Norcantharidin Facilitates LPS-Mediated Immune Responses by Up-Regulation of AKT/NF-κB Signaling in Macrophages

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Zhao, Qufei ^a   Qian, Yu ^a   Li, Ruimei ^a   Tan, Binghe ^a   Han, Honghui ^a   Liu, Mingyao ^a   Qian, Min ^a   Du, Bing ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; NITRIC OXIDE; NORCANTHARIDIN; PROTEIN KINASE B; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL PERITONITIS; BINDING AFFINITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENZYME DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FEMALE; GEL MOBILITY SHIFT ASSAY; HOST RESISTANCE; IMMUNE RESPONSE; IMMUNOFLUORESCENCE TEST; IMMUNOMODULATION; MOUSE; NONHUMAN; PHAGOCYTOSIS; POLYMERASE CHAIN REACTION; PROTEIN BLOOD LEVEL; PROTEIN DNA BINDING; PROTEIN TRANSPORT; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ZYMOGRAPHY;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; NF-KAPPA B; PERITONITIS; PHAGOCYTOSIS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

BACTERIA (MICROORGANISMS);

EID: 84866285554     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044956     Document Type: Article

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