Prenatal tolerability of acetaminophen and other over-the-counter non-selective cyclooxygenase inhibitors

Pharmacological Reports

Volumn 64, Issue 3, 2012, Pages 521-527

  Burdan, Franciszek ^a,b   Starosławska, Elzbieta ^b   Szumiło, Justyna ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b ST JOHN S CANCER CENTER   (Poland)

Author keywords

Analgesic; Antipyretic; Drug safety; NSAID; Over the counter medication; Pregnancy

Indexed keywords

ACETYLSALICYLIC ACID; DICLOFENAC; IBUPROFEN; NAPROXEN; NON PRESCRIPTION DRUG; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PROSTAGLANDIN SYNTHASE INHIBITOR;

ASTHMA; BRAIN HEMORRHAGE; CONGENITAL MALFORMATION; CRYPTORCHISM; DEVELOPMENTAL TOXICITY; DRUG MEGADOSE; DRUG TOLERABILITY; DUCTUS ARTERIOSUS CONSTRICTION; EMBRYO DEVELOPMENT; FETUS DEVELOPMENT; FETUS DISEASE; FETUS OUTCOME; HIGH RISK PREGNANCY; HUMAN; INTRAUTERINE GROWTH RETARDATION; LUNG EMBOLISM; MATERNAL FEVER; MATERNAL PAIN; MATERNAL PHLEBOTHROMBOSIS; OLIGOHYDRAMNIOS; PERSISTENT PULMONARY HYPERTENSION; PREECLAMPSIA; PREGNANCY DISORDER; PREMATURE LABOR; PRENATAL DRUG EXPOSURE; PRENATAL TOXICITY; PROLONGED PREGNANCY; REDUCED FETAL RENAL PERFUSION; REVIEW; SPONTANEOUS ABORTION; STILLBIRTH; TOXICITY;

EID: 84866141496     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(12)70847-2     Document Type: Review

References (56)

1. Abe K, Honein MA, Moore CA: Maternal febrile illnesses, medication use, and the risk of congenital renal anomalies. Birth Defects Res A Clin Mol Teratol, 2003, 67, 911-918.
2. Briggs GG, Freeman RK, Yaffe SJ: Drugs in pregnancy and lactation. A reference guide to fetal and neonatal risk. 7th edn., Lippincott Williams & Wilkins, Philadelphia, 2005.
3. Brown AS, Begg MD, Gravenstein S, Schaefer CA, Wyatt RJ, Bresnahan M, Babulas VP, Susser ES: Serologic evidence of prenatal influenza in the etiology of schizophrenia. Arch Gen Psychiatry, 2004, 61, 774-780.
4. Burdan F: Developmental effects of propyphenazone in analgesic and antipyretic combination with caffeine or paracetamol. Hum Exp Toxicol, 2004, 23, 235-244.
5. Burdan F, Chałas A, Szumiło J: Cyclooxygenase and prostanoids - biological implications (Polish). Postepy Hig Med Dosw (online), 2006, 60, 129-141.
6. Burdan F, Pliszczynska-Steuden M, Rozylo-Kalinowska I, Chalas A, Rozylo TK, Staroslawska E, Klepacz R, Szumilo J: Developmental outcome after exposure to cyclooxygenase inhibitors during pregnancy and lactation. Reprod Toxicol, 2011, 32, 407-417.
7. Burdan F, Szumilo J, Dudka J, Korobowicz A, Klepacz R: Congenital ventricular septal defects and prenatal exposure to cyclooxygenase inhibitors. Braz J Med Biol Res, 2006, 39, 925-934.
8. Burdan F, Szumilo J, Klepacz R: Maternal toxicity of nonsteroidal anti-inflammatory drugs as an important factor affecting prenatal development. Reprod Toxicol, 2009, 28, 239-244.
9. Burdan F, Szumilo J, Korobowicz-Markiewicz A, Dyndor K, Szumilo M, Klepacz R: Unusual interleukin-1 and -6 expression in fetal cartilage is associated with placental abnormalities. Folia Histochem Cytobiol, 2010, 48, 30-36.
10. Cabbage LA, Neal JL: Over-the-counter medications and pregnancy: An integrative review. Nurse Pract, 2011, 36, 22-28.
11. Capone ML, Tacconelli S, Rodriguez LG, Patrignani P: NSAIDs and cardiovascular disease: transducing human pharmacology results into clinical read-outs in the general population. Pharmacol Rep, 2010, 62, 530-535.
12. Chun LJ, Tong MJ, Busuttil RW, Hiatt JR: Acetaminophen hepatotoxicity and acute liver failure. J Clin Gastroenterol, 2009, 43, 342-349.
13. Conte D, Romanelli F, Fillo S, Guidetti L, Isidori A, Franceschi F, Latini M, di Luigi L: Aspirin inhibits androgen response to chorionic gonadotropin in humans. Am J Physiol, 1999, 277, E1032-1037.
14. Cook JC, Jacobson CF, Gao F, Tassinari MS, Hurtt ME, DeSesso JM: Analysis of the nonsteroidal anti-inflammatory drug literature for potential developmental toxicity in rats and rabbits. Birth Defects Res B Dev Reprod Toxicol, 2003, 68, 5-26.
15. Ericson A, Källén BA: Nonsteroidal anti-inflammatory drugs in early pregnancy. Reprod Toxicol, 2001, 15, 371-375.
16. Feldkamp ML, Meyer RE, Krikov S, Botto LD: Acetaminophen use in pregnancy and risk of birth defects, findings from the National Birth Defects Prevention Study. Obstet Gynecol, 2010, 115, 109-115.
17. Food and Drug Administration, HHS: Labeling and effectiveness testing: sunscreen drug products for over-the- counter human use. Final rule. Fed Regist, 2011, 76, 35620-35665.
18. Glover DD, Amonkar M, Rybeck BF, Tracy TS: Prescription, over-the-counter, and herbal medicine use in a rural, obstetric population. Am J Obstet Gynecol, 2003, 188, 1039-1045.
19. Graham GG, Scott KF: Mechanism of action of paracetamol. Am J Ther, 2005, 12, 46-55.
20. Jensen MS, Rebordosa C, Thulstrup AM, Toft G, Sørensen HT, Bonde JP, Henriksen TB, Olsen J: Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism. Epidemiology, 2010, 21, 779-785.
21. Källén BA, Otterblad-Olausson P: Maternal drug use in early pregnancy and infant cardiovascular defect. Reprod Toxicol, 2003, 17, 255-261.
22. Kamysheva E, Wertheim EH, Skouteris H, Paxton SJ, Milgrom J: Frequency, severity, and effect on life of physical symptoms experienced during pregnancy. J Midwifery Womens Health, 2009, 54, 43-49.
23. Klein-Schwartz W, Doyon S: Intravenous acetylcysteine for the treatment of acetaminophen overdose. Expert Opin Pharmacother, 2011, 12, 119-130.
24. Kordić-Bojinović J, Oreščanin- Dušić Z, Slavić M, Radojičić R, Spasić M, Milovanović SR, Blagojević D: Effect of indometacin pretreatment on protamine sulfate-mediated relaxation of the isolated rat uterus: the role of the antioxidative defense system. Pharmacol Rep, 2011, 63, 1019-1028.
25. Koren G: Maternal-fetal toxicology. 2nd edn., Marcel Dekker, New York, 1994.
26. Kozer E, Nikfar S, Costei A, Boskovic R, Nulman I, Koren G: Aspirin consumption during the first trimester of pregnancy and congenital anomalies, a meta-analysis. Am J Obstet Gynecol, 2002, 187, 1623-1630.
27. Li Z, Ren A, Liu J, Pei L, Zhang L, Guo Z, Li Z: Maternal flu or fever, medication use, and neural tube defects, a population-based case-control study in Northern China. Birth Defects Res AClin Mol Teratol, 2007, 79, 295-300.
28. Martínez-Frías ML, Rodríguez-Pinilla E, Prieto L: Prenatal exposure to salicylates and gastroschisis, a casecontrol study. Teratology, 1997, 56, 241-243.
29. McElhatton PR, Sullivan FM, Volans GN: Paracetamol overdose in pregnancy analysis of the outcomes of 300 cases referred to the Teratology Information Service. Reprod Toxicol, 1997, 11, 85-94.
30. Nielsen GL, Sørensen HT, Larsen H, Pedersen L: Risk of adverse birth outcome and miscarriage in pregnant users of non-steroidal anti-inflammatory drugs: population based observational study and case-control study. BMJ, 2001, 322, 266-270.
31. Ofori B, Oraichi D, Blais L, Rey E, Bérard A: Risk of congenital anomalies in pregnant users of non-steroidal anti-inflammatory drugs, A nested case-control study. Birth Defects Res B Dev Reprod Toxicol, 2006, 77, 268-279.
32. Oster ME, Riehle-Colarusso T, Alverson CJ, Correa A: Associations between maternal fever and influenza and congenital heart defects. J Pediatr, 2011, 158, 990-995.
33. Østensen M, Khamashta M, Lockshin M, Parke A, Brucato A, Carp H, Doria A et al.: Anti-inflammatory and immunosuppressive drugs and reproduction. Arthritis Res Ther, 2006, 8, 209-208.
34. Østensen ME, Skomsvoll JF: Anti-inflammatory pharmacotherapy during pregnancy. Expert Opin Pharmacother, 2004, 5, 571-580.
35. Polat B, Albayrak Y, Suleyman B, Dursun H, Odabasoglu F, Yigiter M, Halici Z, Suleyman H: Antiulcerative effect of dexmedetomidine on indomethacin-induced gastric ulcer in rats. Pharmacol Rep, 2011, 63, 518-526.
36. Prescott LF: Paracetamol (acetaminophen) - a critical bibliographic review. Taylor & Francis, London, 1996.
37. Rainsford KD: Ibuprofen - a critical bibliographic review. Taylor & Francis, London, 1999.
38. Rebordosa C, Kogevinas M, Bech BH, Sørensen HT, Olsen J: Use of acetaminophen during pregnancy and risk of adverse pregnancy outcomes. Int J Epidemiol, 2009, 38, 706-714.
39. Rebordosa C, Kogevinas M, Horváth-Puhó E, Nørgård B, Morales M, Czeizel AE, Vilstrup H et al.: Acetaminophen use during pregnancy, effects on risk for congenital abnormalities. Am J Obstet Gynecol, 2008, 198, 178.e1-7.
40. Rebordosa C, Kogevinas M, Sørensen HT, Olsen J: Prenatal exposure to paracetamol and risk of wheezing and asthma in children: a birth cohort study. Int J Epidemiol, 2008, 37, 583-590.
41. Rebordosa C, Zelop CM, Kogevinas M, Sørensen HT, Olsen J: Use of acetaminophen during pregnancy and risk of preeclampsia, hypertensive and vascular disorders: a birth cohort study. J Matern Fetal Neonatal Med, 2010, 23, 371-378.
42. Scheafer C, Peters P, Miller RK. Drugs during pregnancy and lactation, therapeutic options and risk assessment. 2nd edn., Academic Press, Oxford, 2007.
43. Scialii A: Teratology. In: Pathology of environmental and occupational disease. Ed. Craighead JE, Mosby, St. Louis, 1995, 573-588.
44. Scialli AR, Ang R, Breitmeyer J, Royal MA: A review of the literature on the effects of acetaminophen on pregnancy outcome. Reprod Toxicol, 2010, 30, 495-507.
45. Shaw GM, Todoroff K, Velie EM, Lammer EJ: Maternal illness, including fever and medication use as risk factors for neural tube defects. Teratology, 1998, 57, 1-7.
46. Singh AP, Junemann A, Muthuraman A, Jaggi AS, Singh N, Grover K, Dhawan R: Animal models of acute renal failure. Pharmacol Rep, 2012, 64, 31-44.
47. Sørensen HJ,Mortensen EL, Reinisch JM,Mednick SA: Association between prenatal exposure to analgesics and risk of schizophrenia. Br J Psychiatry, 2004, 185, 366-371.
48. Stosic R, Dunagan F, Palmer H, Fowler T, Adams I: Responsible self-medication, perceived risks and benefits of over-the-counter analgesic use. Int J Pharm Pract, 2011, 19, 236-245.
49. Suleyman H, Demircan B, Karagoz Y: Anti-inflammatory and side effects of cyclooxygenase inhibitors. Pharmacol Rep, 2007, 59, 247-258.
50. Szczeklik A. Aspirin-induced asthma: a tribute to John Vane as a source of inspiration. Pharmacol Rep, 2010, 62, 526-529.
51. Torfs CP, Katz EA, Bateson TF, Lam PK, Curry CJ: Maternal medications and environmental exposure as risk for gastroschisis. Teratology, 1996, 54, 84-92.
52. U.S. Food and Drug Administration. Pregnancy and lactation labeling [Internet]. http: //www.fda.gov/Drugs/developmentApprovalProcess/ DevelopmentResources/Labeling/ucm093307.htm/ (last access October 20, 2011).
53. Vaish V, Sanyal SN: Chemopreventive effects of NSAIDs on cytokines and transcription factors during the early stages of colorectal cancer. Pharmacol Rep, 2011, 63, 1210-1221.
54. Wang PH, Yang MJ, Lee WL, Chao HT, Yang ML, Hung JH: Acetaminophen poisoning in late pregnancy. A case report. J Reprod Med, 1997, 42, 367-371.
55. Werler MM, Mitchell AA, Hernandez-Diaz S, Honein MA: Use of over-the-counter medications during pregnancy. Am J Obstet Gynecol, 2005, 193, 771-777.
56. Wilkes JM, Clark LE, Herrera JL: Acetaminophen over-dose in pregnancy. South Med J, 2005, 98, 1118-1122.