The influence of delayed compressive stress on TGF-β1-induced chondrogenic differentiation of rat BMSCs through Smad-dependent and Smad-independent pathways

Biomaterials

Volumn 33, Issue 33, 2012, Pages 8395-8405

  Li, Juan ^a   Wang, Jun ^a   Zou, Yuanwen ^b   Zhang, Yifan ^a   Long, Dan ^c   Lei, Lei ^a   Tan, Lijun ^a   Ye, Rui ^a   Wang, Xuejin ^c   Zhao, Zhihe ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c SICHUAN UNIVERSITY   (China)

Author keywords

Alginate; Chondrogenesis; Delayed loading; Mesenchymal stem cells; Transforming growth factor

Indexed keywords

CHONDROGENESIS; CHONDROGENIC; CHONDROGENIC DIFFERENTIATION; GENE TRANSCRIPTIONS; MECHANICAL STIMULATION; MECHANICAL STIMULUS; MECHANICAL STRESS; MESENCHYMAL STEM CELL; NUCLEAR TRANSLOCATIONS; PROTEIN EXPRESSIONS; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; STRESS-INDUCED; TRANSFORMING GROWTH FACTORS;

ALGINATE; CARTILAGE; CELL CULTURE; GENES; PHOSPHORYLATION; TRANSCRIPTION;

COMPRESSIVE STRESS;

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN; MITOGEN ACTIVATED PROTEIN KINASE 3; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SYNAPTOPHYSIN; TRANSFORMING GROWTH FACTOR BETA1; WNT7A PROTEIN;

ANIMAL CELL; ARTICLE; BONE MARROW DERIVED MESENCHYMAL STROMAL CELL; CARTILAGE CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL STRUCTURE; CHONDROGENESIS; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; MECHANICAL STIMULATION; MECHANICAL STRESS; MESENCHYMAL STROMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BENZAMIDES; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; DIOXOLES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RABBITS; SIGNAL TRANSDUCTION; SMAD PROTEINS, RECEPTOR-REGULATED; STRESS, MECHANICAL; TISSUE SCAFFOLDS; TRANSFORMING GROWTH FACTOR BETA1;

RATTUS;

EID: 84866165740     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.08.019     Document Type: Article

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