The glycine reuptake inhibitor Org24598 and acamprosate reduce ethanol intake in the rat; Tolerance development to acamprosate but not to Org24598

Addiction Biology

Volumn 17, Issue 5, 2012, Pages 897-907

  Lidö, Helga H ^a   Marston, Hugh ^c   Ericson, Mia ^a   Söderpalm, Bo ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c Merck Sharp & Dohme Limited   (United Kingdom)

Author keywords

Acamprosate; dopamine; ethanol intake; glycine transporter 1 inhibitors; nucleus accumbens; rat

Indexed keywords

ACAMPROSATE; ALCOHOL; BETA ALANINE; DOPAMINE; DRUGS USED IN THE TREATMENT OF ADDICTION; GLYCINE; ORG 24598; TAURINE; UNCLASSIFIED DRUG; WATER;

ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ALCOHOLISM; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOPAMINE BLOOD LEVEL; DRINKING BEHAVIOR; DRUG EFFICACY; DRUG INJECTION VOLUME; DRUG TOLERANCE; EVOKED RESPONSE; FLUID INTAKE; IN VIVO STUDY; MALE; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; RISK REDUCTION; TREATMENT DURATION;

ALCOHOL DETERRENTS; ALCOHOL DRINKING; ANIMALS; BETA-ALANINE; DOPAMINE; DRUG TOLERANCE; GLYCINE; GLYCINE PLASMA MEMBRANE TRANSPORT PROTEINS; MALE; NUCLEUS ACCUMBENS; RATS; RATS, WISTAR; TAURINE;

EID: 84866354963     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/j.1369-1600.2011.00367.x     Document Type: Article

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