메뉴 건너뛰기




Volumn 86, Issue 17, 2012, Pages 9163-9174

Impact of VP1-specific protein sequence motifs on adeno-associated virus type 2 intracellular trafficking and nuclear entry

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOLIPASE A2; PROTEIN VP1; PROTEIN VP2;

EID: 84866152302     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00282-12     Document Type: Article
Times cited : (79)

References (64)
  • 1
    • 33748945422 scopus 로고    scopus 로고
    • The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9
    • Akache B, et al. 2006. The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9. J. Virol. 80:9831-9836.
    • (2006) J. Virol , vol.80 , pp. 9831-9836
    • Akache, B.1
  • 2
    • 33846324384 scopus 로고    scopus 로고
    • A two-hybrid screen identifies cathepsins B and L as uncoating factors for adeno-associated virus 2 and 8
    • Akache B, et al. 2007. A two-hybrid screen identifies cathepsins B and L as uncoating factors for adeno-associated virus 2 and 8. Mol. Ther. 15:330-339.
    • (2007) Mol. Ther , vol.15 , pp. 330-339
    • Akache, B.1
  • 3
    • 48849108965 scopus 로고    scopus 로고
    • Subcellular fractionation of tissue culture cells. Current Protoc
    • Chapter 4:Unit 4.3
    • Aniento F, Gruenberg J. 2004. Subcellular fractionation of tissue culture cells. Current Protoc. Protein Sci. Chapter 4:Unit 4.3.
    • (2004) Protein Sci
    • Aniento, F.1    Gruenberg, J.2
  • 4
    • 33748494015 scopus 로고    scopus 로고
    • Adeno-associated virus type 2 contains an integrin α5β1 binding domain essential for viral cell entry
    • Asokan A, Hamra JB, Govindasamy L, Agbandje-McKenna M, Samulski RJ. 2006. Adeno-associated virus type 2 contains an integrin α5β1 binding domain essential for viral cell entry. J. Virol. 80:8961-8969.
    • (2006) J. Virol , vol.80 , pp. 8961-8969
    • Asokan, A.1    Hamra, J.B.2    Govindasamy, L.3    Agbandje-McKenna, M.4    Samulski, R.J.5
  • 5
    • 0033998692 scopus 로고    scopus 로고
    • Infectious entry pathway of adeno-associated virus and adeno-associated virus vectors
    • Bartlett JS, Wilcher R, Samulski RJ. 2000. Infectious entry pathway of adeno-associated virus and adeno-associated virus vectors. J. Virol. 74:2777-2785.
    • (2000) J. Virol , vol.74 , pp. 2777-2785
    • Bartlett, J.S.1    Wilcher, R.2    Samulski, R.J.3
  • 6
    • 13444310872 scopus 로고    scopus 로고
    • Mutational analysis of narrow pores at the fivefold symmetry axes of adeno-associated virus type 2 capsids reveals a dual role in genome packaging and activation of phospholipase A2 activity
    • Bleker S, Sonntag F, Kleinschmidt JA. 2005. Mutational analysis of narrow pores at the fivefold symmetry axes of adeno-associated virus type 2 capsids reveals a dual role in genome packaging and activation of phospholipase A2 activity. J. Virol. 79:2528-2540.
    • (2005) J. Virol , vol.79 , pp. 2528-2540
    • Bleker, S.1    Sonntag, F.2    Kleinschmidt, J.A.3
  • 7
    • 33750279611 scopus 로고    scopus 로고
    • Parvoviral nuclear import: bypassing the host nuclear-transport machinery
    • Cohen S, Behzad AR, Carroll JB, Pante N. 2006. Parvoviral nuclear import: bypassing the host nuclear-transport machinery. J. Gen. Virol. 87:3209-3213.
    • (2006) J. Gen. Virol , vol.87 , pp. 3209-3213
    • Cohen, S.1    Behzad, A.R.2    Carroll, J.B.3    Pante, N.4
  • 8
    • 79955440194 scopus 로고    scopus 로고
    • Nuclear envelope disruption involving host caspases plays a role in the parvovirus replication cycle
    • Cohen S, Marr AK, Garcin P, Pante N. 2011. Nuclear envelope disruption involving host caspases plays a role in the parvovirus replication cycle. J. Virol. 85:4863-4874.
    • (2011) J. Virol , vol.85 , pp. 4863-4874
    • Cohen, S.1    Marr, A.K.2    Garcin, P.3    Pante, N.4
  • 9
    • 28044462666 scopus 로고    scopus 로고
    • Pushing the envelope: microinjection of Minute virus of mice into Xenopus oocytes causes damage to the nuclear envelope
    • Cohen S, Pante N. 2005. Pushing the envelope: microinjection of Minute virus of mice into Xenopus oocytes causes damage to the nuclear envelope. J. Gen. Virol. 86:3243-3252.
    • (2005) J. Gen. Virol , vol.86 , pp. 3243-3252
    • Cohen, S.1    Pante, N.2
  • 10
    • 54249126862 scopus 로고    scopus 로고
    • Gene therapy using adeno-associated virus vectors
    • Daya S, Berns KI. 2008. Gene therapy using adeno-associated virus vectors. Clin. Microbiol. Rev. 21:583-593.
    • (2008) Clin. Microbiol. Rev , vol.21 , pp. 583-593
    • Daya, S.1    Berns, K.I.2
  • 11
    • 20744433079 scopus 로고    scopus 로고
    • Intracellular trafficking of adeno-associated viral vectors
    • Ding W, Zhang L, Yan Z, Engelhardt JF. 2005. Intracellular trafficking of adeno-associated viral vectors. Gene Ther. 12:873-880.
    • (2005) Gene Ther , vol.12 , pp. 873-880
    • Ding, W.1    Zhang, L.2    Yan, Z.3    Engelhardt, J.F.4
  • 12
    • 33645522130 scopus 로고    scopus 로고
    • rAAV2 traffics through both the late and the recycling endosomes in a dose-dependent fashion
    • Ding W, Zhang LN, Yeaman C, Engelhardt JF. 2006. rAAV2 traffics through both the late and the recycling endosomes in a dose-dependent fashion. Mol. Ther. 13:671-682.
    • (2006) Mol. Ther , vol.13 , pp. 671-682
    • Ding, W.1    Zhang, L.N.2    Yeaman, C.3    Engelhardt, J.F.4
  • 13
    • 0035138205 scopus 로고    scopus 로고
    • Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradation
    • Douar AM, Poulard K, Stockholm D, Danos O. 2001. Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradation. J. Virol. 75:1824-1833.
    • (2001) J. Virol , vol.75 , pp. 1824-1833
    • Douar, A.M.1    Poulard, K.2    Stockholm, D.3    Danos, O.4
  • 14
    • 0032737034 scopus 로고    scopus 로고
    • Dynamin is required for recombinant adenoassociated virus type 2 infection
    • Duan D, et al. 1999. Dynamin is required for recombinant adenoassociated virus type 2 infection. J. Virol. 73:10371-10376.
    • (1999) J. Virol , vol.73 , pp. 10371-10376
    • Duan, D.1
  • 15
    • 0034091579 scopus 로고    scopus 로고
    • Endosomal processing limits gene transfer to polarized airway epithelia by adenoassociated virus
    • Duan D, Yue Y, Yan Z, Yang J, Engelhardt JF. 2000. Endosomal processing limits gene transfer to polarized airway epithelia by adenoassociated virus. J. Clin. Invest. 105:1573-1587.
    • (2000) J. Clin. Invest , vol.105 , pp. 1573-1587
    • Duan, D.1    Yue, Y.2    Yan, Z.3    Yang, J.4    Engelhardt, J.F.5
  • 16
    • 28044448698 scopus 로고    scopus 로고
    • Parvoviral virions deploy a capsid-tethered lipolytic enzyme to breach the endosomal membrane during cell entry
    • Farr GA, Zhang LG, Tattersall P. 2005. Parvoviral virions deploy a capsid-tethered lipolytic enzyme to breach the endosomal membrane during cell entry. Proc. Natl. Acad. Sci. U. S. A. 102:17148-17153.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 17148-17153
    • Farr, G.A.1    Zhang, L.G.2    Tattersall, P.3
  • 17
    • 0036246727 scopus 로고    scopus 로고
    • The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity
    • Girod A, et al. 2002. The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity. J. Gen. Virol. 83:973-978.
    • (2002) J. Gen. Virol , vol.83 , pp. 973-978
    • Girod, A.1
  • 18
  • 19
    • 33646719922 scopus 로고    scopus 로고
    • Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assembly
    • Grieger JC, Snowdy S, Samulski RJ. 2006. Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assembly. J. Virol. 80:5199-5210.
    • (2006) J. Virol , vol.80 , pp. 5199-5210
    • Grieger, J.C.1    Snowdy, S.2    Samulski, R.J.3
  • 20
    • 0032773889 scopus 로고    scopus 로고
    • Titration of AAV-2 particles via a novel capsid ELISA: packaging of genomes can limit production of recombinant AAV-2
    • Grimm D, et al. 1999. Titration of AAV-2 particles via a novel capsid ELISA: packaging of genomes can limit production of recombinant AAV-2. Gene Ther. 6:1322-1330.
    • (1999) Gene Ther , vol.6 , pp. 1322-1330
    • Grimm, D.1
  • 21
    • 0033987571 scopus 로고    scopus 로고
    • Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblasts
    • Hansen J, Qing K, Kwon HJ, Mah C, Srivastava A. 2000. Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblasts. J. Virol. 74:992-996.
    • (2000) J. Virol , vol.74 , pp. 992-996
    • Hansen, J.1    Qing, K.2    Kwon, H.J.3    Mah, C.4    Srivastava, A.5
  • 22
    • 0035043237 scopus 로고    scopus 로고
    • Adeno-associated virus type 2-mediated gene transfer: altered endocytic processing enhances transduction efficiency in murine fibroblasts
    • Hansen J, Qing K, Srivastava A. 2001. Adeno-associated virus type 2-mediated gene transfer: altered endocytic processing enhances transduction efficiency in murine fibroblasts. J. Virol. 75:4080-4090.
    • (2001) J. Virol , vol.75 , pp. 4080-4090
    • Hansen, J.1    Qing, K.2    Srivastava, A.3
  • 23
    • 0034759535 scopus 로고    scopus 로고
    • Infection of purified nuclei by adeno-associated virus 2
    • Hansen J, Qing K, Srivastava A. 2001. Infection of purified nuclei by adeno-associated virus 2. Mol. Ther. 4:289-296.
    • (2001) Mol. Ther , vol.4 , pp. 289-296
    • Hansen, J.1    Qing, K.2    Srivastava, A.3
  • 24
    • 0034740693 scopus 로고    scopus 로고
    • Mechanism and role of PDZ domains in signaling complex assembly
    • Harris BZ, Lim WA. 2001. Mechanism and role of PDZ domains in signaling complex assembly. J. Cell Sci. 114:3219-3231.
    • (2001) J. Cell Sci , vol.114 , pp. 3219-3231
    • Harris, B.Z.1    Lim, W.A.2
  • 25
    • 10044222300 scopus 로고    scopus 로고
    • Intracellular viral processing, not single-stranded DNA accumulation, is crucial for recombinant adenoassociated virus transduction
    • Hauck B, Zhao W, High K, Xiao W. 2004. Intracellular viral processing, not single-stranded DNA accumulation, is crucial for recombinant adenoassociated virus transduction. J. Virol. 78:13678-13686.
    • (2004) J. Virol , vol.78 , pp. 13678-13686
    • Hauck, B.1    Zhao, W.2    High, K.3    Xiao, W.4
  • 26
    • 0025299743 scopus 로고
    • The adenoassociated virus rep gene suppresses herpes simplex virus-induced DNA amplification
    • Heilbronn R, Burkle A, Stephan S, Hausen H. 1990. The adenoassociated virus rep gene suppresses herpes simplex virus-induced DNA amplification. J. Virol. 64:3012-3018.
    • (1990) J. Virol , vol.64 , pp. 3012-3018
    • Heilbronn, R.1    Burkle, A.2    Stephan, S.3    Hausen, H.4
  • 27
    • 0032816003 scopus 로고    scopus 로고
    • Nuclear transport of the major capsid protein is essential for adeno-associated virus capsid formation
    • Hoque M, et al. 1999. Nuclear transport of the major capsid protein is essential for adeno-associated virus capsid formation. J. Virol. 73:7912-7915.
    • (1999) J. Virol , vol.73 , pp. 7912-7915
    • Hoque, M.1
  • 28
    • 80655143495 scopus 로고    scopus 로고
    • Emerging theme: cellular PDZ proteins as common targets of pathogenic viruses
    • Javier RT, Rice AP. 2011. Emerging theme: cellular PDZ proteins as common targets of pathogenic viruses. J. Virol. 85:11544-11556.
    • (2011) J. Virol , vol.85 , pp. 11544-11556
    • Javier, R.T.1    Rice, A.P.2
  • 29
    • 77956627896 scopus 로고    scopus 로고
    • Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction
    • Johnson JS, et al. 2010. Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction. J. Virol. 84:8888-8902.
    • (2010) J. Virol , vol.84 , pp. 8888-8902
    • Johnson, J.S.1
  • 30
    • 62749167014 scopus 로고    scopus 로고
    • Enhancement of adeno-associated virus infection by mobilizing capsids into and out of the nucleolus
    • Johnson JS, Samulski RJ. 2009. Enhancement of adeno-associated virus infection by mobilizing capsids into and out of the nucleolus. J. Virol. 83:2632-2644.
    • (2009) J. Virol , vol.83 , pp. 2632-2644
    • Johnson, J.S.1    Samulski, R.J.2
  • 31
    • 10644225886 scopus 로고    scopus 로고
    • Hepatocyte growth factor receptor is a coreceptor for adeno-associated virus type 2 infection
    • Kashiwakura Y, et al. 2005. Hepatocyte growth factor receptor is a coreceptor for adeno-associated virus type 2 infection. J. Virol. 79:609-614.
    • (2005) J. Virol , vol.79 , pp. 609-614
    • Kashiwakura, Y.1
  • 32
    • 0141454787 scopus 로고    scopus 로고
    • Identification of a heparin-binding motif on adeno-associated virus type 2 capsids
    • Kern A, et al. 2003. Identification of a heparin-binding motif on adeno-associated virus type 2 capsids. J. Virol. 77:11072-11081.
    • (2003) J. Virol , vol.77 , pp. 11072-11081
    • Kern, A.1
  • 33
    • 0037200109 scopus 로고    scopus 로고
    • Separation and characterization of late endosomal membrane domains
    • Kobayashi T, et al. 2002. Separation and characterization of late endosomal membrane domains. J. Biol. Chem. 277:32157-32164.
    • (2002) J. Biol. Chem , vol.277 , pp. 32157-32164
    • Kobayashi, T.1
  • 34
    • 17444405970 scopus 로고    scopus 로고
    • A conformational change in the adeno-associated virus type 2 capsid leads to the exposure of hidden VP1 N termini
    • Kronenberg S, Bottcher B, von der Lieth CW, Bleker S, Kleinschmidt JA. 2005. A conformational change in the adeno-associated virus type 2 capsid leads to the exposure of hidden VP1 N termini. J. Virol. 79:5296-5303.
    • (2005) J. Virol , vol.79 , pp. 5296-5303
    • Kronenberg, S.1    Bottcher, B.2    von der Lieth, C.W.3    Bleker, S.4    Kleinschmidt, J.A.5
  • 35
    • 0020788648 scopus 로고
    • Cloning of infectious adeno-associated virus genomes in bacterial plasmids
    • Laughlin CA, Tratschin JD, Coon H, Carter BJ. 1983. Cloning of infectious adeno-associated virus genomes in bacterial plasmids. Gene 23:65-73.
    • (1983) Gene , vol.23 , pp. 65-73
    • Laughlin, C.A.1    Tratschin, J.D.2    Coon, H.3    Carter, B.J.4
  • 36
    • 27744497012 scopus 로고    scopus 로고
    • Adeno-associated virus vectors: potential applications for cancer gene therapy
    • Li C, Bowles DE, van Dyke T, Samulski RJ. 2005. Adeno-associated virus vectors: potential applications for cancer gene therapy. Cancer Gene Ther. 12:913-925.
    • (2005) Cancer Gene Ther , vol.12 , pp. 913-925
    • Li, C.1    Bowles, D.E.2    van Dyke, T.3    Samulski, R.J.4
  • 37
    • 24644509652 scopus 로고    scopus 로고
    • Green fluorescent protein-tagged adeno-associated virus particles allow the study of cytosolic and nuclear trafficking
    • Lux K, et al. 2005. Green fluorescent protein-tagged adeno-associated virus particles allow the study of cytosolic and nuclear trafficking. J. Virol. 79:11776-11787.
    • (2005) J. Virol , vol.79 , pp. 11776-11787
    • Lux, K.1
  • 38
    • 44049094771 scopus 로고    scopus 로고
    • Clinical gene therapy using recombinant adeno-associated virus vectors
    • Mueller C, Flotte TR. 2008. Clinical gene therapy using recombinant adeno-associated virus vectors. Gene Ther. 15:858-863.
    • (2008) Gene Ther , vol.15 , pp. 858-863
    • Mueller, C.1    Flotte, T.R.2
  • 39
    • 0001142644 scopus 로고    scopus 로고
    • Parvoviridae: the viruses and their replication
    • Knipe DM, Howley PM, 4th ed. Lippincott/The Williams & Wilkins Co, New York, NY.
    • Muzyczka N, Berns KI. 2001. Parvoviridae: the viruses and their replication, p 2327-2360. In Knipe DM, Howley PM(ed), Fields virology, 4th ed. Lippincott/The Williams & Wilkins Co, New York, NY.
    • (2001) Fields virology , pp. 2327-2360
    • Muzyczka, N.1    Berns, K.I.2
  • 40
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini L, et al. 1996. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272:263-267.
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1
  • 41
    • 73449107465 scopus 로고    scopus 로고
    • Combined prophylactic and therapeutic intranasal vaccination against human papillomavirus type-16 using different adenoassociated virus serotype vectors
    • Nieto K, et al. 2009. Combined prophylactic and therapeutic intranasal vaccination against human papillomavirus type-16 using different adenoassociated virus serotype vectors. Antivir. Ther. 14:1125-1137.
    • (2009) Antivir. Ther , vol.14 , pp. 1125-1137
    • Nieto, K.1
  • 42
    • 83655164541 scopus 로고    scopus 로고
    • Adeno-associated virus 2 infection requires endocytosis through the CLIC/GEEC pathway
    • Nonnenmacher M, Weber T. 2011. Adeno-associated virus 2 infection requires endocytosis through the CLIC/GEEC pathway. Cell Host Microbe 10:563-576.
    • (2011) Cell Host Microbe , vol.10 , pp. 563-576
    • Nonnenmacher, M.1    Weber, T.2
  • 44
    • 0036828063 scopus 로고    scopus 로고
    • Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells
    • Pajusola K, et al. 2002. Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells. J. Virol. 76:11530-11540.
    • (2002) J. Virol , vol.76 , pp. 11530-11540
    • Pajusola, K.1
  • 45
    • 77957312097 scopus 로고    scopus 로고
    • Structures and functions of parvovirus capsids and the process of cell infection
    • Parrish CR. 2010. Structures and functions of parvovirus capsids and the process of cell infection. Curr. Top. Microbiol. Immunol. 343:149-176.
    • (2010) Curr. Top. Microbiol. Immunol , vol.343 , pp. 149-176
    • Parrish, C.R.1
  • 46
    • 0033010884 scopus 로고    scopus 로고
    • Human fibroblast growth factor receptor 1 is a coreceptor for infection by adeno-associated virus 2
    • Qing K, et al. 1999. Human fibroblast growth factor receptor 1 is a coreceptor for infection by adeno-associated virus 2. Nat. Med. 5:71-77.
    • (1999) Nat. Med , vol.5 , pp. 71-77
    • Qing, K.1
  • 47
    • 0033799367 scopus 로고    scopus 로고
    • Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation
    • Sanlioglu S, et al. 2000. Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation. J. Virol. 74:9184-9196.
    • (2000) J. Virol , vol.74 , pp. 9184-9196
    • Sanlioglu, S.1
  • 48
    • 70849112486 scopus 로고    scopus 로고
    • Cell signaling in space and time: where proteins come together and when they're apart
    • Scott JD, Pawson T. 2009. Cell signaling in space and time: where proteins come together and when they're apart. Science 326:1220-1224.
    • (2009) Science , vol.326 , pp. 1220-1224
    • Scott, J.D.1    Pawson, T.2
  • 49
    • 0035976603 scopus 로고    scopus 로고
    • Real-time single-molecule imaging of the infection pathway of an adeno-associated virus
    • Seisenberger G, et al. 2001. Real-time single-molecule imaging of the infection pathway of an adeno-associated virus. Science 294:1929-1932.
    • (2001) Science , vol.294 , pp. 1929-1932
    • Seisenberger, G.1
  • 50
    • 33750712806 scopus 로고    scopus 로고
    • Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus
    • Sonntag F, Bleker S, Leuchs B, Fischer R, Kleinschmidt JA. 2006. Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus. J. Virol. 80:11040-11054.
    • (2006) J. Virol , vol.80 , pp. 11040-11054
    • Sonntag, F.1    Bleker, S.2    Leuchs, B.3    Fischer, R.4    Kleinschmidt, J.A.5
  • 51
    • 78649447518 scopus 로고    scopus 로고
    • Intrinsic phospholipase A2 activity of adeno-associated virus is involved in endosomal escape of incoming particles
    • Stahnke S, et al. 2011. Intrinsic phospholipase A2 activity of adeno-associated virus is involved in endosomal escape of incoming particles. Virology 409:77-83.
    • (2011) Virology , vol.409 , pp. 77-83
    • Stahnke, S.1
  • 52
    • 14844294424 scopus 로고    scopus 로고
    • Protein production by auto-induction in high-density shaking cultures
    • Studier FW. 2005. Protein production by auto-induction in high-density shaking cultures. Protein Expr. Purif. 41:207-234.
    • (2005) Protein Expr. Purif , vol.41 , pp. 207-234
    • Studier, F.W.1
  • 53
    • 0032589751 scopus 로고    scopus 로고
    • αvβ5 integrin: a coreceptor for adeno-associated virus type 2 infection
    • Summerford C, Bartlett JS, Samulski RJ. 1999. αvβ5 integrin: a coreceptor for adeno-associated virus type 2 infection. Nat. Med. 5:78-82.
    • (1999) Nat. Med , vol.5 , pp. 78-82
    • Summerford, C.1    Bartlett, J.S.2    Samulski, R.J.3
  • 54
    • 0031906147 scopus 로고    scopus 로고
    • Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions
    • Summerford C, Samulski RJ. 1998. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J. Virol. 72:1438-1445.
    • (1998) J. Virol , vol.72 , pp. 1438-1445
    • Summerford, C.1    Samulski, R.J.2
  • 55
    • 62549159967 scopus 로고    scopus 로고
    • Tailoring the AAV vector capsid for gene therapy
    • Vandenberghe LH, Wilson JM, Gao G. 2009. Tailoring the AAV vector capsid for gene therapy. Gene Ther. 16:311-319.
    • (2009) Gene Ther , vol.16 , pp. 311-319
    • Vandenberghe, L.H.1    Wilson, J.M.2    Gao, G.3
  • 56
    • 0036664426 scopus 로고    scopus 로고
    • Development and optimization of a real-time quantitative PCR-based method for the titration of AAV-2 vector stocks
    • Veldwijk MR, et al. 2002. Development and optimization of a real-time quantitative PCR-based method for the titration of AAV-2 vector stocks. Mol. Ther. 6:272-278.
    • (2002) Mol. Ther , vol.6 , pp. 272-278
    • Veldwijk, M.R.1
  • 57
    • 0031015285 scopus 로고    scopus 로고
    • Subcellular compartmentalization of adeno-associated virus type 2 assembly
    • Wistuba A, Kern A, Weger S, Grimm D, Kleinschmidt JA. 1997. Subcellular compartmentalization of adeno-associated virus type 2 assembly. J. Virol. 71:1341-1352.
    • (1997) J. Virol , vol.71 , pp. 1341-1352
    • Wistuba, A.1    Kern, A.2    Weger, S.3    Grimm, D.4    Kleinschmidt, J.A.5
  • 58
    • 0029122518 scopus 로고
    • Intermediates of adeno-associated virus type 2 assembly: identification of soluble complexes containing Rep and Cap proteins
    • Wistuba A, Weger S, Kern A, Kleinschmidt JA. 1995. Intermediates of adeno-associated virus type 2 assembly: identification of soluble complexes containing Rep and Cap proteins. J. Virol. 69:5311-5319.
    • (1995) J. Virol , vol.69 , pp. 5311-5319
    • Wistuba, A.1    Weger, S.2    Kern, A.3    Kleinschmidt, J.A.4
  • 59
    • 0033851104 scopus 로고    scopus 로고
    • Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism
    • Wu P, et al. 2000. Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism. J. Virol. 74:8635-8647.
    • (2000) J. Virol , vol.74 , pp. 8635-8647
    • Wu, P.1
  • 60
    • 0036828086 scopus 로고    scopus 로고
    • Adenovirus-facilitated nuclear translocation of adeno-associated virus type 2
    • Xiao W, Warrington KH, Jr, Hearing P, Hughes J, Muzyczka N. 2002. Adenovirus-facilitated nuclear translocation of adeno-associated virus type 2. J. Virol. 76:11505-11517.
    • (2002) J. Virol , vol.76 , pp. 11505-11517
    • Xiao, W.1    Warrington Jr, K.H.2    Hearing, P.3    Hughes, J.4    Muzyczka, N.5
  • 61
    • 2642642141 scopus 로고    scopus 로고
    • Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
    • Xiao X, Li J, Samulski RJ. 1998. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. J. Virol. 72:2224-2232.
    • (1998) J. Virol , vol.72 , pp. 2224-2232
    • Xiao, X.1    Li, J.2    Samulski, R.J.3
  • 62
    • 0035431876 scopus 로고    scopus 로고
    • A viral phospholipase A2 is required for parvovirus infectivity
    • Zadori Z, et al. 2001. A viral phospholipase A2 is required for parvovirus infectivity. Dev. Cell 1:291-302.
    • (2001) Dev. Cell , vol.1 , pp. 291-302
    • Zadori, Z.1
  • 63
    • 19944405059 scopus 로고    scopus 로고
    • Impaired nuclear transport and uncoating limit recombinant adeno-associated virus 2 vector-mediated transduction of primary murine hematopoietic cells
    • Zhong L, et al. 2004. Impaired nuclear transport and uncoating limit recombinant adeno-associated virus 2 vector-mediated transduction of primary murine hematopoietic cells. Hum. Gene Ther. 15:1207-1218.
    • (2004) Hum. Gene Ther , vol.15 , pp. 1207-1218
    • Zhong, L.1
  • 64
    • 34250727017 scopus 로고    scopus 로고
    • A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis
    • Zhong L, et al. 2007. A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis. Mol. Ther. 15:1323-1330.
    • (2007) Mol. Ther , vol.15 , pp. 1323-1330
    • Zhong, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.