguell JJ (2009) Bone marrow-derived stem/progenitor cells: their use in clinical studies for the treatment of myocardial infarction. Heart Lung Circ 18: 171-180.
21. Vaquero J, Zurita M (2009) Bone marrow stromal cells for spinal cord repair: a challenge for contemporary neurobiology. Histol Histopathol 24: 107-116.
22. D'Ippolito G, Schiller PC, Ricordi C, Roos BA, Howard GA (1999) Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow. J Bone Miner Res 14: 1115-1122.
23. Rao MS, Mattson MP (2001) Stem cells and aging; expanding the possibilities. Mech Ageing Dev 122: 713-734.
24. Tsai PC, Fu TW, Chen YM, Ko TL, Chen TH, et al. (2009) The therapeutic potential of human umbilical mesenchymal stem cells from Wharton's jelly in the treatment of rat liver fibrosis. Liver Transpl 15: 484-495.
25. Yang CC, Shih YH, Ko MH, Hsu SY, Cheng H, et al. (2008) Transplantation of Human Umbilical Mesenchymal Stem Cells from Wharton's Jelly after Complete Transection of the Rat Spinal Cord. PLoS ONE 3(10): e3336. doi:10.1371/journal.pone.0003336.
26. Wagner W, Wein F, Seckinger A, Frankhauser M, Wirkner U, et al. (2005) Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood. Exp Hematol 33: 1402-1416.
27. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglasa R, et al. Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147.
28. Moffatt SL, Cartwright VA, Stumpf TH (2005) Centennial review of corneal transplantation. Clin Experiment Ophthalmol 33: 642-657.
29. Garg P, Krishna PV, Stratis AK, Gopinathan U (2005) The value of corneal transplantation in reducing blindness. Eye 19: 1106-1114.
30. Kao WW, Funderburgh JL, Xia Y, Liu CY, Conrad GW (2006) Focus on molecules: lumican. Exp Eye Res 82: 3-4.
31. Saika S, Shiraishi A, Liu CY, Funderburgh JL, Kao CW, et al. (2000) Role of lumican in the corneal epithelium during wound healing. J Biol Chem 275: 2607-2612.
32. Chakravarti S, Magnuson T, Lass JH (1998) Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican. J Cell Biol 141: 1277-1286.
33. Kassis I, Zangi L, Rivkin R, Levdansky L, Samuel S, et al. (2006) Isolation of mesenchymal stem cells from G-CSF-mobilized human peripheral blood using fibrin microbeads. Bone Marrow Transplantation 37: 967-976.
34. Chen J, Wang C, Lü S, Wu J, Guo X, et al. (2005) In vivo chondrogenesis of adult bone-marrow-derived autologous mesenchymal stem cells. Cell Tissue Res 319: 429-438.
35. Sutherland DR, Anderson L, Keeney M, Nayar R, Chin-Yee I (1996) The ISHAGE guidelines for CD34+ cell determination by flow cytometry. International Society of Hematotherapy and Graft Engineering. J. Hematother 5: 213-226.
36. Jester JV, Ghee Lee Y, Li J, Chakravarti S, Paul J, et al. (2001) Measurement of corneal sublayer thickness and transparency in transgenic mice with altered corneal clarity using in vivo confocal microscopy. Vision Res 41: 1283-1290.
37. Chakravarti S, Petroll WM, Hassell JR, Jester JV, Lass JH, et al. (2000) Corneal opacity in lumican-null mice: defects in collagen fibril structure and packing in the posterior stroma. Invest Ophthalmol Vis Sci 41: 3365-3373.
38. Han M, Giese G, Bille JF (1991) Second harmonic generation imaging collagen fibrils in cornea and sclera. Optics Express 13: 5791-5797.
39. Morishige N, Petroll WM, Nishida T, Kenney MC, Jester JV (2006) Noninvasive corneal stromal collagen imaging using two-photon-generated second-harmonic signals. J Cataract Refract Surg 32: 1784-1791.
40. Raimondo S, Penna C, Pagliaro P, Geuna S (2006) Morphological characterization of GFP stably transfected adult mesenchymal bone marrow stem cells. J Anat 208: 3-12.
41. Nauta AJ, Fibbe WE (2007) Immunomodulatory properties of mesenchymal stromal cells. Blood 110: 3499-3506.
42. Liu CY, Birk DE, Hassel JR, Kane B, Kao WW (2003) Keratocan-deficient mice display alterations in corneal structure. J Biol Chem 278: 21672-21677.
43. Joseph A, Hossain P, Jham S, Jones RE, Tighe P, et al. (2003) Expression of CD34 and L-selectin on human corneal keratocytes. Invest Ophthalmol Vis Sci 44: 4689-4692.
44. Espana EM, Kawakita T, Liu CY, Tseng SCG (2005) CD-34 expression by cultured human keratocytes is downregulated during myofibroblast differentiation induced by TGF-b1. Invest Ophthalmol Vis Sci 45: 2985-2991.
45. Carlson EC, Liu CY, Chikama T, Hayashi Y, Kao CK, et al. (2005) Keratocan, a Cornea-specific Keratan Sulfate Proteoglycan, Is Regulated by Lumican. J Biol Chem 280: 25541-25547.
46. Carlson EC, Lin M, Liu CY, Kao WW, Perez VL, et al. (2007) Keratocan and lumican regulate neutrophil infiltration and corneal clarity in lipopolysaccharide-induced keratitis by direct interaction with CXCL1. J Biol Chem 282: 35502-35509.
47. Khan BF, Harissi-Dagher M, Khan DM, Dohlman CH (2007) Advances in Boston keratoprosthesis: enhancing retention and prevention of infection and inflammation. Int Ophthalmol Clin 47: 61-71.
48. Myung D, Duhamel PE, Cochran JR, Noolandi J, Ta CN, et al. (2008) Development of hydrogel-based keratoprostheses: a materials perspective. Biotechnol Prog 24: 735-741.
49. Du Y, Carlson EC, Funderburgh ML, Birk DE, Pearlman E, et al. (2009) Stem cell therapy restores transparency to defective murine corneas. Stem Cells 27: 1635-1642.
50. Nasef A, Ashammakhi N, Fouillard L (2008) Immunomodulatory effect of mesenchymal stromal cells: possible mechanisms. Regen Med 3: 531-546.
51. Moioli EK, Clark PA, Chen M, Dennis JE, Erickson HP, et al. (2008) Synergistic actions of hematopoietic and mesenchymal stem/progenitor cells in vascularizing bioengineered tissues. PLoS ONE 3(12): e3922. doi:10.1371/journal. pone.0003922.
52. Isaikina Y, Shman T (2008) Influence of mesenchymal stem cells derived from bone marrow of children with oncohematological diseases on proliferation and self-renewal of hematopoietic progenitor cells in vitro. Exp Oncol 30: 121-128.
53. Ren G, Zhang L, Zhao X, Xu G, Zhang Y, et al. (2008) Mesenchymal stem cellmediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2: 141-150.
54. Jester JV, Petroll WM, Cavanagh HD (1999) Measurement of tissue thickness using confocal microscopy. Methods Enzymol 307: 230-245.