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Volumn 33, Issue 4, 2012, Pages 352-368

Expression, purification, and characterization of RGD-mda-7, A his-tagged mda-7/IL-24 mutant protein

Author keywords

antitumor; integrin V 3V 5; mda 7 il 24; mutant; RGD

Indexed keywords

ANTINEOPLASTIC AGENT; ARGINYLGLYCYLASPARTIC ACID MELANOMA DIFFERENTIATION ASSOCIATED GENE 7; GAMMA INTERFERON; IMMUNOSTIMULATING AGENT; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84866344739     PISSN: 15321819     EISSN: 15324230     Source Type: Journal    
DOI: 10.1080/15321819.2012.659782     Document Type: Article
Times cited : (10)

References (25)
  • 1
    • 0029558740 scopus 로고
    • Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression
    • Jiang, H.; Lin, J. J.; Su, Z. Z.; Goldstein, N. I.; Fisher, P. B. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene 1995, 11, 2477-2486. (Pubitemid 26023815)
    • (1995) Oncogene , vol.11 , Issue.12 , pp. 2477-2486
    • Jiang, H.1    Lin, J.J.2    Su, Z.-Z.3    Goldstein, N.I.4    Fisher, P.B.5
  • 2
    • 0037097637 scopus 로고    scopus 로고
    • The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24
    • Caudell, E. G.; Mumm, J. B.; Poindexter, N.; Ekmekcioglu, S.; Mhashilkar, A. M.; Yang, X. H.; Retter, M. W.; Hill, P.; Chada, S.; Grimm, E. A. The protein product of the tumor suppressor gene, melanoma differentiation- associated gene 7, exhibits immunostimulatory activity and is designated IL-24. J. Immunol. 2002, 168, 6041-6046. (Pubitemid 34620018)
    • (2002) Journal of Immunology , vol.168 , Issue.12 , pp. 6041-6046
    • Caudell, E.G.1    Mumm, J.B.2    Poindexter, N.3    Ekmekcioglu, S.4    Mhashilkar, A.M.5    Yang, X.H.6    Retter, M.W.7    Hill, P.8    Chada, S.9    Grimm, E.A.10
  • 6
    • 0037089491 scopus 로고    scopus 로고
    • Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR)
    • Pataer, A.; Vorburger, S. A.; Barber, G. N.; Chada, S.; Mhashilkar, A. M.; Zou-Yang, H.; Stewart, A. L.; Balachandran, S.; Roth, J. A.; Hunt, K. K.; Swisher, S. G. Adenoviral transfer of the melanoma differentiation-associated gene-7 (mda-7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR). Cancer Res. 2002, 62, 2239-2243. (Pubitemid 34411697)
    • (2002) Cancer Research , vol.62 , Issue.8 , pp. 2239-2243
    • Pataer, A.1    Vorburger, S.A.2    Barber, G.N.3    Chada, S.4    Mhashilkar, A.M.5    Zou-Yang, H.6    Stewart, A.L.7    Balachandran, S.8    Roth, J.A.9    Hunt, K.K.10    Swisher, S.G.11
  • 7
    • 17144375725 scopus 로고    scopus 로고
    • Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells
    • Gopalan, B.; Litvak, A.; Sharma, S.; Mhashilkar, A. M.; Chada, S.; Ramesh, R. Activation of the Fas-FasL signaling pathway by mda-7=IL-24 kills human ovarian cancer cells. Cancer Res. 2005, 65, 3017-3024. (Pubitemid 40524577)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3017-3024
    • Gopalan, B.1    Litvak, A.2    Sharma, S.3    Mhashilkar, A.M.4    Chada, S.5    Ramesh, R.6
  • 10
    • 28544435618 scopus 로고    scopus 로고
    • Is mda-7=IL-24 a ''magic bullet'' for cancer?
    • Fisher, P. B. Is mda-7=IL-24 a ''magic bullet'' for cancer? Cancer Res. 2005, 65, 10128-10138.
    • (2005) Cancer Res , vol.65 , pp. 10128-10138
    • Fisher, P.B.1
  • 12
    • 0037468264 scopus 로고    scopus 로고
    • Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner
    • DOI 10.1038/sj.onc.1206062
    • Su, Z. Z.; Lebedeva, I. V.; Sarkar, D.; Gopalkrishnan, R. V.; Sauane, M.; Sigmon, C.; Yacoub, A.; Valerie, K.; Dent, P.; Fisher, P. B. Melanoma differentiation associated gene-7, mda-7=IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner. Oncogene 2003, 22, 1164-1180. (Pubitemid 36363380)
    • (2003) Oncogene , vol.22 , Issue.8 , pp. 1164-1180
    • Su, Z.-Z.1    Lebedeva, I.V.2    Sarkar, D.3    Gopalkrishnan, R.V.4    Sauane, M.5    Sigmon, C.6    Yacoub, A.7    Valerie, K.8    Dent, P.9    Fisher, P.B.10
  • 13
    • 27844459421 scopus 로고    scopus 로고
    • Unique aspects of mda-7/IL-24 antitumor bystander activity: Establishing a role for secretion of MDA-7/IL-24 protein by normal cells
    • DOI 10.1038/sj.onc.1208911, PII 1208911
    • Su, Z.; Emdad, L.; Sauane, M.; Lebedeva, I. V.; Sarkar, D.; Gupta, P.; James, C. D.; Randolph, A.; Valerie, K.; Walter, M. R.; Dent, P.; Fisher, P. B. Unique aspects of mda-7=IL-24 antitumor bystander activity: Establishing a role for secretion of mda-7=IL-24 protein by normal cells. Oncogene 2005, 24, 7552-7566. (Pubitemid 41638030)
    • (2005) Oncogene , vol.24 , Issue.51 , pp. 7552-7566
    • Su, Z.1    Emdad, L.2    Sauane, M.3    Lebedeva, I.V.4    Sarkar, D.5    Gupta, P.6    James, C.D.7    Randolph, A.8    Valerie, K.9    Walter, M.R.10    Dent, P.11    Fisher, P.B.12
  • 14
    • 1542269303 scopus 로고    scopus 로고
    • Integrins: Roles in cancer development and as treatment targets
    • DOI 10.1038/sj.bjc.6601576
    • Jin, H.; Varner, J. Integrins: Roles in cancer development and as treatment targets. Br. J. Cancer 2004, 90, 561-565. (Pubitemid 38297190)
    • (2004) British Journal of Cancer , vol.90 , Issue.3 , pp. 561-565
    • Jin, H.1    Varner, J.2
  • 15
    • 0037318003 scopus 로고    scopus 로고
    • Integrin αvβ3 as a therapeutic target for blocking tumor-induced angiogenesis
    • DOI 10.2174/1389450033346830
    • Kumar, C. C. Integrin alpha v beta 3 as a therapeutic target for blocking tumor-induced angiogenesis. Curr. Drug Targets 2003, 4, 123-131. (Pubitemid 36553584)
    • (2003) Current Drug Targets , vol.4 , Issue.2 , pp. 123-131
    • Kumar, C.C.1
  • 16
    • 0037105767 scopus 로고    scopus 로고
    • Arginine-glycine-aspartic acid (RGD)-peptide binds to both tumor and tumor-endothelial cells in vivo
    • Zitzmann, S.; Ehemann, V.; Schwab, M. Arginine-glycine-aspartic acid (RGD)-peptide binds to both tumor and tumor endothelial cells in vivo. Cancer Res. 2002, 62, 5139-5143. (Pubitemid 35024582)
    • (2002) Cancer Research , vol.62 , Issue.18 , pp. 5139-5143
    • Zitzmann, S.1    Ehemann, V.2    Schwab, M.3
  • 18
    • 33750420717 scopus 로고    scopus 로고
    • 3 targeted radiotracers for tumor imaging
    • DOI 10.1021/mp060049x
    • Liu, S. Radiolabeled multimeric cyclic RGD peptides as integrin alphavbeta3 targeted radiotracers for tumor imaging. Mol. Pharm. 2006, 3, 472-487. (Pubitemid 44639125)
    • (2006) Molecular Pharmaceutics , vol.3 , Issue.5 , pp. 472-487
    • Liu, S.1
  • 19
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
    • DOI 10.1126/science.279.5349.377
    • Arap, W.; Pasqualini, R.; Ruoslahti, E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 1998, 279, 377-380. (Pubitemid 28063372)
    • (1998) Science , vol.279 , Issue.5349 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 21
    • 1842787584 scopus 로고    scopus 로고
    • Inhibition of tumor growth by intramuscular injection of cDNA encoding tumor necrosis factor α coupled to NGR and RGD tumor-homing peptides
    • DOI 10.1089/104303404322959524
    • Zarovni, N.; Monaco, L.; Corti, A. Inhibition of tumor growth by intramuscular injection of cDNA encoding tumor necrosis factor alpha coupled to NGR and RGD tumor-homing peptides. Hum. Gene Ther. 2004, 15, 373-382. (Pubitemid 38469779)
    • (2004) Human Gene Therapy , vol.15 , Issue.4 , pp. 373-382
    • Zarovni, N.1    Monaco, L.2    Corti, A.3
  • 22
    • 54349120011 scopus 로고    scopus 로고
    • Ad-MDA-7; INGN 241: A review of preclinical and clinical experience
    • Eager, R.; Harle, L.; Nemunaitis, J. Ad-MDA-7; INGN 241: A review of preclinical and clinical experience. Expert Opin. Biol. Ther. 2008, 8, 1633-1643.
    • (2008) Expert Opin. Biol. Ther. , vol.8 , pp. 1633-1643
    • Eager, R.1    Harle, L.2    Nemunaitis, J.3
  • 23
    • 33846205598 scopus 로고    scopus 로고
    • N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity
    • DOI 10.1158/0008-5472.CAN-06-1887
    • Sauane, M.; Gupta, P.; Lebedeva, I. V.; Su, Z. Z.; Sarkar, D.; Randolph, A.; Valerie, K.; Gopalkrishnan, R. V.; Fisher, P. B. N-Glycosylation of MDA-7=IL-24 is dispensable for tumor cell-specific apoptosis and ''bystander'' antitumor activity. Cancer Res. 2006, 66, 11869-11877. (Pubitemid 46094199)
    • (2006) Cancer Research , vol.66 , Issue.24 , pp. 11869-11877
    • Sauane, M.1    Gupta, P.2    Lebedeva, I.V.3    Su, Z.-Z.4    Sarkar, D.5    Randolph, A.6    Valerie, K.7    Gopalkrishnan, R.V.8    Fisher, P.B.9
  • 25
    • 0037375977 scopus 로고    scopus 로고
    • Restoring apoptosis as a strategy for cancer gene therapy: Focus on p53 and mda-7
    • DOI 10.1016/S1044-579X(02)00134-7, PII S1044579X02001347
    • Lebedeva, I. V.; Su, Z. Z.; Sarkar, D.; Fisher, P. B. Restoring apoptosis as a strategy for cancer gene therapy: Focus on p53 and mda-7. Semin. Cancer Biol. 2003, 13, 169-178. (Pubitemid 36315934)
    • (2003) Seminars in Cancer Biology , vol.13 , Issue.2 , pp. 169-178
    • Lebedeva, I.V.1    Su, Z.-Z.2    Sarkar, D.3    Fisher, P.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.