Aldose reductase-mediated induction of epithelium-to-mesenchymal transition (EMT) in lens

Chemico-Biological Interactions

Volumn 191, Issue 1-3, 2011, Pages 351-356

  Zablocki, Gregory J ^a   Ruzycki, Philip A ^a   Overturf, Michelle A ^a   Palla, Suryanarayana ^b   Reddy, G Bhanuprakesh ^b   Petrash, J Mark ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF NUTRITION   (India)

Author keywords

Aldo keto reductase; Cataract; Diabetes; EMT; Epithelial to mesenchymal transition

Indexed keywords

ALDEHYDE REDUCTASE; ALPHA SMOOTH MUSCLE ACTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; CATARACT; CELL COUNT; CELL DENSITY; CELL NUCLEUS; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; LENS EPITHELIUM; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ALDEHYDE REDUCTASE; ANIMALS; BIOLOGICAL MARKERS; CAPSULE OPACIFICATION; CELL PROLIFERATION; DIABETES COMPLICATIONS; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LENS, CRYSTALLINE; MICE; MICE, TRANSGENIC; PHENOTYPE;

MUS; MUS MUSCULUS;

EID: 79957576582     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2011.02.005     Document Type: Conference Paper

References (31)

1. S. Bassnett, Three-dimensional reconstruction of cells in the living lens: the relationship between cell length and volume, Exp. Eye Res. 81 (2005) 716-723.
2. S.P. Bhat, The ocular lens epithelium, Biosci. Rep. 21 (2001) 537-563.
3. D. Chandra, K.V. Ramana, B. Friedrich, S. Srivastava, A. Bhatnagar, S.K. Srivastava, Role of aldose reductase in TNF-alpha-induced apoptosis of vascular endothelial cells, Chem. Biol. Interact. 143-144 (2003) 605-612. (Pubitemid 36253606)
4. G.J. Harocopos, K.M. Alvares, A.E. Kolker, D.C. Beebe, Human age-related cataract and lens epithelial cell death, Invest. Ophthalmol. Vis. Sci. 39 (1998) 2696-2706. (Pubitemid 28558229)
5. R.E. Hay, U.P. Andley, J.M. Petrash, Expression of recombinant bovine gamma B- gamma C- and gamma D-crystallins and correlation with native proteins, Exp. Eye Res. 58 (1994) 573-584.
6. S.P. Huang, S. Palla, P. Ruzycki, A. Varma, T. Harter, G.B. Reddy, J.M. Petrash, Aldo-keto reductases in the eye, J. Ophthalmol. (2010).
7. J.H. Kinoshita, C. Nishimura, The involvement of aldose reductase in diabetic complications, Diab.-Metab. Rev. 4 (1988) 323-337.
8. B.E. Klein, R. Klein, Q. Wang, S.E. Moss, Older-onset diabetes and lens opacities. The Beaver Dam Eye Study, Ophthal. Epidemiol. 2 (1995) 49-55.
9. Y. Kumamoto, Y. Takamura, E. Kubo, S. Tsuzuki, Y. Akagi, Epithelial cell density in cataractous lenses of patients with diabetes: association with erythrocyte aldose reductase, Exp. Eye Res. 85 (2007) 393-399.
10. A.Y. Lee, S.S. Chung, Contributions of polyol pathway to oxidative stress in diabetic cataract, FASEB J. 13 (1999) 23-30. (Pubitemid 29038271)
11. M. Lorenzi, The polyol pathway as amechanismfor diabetic retinopathy: attractive, elusive, and resilient, Exp. Diab. Res. 2007 (2007) 61038-61047.
12. I.G. Obrosova, S.S. Chung, P.F. Kador, Diabetic cataracts: mechanisms and management, Diab./Metab. Res. Rev. 26 (2010) 172-180.
13. J.M. Petrash, T.M. Harter, C.S. Devine, P.O. Olins, A. Bhatnagar, S.Q. Liu, S.K. Srivastava, Involvement of cysteine residues in catalysis and inhibition of human aldose reductase - site-directed mutagenesis of cys-80, cys-298, and cys-303, J. Biol. Chem. 267 (1992) 24833-24840.
14. APladzyk, A.B. Reddy, U.C. Yadav, R. Tammali, K.V. Ramana, S.K. Srivastava, Inhibition of aldose reductase prevents lipopolysaccharide-induced inflammatory response in human lens epithelial cells, Invest. Ophthalmol. Vis. Sci. 47 (2006) 5395-5403. (Pubitemid 46723790)
15. K.V. Ramana, D. Chandra, S. Srivastava, A. Bhatnagar, B.B. Aggarwal, S.K. Srivastava, Aldose reductase mediates mitogenic signaling in vascular smooth muscle cells, J. Biol. Chem. 277 (2002) 32063-32070.
16. K.V. Ramana, D. Chandra, S. Srivastava, A. Bhatnagar, S.K. Srivastava, Aldose reductase mediates the mitogenic signals of cytokines, Chem. Biol. Interact. 143-144 (2003) 587-596. (Pubitemid 36253605)
17. K.V. Ramana, A.A. Fadl, R. Tammali, A.B.M. Reddy, A.K. Chopra, S.K. Srivastava, Aldose reductase mediates the lipopolysaccharide-induced release of inflammatory mediators in RAW264.7 murine macrophages, J. Biol. Chem. 281 (2006) 33019-33029.
18. K.V. Ramana, B. Friedrich, R. Tammali, M.B. West, A. Bhatnagar, S.K. Srivastava, Requirement of aldose reductase for the hyperglycemic activation of protein kinase C and formation of diacylglycerol in vascular smooth muscle cells, Diabetes 54 (2005) 818-829. (Pubitemid 40322087)
19. K.V. Ramana, R. Tammali, A.B. Reddy, A. Bhatnagar, S.K. Srivastava, Aldose reductase-regulated tumor necrosis factor-alpha production is essential for high glucose-induced vascular smooth muscle cell growth, Endocrinology 148 (2007) 4371-4384. (Pubitemid 47295687)
20. G.B. Reddy, A. Satyanarayana, N. Balakrishna, R. Ayyagari, M. Padma, K. Viswanath, J.M. Petrash, Erythrocyte aldose reductase activity and sorbitol levels in diabetic retinopathy, Mol. Vis. 14 (2008) 593-601.
21. L.W. Reneker, Q. Chen, A. Bloch, L. Xie, G. Schuster, P.A. Overbeek, Chick delta1-crystallin enhancer influences mouse alphaA-crystallin promoter activity in transgenic mice, Invest. Ophthalmol. Vis. Sci. 45 (2004) 4083-4090. (Pubitemid 39411164)
22. H.G. Struck, C. Heider, C. Lautenschlager, Changes in the lens epithelium of diabetic and non-diabetic patients with various forms of opacities in senile cataract, Klin. Monatsbl. Augenheilkd. 216 (2000) 204-209. (Pubitemid 30249796)
23. R. Tammali, A.B. Reddy, K.V. Ramana, J.M. Petrash, S.K. Srivastava, Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation, Carcinogenesis 30 (2009) 799-807.
24. The Diabetes Complications Trial Research, The effect of intensive diabetes treatment on the progression of diabetic retinopathy in insulin-dependent diabetes mellitus. The diabetes control and complications trial, Arch. Ophthalmol. 113 (1995) 36-51.
25. S.D. Varma, J.H. Kinoshita, The absence of cataracts in mice with congential hyperglycemia, Exp. Eye Res. 19 (1974) 577-582.
26. A.R. Vasavada, M. Cherian, S. Yadav, U.M. Rawal, Lens epithelial cell density and histomorphological study in cataractous lenses, J. Cataract Refract. Surg. 17 (1991) 798-804.
27. I.M.Wormstone, L. Wang, C.S. Liu, Posterior capsule opacification, Exp. Eye Res. 88 (2009) 257-269.
28. U.C. Yadav, F. Ighani-Hosseinabad, F.J. van Kuijk, S.K. Srivastava, K.V. Ramana, Prevention of posterior capsular opacification through aldose reductase inhibition, Invest. Ophthalmol. Vis. Sci. 50 (2009) 752-759.
29. U.C.S. Yadav, S.K. Srivastava, K.V. Ramana, Aldose reductase inhibition prevents endotoxin-induced uveitis in rats, Invest. Ophthalmol. Vis. Sci. 48 (2007) 4634-4642. (Pubitemid 351260981)
30. N. Yamamoto, K. Majima, T. Marunouchi, A study of the proliferating activity in lens epithelium and the identification of tissue-type stem cells, Med. Mol. Morphol. 41 (2008) 83-91. (Pubitemid 351915431)
31. B. Yang, A. Millward, A. Demaine, Functional differences between the susceptibility Z-2/C-106 and protective Z+2/T-106 promoter region polymorphisms of the aldose reductase gene may account for the association with diabetic microvascular complications, Biochim. Biophys. Acta 1639 (2003) 1-7.