Synthesis and anticonvulsant properties of new mannich bases derived from 3,3-disubstituted pyrrolidine-2,5-diones. Part IV

Archiv der Pharmazie

Volumn 345, Issue 9, 2012, Pages 713-722

  Obniska, Jolanta ^a   Chlebek, Iwona ^a   Kamiński, Krzysztof ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Anticonvulsant activity; In vivo studies; N Mannich bases; Pyrrolidine 2,5 diones; Succinimides

Indexed keywords

3 METHYL 3 PHENYLPYRROLIDINE 2,5 DIONE; ANTICONVULSIVE AGENT; ETHOSUXIMIDE; N (MORPHOLIN 1 YL) METHYL 3 ETHYL 3 METHYLPYRROLIDINE 2,5 DIONE; N (MORPHOLIN 1 YL) METHYL 3 METHYL 3 PHENYLPYRROLIDINE 2,5 DIONE; N (MORPHOLIN 1 YL) METHYL 3,3 DIPHENYLPYRROLIDINE 2,5 DIONE; N [(4 BENZYLPIPERAZIN 1 YL) METHYL] 3 ETHYL 3 METHYLPYRROLIDINE 2,5 DIONE HYDROCHLORIDE; N [(4 BENZYLPIPERAZIN 1 YL) METHYL] 3 METHYL 3 PHENYLPYRROLIDINE 2,5 DIONE HYDROCHLORIDE; N [(4 BENZYLPIPERAZIN 1 YL) METHYL] 3,3 DIPHENYLPYRROLIDINE 2,5 DIONE; N [(4 BENZYLPIPERIDIN 1 YL) METHYL] 3 ETHYL 3 METHYLPYRROLIDINE 2,5 DIONE; N [(4 BENZYLPIPERIDIN 1 YL) METHYL] 3 METHYL 3 PHENYLPYRROLIDINE 2,5 DIONE; N [(4 BENZYLPIPERIDIN 1 YL) METHYL] 3,3 DIPHENYLPYRROLIDINE 2,5 DIONE; N [(4 CYCLOHEXYLPIPERAZIN 1 YL) METHYL] 3 ETHYL 3 METHYLPYRROLIDINE 2,5 DIONE; N [(4 CYCLOHEXYLPIPERAZIN 1 YL) METHYL] 3 METHYL 3 PHENYLPYRROLIDINE 2,5 DIONE; N [(4 CYCLOHEXYLPIPERAZIN 1 YL) METHYL] 3,3 DIPHENYLPYRROLIDINE 2,5 DIONE; N [(4 METHYLPIPERAZIN 1 YL) METHYL] 3 ETHYL 3 METHYLPYRROLIDINE 2,5 DIONE DIHYDROCHLORIDE; N [(4 METHYLPIPERAZIN 1 YL) METHYL] 3 METHYL 3 PHENYLPYRROLIDINE 2,5 DIONE DIHYDROCHLORIDE; N [(4 METHYLPIPERAZIN 1 YL) METHYL] 3,3 DIPHENYLPYRROLIDINE 2,5 DIONE; N [(4 PYRIMID 2 YL PIPERAZIN 1 YL) METHYL] 3 ETHYL 3 METHYLPYRROLIDINE 2,5 DIONE; N [(4 PYRIMID 2 YL PIPERAZIN 1 YL) METHYL] 3 METHYL 3 PHENYLPYRROLIDINE 2,5 DIONE; N [(4 PYRIMID 2 YL PIPERAZIN 1 YL) METHYL] 3,3 DIPHENYLPYRROLIDINE 2,5 DIONE; N [[4 (2 HYDROXYETHYL) PIPERAZIN 1 YL] METHYL] 3 ETHYL 3 METHYLPYRROLIDINE 2,5 DIONE DIHYDOCHLORIDE; N [[4 (2 HYDROXYETHYL) PIPERAZIN 1 YL] METHYL] 3 METHYL 3 PHENYLPYRROLIDINE 2,5 DIONE HYDROCHLORIDE; N [[4 (2 HYDROXYETHYL) PIPERAZIN 1 YL] METHYL] 3,3 DIPHENYLPYRROLIDINE 2,5 DIONE; PENTETRAZOLE; PHENYTOIN; UNCLASSIFIED DRUG; VALPROIC ACID;

ANTICONVULSANT ACTIVITY; ARTICLE; DRUG SYNTHESIS; ELECTRIC SHOCK; EPILEPSY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; ANTICONVULSANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ELECTROSHOCK; INJECTIONS, INTRAPERITONEAL; MALE; MANNICH BASES; MICE; MOLECULAR STRUCTURE; MOTOR ACTIVITY; PENTYLENETETRAZOLE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; SUCCINIMIDES;

EID: 84866252607     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201200092     Document Type: Article

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