Cell polarity, epithelial-mesenchymal transition, and cell-fate decision gene expression in ductal carcinoma in situ

International Journal of Surgical Oncology

Volumn 2012, Issue , 2012, Pages

  Coradini, Danila ^a,b   Boracchi, Patrizia ^a   Ambrogi, Federico ^a   Biganzoli, Elia ^a   Oriana, Saro ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b Senology Center   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84866150226     PISSN: 20901402     EISSN: 20901410     Source Type: Journal    
DOI: 10.1155/2012/984346     Document Type: Article

References (58)

1. Virnig B. A., Tuttle T. M., Shamliyan T., Kane R. L., Ductal carcinoma in Situ of the breast: a systematic review of incidence, treatment, and outcomes. Journal of the National Cancer Institute 2010 102 3 170 178 2-s2.0-76349106646 10.1093/jnci/djp482
2. Allegra C. J., Aberle D. R., Ganschow P., Hahn S. M., Lee C. N., Millon-Underwood S., Pike M. C., Reed S. D., Saftlas A. F., Scarvalone S. A., Schwartz A. M., Slomski C., Yothers G., Zon R., NIH state-of-the-science conference statement: diagnosis and management of ductal carcinoma in situ (DCIS). NIH Consensus and State-of-the-Science Statements 2009 26 2 1 27 2-s2.0-77951643029
3. Castro N. P., Osório C. A. B. T., Torres C., Bastos E. P., Mourão-Neto M., Soares F. A., Brentani H. P., Carraro D. M., Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma. Breast Cancer Research 2008 10 5, article no. R87 2-s2.0-59449085594 10.1186/bcr2157
4. Espina V., Mariani B. D., Gallagher R. I., Tran K., Banks S., Wiedemann J., Huryk H., Mueller C., Adamo L., Deng J., Petricoin E. F., Pastore L., Zaman S., Menezes G., Mize J., Johal J., Edmiston K., Liotta L. A., Malignant precursor cells pre-exist in human breast DCIS and require autophagy for survival. PLoS One 2010 5 4 2-s2.0-77956312911 10.1371/journal.pone.0010240 e10240
5. Sgroi D. C., Preinvasive breast cancer. Annual Review of Pathology 2010 5 193 221 2-s2.0-77949880150 10.1146/annurev.pathol.4.110807.092306
6. Kuerer H. M., Albarracin C. T., Yang W. T., Cardiff R. D., Brewster A. M., Symmans W. F., Hylton N. M., Middleton L. P., Krishnamurthy S., Perkins G. H., Babiera G., Edgerton M. E., Czerniecki B. J., Arun B. K., Hortobagyi G. N., Ductal carcinoma in situ: state of the science and roadmap to advance the field. Journal of Clinical Oncology 2009 27 2 279 288 2-s2.0-58249090928 10.1200/JCO.2008.18.3103
7. Collins L. C., Tamimi R. M., Baer H. J., Connolly J. L., Colditz G. A., Schnitt S. J., Outcome of patients with ductal carcinoma in situ untreated after diagnostic biopsy: results from the nurses' health study. Cancer 2005 103 9 1778 1784 2-s2.0-17644378372 10.1002/cncr.20979 (Pubitemid 40563248)
8. Vincent-Salomon A., Lucchesi C., Gruel N., Raynal V., Pierron G., Goudefroye R., Reyal F., Radvanyi F., Salmon R., Thiery J. P., Sastre-Garau X., Sigal-Zafrani B., Fourquet A., Delattre O., Integrated genomic and transcriptomic analysis of ductal carcinoma in situ of the breast. Clinical Cancer Research 2008 14 7 1956 1965 2-s2.0-42249095217 10.1158/1078-0432.CCR-07- 1465 (Pubitemid 351551104)
9. Tamimi R. M., Baer H. J., Marotti J., Galan M., Galaburda L., Fu Y., Deitz A. C., Connolly J. L., Schnitt S. J., Colditz G. A., Collins L. C., Comparison of molecular phenotypes of ductal carcinoma in situ and invasive breast cancer. Breast Cancer Research 2008 10 4, article no. R67 2-s2.0-57749118336 10.1186/bcr2128
10. Allred D. C., Wu Y., Mao S., Nagtegaal I. D., Lee S., Perou C. M., Mohsin S. K., O'Connell P., Tsimelzon A., Medina D., Ductal carcinoma in situ and the emergence of diversity during breast cancer evolution. Clinical Cancer Research 2008 14 2 370 378 2-s2.0-38949105905 10.1158/1078-0432.CCR-07-1127 (Pubitemid 351226103)
11. Emery L. A., Tripathi A., King C., Kavanah M., Mendez J., Stone M. D., De Las Morenas A., Sebastiani P., Rosenberg C. L., Early dysregulation of cell adhesion and extracellular matrix pathways in breast cancer progression. American Journal of Pathology 2009 175 3 1292 1302 2-s2.0-70349243186 10.2353/ajpath.2009.090115
12. Gauthier M. L., Berman H. K., Miller C., Kozakeiwicz K., Chew K., Moore D., Rabban J., Chen Y. Y., Kerlikowske K., Tlsty T. D., Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors. Cancer Cell 2007 12 5 479 491 2-s2.0-35748943534 10.1016/j.ccr.2007.10.017 (Pubitemid 350046408)
13. Tomaskovic-Crook E., Thompson E. W., Thiery J. P., Epithelial to mesenchymal transition and breast cancer. Breast Cancer Research 2009 11 6, article no. 213 2-s2.0-77949794643 10.1186/bcr2416
14. Derynck R., Akhurst R. J., Balmain A., TGF- β signaling in tumor suppression and cancer progression. Nature Genetics 2001 29 2 117 129 2-s2.0-0034785348 10.1038/ng1001-117 (Pubitemid 32952643)
15. Xu J., Lamouille S., Derynck R., TGF- β -induced epithelial to mesenchymal transition. Cell Research 2009 19 2 156 172 2-s2.0-59449090107 10.1038/cr.2009.5
16. Heldin C. H., Landström M., Moustakas A., Mechanism of TGF- β signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition. Current Opinion in Cell Biology 2009 21 2 166 176 2-s2.0-63749105896 10.1016/j.ceb.2009.01.021
17. Mani S. A., Guo W., Liao M. J., Eaton E. N., Ayyanan A., Zhou A. Y., Brooks M., Reinhard F., Zhang C. C., Shipitsin M., Campbell L. L., Polyak K., Brisken C., Yang J., Weinberg R. A., The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008 133 4 704 715 2-s2.0-43049165453 10.1016/j.cell.2008.03.027 (Pubitemid 351636299)
18. Morel A. P., Lièvre M., Thomas C., Hinkal G., Ansieau S., Puisieux A., Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS One 2008 3 8 2-s2.0-51449085561 10.1371/journal.pone.0002888 e2888
19. Creighton C. J., Chang J. C., Rosen J. M., Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. Journal of Mammary Gland Biology and Neoplasia 2010 15 2 253 260 2-s2.0-77954861745 10.1007/s10911-010-9173-1
20. Moreno-Bueno G., Portillo F., Cano A., Transcriptional regulation of cell polarity in EMT and cancer. Oncogene 2008 27 55 6958 6969 2-s2.0-56749095797 10.1038/onc.2008.346
21. Simpson P. T., Reis-Filho J. S., Gale T., Lakhani S. R., Molecular evolution of breat cancer. Journal of Pathology 2005 205 2 248 254 2-s2.0-13644259990 10.1002/path.1691 (Pubitemid 40227995)
22. Micalizzi D. S., Ford H. L., Epithelial-mesenchymal transition in development and cancer. Future Oncology 2009 5 8 1129 1143 2-s2.0-75649086115 10.2217/fon.09.94
23. Blick T., Widodo E., Hugo H., Waltham M., Lenburg M. E., Neve R. M., Thompson E. W., Epithelial mesenchymal transition traits in human breast cancer cell lines. Clinical and Experimental Metastasis 2008 25 6 629 642 2-s2.0-47549102418 10.1007/s10585-008-9170-6
24. Wodarz A., Näthke I., Cell polarity in development and cancer. Nature Cell Biology 2007 9 9 1016 1024 2-s2.0-34548295877 10.1038/ncb433 (Pubitemid 47342312)
25. Müller H. A. J., Genetic control of epithelial cell polarity: lessons from Drosophila. Developmental Dynamics 2000 218 1 52 67 2-s2.0-0342859304 10.1002/(SICI)1097-0177(200005)218:152::AID-DVDY5>3.0.CO;2- L
26. Martin-Belmonte F., Mostov K., Regulation of cell polarity during epithelial morphogenesis. Current Opinion in Cell Biology 2008 20 2 227 234 2-s2.0-41549086164 10.1016/j.ceb.2008.01.001
27. Liu M., Casimiro M. C., Wang C., Shirley L. A., Jiao X., Katiyar S., Ju X., Li Z., Yu Z., Zhou J., Johnson M., Fortina P., Hyslop T., Windle J. J., Pestell R. G., p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo. Proceedings of the National Academy of Sciences of the United States of America 2009 106 45 19035 19039 2-s2.0-73149086829 10.1073/pnas.0910009106
28. Lugli A., Iezzi G., Hostettler I., Muraro M. G., Mele V., Tornillo L., Carafa V., Spagnoli G., Terracciano L., Zlobec I., Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer. British Journal of Cancer 2010 103 3 382 390 2-s2.0-77955051047 10.1038/sj.bjc.6605762
29. Lawson J. C., Blatch G. L., Edkins A. L., Cancer stem cells in breast cancer and metastasis. Breast Cancer Research and Treatment 2009 118 2 241 254 2-s2.0-70350228497 10.1007/s10549-009-0524-9
30. Manavathi B., Singh K., Kumar R., MTA family of coregulators in nuclear receptor biology and pathology. Nuclear Receptor Signaling 2007 5, article e010 2-s2.0-38749123529
31. Fujita N., Kajita M., Taysavang P., Wade P. A., Hormonal regulation of metastasis-associated protein 3 transcription in breast cancer cells. Molecular Endocrinology 2004 18 12 2937 2949 2-s2.0-9644270295 10.1210/me.2004-0258 (Pubitemid 39577917)
32. Xu J., Wu R. C., O'Malley B. W., Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family. Nature Reviews Cancer 2009 9 9 615 630 2-s2.0-69249110003 10.1038/nrc2695
33. Greijer A. E., van der Groep P., Kemming D., Shvarts A., Semenza G. L., Meijer G. A., van de Wiel M. A., Belien J. A. M., van Diest P. J., van der Wall E., Up-regualtion of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor I (HIF-I). Journal of Pathology 2005 206 3 291 304 2-s2.0-21344438419 10.1002/path.1778 (Pubitemid 40903193)
34. Schoppmann S. F., Tamandl D., Roberts L., Jomrich G., Schoppmann A., Zwrtek R., Dubsky P., Gnant M., Jakesz R., Birner P., HER2/neu expression correlates with vascular endothelial growth factor-C and lymphangiogenesis in lymph node-positive breast cancer. Annals of Oncology 2009 21 5 955 960 2-s2.0-77953342817 10.1093/annonc/mdp532
35. Kouros-Mehr H., Kim J. W., Bechis S. K., Werb Z., GATA-3 and the regulation of the mammary luminal cell fate. Current Opinion in Cell Biology 2008 20 2 164 170 2-s2.0-41549107036 10.1016/j.ceb.2008.02.003
36. Asselin-Labat M. L., Sutherland K. D., Barker H., Thomas R., Shackleton M., Forrest N. C., Hartley L., Robb L., Grosveld F. G., van der Wees J., Lindeman G. J., Visvader J. E., Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nature Cell Biology 2007 9 2 201 209 2-s2.0-33847126689 10.1038/ncb1530 (Pubitemid 46420863)
37. Abd El-Rehim D. M., Pinder S. E., Paish C. E., Bell J., Balmey R. W., Robertson J. F. R., Nicholson R. I., Ellis I. O., Expression of luminal and basal cytokeratins in human breast carcinoma. Journal of Pathology 2004 203 2 661 671 2-s2.0-2642563617 10.1002/path.1559 (Pubitemid 38714103)
38. Hoadley K. A., Weigman V. J., Fan C., Sawyer L. R., He X., Troester M. A., Sartor C. I., Rieger-House T., Bernard P. S., Carey L. A., Perou C. M., EGFR associated expression profiles vary with breast tumor subtype. BMC Genomics 2007 8, article no. 258 2-s2.0-35248889408 10.1186/1471-2164-8-258 (Pubitemid 47559211)
39. Ferrari F., Bortoluzzi S., Coppe A., Sirota A., Safran M., Shmoish M., Ferrari S., Lancet D., Danieli G. A., Bicciato S., Novel definition files for human GeneChips based on GeneAnnot. BMC Bioinformatics 2007 8, article no. 446 2-s2.0-38649085333 10.1186/1471-2105-8-446 (Pubitemid 351168204)
40. Benjamini Y., Hochberg Y., Controlling the false discovery rate. A practical and powerful approach to multiple testing. Journal of Royal Statistical Society B 1995 57 284 300
41. Husson F., Lê S., Pagès J., Exploratory Multivariate Analysis by Example Using R 2010 Boca Raton, Fla, USA CRC Press Computer Science and Data Analysis Series
42. Jobson J. D., Applied Multivariate Data Analysis. Volume 2. Categorical and Multivariate Methods 1992 Berlin, Germany Springer
43. Sleeman K. E., Kendrick H., Ashworth A., Isacke C. M., Smalley M. J., CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. Breast Cancer Research 2005 8 1, article no. R7 2-s2.0-33750470097 10.1186/bcr1371
44. Ponti D., Costa A., Zaffaroni N., Pratesi G., Petrangolini G., Coradini D., Pilotti S., Pierotti M. A., Daidone M. G., Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Research 2005 65 13 5506 5511 2-s2.0-21344454219 10.1158/0008-5472.CAN-05-0626 (Pubitemid 40911148)
45. Dontu G., El-Ashry D., Wicha M. S., Breast cancer, stem/progenitor cells and the estrogen receptor. Trends in Endocrinology and Metabolism 2004 15 5 193 197 2-s2.0-3042525924 10.1016/j.tem.2004.05.011 (Pubitemid 38833988)
46. Casarsa C., Bassani N., Ambrogi F., Zabucchi G., Boracchi P., Biganzoli E., Coradini D., danila.coradini@yahoo.it Epithelial-to-mesenchymal transition, cell polarity and stemness-associated features in malignant pleural mesothelioma. Cancer Letters 2011 302 2 136 143 10.1016/j.canlet.2011.01.009
47. Petersen O. W., Polyak K., Stem cells in the human breast. Cold Spring Harbor perspectives in biology 2010 2 5 a003160 2-s2.0-77955287645 10.1101/cshperspect.a003160
48. Tiede B., Kang Y., ykang@princeton.edu From milk to malignancy: the role of mammary stem cells in development, pregnancy and breast cancer. Cell Research 2011 21 2 245 257 10.1038/cr.2011.11
49. Bracken A. P., Dietrich N., Pasini D., Hansen K. H., Helin K., Genome-wide mapping of polycomb target genes unravels their roles in cell fate transitions. Genes and Development 2006 20 9 1123 1136 2-s2.0-33646870495 10.1101/gad.381706
50. Pietersen A. M., Evers B., Prasad A. A., Tanger E., Cornelissen-Steijger P., Jonkers J., van Lohuizen M., Bmi1 regulates stem cells and proliferation and differentiation of committed cells in mammary epithelium. Current Biology 2008 18 14 1094 1099 2-s2.0-47049090497 10.1016/j.cub.2008.06.070
51. Tickenbrock L., Hehn S., Sargin B., Choudhary C., Bäumer N., Buerger H., Schulte B., Müller O., Berdel W. E., Müller-Tidow C., Serve H., Activation of Wnt signalling in acute myeloid leukemia by induction of Frizzled-4. International Journal of Oncology 2008 33 6 1215 1221 2-s2.0-59049084124 10.3892/ijo00000111
52. Band A. M., Laiho M., mlaiho1@jhmi.edu Crosstalk of TGF- β and estrogen receptor signaling in breast cancer. Journal of Mammary Gland Biology and Neoplasia 2011 16 2 109 115 10.1007/s10911-011-9203-7
53. Dontu G., Jackson K. W., McNicholas E., Kawamura M. J., Abdallah W. M., Wicha M. S., Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells. Breast Cancer Research 2004 6 6 R605 615 2-s2.0-18944375734
54. Suzuki T., Miki Y., Ohuchi N., Sasano H., Intratumoral estrogen production in breast carcinoma: significance of aromatase. Breast Cancer 2008 15 4 270 277 2-s2.0-59149105699
55. Hudelist G., Wülfing P., Kersting C., Burger H., Mattsson B., Czerwenka K., Kubista E., Gschwantler-Kaulich D., Fink-Retter A., Singer C. F., Expression of aromatase and estrogen sulfotransferase in preinvasive and invasive breast cancer. Journal of Cancer Research and Clinical Oncology 2008 134 1 67 73 2-s2.0-35848943029 10.1007/s00432-007-0249-2 (Pubitemid 350060686)
56. Díaz-Cruz E. S., esd24@georgetown.edu Sugimoto Y., Gallicano G. I., Brueggemeier R. W., Furth P. A., Comparison of increased aromatase versus ER α in the generation of mammary hyperplasia and cancer. Cancer Research 2011 71 16 5477 5487 10.1158/0008-5472.CAN-10-4652
57. Shibuya R., Suzuki T., Miki Y., Yoshida K., Moriya T., Ono K., Akahira J. I., Ishida T., Hirakawa H., Evans D. B., Sasano H., Intratumoral concentration of sex steroids and expression of sex steroid-producing enzymes in ductal carcinoma in situ of human breast. Endocrine-Related Cancer 2008 15 1 113 124 2-s2.0-41349105278 10.1677/ERC-07-0092 (Pubitemid 351449732)
58. Lonning P. E., per.lonning@helse-bergen.no The potency and clinical efficacy of aromatase inhibitors across the breast cancer continuum. Annals of Oncology 2011 22 3 503 514 10.1093/annonc/mdq337