Non-Covalent Interaction between Polyubiquitin and GTP Cyclohydrolase 1 Dictates Its Degradation

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Zhao, Yu ^a   Zhu, Huaiping ^a   Zou, Ming Hui ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; ISOLEUCINE; LYSINE; POLYUBIQUITIN; PROTEASOME;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME STABILITY; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO CULTURE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SITE DIRECTED MUTAGENESIS; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; ENDOTHELIAL CELLS; GTP CYCLOHYDROLASE; HEK293 CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; ISOLEUCINE; LUNG; LYSINE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MYOCARDIUM; POLYUBIQUITIN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; UBIQUITINATION;

ANIMALIA;

EID: 84866317032     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043306     Document Type: Article

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