-
1
-
-
33744481750
-
Molecular pathogenesis of Fanconi anemia: Recent progress
-
Taniguchi T, D'Andrea AD. Molecular pathogenesis of Fanconi anemia: recent progress. Blood. 2006;107(11):4223-4233.
-
(2006)
Blood
, vol.107
, Issue.11
, pp. 4223-4233
-
-
Taniguchi, T.1
D'Andrea, A.D.2
-
2
-
-
72149119542
-
How the Fanconi anemia pathway guards the genome
-
Moldovan GL, D'Andrea AD. How the Fanconi anemia pathway guards the genome. Annu Rev Genet. 2009;43:223-249.
-
(2009)
Annu Rev Genet
, vol.43
, pp. 223-249
-
-
Moldovan, G.L.1
D'Andrea, A.D.2
-
3
-
-
0017118656
-
Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens
-
Auerbach AD, Wolman SR. Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens. Nature. 1976;261(5560):494-496.
-
(1976)
Nature
, vol.261
, Issue.5560
, pp. 494-496
-
-
Auerbach, A.D.1
Wolman, S.R.2
-
4
-
-
0035105291
-
Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway
-
Garcia-Higuera I, Taniguchi T, Ganesan S, et al. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol Cell. 2001;7(2):249-262.
-
(2001)
Mol Cell
, vol.7
, Issue.2
, pp. 249-262
-
-
Garcia-Higuera, I.1
Taniguchi, T.2
Ganesan, S.3
-
5
-
-
0036785375
-
S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51
-
Taniguchi T, Garcia-Higuera I, Andreassen PR, Gregory RC, Grompe M, D'Andrea AD. S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood. 2002;100(7):2414-2420.
-
(2002)
Blood
, vol.100
, Issue.7
, pp. 2414-2420
-
-
Taniguchi, T.1
Garcia-Higuera, I.2
Andreassen, P.R.3
Gregory, R.C.4
Grompe, M.5
D'Andrea, A.D.6
-
6
-
-
34249281152
-
FANCI is a second monoubiquitinated member of the Fanconi anemia pathway
-
Sims AE, Spiteri E, Sims RJ 3rd, et al. FANCI is a second monoubiquitinated member of the Fanconi anemia pathway. Nat Struct Mol Biol. 2007;14(6):564-567.
-
(2007)
Nat Struct Mol Biol
, vol.14
, Issue.6
, pp. 564-567
-
-
Sims, A.E.1
Spiteri, E.2
Sims III, R.J.3
-
7
-
-
34247110291
-
Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair
-
Smogorzewska A, Matsuoka S, Vinciguerra P, et al. Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair. Cell. 2007;129(2):289-301.
-
(2007)
Cell
, vol.129
, Issue.2
, pp. 289-301
-
-
Smogorzewska, A.1
Matsuoka, S.2
Vinciguerra, P.3
-
8
-
-
80052747469
-
Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway
-
Hodson C, Cole AR, Lewis LP, Miles JA, Purkiss A, Walden H. Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway. J Biol Chem. 2011;286(37):32628-32637.
-
(2011)
J Biol Chem
, vol.286
, Issue.37
, pp. 32628-32637
-
-
Hodson, C.1
Cole, A.R.2
Lewis, L.P.3
Miles, J.A.4
Purkiss, A.5
Walden, H.6
-
9
-
-
33746957852
-
UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation
-
Machida YJ, Machida Y, Chen Y, et al. UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation. Mol Cell. 2006;23(4):589-596.
-
(2006)
Mol Cell
, vol.23
, Issue.4
, pp. 589-596
-
-
Machida, Y.J.1
Machida, Y.2
Chen, Y.3
-
10
-
-
0141484612
-
A novel ubiquitin ligase is deficient in Fanconi anemia
-
Meetei AR, de Winter JP, Medhurst AL, et al. A novel ubiquitin ligase is deficient in Fanconi anemia. Nat Genet. 2003;35(2):165-170.
-
(2003)
Nat Genet
, vol.35
, Issue.2
, pp. 165-170
-
-
Meetei, A.R.1
De Winter, J.P.2
Medhurst, A.L.3
-
11
-
-
2942705849
-
Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin
-
Wang X, Andreassen PR, D'Andrea AD. Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Mol Cell Biol. 2004;24(13):5850-5862.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.13
, pp. 5850-5862
-
-
Wang, X.1
Andreassen, P.R.2
D'Andrea, A.D.3
-
12
-
-
36749082959
-
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway
-
Cohn MA, Kowal P, Yang K, et al. A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway. Mol Cell. 2007;28(5):786-797.
-
(2007)
Mol Cell
, vol.28
, Issue.5
, pp. 786-797
-
-
Cohn, M.A.1
Kowal, P.2
Yang, K.3
-
13
-
-
13244291457
-
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway
-
Nijman SM, Huang TT, Dirac AM, et al. The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol Cell. 2005;17(3):331-339.
-
(2005)
Mol Cell
, vol.17
, Issue.3
, pp. 331-339
-
-
Nijman, S.M.1
Huang, T.T.2
Dirac, A.M.3
-
14
-
-
79957904161
-
FANCP/SLX4: A Swiss army knife of DNA interstrand crosslink repair
-
Cybulski KE, Howlett NG. FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair. Cell Cycle. 2011;10(11):1757-1763.
-
(2011)
Cell Cycle
, vol.10
, Issue.11
, pp. 1757-1763
-
-
Cybulski, K.E.1
Howlett, N.G.2
-
15
-
-
79251611165
-
Mutations of the SLX4 gene in Fanconi anemia
-
Kim Y, Lach FP, Desetty R, Hanenberg H, Auerbach AD, Smogorzewska A. Mutations of the SLX4 gene in Fanconi anemia. Nat Genet. 2011;43(2):142-146.
-
(2011)
Nat Genet
, vol.43
, Issue.2
, pp. 142-146
-
-
Kim, Y.1
Lach, F.P.2
Desetty, R.3
Hanenberg, H.4
Auerbach, A.D.5
Smogorzewska, A.6
-
16
-
-
77954279611
-
Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents
-
Kratz K, Schopf B, Kaden S, et al. Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents. Cell. 2010;142(1):77-88.
-
(2010)
Cell
, vol.142
, Issue.1
, pp. 77-88
-
-
Kratz, K.1
Schopf, B.2
Kaden, S.3
-
17
-
-
77954274685
-
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2
-
MacKay C, Declais AC, Lundin C, et al. Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2. Cell. 2010;142(1):65-76.
-
(2010)
Cell
, vol.142
, Issue.1
, pp. 65-76
-
-
MacKay, C.1
Declais, A.C.2
Lundin, C.3
-
18
-
-
77954286076
-
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair
-
Smogorzewska A, Desetty R, Saito TT, et al. A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. Mol Cell. 2010;39(1):36-47.
-
(2010)
Mol Cell
, vol.39
, Issue.1
, pp. 36-47
-
-
Smogorzewska, A.1
Desetty, R.2
Saito, T.T.3
-
19
-
-
79251632658
-
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype
-
Stoepker C, Hain K, Schuster B, et al. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet. 2011;43(2):138-141.
-
(2011)
Nat Genet
, vol.43
, Issue.2
, pp. 138-141
-
-
Stoepker, C.1
Hain, K.2
Schuster, B.3
-
20
-
-
63049096813
-
Ubiquitin-binding domains and their role in the DNA damage response
-
Hofmann K. Ubiquitin-binding domains and their role in the DNA damage response. DNA Repair (Amst). 2009;8(4):544-556.
-
(2009)
DNA Repair (Amst)
, vol.8
, Issue.4
, pp. 544-556
-
-
Hofmann, K.1
-
22
-
-
0034667598
-
Proteins of the endoplasmic-reticulum-associated degradation pathway: Domain detection and function prediction
-
Ponting CP. Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction. Biochem J. 2000;351(Pt 2):527-535.
-
(2000)
Biochem J
, vol.351
, Issue.PART 2
, pp. 527-535
-
-
Ponting, C.P.1
-
23
-
-
0345616428
-
A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain
-
Shih SC, Prag G, Francis SA, Sutanto MA, Hurley JH, Hicke L. A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. EMBO J. 2003;22(6):1273-1281.
-
(2003)
EMBO J
, vol.22
, Issue.6
, pp. 1273-1281
-
-
Shih, S.C.1
Prag, G.2
Francis, S.A.3
Sutanto, M.A.4
Hurley, J.H.5
Hicke, L.6
-
24
-
-
75949122886
-
Regulation of translesion synthesis DNA polymerase eta by monoubiquitination
-
Bienko M, Green CM, Sabbioneda S, et al. Regulation of translesion synthesis DNA polymerase eta by monoubiquitination. Mol Cell. 2010;37(3):396-407.
-
(2010)
Mol Cell
, vol.37
, Issue.3
, pp. 396-407
-
-
Bienko, M.1
Green, C.M.2
Sabbioneda, S.3
-
25
-
-
0029862497
-
A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
-
Ory DS, Neugeboren BA, Mulligan RC. A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc Natl Acad Sci U S A. 1996;93(21):11400-11406.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, Issue.21
, pp. 11400-11406
-
-
Ory, D.S.1
Neugeboren, B.A.2
Mulligan, R.C.3
-
26
-
-
0031657241
-
Functional activity of the Fanconi anemia protein FAA requires FAC binding and nuclear localization
-
Näf D, Kupfer GM, Suliman A, Lambert K, D'Andrea AD. Functional activity of the Fanconi anemia protein FAA requires FAC binding and nuclear localization. Mol Cell Biol. 1998;18(10):5952-5960.
-
(1998)
Mol Cell Biol
, vol.18
, Issue.10
, pp. 5952-5960
-
-
Näf, D.1
Kupfer, G.M.2
Suliman, A.3
Lambert, K.4
D'Andrea, A.D.5
-
27
-
-
0036786873
-
The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC
-
Taniguchi T, D'Andrea AD. The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC. Blood. 2002;100(7):2457-2462.
-
(2002)
Blood
, vol.100
, Issue.7
, pp. 2457-2462
-
-
Taniguchi, T.1
D'Andrea, A.D.2
-
28
-
-
3242712112
-
BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function
-
Arlt MF, Xu B, Durkin SG, Casper AM, Kastan MB, Glover TW. BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function. Mol Cell Biol. 2004;24(15):6701-6709.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.15
, pp. 6701-6709
-
-
Arlt, M.F.1
Xu, B.2
Durkin, S.G.3
Casper, A.M.4
Kastan, M.B.5
Glover, T.W.6
-
29
-
-
70350365400
-
Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif
-
Howlett NG, Harney JA, Rego MA, Kolling FW, Glover TW. Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif. J Biol Chem. 2009;284(42):28935-28942.
-
(2009)
J Biol Chem
, vol.284
, Issue.42
, pp. 28935-28942
-
-
Howlett, N.G.1
Harney, J.A.2
Rego, M.A.3
Kolling, F.W.4
Glover, T.W.5
-
30
-
-
17444397116
-
Porter: A new, accurate server for protein secondary structure prediction
-
Pollastri G, McLysaght A. Porter: a new, accurate server for protein secondary structure prediction. Bioinformatics. 2005;21(8):1719-1720.
-
(2005)
Bioinformatics
, vol.21
, Issue.8
, pp. 1719-1720
-
-
Pollastri, G.1
McLysaght, A.2
-
31
-
-
0038820381
-
Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding
-
Kang RS, Daniels CM, Francis SA, et al. Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding. Cell. 2003;113(5):621-630.
-
(2003)
Cell
, vol.113
, Issue.5
, pp. 621-630
-
-
Kang, R.S.1
Daniels, C.M.2
Francis, S.A.3
-
32
-
-
79960539404
-
Structure of the FANCI-FANCD2 complex: Insights into the Fanconi anemia DNA repair pathway
-
Joo W, Xu G, Persky NS, et al. Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway. Science. 2011;333(6040):312-316.
-
(2011)
Science
, vol.333
, Issue.6040
, pp. 312-316
-
-
Joo, W.1
Xu, G.2
Persky, N.S.3
-
33
-
-
12844263398
-
Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin
-
Montes de Oca R, Andreassen PR, Margossian SP, et al. Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin. Blood. 2005;105(3):1003-1009.
-
(2005)
Blood
, vol.105
, Issue.3
, pp. 1003-1009
-
-
Montes De Oca, R.1
Andreassen, P.R.2
Margossian, S.P.3
-
34
-
-
34247576595
-
Hypomorphic mutations in the gene encoding a key Fanconi anemia protein, FANCD2, sustain a significant group of FA-D2 patients with severe phenotype
-
Kalb R, Neveling K, Hoehn H, et al. Hypomorphic mutations in the gene encoding a key Fanconi anemia protein, FANCD2, sustain a significant group of FA-D2 patients with severe phenotype. Am J Hum Genet. 2007;80(5):895-910.
-
(2007)
Am J Hum Genet
, vol.80
, Issue.5
, pp. 895-910
-
-
Kalb, R.1
Neveling, K.2
Hoehn, H.3
-
35
-
-
29144499065
-
Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis
-
Bienko M, Green CM, Crosetto N, et al. Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. Science. 2005;310(5755):1821-1824.
-
(2005)
Science
, vol.310
, Issue.5755
, pp. 1821-1824
-
-
Bienko, M.1
Green, C.M.2
Crosetto, N.3
-
36
-
-
79955580794
-
Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway
-
Yamamoto KN, Kobayashi S, Tsuda M, et al. Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway. Proc Natl Acad Sci U S A. 2011;108(16):6492-6496.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.16
, pp. 6492-6496
-
-
Yamamoto, K.N.1
Kobayashi, S.2
Tsuda, M.3
-
37
-
-
84863350996
-
Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair
-
Leung JW, Wang Y, Fong KW, Huen MS, Li L, Chen J. Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair. Proc Natl Acad Sci U S A. 2012;109(12):4491-4496.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.12
, pp. 4491-4496
-
-
Leung, J.W.1
Wang, Y.2
Fong, K.W.3
Huen, M.S.4
Li, L.5
Chen, J.6
-
38
-
-
84859564894
-
FAAP20: A novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway
-
Ali AM, Pradhan A, Singh TR, et al. FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway. Blood. 2012;119(14):3285-3294.
-
(2012)
Blood
, vol.119
, Issue.14
, pp. 3285-3294
-
-
Ali, A.M.1
Pradhan, A.2
Singh, T.R.3
-
39
-
-
84862777927
-
Regulation of Rev1 by the Fanconi anemia core complex
-
Kim H, Yang K, Dejsuphong D, D'Andrea AD. Regulation of Rev1 by the Fanconi anemia core complex. Nat Struct Mol Biol. 2012;19(2):164-170.
-
(2012)
Nat Struct Mol Biol
, vol.19
, Issue.2
, pp. 164-170
-
-
Kim, H.1
Yang, K.2
Dejsuphong, D.3
D'Andrea, A.D.4
-
40
-
-
57749112131
-
Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI
-
Alpi AF, Pace PE, Babu MM, Patel KJ. Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI. Mol Cell. 2008;32(6):767-777.
-
(2008)
Mol Cell
, vol.32
, Issue.6
, pp. 767-777
-
-
Alpi, A.F.1
Pace, P.E.2
Babu, M.M.3
Patel, K.J.4
|