-
1
-
-
51549113784
-
Recent developments in the immunobiology of rheumatoid arthritis
-
doi:10.1186/ar2370
-
Andersson AK, Li C, Brennan FM (2008) Recent developments in the immunobiology of rheumatoid arthritis. Arthritis Res Ther 10(2):204. doi:10.1186/ar2370
-
(2008)
Arthritis Res Ther
, vol.10
, Issue.2
, pp. 204
-
-
Andersson, A.K.1
Li, C.2
Brennan, F.M.3
-
2
-
-
67549107120
-
Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: A systematic literature research
-
doi:10.1136/ard.2008.093690
-
Salliot C, van der Heijde D (2009) Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: a systematic literature research. Ann Rheum Dis 68(7):1100-1104. doi:10.1136/ard.2008.093690
-
(2009)
Ann Rheum Dis
, vol.68
, Issue.7
, pp. 1100-1104
-
-
Salliot, C.1
Van Der Heijde, D.2
-
3
-
-
67549096874
-
Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: Integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E initiative
-
doi:10.1136/ard.2008.094474
-
Visser K, Katchamart W, Loza E, Martinez-Lopez JA, Salliot C, Trudeau J et al (2009) Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative. Ann Rheum Dis 68(7):1086-1093. doi:10.1136/ard.2008.094474
-
(2009)
Ann Rheum Dis
, vol.68
, Issue.7
, pp. 1086-1093
-
-
Visser, K.1
Katchamart, W.2
Loza, E.3
Martinez-Lopez, J.A.4
Salliot, C.5
Trudeau, J.6
-
4
-
-
0035985787
-
Molecular action of methotrexate in inflammatory diseases
-
Chan ES, Cronstein BN (2002) Molecular action of methotrexate in inflammatory diseases. Arthritis Res 4(4):266-273
-
(2002)
Arthritis Res
, vol.4
, Issue.4
, pp. 266-273
-
-
Chan, E.S.1
Cronstein, B.N.2
-
5
-
-
22944470530
-
Low-dose methotrexate: A mainstay in the treatment of rheumatoid arthritis
-
doi:10.1124/pr.57.2.3
-
Cronstein BN (2005) Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis. Pharmacol Rev 57(2):163-172. doi:10.1124/pr.57.2.3
-
(2005)
Pharmacol Rev
, vol.57
, Issue.2
, pp. 163-172
-
-
Cronstein, B.N.1
-
6
-
-
0032722979
-
Effect of methotrexate on blood purine and pyrimidine levels in patients with rheumatoid arthritis
-
Smoleńska Z, Kaznowska Z, Zarówny D, Simmonds HA, Smoleński RT (1999) Effect of methotrexate on blood purine and pyrimidine levels in patients with rheumatoid arthritis. Rheumatology (Oxford) 38(10):997-1002
-
(1999)
Rheumatology (Oxford)
, vol.38
, Issue.10
, pp. 997-1002
-
-
Smoleńska, Z.1
Kaznowska, Z.2
Zarówny, D.3
Simmonds, H.A.4
Smoleński, R.T.5
-
7
-
-
0034724938
-
Effects of methotrexate on nucleotide pools in normal human T cells and the CEM T cell line
-
Budzik GP, Colletti LM, Faltynek CR (2000) Effects of methotrexate on nucleotide pools in normal human T cells and the CEM T cell line. Life Sci 66(23):2297-2307
-
(2000)
Life Sci
, vol.66
, Issue.23
, pp. 2297-2307
-
-
Budzik, G.P.1
Colletti, L.M.2
Faltynek, C.R.3
-
8
-
-
0034119415
-
Methotrexate as a preferential cyclooxygenase 2 inhibitor in whole blood of patients with rheumatoid arthritis
-
Mello SB, Barros DM, Silva AS, Laurindo IM, Novaes GS (2000) Methotrexate as a preferential cyclooxygenase 2 inhibitor in whole blood of patients with rheumatoid arthritis. Rheumatology (Oxford) 39(5):533-536
-
(2000)
Rheumatology (Oxford)
, vol.39
, Issue.5
, pp. 533-536
-
-
Mello, S.B.1
Barros, D.M.2
Silva, A.S.3
Laurindo, I.M.4
Novaes, G.S.5
-
9
-
-
0037207972
-
Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68
-
doi:10.1002/art.10712
-
Montesinos MC, Desai A, Delano D, Chen JF, Fink JS, Jacobson MA et al (2003) Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68. Arthritis Rheum 48(1):240-247. doi:10.1002/art.10712
-
(2003)
Arthritis Rheum
, vol.48
, Issue.1
, pp. 240-247
-
-
Montesinos, M.C.1
Desai, A.2
Delano, D.3
Chen, J.F.4
Fink, J.S.5
Jacobson, M.A.6
-
10
-
-
0037331142
-
The anti-inflammatory actions of methotrexate are critically dependent upon the production of reactive oxygen species
-
Phillips DC, Woollard KJ, Griffiths HR (2003) The anti-inflammatory actions of methotrexate are critically dependent upon the production of reactive oxygen species. Br J Pharmacol 138(3): 501-511
-
(2003)
Br J Pharmacol
, vol.138
, Issue.3
, pp. 501-511
-
-
Phillips, D.C.1
Woollard, K.J.2
Griffiths, H.R.3
-
11
-
-
11444251484
-
The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules
-
doi:10.1016/j.clim.2004.09.001
-
Johnston A, Gudjonsson JE, Sigmundsdottir H, Ludviksson BR, Valdimarsson H (2005) The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules. Clin Immunol 114(2):154-163. doi:10.1016/j.clim.2004.09.001
-
(2005)
Clin Immunol
, vol.114
, Issue.2
, pp. 154-163
-
-
Johnston, A.1
Gudjonsson, J.E.2
Sigmundsdottir, H.3
Ludviksson, B.R.4
Valdimarsson, H.5
-
12
-
-
0037836114
-
Methotrexate inhibits interleukin-6 production in patients with juvenile rheumatoid arthritis
-
doi:10.1007/s00296-002-0267-y
-
Aggarwal A, Misra R (2003) Methotrexate inhibits interleukin-6 production in patients with juvenile rheumatoid arthritis. Rheumatol Int 23(3):134-137. doi:10.1007/s00296-002-0267-y
-
(2003)
Rheumatol Int
, vol.23
, Issue.3
, pp. 134-137
-
-
Aggarwal, A.1
Misra, R.2
-
13
-
-
0141997274
-
Inhibition of cytokine production by methotrexate. Studies in healthy volunteers and patients with rheumatoid arthritis
-
doi:10.1093/rheumatology/keg323
-
Gerards AH, de Lathouder S, de Groot ER, Dijkmans BA, Aarden LA (2003) Inhibition of cytokine production by methotrexate. Studies in healthy volunteers and patients with rheumatoid arthritis. Rheumatology 42(10):1189-1196. doi:10.1093/rheumatology/keg323
-
(2003)
Rheumatology
, vol.42
, Issue.10
, pp. 1189-1196
-
-
Gerards, A.H.1
De Lathouder, S.2
De Groot, E.R.3
Dijkmans, B.A.4
Aarden, L.A.5
-
14
-
-
27644575496
-
Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor kappaB-dependent pathway in patients with rheumatoid arthritis
-
doi:10.1186/ar1470
-
Kim KW, Cho ML, Park MK, Yoon CH, Park SH, Lee SH et al (2005) Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor kappaB-dependent pathway in patients with rheumatoid arthritis. Arthritis Res Ther 7(1):R139-R148. doi:10.1186/ar1470
-
(2005)
Arthritis Res Ther
, vol.7
, Issue.1
-
-
Kim, K.W.1
Cho, M.L.2
Park, M.K.3
Yoon, C.H.4
Park, S.H.5
Lee, S.H.6
-
15
-
-
39149121448
-
Interleukin-17 gene expression in patients with rheumatoid arthritis
-
doi:10.1007/s10165-007-0015-y
-
Kohno M, Tsutsumi A, Matsui H, Sugihara M, Suzuki T, Mamura M et al (2008) Interleukin-17 gene expression in patients with rheumatoid arthritis. Mod Rheumatol 18(1):15-22. doi:10.1007/s10165-007-0015-y
-
(2008)
Mod Rheumatol
, vol.18
, Issue.1
, pp. 15-22
-
-
Kohno, M.1
Tsutsumi, A.2
Matsui, H.3
Sugihara, M.4
Suzuki, T.5
Mamura, M.6
-
16
-
-
67651175878
-
Breaking old paradigms: Th17 cells in autoimmune arthritis
-
doi:10.1016/j.clim.2009.03.522
-
Peck A, Mellins ED (2009) Breaking old paradigms: Th17 cells in autoimmune arthritis. Clin Immunol 132(3):295-304. doi: 10.1016/j.clim.2009.03. 522
-
(2009)
Clin Immunol
, vol.132
, Issue.3
, pp. 295-304
-
-
Peck, A.1
Mellins, E.D.2
-
17
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
doi:10.1038/ni1261
-
Park H, Li Z, Yang XO, Chang SH, Nurieva R, Wang YH et al (2005) A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 6(11): 1133-1141. doi:10.1038/ni1261
-
(2005)
Nat Immunol
, vol.6
, Issue.11
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
-
18
-
-
0033134608
-
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
-
doi:10.1172/JCI5703
-
Kotake S, Udagawa N, Takahashi N, Matsuzaki K, Itoh K, Ishiyama S et al (1999) IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 103(9):1345-1352. doi:10.1172/JCI5703
-
(1999)
J Clin Invest
, vol.103
, Issue.9
, pp. 1345-1352
-
-
Kotake, S.1
Udagawa, N.2
Takahashi, N.3
Matsuzaki, K.4
Itoh, K.5
Ishiyama, S.6
-
19
-
-
64849100544
-
Genome-wide comparison between IL-17A-and IL-17F-induced effects in human rheumatoid arthritis synoviocytes
-
doi:10.4049/jimmunol.0801967
-
Zrioual S, Ecochard R, Tournadre A, Lenief V, Cazalis MA, Miossec P (2009) Genome-wide comparison between IL-17A-and IL-17F-induced effects in human rheumatoid arthritis synoviocytes. J Immunol 182(5):3112-3120. doi:10.4049/jimmunol.0801967
-
(2009)
J Immunol
, vol.182
, Issue.5
, pp. 3112-3120
-
-
Zrioual, S.1
Ecochard, R.2
Tournadre, A.3
Lenief, V.4
Cazalis, M.A.5
Miossec, P.6
-
20
-
-
1042267236
-
Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion
-
doi:10.1002/art.20001
-
Lubberts E, Koenders MI, Oppers-Walgreen B, van den Bersselaar L, Coenen-de Roo CJ, Joosten LA et al (2004) Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion. Arthritis Rheum 50(2): 650-659. doi:10.1002/art.20001
-
(2004)
Arthritis Rheum
, vol.50
, Issue.2
, pp. 650-659
-
-
Lubberts, E.1
Koenders, M.I.2
Oppers-Walgreen, B.3
Van Den Bersselaar, L.4
Coenen-De Roo, C.J.5
Joosten, L.A.6
-
21
-
-
70349968220
-
IL-17 as a future therapeutic target for rheumatoid arthritis
-
doi:10.1038/nrrheum.2009.179
-
van den Berg WB, Miossec P (2009) IL-17 as a future therapeutic target for rheumatoid arthritis. Nat Rev Rheumatol 5(10):549-553. doi:10.1038/nrrheum. 2009.179
-
(2009)
Nat Rev Rheumatol
, vol.5
, Issue.10
, pp. 549-553
-
-
Van Den Berg, W.B.1
Miossec, P.2
-
22
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
-
Nakae S, Nambu A, Sudo K, Iwakura Y (2003) Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 171(11):6173-6177
-
(2003)
J Immunol
, vol.171
, Issue.11
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
23
-
-
57349083145
-
Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory th17 responses
-
doi:10.1002/art.24126
-
Fujimoto M, Serada S, Mihara M, Uchiyama Y, Yoshida H, Koike N et al (2008) Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses. Arthritis Rheum 58(12):3710-3719. doi:10.1002/art.24126
-
(2008)
Arthritis Rheum
, vol.58
, Issue.12
, pp. 3710-3719
-
-
Fujimoto, M.1
Serada, S.2
Mihara, M.3
Uchiyama, Y.4
Yoshida, H.5
Koike, N.6
-
24
-
-
70449412259
-
Effects of methotrexate on plasma cytokines and cardiac remodeling and function in postmyocarditis rats
-
389720 doi:10.1155/2009/389720
-
Zhang Z, Zhao P, Li A, Lv X, Gao Y, Sun H et al (2009) Effects of methotrexate on plasma cytokines and cardiac remodeling and function in postmyocarditis rats. Mediators Inflamm 389720(1-9). doi:10.1155/2009/389720
-
(2009)
Mediators Inflamm
, Issue.1-9
-
-
Zhang, Z.1
Zhao, P.2
Li, A.3
Lv, X.4
Gao, Y.5
Sun, H.6
-
25
-
-
0032442795
-
Regulation of IL-17, IFN-gamma and IL-10 in human CD8(+) T cells by cyclic AMP-dependent signal transduction pathway
-
Shin HC, Benbernou N, Fekkar H, Esnault S, Guenounou M (1998) Regulation of IL-17, IFN-gamma and IL-10 in human CD8(+) T cells by cyclic AMP-dependent signal transduction pathway. Cytokine 10(11):841-850
-
(1998)
Cytokine
, vol.10
, Issue.11
, pp. 841-850
-
-
Shin, H.C.1
Benbernou, N.2
Fekkar, H.3
Esnault, S.4
Guenounou, M.5
-
26
-
-
73349098712
-
Infliximab treatment reduces the serum levels of interleukin-23 in patients with rheumatoid arthritis
-
doi:10.1007/s10165-009-0217-6
-
Kageyama Y, Kobayashi H, Kato N (2009) Infliximab treatment reduces the serum levels of interleukin-23 in patients with rheumatoid arthritis. Mod Rheumatol 19(6):657-662. doi: 10.1007/s10165-009-0217-6
-
(2009)
Mod Rheumatol
, vol.19
, Issue.6
, pp. 657-662
-
-
Kageyama, Y.1
Kobayashi, H.2
Kato, N.3
-
27
-
-
78449267111
-
The effects of adalimumab and methotrexate treatment on peripheral th17 cells and IL-17/IL-6 secretion in rheumatoid arthritis patients
-
doi:10.1007/s00296-009-1179-x
-
Yue C, You X, Zhao L, Wang H, Tang F, Zhang F et al (2010) The effects of adalimumab and methotrexate treatment on peripheral Th17 cells and IL-17/IL-6 secretion in rheumatoid arthritis patients. Rheumatol Int 30(12):1553-1557. doi:10.1007/s00296-009-1179-x
-
(2010)
Rheumatol Int
, vol.30
, Issue.12
, pp. 1553-1557
-
-
Yue, C.1
You, X.2
Zhao, L.3
Wang, H.4
Tang, F.5
Zhang, F.6
-
28
-
-
58349088074
-
Can clinical factors at presentation be used to predict outcome of treatment with methotrexate in patients with early inflammatory polyarthritis?
-
doi:10.1136/ard.2008.088237
-
Hider SL, Silman AJ, Thomson W, Lunt M, Bunn D, Symmons DP (2009) Can clinical factors at presentation be used to predict outcome of treatment with methotrexate in patients with early inflammatory polyarthritis? Ann Rheum Dis 68(1):57-62. doi: 10.1136/ard.2008.088237
-
(2009)
Ann Rheum Dis
, vol.68
, Issue.1
, pp. 57-62
-
-
Hider, S.L.1
Silman, A.J.2
Thomson, W.3
Lunt, M.4
Bunn, D.5
Symmons, D.P.6
-
29
-
-
77954428742
-
Predictors of clinical response and radiographic progression in patients with rheumatoid arthritis treated with methotrexate monotherapy
-
3e Initiative Group doi:10.3899/jrheum.090838
-
Drouin J, Haraoui B, 3e Initiative Group (2010) Predictors of clinical response and radiographic progression in patients with rheumatoid arthritis treated with methotrexate monotherapy. J Rheumatol 37(7):1405-1410. doi:10.3899/jrheum.090838
-
(2010)
J Rheumatol
, vol.37
, Issue.7
, pp. 1405-1410
-
-
Drouin, J.1
Haraoui, B.2
-
30
-
-
34447508090
-
A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis
-
doi:10.1002/art.22640
-
Wessels JA, van der Kooij SM, le Cessie S, Kievit W, Barerra P, Allaart CF et al (2007) A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis. Arthritis Rheum 56(6):1765-1775. doi: 10.1002/art.22640
-
(2007)
Arthritis Rheum
, vol.56
, Issue.6
, pp. 1765-1775
-
-
Wessels, J.A.1
Van Der Kooij, S.M.2
Le Cessie, S.3
Kievit, W.4
Barerra, P.5
Allaart, C.F.6
-
31
-
-
33751440574
-
Autoantibodies in rheumatoid arthritis: A review
-
doi:10.1016/j.biopha.2006.09.002
-
Mewar D, Wilson AG (2006) Autoantibodies in rheumatoid arthritis: a review. Biomed Pharmacother 60(10):648-655. doi: 10.1016/j.biopha.2006.09.002
-
(2006)
Biomed Pharmacother
, vol.60
, Issue.10
, pp. 648-655
-
-
Mewar, D.1
Wilson, A.G.2
-
32
-
-
0027514683
-
Function of B cells expressing a human immunoglobulin M rheumatoid factor autoantibody in transgenic mice
-
Tighe H, Chen PP, Tucker R, Kipps TJ, Roudier J, Jirik FR et al (1993) Function of B cells expressing a human immunoglobulin M rheumatoid factor autoantibody in transgenic mice. J Exp Med 177(1):109-118
-
(1993)
J Exp Med
, vol.177
, Issue.1
, pp. 109-118
-
-
Tighe, H.1
Chen, P.P.2
Tucker, R.3
Kipps, T.J.4
Roudier, J.5
Jirik, F.R.6
|