Mechanical load modulates chondrogenesis of human mesenchymal stem cells through the TGF-β pathway

Journal of Cellular and Molecular Medicine

Volumn 14, Issue 6 A, 2010, Pages 1338-1346

  Li, Zhen ^a,b   Kupcsik, Laszlo ^a,c   Yao, Shan Jing ^b   Alini, Mauro ^a   Stoddart, Martin J ^a  

^a AO RESEARCH INSTITUTE   (Switzerland)

^b ZHEJIANG UNIVERSITY   (China)

^c EÖTVÖS LORÁND UNIVERSITY   (Hungary)

Author keywords

Chondrogenesis; Fibrin polyurethane scaffold composites; Human bone marrow mesenchymal stem cells; Mechanical load; TGF pathway; TGF 1

Indexed keywords

DNA; GLYCOSAMINOGLYCAN; PROTEIN SERINE THREONINE KINASE; TGF BETA TYPE I RECEPTOR; TGF-BETA TYPE I RECEPTOR; TISSUE SCAFFOLD; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA3; CULTURE MEDIUM;

ARTICLE; CELL CULTURE; CHONDROGENESIS; CULTURE MEDIUM; DRUG ANTAGONISM; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MECHANICAL STRESS; MESENCHYMAL STEM CELL; METABOLISM; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; MESENCHYMAL STROMA CELL; PHARMACOLOGY; TISSUE SCAFFOLD;

CELLS, CULTURED; CHONDROGENESIS; CULTURE MEDIA, CONDITIONED; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GLYCOSAMINOGLYCANS; HUMANS; MESENCHYMAL STEM CELLS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; TISSUE SCAFFOLDS; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA3; MESENCHYMAL STROMAL CELLS;

EID: 77955162737     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2009.00780.x     Document Type: Article

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