New HPLC method to detect individual opioids (heroin and tramadol) and their metabolites in the blood of rats on combination treatment

Journal of Chromatographic Science

Volumn 50, Issue 8, 2012, Pages 658-665

  Mahdy, Tarek ^a   El Shihi, Taha H ^b   Emara, Mostafa M ^c   Giorgi, Mario ^d  

^a Forensic Medicine Authority   (Egypt)

^b National Centre for Social and Criminological Research   (Egypt)

^c Al Azhar University   (Egypt)

^d UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DERIVATIVE; MORPHINE DERIVATIVE; NARCOTIC ANALGESIC AGENT; TRAMADOL;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; BLOOD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; PH; RAT; REGRESSION ANALYSIS; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; WISTAR RAT;

ANALGESICS, OPIOID; ANALYSIS OF VARIANCE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROGEN-ION CONCENTRATION; LEAST-SQUARES ANALYSIS; MORPHINE DERIVATIVES; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TRAMADOL;

RATTUS;

EID: 84866332025     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chromsci/bms066     Document Type: Article

References (37)

1. Shesser, R., Jotte, R., Olshaker, J.; The contribution of impurities to the acute morbidity of illegal drug use; American Journal of Emergency Medicine, (1991); 9: 336-342.
2. Yeh, S.Y., McQuinn, R.L., Gorodetzky, C.W.; Urinary excretion of heroin and its metabolites in man; Journal of Pharmacology and Experimental Therapeutics, (1976); 196: 249-256.
3. Salmon, A.Y., Goren, Z., Avissar, Y., Soreq, H.; Human erythrocyte but not brain acetylchloninesterase hydrolyses heroin to morphine; Clinical and Experimental Pharmacology and Physiology, (1999); 26: 596-600. (Pubitemid 29369917)
4. Way, E.L., Kemp, J.W., Young, J.M., Grassetti, D.R.; The pharmacologic effects of heroin in relationship to its rate of biotransformation; Journal of Pharmacology and Experimental Therapeutics, (1960); 129: 144-154.
5. Umans, J.G., Inturrisi, C.E.; Pharmacodynamics of subcutaneously administered diacetylmorphine, 6-acetylmorphine and morphine in mice; Journal of Pharmacology and Experimental Therapeutics, (1981); 218: 409-415. (Pubitemid 11044116)
6. Vickers, M.D., O'Flaherty, D., Szekely, S.M., Read, M., Yoshizumi, J.; Tramadol: Pain relief by an opioid without depression of respiration; Anaesthesia, (1992); 47: 291-296.
7. Hennies, H.H., Friderichs, E., Schneider, J.; Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids; Arzneimittelforschung, (1988); 38: 877-880.
8. Poulsen, L., Arendt-Nielsen, L., Brosen, K., Sindrup, S.H.; The hypoalgesic effect of tramadol in relation to CYP2D6; Clinical Pharmacology and Therapeutics, (1996); 60: 636-644. (Pubitemid 27025910)
9. Yalein, I., Aksu, F., Belzung, C.; Effects of desipramine and tramadol in a chronic mild stress model in mice are altered by yohimbine but not by pindolol; European Journal of Pharmacology, (2005); 514: 165-174. (Pubitemid 40720357)
10. Lintz, W., Barth, H., Becker, R., Frankus, E., Schmidt-Bothelt, E.; Pharmacokinetics of tramadol and bioavailability of enteral tramadol formulations. 2nd communication: Drops with ethanol; Arneimittelforschung, (1998); 48: 436-445. (Pubitemid 28247628)
11. Paar, W.D., Poche, S., Gerloff, J., Dengler, H.J. Polymorphic CYP2D6 mediates O-demethylation of the opioid analgesic tramadol; European Journal of Clinical Pharmacology, (1997); 53: 235-239. (Pubitemid 28018297)
12. Achilli, G., Cellerino, G.P., Melzi d'Eril, G.V., Tagliaro, F.; Determination of illicit drugs and related substances by high performance liquid chromatography with an electrochemical coulometric-array detector; Journal of Chromatography A, (1996); 729: 273-277. (Pubitemid 26135024)
13. Macchia, M., Bertini, S., Mori, C., Orlando, C., Papi, C., Placanica, G.; Efficient application of monolithic silica column to determination of illicit heroin street sample by HPLC; Farmaco, (2004); 59: 237-239. (Pubitemid 38251621)
14. Barrett, D.A., Shaw, P.N., Davis, S.S.; Determination of morphine and 6-acetylmorphine in plasma by high-performance liquid chromatography with fluorescence detection; Journal of Chromatography B, (1991); 566: 135-145.
15. Rop, P.P., Grimaldi, F., Burlea, J., Saint Legera, M.N.D., Viala, A.; Determination of 6-monoacetylmorphine and morphine in plasma, whole blood and urine using high-performance liquid chromatography with electrochemical detection; Journal of Chromatography B, (1994); 661: 245-253. (Pubitemid 24369543)
16. Dienes-Nagy, A., Rivier, L., Giroud, C., Augsburger, M., Mangin, P.; Method for quantification of morphine and its 3- and 6- glucuronides, codeine, codeine glucuronide and 6- monoacetylmorphine in human blood by liquid chromatography-electrospray mass spectrometry for routine analysis in forensic toxicology; Journal of Chromatography A, (1999); 854: 109-118. (Pubitemid 29387309)
17. Gergov, M., Nokua, P., Vuori, E., Ojanpera, I.; Simultaneous screening and quantification of 25 opioid drugs in post-mortem blood and urine by liquid chromatography-tandem mass spectrometry; Forensic Science International, (2009); 186: 36-43.
18. Elsing, B., Blaschke, G.; Achiral and chiral high-performance liquid chromatographic determination of tramadol and its major metabolites in urine after oral administration of racemic tramadol; Journal of Chromatography, (1993); 612: 223-230. (Pubitemid 23067180)
19. Ardakani, Y.H., Rouini, M.R.; Improved liquid chromatographic method for the simultaneous determination of tramadol and its three main metabolites in human plasma, urine and saliva; Journal of Pharmaceutical and Biomedical Analysis, (2007); 44: 1168-1173. (Pubitemid 47239287)
20. Nobilis, M., Kopecky, J., Kventina, J., Chladek, J., Svoboda, Z., Vorisek, V., et al.; High-performance liquid chromatographic determination of tramadol and its O-desmethylated metabolite in blood plasma. Application to a bioequivalence study in humans; Journal of Chromatography A, (2002); 949: 11-22. (Pubitemid 34183409)
21. Rouini, M.R., Ardakani, Y.H., Soltani, F., Aboul-Enein, H.Y., Foroumadi, A.; Development and validation of a rapid HPLC method for simultaneous determination of tramadol, and its two main metabolites in human plasma; Journal of Chromatography B, (2006); 830: 207-211. (Pubitemid 43075452)
22. Nobilis, M., Pastera, J., Anzenbacher, P., Svoboda, D., Kopecky, J., Perlik, F.; High-performance liquid chromatographic determination of tramadol in human plasma; Journal of Chromatography B, (1996); 681: 177-183. (Pubitemid 26193984)
23. Tao, Q., Stone, D.J., Jr., Borenstein, M.R., Jean-Bart, V., Codd, E.E., Coogan, T.P., et al.; Gas chromatographic method using nitrogenphosphorus detection for the measurement of tramadol and its O-desmethyl metabolite in plasma and brain tissue of mice and rats; Journal of Chromatography B, (2001); 763: 165-171. (Pubitemid 32972315)
24. Yeh, G.C., Sheu, M.T., Yen, C.L., Wang, Y.W., Liu, C.H., Ho, H.O.; High-performance liquid chromatographic method for determination of tramadol in human plasma; Journal of Chromatography B, (1999); 723: 247-253.
25. Gan, S.H., Ismail, R., Wan Adnan, W.A., Wan, Z.; Method development, validation of a high-performance liquid chromatographic method for tramadol in human plasma using liquid-liquid extraction; Journal of Chromatography B, (2002); 772: 123-129. (Pubitemid 34450759)
26. Giorgi, M., Soldani, G., Manera, C., Ferrarini, P., Sgorbini, M., Saccomanni, G.; Pharmacokinetics of tramadol and its metabolites M1, M2 and M5 in horses following intravenous, immediate release (fasted/fed) and sustained release single dose administration; Journal of Equine Veterinary Science, (2007); 27: 481-488. (Pubitemid 350122928)
27. Saccomanni, G., Del Carlo, S., Giorgi, M., Manera, C., Saba, A., Macchia, M.; Determination of tramadol and metabolites by HPLC-FL and HPLC-MS/MS in urine of dogs; Journal of Pharmaceutical and Biomedical Analysis, (2010); 53: 194-199.
28. Valle, M., Pavó n, J.M., Calvo, R., Campanero, M.A., Trocó niz, I.F.; Simultaneous determination of tramadol and its major active metabolite O-demethyltramadol by high-performance liquid chromatography with electrochemical detection; Journal of Chromatography B, (1999); 724: 83-89. (Pubitemid 29146023)
29. Guideline on bioanalytical method validation. EMEA/CHMP/EWP/ 192217/2009, (2009).
30. Fernandez, P., Morales, L., Vazquez, C., Bermejo, A.M., Tabernero, M.J.; HPLC-DAD determination of opioids, cocaine and their metabolites in plasma; Forensic Science International, (2006); 161: 31-35. (Pubitemid 44107679)
31. Ary, K., Rona, K.; LC determination of morphine and morphine glucuronides in human plasma by coulometric and UV detection; Journal of Pharmaceutical and Biomedical Analysis, (2001); 26: 179-187. (Pubitemid 32709933)
32. Bourquin, D., Lehmanna, T., Hämmig, R., Bührer, M., Brenneisen, R.; High-performance liquid chromatographic monitoring of intravenously administered diacetylmorphine and morphine and their metabolites in human plasma; Journal of Chromatography B, (1997); 694: 233-238. (Pubitemid 27274011)
33. Low, A.S., Taylor, R.B.; Analysis of common opiates and heroin metabolites in urine by high-performance liquid chromatography; Journal of Chromatography B, (1995); 663: 225-233.
34. Zuccaro, P., Ricciarello, R., Pichini, S., Pacifici, R., Altieri, I., Pellegrini, M., et al.; Simultaneous determination of heroin 6- monoacetylmorphine, morphine, and its glucuronides by liquid chromatography-atmospheric pressure ionspray-mass spectrometry; Journal of Analytical Toxicology, (1997); 21: 268-277. (Pubitemid 27349045)
35. United Nations. International Drug Control Programme, ST/NAR/ 27, (1995).
36. Moeller, M.R., Steinmeyer, S., Kraemer, T. Determination of drugs of abuse in blood; Journal of Chromatography B, (1998); 713: 91-109. (Pubitemid 28346481)
37. Godoy, A.L., De Moraes, N.V., Martinez, E.Z., Carvalho, T.M., Marques, M.P., Lanchote, V.L.; Simultaneous analysis of tramadol, O-desmethyltramadol, and N-desmethyltramadol enantiomers in rat plasma by high-performance liquid chromatography-tandem mass spectrometry: Application to pharmacokinetics; Chirality, (2011); 23: 287-293.