Expression of the aldo-ketoreductases AKR1B1 and AKR1B10 in human cancers

Frontiers in Pharmacology

Volumn 3 JUN, Issue , 2012, Pages

  Laffin, Brian ^a   Petrash, J Mark ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

AKR1B1; AKR1B10; Aldose reductase; Cancer; HSIR; Leukemia; Meta analysis

Indexed keywords

ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; OXIDOREDUCTASE;

ACUTE GRANULOCYTIC LEUKEMIA; AKR1B1 GENE; AKR1B10 GENE; ARTICLE; B CELL LEUKEMIA; CANCER PROGNOSIS; CANCER SURVIVAL; CANCER TISSUE; DISEASE COURSE; GENE; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC DATABASE; HUMAN; LIVER CANCER; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG SQUAMOUS CELL CARCINOMA; MULTIPLE MYELOMA; NEOPLASM; PANCREAS CANCER; PROSTATE CANCER; T CELL LEUKEMIA;

EID: 84866148364     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2012.00104     Document Type: Article

References (31)

1. Aiello, L. P., Avery, R. L., Arrigg, P. G., Keyt, B. A., Jampel, H. D., Shah, S. T., Pasquale, L. R., Thieme, H., Iwamoto, M. A., Park, J. E., Nguyen, H. V., Aiello, L. M., Fer-rara, N., and King, G. L. (1994). Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N. Engl. J. Med. 331, 1480-1487.
2. Cha, D. R., Kim, N. H., Yoon, J. W., Jo, S. K., Cho, W. Y., Kim, H. K., and Won, N. H. (2000). Role of vascular endothelial growth factor in diabetic nephropathy. Kidney Int. Suppl. 77, S104-S112.
3. Dan, S., Shirakawa, M., Mukai, Y., Yoshida,Y.,Yamazaki,K.,Kawaguchi, T., Matsuura, M., Nakamura, Y., and Yamori, T. (2003). Identification of candidate predictive markers of anti-cancer drug sensitivity using a panel of human cancer cell lines. Cancer Sci. 94, 1074-1082.
4. Fukumoto, S.,Yamauchi,N., Moriguchi, H., Hippo, Y., Watanabe, A., Shibahara, J., Taniguchi, H., Ishikawa, S., Ito, H., Yamamoto, S., Iwanari, H., Hironaka, M., Ishikawa, Y., Niki, T., Sohara, Y., Kodama, T., Nishimura, M., Fukayama, M., Dosaka-Akita, H., and Aburatani, H. (2005). Overexpression of the aldo-ketoreductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas. Clin. Cancer Res. 11, 1776-1785.
5. Haferlach, T., Kohlmann, A., Wieczorek, L., Basso, G., Kronnie, G. T., Béné, M. C., De Vos, J., Hernández, J. M., Hofmann, W. K., Mills, K. I., Gilkes, A., Chiaretti, S., Shurtleff, S. A., Kipps,T. J., Rassenti, L. Z., Yeoh, A. E., Papenhausen, P. R., Liu, W. M., Williams, P. M., and Foà, R. (2010). Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microar-ray Innovations in Leukemia Study Group. J. Clin. Oncol. 28, 2529-2537.
6. Heringlake, S., Hofdmann, M., Fiebeler, A., Manns, M. P., Schmiegel, W., and Tannapfel, A. (2010). Identification and expression analysis of the aldo-ketoreductase1-B10 gene in primary malignant liver tumours. J. Hepatol. 52, 220-227.
7. Kang, M. W., Lee, E. S., Yoon, S. Y., Jo, J., Lee, J., Kim, H. K., Choi, Y. S., Kim, K., Shim, Y. M., Kim, J., and Kim, H. (2011). AKR1B10 is associated with smoking and smoking-related non-small-cell lung cancer. J. Int. Med. Res. 39, 78-85.
8. Makiishi, T., Araki, S., Koya, D., Maeda, S., Kashiwagi, A., and Haneda, M. (2003). C-106T polymorphism of AKR1B1 is associated with diabetic nephropathy and erythrocyte aldose reductase content in Japanese subjects with type 2 diabetes mellitus. Am. J. Kidney Dis. 42, 943-951.
9. Matsunaga, T., Yamane, Y., Iida, K., Endo, S., Banno, Y., El-Kabbani, O., and Hara, A. (2011). Involvement of the aldo-ketoreductase, AKR1B10, in mitomycin-c resistance through reactive oxygen species-dependent mechanisms. Anticancer Drugs 22, 402-408.
10. Ozaki, H., Seo, M. S., Ozaki, K., Yamada, H., Yamada, E., Okamoto, N., Hof-mann, F., Wood, J. M., and Cam-pochiaro, P. A. (2000). Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neo-vascularization. Am. J. Pathol. 156, 697-707.
11. Plebuch, M., Soldan, M., Hungerer, C., Koch, L., and Maser, E. (2007). Increased resistance of tumor cells to daunorubicin after transfection of cDNAs coding for anthracycline inactivating enzymes. Cancer Lett. 255, 49-56.
12. Ramana, K. V., Tammali, R., and Srivastava, S. K. (2010). Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells. Mol. Cancer Ther. 9, 813-824.
13. Reddy, A. B., Tammali, R., Mishra, R., Srivastava, S., Srivastava, S. K., and Ramana, K. V. (2011). Aldose reductase deficiency protects sugar-induced lens opacification in rats. Chem. Biol. Interact. 191, 346-350.
14. Reddy, G. B., Satyanarayana, A., Bal-akrishna, N., Ayyagari, R., Padma, M., Viswanath, K., and Petrash, J. M. (2008). Erythrocyte aldose reductase activity and sorbitol levels in diabetic retinopathy. Mol. Vis. 14, 593-601.
15. Saraswat, M., Mrudula, T., Kumar,P. U., Suneetha, A., RaoRao, T. S., Srini-vasulu, M., and Reddy, B. (2006). Overexpression of aldose reductase in human cancer tissues. Med. Sci. Monit. 12, CR525-CR529.
16. Saraswat, M., Muthenna, P., Surya-narayana, P., Petrash, J. M., and Reddy, G. B. (2008). Dietary sources of aldose reductase inhibitors: prospects for alleviating diabetic complications. Asia Pac. J. Clin. Nutr. 17, 558-565.
17. Schmitz, K. J., Sotiropoulos, G. C., Baba, H. A., Schmid, K. W., Müller, D., Paul, A., Auer, T., Gamerith, G., and Loeffler-Ragg, J. (2011). AKR1B10 expression is associated with less aggressive hepatocellular carcinoma: a clinicopathological study of 168 cases. Liver Int. 31, 810-816.
18. Suryanarayana, P., Kumar, P. A., Saraswat, M., Petrash, J. M., and Reddy, G. B. (2004). Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract. Mol. Vis. 10, 148-154.
19. Suryanarayana, P., Saraswat, M., Petrash, J. M., and Reddy, G. B. (2007). Emblica officinalis and its enriched tannoids delay streptozotocin-induced diabetic cataract in rats. Mol. Vis. 13, 1291-1297.
20. Tammali, R., Reddy, A. B., Ramana, K. V., Petrash, J. M., and Srivas-tava, S. K. (2009). Aldose reduc-tase deficiency in mice prevents azoxymethane-induced colonic pre-neoplastic aberrant crypt foci formation. Carcinogenesis 30, 799-807.
21. Tammali, R., Reddy, A. B., Saxena, A., Rychahou, P. G., Evers, B. M., Qiu, S., Awasthi, S., Ramana, K. V., and Srivastava, S. K. (2011a). Inhibition of aldose reductase prevents colon cancer metastasis. Carcinogenesis 32, 1259-1267.
22. Tammali, R., Saxena, A., Srivastava, S. K., and Ramana, K. V. (2011b). Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells. J. Biol. Chem. 286, 24089-24100.
23. Tammali, R., Reddy, A. B., Srivastava, S. K., and Ramana, K.V. (2011c). Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo. Angiogenesis 14, 209-221.
24. Woenckhaus, M., Klein-Hitpass, L., Grepmeier, U., Merk, J., Pfeifer, M., Wild, P., Bettstetter, M., Wuensch, P., Blaszyk, H., Hartmann, A., Hofs-taedter, F., and Dietmaier, W. (2006). Smoking and cancer-related gene expression in bronchial epithelium and non-small-cell lung cancers. J. Pathol. 210, 192-204.
25. Wolford, J. K., Yeatts, K. A., Red Eagle, A. R., Nelson, R. G., Knowler, W. C., and Hanson, R. L. (2006). Variants in the gene encoding aldose reductase (AKR1B1) and diabetic nephropa-thy in American Indians. Diabet. Med. 23, 367-376.
26. Yadav, U. C., Ramana, K. V., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., and Srivastava, S. K. (2009). Inhibition of aldose reductase prevents experimental allergic airway inflammation in mice. PLoS ONE 4, e6535. doi:10.1371/journal.pone.0006535
27. Yadav, U. C., Shoeb, M., Srivastava, S. K., and Ramana, K. V. (2011). Aldose reductase deficiency protects from autoimmune- and endotoxin-induced uveitis in mice. Invest. Oph-thalmol. Vis. Sci. 52, 8076-8085.
28. Yadav, U. C., Srivastava, S. K., and Ramana, K. V. (2007). Aldose reduc-tase inhibition prevents endotoxin-induced uveitis in rats. Invest. Oph-thalmol. Vis. Sci. 48, 4634-4642.
29. Yang, B., Hodgkinson, A., Oates, P. J., Millward, B. A., and Demaine, A. G. (2008). High glucose induction of DNA-binding activity of the transcription factor NFkappaB in patients with diabetic nephropa-thy. Biochim. Biophys. Acta 1782, 295-302.
30. Zablocki, G. J., Ruzycki, P. A., Over-turf, M. A., Palla, S., Reddy, G. B., and Petrash, J. M. (2011). Aldose reductase-mediated induction of epithelium-to-mesenchymal transition (EMT) in lens. Chem. Biol. Interact. 191, 351-356.
31. Zhong, L., Shen, H., Huang, C., Jing, H., and Cao, D. (2011). AKR1B10 induces cell resistance to daunoru-bicin and idarubicin by reducing C13 ketonic group. Toxicol. Appl. Pharmacol. 255, 40-47.