Prevention by parenteral aspirin of indomethacin-induced gastric lesions in rats: Mediation by salicylic acid

Digestive Diseases and Sciences

Volumn 47, Issue 7, 2002, Pages 1538-1545

  Komoike, Yusaku ^a   Takeeda, Masanori ^a   Tanaka, Akiko ^a   Kato, Shinichi ^a   Takeuchi, Koji ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Aspirin; Gastric lesion; Gastric motility; Nonsteroidal antiinflammatory drug; Prostaglandin; Rat; Salicylic acid

Indexed keywords

3,7 DIMETHYL 1 PROPARGYLXANTHINE; ACETYLSALICYLIC ACID; ADENOSINE; ADENOSINE DEAMINASE INHIBITOR; ADENOSINE RECEPTOR BLOCKING AGENT; ATROPINE; DICLOFENAC; FLURBIPROFEN; INDOMETACIN; MECLOFENAC; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; SALICYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG MECHANISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH HEMORRHAGE; STOMACH LESION; STOMACH MOTILITY; STOMACH PROTECTION;

ADENOSINE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; GASTRIC MUCOSA; GASTROINTESTINAL MOTILITY; INDOMETHACIN; INJECTIONS, SUBCUTANEOUS; MALE; RATS; RATS, SPRAGUE-DAWLEY; SALICYLIC ACID;

EID: 0036311008     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1015867119014     Document Type: Article

References (24)

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5. Role of gastric mucosal folds in formation of focal ulcers in the rat
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14. Nonsteroidal antiinflammatory agents inhibit stimulated neutrophil adhesion to endothelium: Adenosine dependent and independent mechanisms
15. Salicylates and sulfasalazine, but not glucocorticoids leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NF kappa B
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24. Gastric motility is a major factor in cold-restraint-induced lesion formation in rats