Insights into the phosphoregulation of β-secretase sorting signal by the VHS domain of GGA1

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Volumn 5, Issue 6, 2004, Pages 437-448

  Shiba, Tomoo ^a   Kametaka, Satoshi ^b   Kawasaki, Masato ^a   Shibata, Masahiro ^b   Waguri, Satoshi ^b   Uchiyama, Yasuo ^b   Wakatsuki, Soichi ^a  

^a INSTITUTE OF MATERIALS STRUCTURE SCIENCE   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

amyloid; secretase; Acidic cluster dileucine signal; Alzheimer's disease; BACE; GGA; Mannose 6 phosphate receptor; Phosphoregulation; Vesicle transport; VHS; X ray structure

Indexed keywords

ADAPTOR PROTEIN; AMYLOID BETA PROTEIN; ASPARTIC PROTEINASE; BETA SECRETASE; GLUTAMINE; GOLGI LOCALIZING GAMMA ADAPTIN EAR HOMOLOGY ARF INTERACTING PROTEIN; LYSINE; MEMBRANE PROTEIN; SERINE; SOLVENT; SOMATOMEDIN B RECEPTOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; ELECTRICITY; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; HYDROGEN BOND; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANS GOLGI NETWORK; X RAY CRYSTALLOGRAPHY;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ADP-RIBOSYLATION FACTORS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; ENDOPEPTIDASES; HELA CELLS; HUMANS; HYDROGEN BONDING; LEUCINE; LYSINE; MICROSCOPY, CONFOCAL; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SERINE; SURFACE PLASMON RESONANCE;

EID: 2942682767     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2004.00188.x     Document Type: Article

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