High-performance inulin and oligofructose prebiotics increase the intestinal absorption of iron in rats with iron deficiency anaemia during the growth phase

British Journal of Nutrition

Volumn 108, Issue 6, 2012, Pages 1008-1016

  Freitas, Karine De Cássia ^a,b   Amancio, Olga Maria Silvério ^b   De Morais, Mauro Batista ^b  

^a UNIVERSIDADE FEDERAL DA GRANDE DOURADOS   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Dietary fibre; Intestinal absorption; Inulin; Iron deficiency anaemia; Rats

Indexed keywords

FRUCTOSE OLIGOSACCHARIDE; INULIN; IRON; PREBIOTIC AGENT; STARCH;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY GROWTH; BODY HEIGHT; CECUM; CONTROLLED STUDY; DRUG EFFECT; FOOD INTAKE; INTESTINE ABSORPTION; IRON ABSORPTION; IRON DEFICIENCY ANEMIA; MALE; NONHUMAN; ORGAN WEIGHT; PH; RAT; WEIGHT GAIN;

ANEMIA, IRON-DEFICIENCY; ANIMALS; CECUM; COLON; FECES; GASTROINTESTINAL CONTENTS; HEMATOCRIT; HEMOGLOBINS; HYDROGEN-ION CONCENTRATION; INTESTINAL ABSORPTION; INTESTINES; INULIN; IRON, DIETARY; MALE; OLIGOSACCHARIDES; ORGAN SIZE; PREBIOTICS; RATS; RATS, WISTAR; WEIGHT GAIN;

RATTUS; RATTUS NORVEGICUS; ZEA MAYS;

EID: 84866140202     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114511006301     Document Type: Article

References (54)

1. Van Loo J, Cummings J, Delzenne N, et al. (1999) Functional food properties of non-digestible oligosaccharides: a consensus report from the ENDO project (DGXII AIRII-CT94-1095). Br J Nutr 81, 121-132.
2. Kolida S, Tuohy K & Gibson GR (2002) Prebiotic effects of inulin and oligofructose. Br J Nutr 87, Suppl. 2, S193-S197.
3. Marteau P & Boutron-Ruault MC (2002) Nutritional advantages of probiotics and prebiotics. Br J Nutr 87, Suppl. 2, S153-S157.
4. Coudray C, Tressol JC, Gueux E, et al. (2003) Effects of inulin-type fructans of different chain length and type of branching on intestinal absorption and balance of calcium and magnesium in rats. Eur J Nutr 42, 91-98.
5. Holloway L, Moynihan S, Abrams SA, et al. (2007) Effects of oligofructose-enriched inulin on intestinal absorption of calcium and magnesium and bone turnover markers in post-menopausal women. Br J Nutr 97, 365-372.
6. van den Heuvel EGHM, Muys T, Dokkum WV, et al. (1999) Oligofructose stimulates calcium absorption in adolescents. Am J Clin Nutr 69, 544-548.
7. Ohta A, Sakai K, Takasaki M, et al. (1999) Dietary heme iron does not prevent postgastrectomy anemia but fructooligo-saccharides improve bioavailability of heme iron in rats. Int J Vitam Nutr Res 69, 348-355.
8. van den Heuvel EGHM, Schaafsma G & Muys T (1998) Non-digestible oligosaccharides do not interfere with calcium and nonheme-iron absorption in young, healthy men. Am J Clin Nutr 67, 445-451.
9. Younes H, Coudray C, Bellanger J, et al. (2001) Effects of two fermentable carbohydrates (inulin and resistant starch) and their combination on calcium and magnesium balance in rats. Br J Nutr 86, 479-485.
10. Lopez HW, Coudray C, Levrat-Verny MA, et al. (2000) Fructo- oligosaccharides enhance mineral apparent absorption and counteract the deleterious effects of phytic acid on mineral homeostasis in rats. J Nutr Biochem 11, 500-508.
11. Freitas KC, Amancio OMS, Novo NF, et al. (2006) Partially hydrolyzed guar gum increases intestinal absorption of iron in growing rats with iron deficiency anaemia. Clin Nutr 25, 851-858.
12. Medeiros LCS, Morais MB, Tahan S, et al. (2007) Clinical characteristics of pediatric patients with chronic constipation according to age group. Arq Gastroenterol 44, 340-344.
13. Morais MB, Vítolo MR, Aguirre ANC, et al. (1999) Measurement of low dietary fiber intake as a risk factor for chronic constipation in children. J Pediatric Gastroenterol Nutr 29, 132-135.
14. Davidsson L, Galan P, Cherouvrier F, et al. (1997) Biovailabil-ity in infants of iron from infant cereals: effect of dephytini-zation. Am J Clin Nutr 65, 916-920.
15. Aggett PJ, Agostoni C, Axelsson I, et al. (2002) Iron metabolism and requeriments in early childhood: do we know enough?: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr 34, 337-345.
16. Lozoff B, Jimenez E, Hagen J, et al. (2000) Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy. Pediatrics 105, E51.
17. Pitarresi G, Tripodo G, Cavallaro G, et al. (2007) Inulin-iron complexes: a potential treatment of iron deficiency anemia. Eur J Pharm Biopharm 68, 267-276.
18. Yasuda K, Roneker KR, Miller DD, et al. (2006) Supplemental dietary inulin affects the biovailability of iron in corn and soybean meal to young pigs. J Nutr 136, 3033-3038.
19. Williams CL (1995) Importance of dietary fiber in childhood. J Am Diet Assoc 95, 1140-1146.
20. Trumbo P, Schlicker S, Yates AA, et al. (2002) Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. J Am Diet Assoc 102, 1621-1630.
21. Reeves PG, Nielsen FH & Fahey GC (1993) AIN-93 purified diets for laboratory rodents: final report f the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123, 1939-1951.
22. Borel MJ, Smith SH, Brigham DE, et al. (1991) The impact of varying degrees of iron nutriture on several functional consequences of iron deficiency in rats. J Nutr 121, 729-736.
23. Marks GE, Moore CE, Kanabrocki EL, et al. (1971) Determination of trace elements in human tissue. I, Cd, Fe, Zn, Mg and Ca. Appl Spectrosc 26, 523-527.
24. Jacobs LR & White FA (1983) Modulation of mucosal cell proliferation in the intestine of rats fed a wheat bran diet. Am J Clin Nutr 37, 945-953.
25. Dirks P & Freeman HJ (1987) Effects of differing purified cellulose, pectin and hemicellulose fiber diets on mucosal morphology in the rat small and large intestine. Clin Invest Med 10, 32-38.
26. Lopez HW, Levrat-Verny M, Coudray C, et al. (2001) Class 2 resistant starches lower plasma and liver lipids and improve mineral retention in rats. J Nutr 131, 1283-1289.
27. Wintrobe M, Mollin D, Herbert V, et al. (1968) Anemias nutri-cionales. Org Mund Salud Ser Inf Técn 405, 5-39.
28. Sierra Salinas C, Martínez Costa C, Dalmau Serra J, et al. (2000) Revisión del papel de la fibra em nutrición infantile (Review of the role of fiber in child nutrition). Pediátrika 20, 129-137.
29. Dagnelie PC, van Staveren V, Verschuren SA, et al. (1989) Nutritional status of infants aged 4 to 18 months on macrobiotic diets and matched omnivorous control infants: a population-based mixed-longitudinal study. I. Weaning pattern, energy and nutrient intake. Eur J Clin Nutr 43, 311-323.
30. Kanauchi O, Araki Y, Andoh A, et al. (2000) Effect of germinated barley foodstuff administration on mineral utilization in rodents. J Gastroenterol 35, 188-194.
31. Ohta A, Ohtsuki M, Baba S, et al. (1995) Effects of fructo- oligosaccharides on the absorption of iron, calcium and magnesium in iron-deficient anemic rats. J Nutr Sci Vitami-nol 41, 281-291.
32. Delzenne N, Aertssens J, Verplaetse H, et al. (1995) Effect of fermentable fructo-oligosaccharides on mineral, nitrogen and energy digestive balance in the rat. Life Sci 57, 1579-1587.
33. Ohta A, Ohtsuki M, Uehara M, et al. (1998) Dietary fructo- oligosaccharides prevent postgastrectomy anemia and osteo-penia in rats. J Nutr 128, 485-490.
34. Sakai K, Ohta A, Shiga K, et al. (2000) The cecum and dietary short-chain fructooligosaccharides are involved in preventing postgastrectomy anemia in rats. J Nutr 130, 1608-1612.
35. Weber TK, Freitas KC, Amancio OMS, et al. (2010) Effect of dietary fibre mixture on growth and intestinal iron in rats recovering from iron-deficiency anaemia. Br J Nutr 104, 1471-1476.
36. Catani M, Amancio OMS, Fagundes-Neto U, et al. (2003) Dietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemia. Braz J Med Biol Res 36, 693-697.
37. Blachier F, Vaugelade P, Robert V, et al. (2007) Comparative capacities of the pig colon and duodenum for luminal iron absorption. Can J Physiol Pharmacol 85, 185-192.
38. Johnston KL, Johnson DM, Marks J, et al. (2006) Non-haem iron transport in the rat proximal colon. Eur J Clin Invest 36, 35-40.
39. Tako E, Glahn RP, Welch RM, et al. (2007) Dietary inulin affects the expression of intestinal enterocyte iron transporters, receptors and storage protein and alters the microbiota in the pig intestine. Br J Nutr 99, 472-480.
40. Pérez-Conesa D, López G & Ros G (2007) Effects of probio-tic, prebiotic and symbiotic follow-up infant formulas on large intestine morphology and bone mineralisation in rats. J Sci Food Agric 87, 1059-1068.
41. Frankel WL, Zhang W, Singh A, et al. (1994) Mediation of the trophic effects of short-chain fatty acids on the rat jejunum and colon. Gastroenterology 106, 375-380.
42. Bouglé D, Vaghefi-Vaezzadeh N, Roland N, et al. (2002) Influence of short-chain fatty acids on iron absorption by proximal colon. Scand J Gastroenterol 37, 1008-1011.
43. Balamurugan R, Regina Mary R, Chittaranjan C, et al. (2010) Low levels of faecal lactobacilli in women with iron-deficiency anaemia in south India. Br J Nutr 104, 931-944.
44. Patterson JK, Yasuda K, Welch RM, et al. (2010) Supplemental dietary inulin of variable chain lengths alters intestinal bacterial populations in young pigs. J Nutr 140, 2158-2161.
45. Tako E, Glahn RP & Welch RM (2008) Dietary inulin affects the expression of intestinal enterocyte iron transporters, receptors and storage protein and alters the microbiota in the pig intestine. Br J Nutr 99, 472-480.
46. Morais MB, Feste A, Miller RG, et al. (1996) Effect of resistant and digestible starch on intestinal absorption of calcium, iron, and zinc in infant pigs. Pediatr Res 39, 872-876.
47. Fukunaga T, Sasaki M, Araki Y, et al. (2003) Effects of the soluble fibre pectin on intestinal cell proliferation, fecal short chain fatty acid production and microbial population. Digestion 67, 42-49.
48. Galibois I, Desrosiers T, Guévin N, et al. (1994) Effects of dietary fibre mixtures on glucose and lipid metabolism and on mineral absorption in the rat. Ann Nutr Metab 38, 203-211.
49. Wang Y, Funk MA, Garleb KA, et al. (1994) The effect of fiber source in enteral products on fecal weight, mineral balance, and growth rate in rats. JPEN J Parenter Enteral Nutr 18, 340-345.
50. Scholz-Aherns KE & Schrezenmeir J (2007) Inulin and oligo-fructose and mineral metabolism: the evidence from animal trials. J Nutr 137, 2513-2523.
51. Wolf BW, Firkins JL & Zhang X (1998) Varying dietary concentrations of fructooligosaccharides affect apparent absorption and balance of minerals in growing rats. Nutr Res 10, 1791-1806.
52. Ohta A, Ohtsuki M, Baba S, et al. (1998) Comparison of the nutritional effects of fructo-oligosaccharides of different sugar chain length in rats. Nutr Res 1, 109-120.
53. Hallberg L, Brune M, Erlandsson M, et al. (1991) Calcium: effect of different amounts on nonheme-and heme-iron absorption in humans. Am J Clin Nutr 53, 112-119.
54. Nyman M (2002) Fermentation and bulking capacity of indigestible carbohydrates: the case of inulin and oligofructose. Br J Nutr 87, Suppl. 2, S163-S168.