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Volumn 36, Issue 3, 2012, Pages 248-255

Processed Panax ginseng, sun ginseng, decreases oxidative damage induced by tert-butyl hydroperoxide via regulation of antioxidant enzyme and anti-apoptotic molecules in hepG2 cells

Author keywords

Antioxidant activity; Hepg2; Panax ginseng; Sun ginseng; Tert butyl hydroperoxide

Indexed keywords

PANAX GINSENG;

EID: 84866337201     PISSN: 12268453     EISSN: None     Source Type: Journal    
DOI: 10.5142/jgr.2012.36.3.248     Document Type: Article
Times cited : (30)

References (30)
  • 2
    • 0037087202 scopus 로고    scopus 로고
    • Role of mitochondria in alcoholic liver injury
    • Adachi M, Ishii H. Role of mitochondria in alcoholic liver injury. Free Radic Biol Med 2002;32:487-491.
    • (2002) Free Radic Biol Med , vol.32 , pp. 487-491
    • Adachi, M.1    Ishii, H.2
  • 3
    • 79951783214 scopus 로고    scopus 로고
    • Effects of Fermented Red Ginseng Extracts on Hyperglycemia in Streptozotocin-induced Diabetic Rats
    • Kim HJ, Chae IG, Lee SG, Jeong HJ, Lee EJ, Lee IS. Effects of Fermented Red Ginseng Extracts on Hyperglycemia in Streptozotocin-induced Diabetic Rats. J Ginseng Res 2010;34:104-112.
    • (2010) J Ginseng Res , vol.34 , pp. 104-112
    • Kim, H.J.1    Chae, I.G.2    Lee, S.G.3    Jeong, H.J.4    Lee, E.J.5    Lee, I.S.6
  • 4
    • 79951800917 scopus 로고    scopus 로고
    • Ginseng for Reducing the Blood Pressure in Patients with Hypertension: A Systematic Review and Meta-Analysis
    • Hur MH, Lee MS, Yang HJ, Kim C, Bae IL, Ernst E. Ginseng for Reducing the Blood Pressure in Patients with Hypertension: A Systematic Review and Meta-Analysis. J Ginseng Res 2010;34:342-347.
    • (2010) J Ginseng Res , vol.34 , pp. 342-347
    • Hur, M.H.1    Lee, M.S.2    Yang, H.J.3    Kim, C.4    Bae, I.L.5    Ernst, E.6
  • 6
    • 84862931744 scopus 로고    scopus 로고
    • Processed Panax ginseng, sun ginseng increases type I collagen by regulating MMP-1 and TIMP-1 expression in human dermal fibroblasts
    • Song KC, Chang TS, Lee H, Kim J, Park JH, Hwang GS. Processed Panax ginseng, sun ginseng increases type I collagen by regulating MMP-1 and TIMP-1 expression in human dermal fibroblasts. J Ginseng Res 2012;36:61-67.
    • (2012) J Ginseng Res , vol.36 , pp. 61-67
    • Song, K.C.1    Chang, T.S.2    Lee, H.3    Kim, J.4    Park, J.H.5    Hwang, G.S.6
  • 7
    • 33748175972 scopus 로고    scopus 로고
    • American ginseng stimulates insulin production and prevents apoptosis through regulation of uncoupling protein-2 in cultured beta cells
    • Luo JZ, Luo L. American ginseng stimulates insulin production and prevents apoptosis through regulation of uncoupling protein-2 in cultured beta cells. Evid Based Complement Alternat Med 2006;3:365-372.
    • (2006) Evid Based Complement Alternat Med , vol.3 , pp. 365-372
    • Luo, J.Z.1    Luo, L.2
  • 9
    • 0030767339 scopus 로고    scopus 로고
    • Protection of rat liver microsomes against carbon tetrachloride-induced lipid peroxidation by red ginseng saponin through cytochrome P450 inhibition
    • Kim HJ, Chun YJ, Park JD, Kim SI, Roh JK, Jeong TC. Protection of rat liver microsomes against carbon tetrachloride-induced lipid peroxidation by red ginseng saponin through cytochrome P450 inhibition. Planta Med 1997;63:415-418.
    • (1997) Planta Med , vol.63 , pp. 415-418
    • Kim, H.J.1    Chun, Y.J.2    Park, J.D.3    Kim, S.I.4    Roh, J.K.5    Jeong, T.C.6
  • 11
    • 33749451019 scopus 로고    scopus 로고
    • Reduction of cisplatin-induced nephrotoxicity by ginsenosides isolated from processed ginseng in cultured renal tubular cells
    • Baek SH, Piao XL, Lee UJ, Kim HY, Park JH. Reduction of cisplatin-induced nephrotoxicity by ginsenosides isolated from processed ginseng in cultured renal tubular cells. Biol Pharm Bull 2006;29:2051-2055.
    • (2006) Biol Pharm Bull , vol.29 , pp. 2051-2055
    • Baek, S.H.1    Piao, X.L.2    Lee, U.J.3    Kim, H.Y.4    Park, J.H.5
  • 12
    • 74249120888 scopus 로고    scopus 로고
    • Platelet antiaggregating activity of ginsenosides isolated from processed ginseng
    • Lee JG, Lee YY, Kim SY, Pyo JS, Yun-Choi HS, Park JH. Platelet antiaggregating activity of ginsenosides isolated from processed ginseng. Pharmazie 2009;64:602-604.
    • (2009) Pharmazie , vol.64 , pp. 602-604
    • Lee, J.G.1    Lee, Y.Y.2    Kim, S.Y.3    Pyo, J.S.4    Yun-Choi, H.S.5    Park, J.H.6
  • 13
    • 77953397753 scopus 로고    scopus 로고
    • Effects of heat-processed ginseng and its active component ginsenoside 20(S)-Rg3 on the progression of renal damage and dysfunction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty rats
    • Kang KS, Yamabe N, Kim HY, Park JH, Yokozawa T. Effects of heat-processed ginseng and its active component ginsenoside 20(S)-Rg3 on the progression of renal damage and dysfunction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty rats. Biol Pharm Bull 2010;33:1077-1081.
    • (2010) Biol Pharm Bull , vol.33 , pp. 1077-1081
    • Kang, K.S.1    Yamabe, N.2    Kim, H.Y.3    Park, J.H.4    Yokozawa, T.5
  • 14
    • 77956098145 scopus 로고    scopus 로고
    • Prevention of tertiary butyl hydroperoxide induced oxidative impairment and cell death by a novel antioxidant protein molecule isolated from the herb, Phyllanthus niruri
    • Sarkar MK, Sil PC. Prevention of tertiary butyl hydroperoxide induced oxidative impairment and cell death by a novel antioxidant protein molecule isolated from the herb, Phyllanthus niruri. Toxicol In Vitro 2010;24:1711-1719.
    • (2010) Toxicol In Vitro , vol.24 , pp. 1711-1719
    • Sarkar, M.K.1    Sil, P.C.2
  • 15
    • 33749519154 scopus 로고    scopus 로고
    • Phenolic compounds protect HepG2 cells from oxidative damage: Relevance of glutathione levels
    • Lima CF, Fernandes-Ferreira M, Pereira-Wilson C. Phenolic compounds protect HepG2 cells from oxidative damage: relevance of glutathione levels. Life Sci 2006;79:2056-2068.
    • (2006) Life Sci , vol.79 , pp. 2056-2068
    • Lima, C.F.1    Fernandes-Ferreira, M.2    Pereira-Wilson, C.3
  • 17
    • 34748876914 scopus 로고    scopus 로고
    • Effect of sun ginseng methanol extract on lipopolysaccharide-induced liver injury in rats
    • Kang KS, Yamabe N, Kim HY, Yokozawa T. Effect of sun ginseng methanol extract on lipopolysaccharide-induced liver injury in rats. Phytomedicine 2007;14:840-845.
    • (2007) Phytomedicine , vol.14 , pp. 840-845
    • Kang, K.S.1    Yamabe, N.2    Kim, H.Y.3    Yokozawa, T.4
  • 18
    • 26444610004 scopus 로고    scopus 로고
    • Hepatoprotective effect of 20(S)-ginsenosides Rg3 and its metabolite 20(S) ginsenoside Rh2 on tert-butyl hydroperoxide-induced liver injury
    • Lee HU, Bae EA, Han MJ, Kim DH. Hepatoprotective effect of 20(S)-ginsenosides Rg3 and its metabolite 20(S) ginsenoside Rh2 on tert-butyl hydroperoxide-induced liver injury. Biol Pharm Bull 2005;28:1992-1994.
    • (2005) Biol Pharm Bull , vol.28 , pp. 1992-1994
    • Lee, H.U.1    Bae, E.A.2    Han, M.J.3    Kim, D.H.4
  • 19
    • 0030898379 scopus 로고    scopus 로고
    • Protective effects of red ginseng saponins against carbon tetrachloride-induced hepatotoxicity in Sprague Dawley rats
    • Jeong TC, Kim HJ, Park JI, Ha CS, Park JD, Kim SI, Roh JK. Protective effects of red ginseng saponins against carbon tetrachloride-induced hepatotoxicity in Sprague Dawley rats. Planta Med 1997;63:136-140.
    • (1997) Planta Med , vol.63 , pp. 136-140
    • Jeong, T.C.1    Kim, H.J.2    Park, J.I.3    Ha, C.S.4    Park, J.D.5    Kim, S.I.6    Roh, J.K.7
  • 20
    • 0029620247 scopus 로고
    • Hepatoprotective activity of xanthones and xanthonolignoids against tert-butylhydroperoxide-induced toxicity in isolated rat hepatocytes: Comparison with silybin
    • Fernandes ER, Carvalho FD, Remiao FG, Bastos ML, Pinto MM, Gottlieb OR. Hepatoprotective activity of xanthones and xanthonolignoids against tert-butylhydroperoxide-induced toxicity in isolated rat hepatocytes: comparison with silybin. Pharm Res 1995;12:1756-1760.
    • (1995) Pharm Res , vol.12 , pp. 1756-1760
    • Fernandes, E.R.1    Carvalho, F.D.2    Remiao, F.G.3    Bastos, M.L.4    Pinto, M.M.5    Gottlieb, O.R.6
  • 21
    • 73449087616 scopus 로고    scopus 로고
    • Liv.52 protects HepG2 cells from oxidative damage induced by tertbutyl hydroperoxide
    • Vidyashankar S, Mitra SK, Nandakumar KS. Liv.52 protects HepG2 cells from oxidative damage induced by tertbutyl hydroperoxide. Mol Cell Biochem 2010;333:41-48.
    • (2010) Mol Cell Biochem , vol.333 , pp. 41-48
    • Vidyashankar, S.1    Mitra, S.K.2    Nandakumar, K.S.3
  • 23
    • 0035885202 scopus 로고    scopus 로고
    • Tert-butyl hydroperoxide-induced lipid signaling in hepatocytes: Involvement of glutathione and free radicals
    • Martin C, Martinez R, Navarro R, Ruiz-Sanz JI, Lacort M, Ruiz-Larrea MB. tert-butyl hydroperoxide-induced lipid signaling in hepatocytes: involvement of glutathione and free radicals. Biochem Pharmacol 2001;62:705-712.
    • (2001) Biochem Pharmacol , vol.62 , pp. 705-712
    • Martin, C.1    Martinez, R.2    Navarro, R.3    Ruiz-Sanz, J.I.4    Lacort, M.5    Ruiz-Larrea, M.B.6
  • 25
    • 79955415704 scopus 로고    scopus 로고
    • Desalinated underground seawater of Jeju Island (Korea) improves lipid metabolism in mice fed diets containing high fat and increases antioxidant potential in t-BHP treated HepG2 cells
    • Noh JR, Gang GT, Kim YH, Yang KJ, Lee CH, Na OS, Kim GJ, Oh WK, Lee YD. Desalinated underground seawater of Jeju Island (Korea) improves lipid metabolism in mice fed diets containing high fat and increases antioxidant potential in t-BHP treated HepG2 cells. Nutr Res Pract 2010;4:3-10.
    • (2010) Nutr Res Pract , vol.4 , pp. 3-10
    • Noh, J.R.1    Gang, G.T.2    Kim, Y.H.3    Yang, K.J.4    Lee, C.H.5    Na, O.S.6    Kim, G.J.7    Oh, W.K.8    Lee, Y.D.9
  • 26
    • 0027209389 scopus 로고
    • Strategies of antioxidant defense
    • Sies H. Strategies of antioxidant defense. Eur J Biochem 1993;215:213-219.
    • (1993) Eur J Biochem , vol.215 , pp. 213-219
    • Sies, H.1
  • 27
    • 69249159159 scopus 로고    scopus 로고
    • Antioxidant and apoptotic effects of Korean white ginseng extracted with the same ratio of protopanaxadiol and protopanaxatriol saponins in human hepatoma HepG2 cells
    • Lee M, Sorn S, Baek S, Jang S, Kim S. Antioxidant and apoptotic effects of Korean white ginseng extracted with the same ratio of protopanaxadiol and protopanaxatriol saponins in human hepatoma HepG2 cells. Ann N Y Acad Sci 2009;1171:217-227.
    • (2009) Ann N Y Acad Sci , vol.1171 , pp. 217-227
    • Lee, M.1    Sorn, S.2    Baek, S.3    Jang, S.4    Kim, S.5
  • 28
    • 0033789365 scopus 로고    scopus 로고
    • In vivo metabolism of tert-butyl hydroperoxide to methyl radicals. EPR spin-trapping and DNA methylation studies
    • Hix S, Kadiiska MB, Mason RP, Augusto O. In vivo metabolism of tert-butyl hydroperoxide to methyl radicals. EPR spin-trapping and DNA methylation studies. Chem Res Toxicol 2000;13:1056-1064.
    • (2000) Chem Res Toxicol , vol.13 , pp. 1056-1064
    • Hix, S.1    Kadiiska, M.B.2    Mason, R.P.3    Augusto, O.4
  • 29
    • 0032899637 scopus 로고    scopus 로고
    • Contribution of increased mitochondrial free Ca2+ to the mitochondrial permeability transition induced by tert-butylhydroperoxide in rat hepatocytes
    • Byrne AM, Lemasters JJ, Nieminen AL. Contribution of increased mitochondrial free Ca2+ to the mitochondrial permeability transition induced by tert-butylhydroperoxide in rat hepatocytes. Hepatology 1999;29:1523-1531.
    • (1999) Hepatology , vol.29 , pp. 1523-1531
    • Byrne, A.M.1    Lemasters, J.J.2    Nieminen, A.L.3
  • 30
    • 78751496958 scopus 로고    scopus 로고
    • Anti-apoptotic effects of red ginseng on oxidative stress induced by hydrogen peroxide in SK-N-SH cells
    • Kim EH, Lee MJ, Kim IH, Pyo S, Choi KT, Rhee DK. Anti-apoptotic effects of red ginseng on oxidative stress induced by hydrogen peroxide in SK-N-SH cells. J Ginseng Res 2010;34:138-144.
    • (2010) J Ginseng Res , vol.34 , pp. 138-144
    • Kim, E.H.1    Lee, M.J.2    Kim, I.H.3    Pyo, S.4    Choi, K.T.5    Rhee, D.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.