Glycine receptor expression in the forebrain of male AA/ANA rats

Brain Research

Volumn 1305, Issue , 2009, Pages

  Jonsson, Susanne ^a   Kerekes, Nora ^a   Hyytiä, Petri ^b   Ericson, Mia ^a   Söderpalm, Bo ^a,c  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Ethanol; Gene expression; Glycine receptor; qPCR; Rat

Indexed keywords

ALCOHOL DRINKING; ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; MALE; PROSENCEPHALON; RANDOM ALLOCATION; RATS; RATS, MUTANT STRAINS; RECEPTORS, GLYCINE; RNA, MESSENGER; SPECIES SPECIFICITY;

ANIMALIA; RATTUS;

EID: 71849097500     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.09.053     Document Type: Article

References (51)

1. Becker C.M., Hoch W., and Betz H. Glycine receptor heterogeneity in rat spinal cord during postnatal development. EMBO J. 7 (1988) 3717-3726
2. Betz H. Structure and function of inhibitory glycine receptors. Q. Rev. Biophys. 25 (1992) 381-394
3. Bormann J., Rundstrom N., Betz H., and Langosch D. Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers. EMBO J. 12 (1993) 3729-3737
4. Dahchour A., and De Witte P. Ethanol and amino acids in the central nervous system: assessment of the pharmacological actions of acamprosate. Prog. Neurobiol. 60 (2000) 343-362
5. Dahchour A., Quertemont E., and De Witte P. Taurine increases in the nucleus accumbens microdialysate after acute ethanol administration to naive and chronically alcoholised rats. Brain Res. 735 (1996) 9-19
6. De Witte P., Dahchour A., and Quertemont E. Acute and chronic alcohol injection increase taurine in the nucleus accumbens. Alcohol Alcohol., Suppl. 2 (1994) 229-233
7. Deleuze C., Runquist M., Orcel H., Rabie A., Dayanithi G., Alonso G., and Hussy N. Structural difference between heteromeric somatic and homomeric axonal glycine receptors in the hypothalamo-neurohypophysial system. Neuroscience 135 (2005) 475-483
8. Devaud L.L., Smith F.D., Grayson D.R., and Morrow A.L. Chronic ethanol consumption differentially alters the expression of gamma-aminobutyric acidA receptor subunit mRNAs in rat cerebral cortex: competitive, quantitative reverse transcriptase-polymerase chain reaction analysis. Mol. Pharmacol. 48 (1995) 861-868
9. Di Chiara G., and Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc. Natl. Acad. Sci. U. S. A. 85 (1988) 5274-5278
10. Eggers E.D., and Berger A.J. Mechanisms for the modulation of native glycine receptor channels by ethanol. J. Neurophysiol. 91 (2004) 2685-2695
11. Engelmann M., Landgraf R., and Wotjak C.T. The hypothalamic-neurohypophysial system regulates the hypothalamic-pituitary-adrenal axis under stress: an old concept revisited. Front. Neuroendocrinol. 25 (2004) 132-149
12. Ericson M., Molander A., Stomberg R., and Soderpalm B. Taurine elevates dopamine levels in the rat nucleus accumbens; antagonism by strychnine. Eur. J. Neurosci. 23 (2006) 3225-3229
13. Eriksson K. Genetic selection for voluntary alcohol consumption in the albino rat. Science 159 (1968) 739-741
14. Fahlke C., Hansen S., Engel J.A., and Hard E. Effects of ventral striatal 6-OHDA lesions or amphetamine sensitization on ethanol consumption in the rat. Pharmacol. Biochem. Behav. 47 (1994) 345-349
15. Gonzales R.A., Job M.O., and Doyon W.M. The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacol. Ther. 103 (2004) 121-146
16. Grant K.A. Emerging neurochemical concepts in the actions of ethanol at ligand-gated ion channels. Behav. Pharmacol. 5 (1994) 383-404
17. Grudzinska J., Schemm R., Haeger S., Nicke A., Schmalzing G., Betz H., and Laube B. The beta subunit determines the ligand binding properties of synaptic glycine receptors. Neuron 45 (2005) 727-739
18. Handford C.A., Lynch J.W., Baker E., Webb G.C., Ford J.H., Sutherland G.R., and Schofield P.R. The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes. Brain Res. Mol. Brain Res. 35 (1996) 211-219
19. Harvey R.J., Schmieden V., Von Holst A., Laube B., Rohrer H., and Betz H. Glycine receptors containing the alpha4 subunit in the embryonic sympathetic nervous system, spinal cord and male genital ridge. Eur. J. Neurosci. 12 (2000) 994-1001
20. Heffner T.G., Hartman J.A., and Seiden L.S. A rapid method for the regional dissection of the rat brain. Pharmacol. Biochem. Behav. 13 (1980) 453-456
21. Heilig M., and Egli M. Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacol. Ther. 111 (2006) 855-876
22. Ivanova E., Muller U., and Wassle H. Characterization of the glycinergic input to bipolar cells of the mouse retina. Eur. J. Neurosci. 23 (2006) 350-364
23. Kirsch J. Glycinergic transmission. Cell Tissue Res. 326 (2006) 535-540
24. Koob G.F. A role for GABA mechanisms in the motivational effects of alcohol. Biochem. Pharmacol. 68 (2004) 1515-1525
25. Koob G.F., and Bloom F.E. Cellular and molecular mechanisms of drug dependence. Science 242 (1988) 715-723
26. Lape R., Colquhoun D., and Sivilotti L.G. On the nature of partial agonism in the nicotinic receptor superfamily. Nature 454 (2008) 722-727
27. Laube B., Maksay G., Schemm R., and Betz H. Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses?. Trends Pharmacol. Sci. 23 (2002) 519-527
28. Lynch J.W. Native glycine receptor subtypes and their physiological roles. Neuropharmacology 56 1 (2009) 303-309
29. Malosio M.L., Marqueze-Pouey B., Kuhse J., and Betz H. Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain. EMBO J. 10 (1991) 2401-2409
30. Mangin J.M., Baloul M., Prado De Carvalho L., Rogister B., Rigo J.M., and Legendre P. Kinetic properties of the alpha2 homo-oligomeric glycine receptor impairs a proper synaptic functioning. J. Physiol. 553 (2003) 369-386
31. Martin G., and Siggins G.R. Electrophysiological evidence for expression of glycine receptors in freshly isolated neurons from nucleus accumbens. J. Pharmacol. Exp. Ther. 302 (2002) 1135-1145
32. McBride W.J., Schultz J.A., Kimpel M.W., McClintick J.N., Wang M., You J., and Rodd Z.A. Differential effects of ethanol in the nucleus accumbens shell of alcohol-preferring (P), alcohol-non-preferring (NP) and Wistar rats: a proteomics study. Pharmacol. Biochem. Behav. 92 2 (2009) 304-313
33. Molander A., and Soderpalm B. Accumbal strychnine-sensitive glycine receptors: an access point for ethanol to the brain reward system. Alcohol Clin. Exp. Res. 29 (2005) 27-37
34. Molander A., and Soderpalm B. Glycine receptors regulate dopamine release in the rat nucleus accumbens. Alcohol Clin. Exp. Res. 29 (2005) 17-26
35. Molander A., Lof E., Stomberg R., Ericson M., and Soderpalm B. Involvement of accumbal glycine receptors in the regulation of voluntary ethanol intake in the rat. Alcohol Clin. Exp. Res. 29 (2005) 38-45
36. Molander A., Lido H.H., Lof E., Ericson M., and Soderpalm B. The glycine reuptake inhibitor Org 25935 decreases ethanol intake and preference in male Wistar rats. Alcohol Alcohol. 42 (2007) 11-18
37. O'Brien C.P. Review. Evidence-based treatments of addiction. Philos. Trans. R. Soc. Lond. B Biol. Sci. 363 (2008) 3277-3286
38. Perkins D.I., Trudell J.R., Crawford D.K., Alkana R.L., and Davies D.L. Targets for ethanol action and antagonism in loop 2 of the extracellular domain of glycine receptors. J. Neurochem. 106 (2008) 1337-1349
39. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29 (2001) e45
40. Quertement E., Dahchour A., Ward R.J., and De Witte P. Ethanol induces taurine release in the amygdala: an in vivo microdialysis study. Addict. Biol. 4 (1999) 47-54
41. Rampon C., Luppi P.H., Fort P., Peyron C., and Jouvet M. Distribution of glycine-immunoreactive cell bodies and fibers in the rat brain. Neuroscience 75 (1996) 737-755
42. Rassnick S., Stinus L., and Koob G.F. The effects of 6-hydroxydopamine lesions of the nucleus accumbens and the mesolimbic dopamine system on oral self-administration of ethanol in the rat. Brain Res. 623 (1993) 16-24
43. Vengeliene V., Bilbao A., Molander A., and Spanagel R. Neuropharmacology of alcohol addiction. Br. J. Pharmacol. 154 (2008) 299-315
44. Wise R.A., and Rompre P.P. Brain dopamine and reward. Annu. Rev. Psychol. 40 (1989) 191-225
45. Woodruff G.N., McCarthy P.S., and Walker R.J. Studies on the pharmacology of neurones in the nucleus accumbens of the rat. Brain Res. 115 (1976) 233-242
46. Yang Z., Cromer B.A., Harvey R.J., Parker M.W., and Lynch J.W. A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore. J. Neurochem. 103 (2007) 580-589
47. Yang Z., Aubrey K.R., Alroy I., Harvey R.J., Vandenberg R.J., and Lynch J.W. Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine. Biochem. Pharmacol. 76 (2008) 1014-1023
48. Yevenes G.E., Peoples R.W., Tapia J.C., Parodi J., Soto X., Olate J., and Aguayo L.G. Modulation of glycine-activated ion channel function by G-protein betagamma subunits. Nat. Neurosci. 6 (2003) 819-824
49. Yevenes G.E., Moraga-Cid G., Guzman L., Haeger S., Oliveira L., Olate J., Schmalzing G., and Aguayo L.G. Molecular determinants for G protein betagamma modulation of ionotropic glycine receptors. J. Biol. Chem. 281 (2006) 39300-39307
50. Yevenes G.E., Moraga-Cid G., Peoples R.W., Schmalzing G., and Aguayo L.G. A selective G betagamma-linked intracellular mechanism for modulation of a ligand-gated ion channel by ethanol. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 20523-20528
51. Swedish Health Technology Board (2001) Behandling av alkohol-och narkotikaproblem. En evidensbaserad kunskapssammanställning. Statens beredning för medicinsk utvärdering, rapport nr 156. SBU, Stockholm.