Selective disruption of insulin-like growth factor-1 (IGF-1) signaling via phosphoinositide-dependent kinase-1 prevents the protective effect of IGF-1 on human cancer cell death

Journal of Biological Chemistry

Volumn 285, Issue 9, 2010, Pages 6563-6572

  Alberobello, A Teresa ^a   D'Esposito, Vittoria ^a   Marasco, Daniela ^a   Doti, Nunzianna ^a   Ruvo, Menotti ^a   Bianco, Roberto ^a   Tortora, Giampaolo ^a   Esposito, Iolanda ^a   Fiory, Francesca ^a   Miele, Claudia ^a   Beguinot, Francesco ^a   Formisano, Pietro ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOCARCINOMA CELLS; ANTI-CANCER AGENTS; ANTI-CANCER THERAPIES; ANTIAPOPTOTIC; C TERMINUS; CANCER CELLS; CETUXIMAB; CONCENTRATION-DEPENDENT; FLUORESCEIN ISOTHIOCYANATE; GROWTH FACTOR; HUMAN CANCER CELLS; IN-VITRO; INSULIN-LIKE GROWTH FACTOR-1; MCF-7 BREAST CANCER CELLS; MCF-7 CELLS; PHOSPHOINOSITIDES; PROTECTIVE EFFECTS; PROTEIN KINASE C; PULLDOWN ASSAYS; RESISTANT CELLS; SIGNALING SYSTEMS; SYNTHETIC PEPTIDE; TYROSINE PHOSPHORYLATION;

AMINO ACIDS; BIOACTIVITY; CELL DEATH; INSULIN; ORGANIC ACIDS; PEPTIDES; PHOSPHATASES; PHOSPHORYLATION; SIGNALING;

CLONE CELLS;

CETUXIMAB; FLUORESCEIN ISOTHIOCYANATE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; PROTEIN KINASE C ZETA; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; 3 PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE; 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE; MONOCLONAL ANTIBODY; PEPTIDE FRAGMENT; PROTEIN SERINE THREONINE KINASE;

AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER INHIBITION; CARBOXY TERMINAL SEQUENCE; CELL CLONE; CELL STRAIN MCF 7; COLON ADENOCARCINOMA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; CELL DEATH; CELL SURVIVAL; DRUG RESISTANCE; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN BINDING; SYNTHESIS; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MICE; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION;

EID: 77949904455     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.097410     Document Type: Article

References (61)

1. Samani, A. A., Yakar, S., LeRoith, D., and Brodt, P. (2007) Endocr. Rev. 28, 20-47
2. Samani, A. A., and Brodt, P. (2001) Surg. Oncol. Clin. N. Am. 10, 289-312
3. Ryan, P. D., and Goss, P. E. (2008) Oncologist 13, 16-24
4. LeRoith, D., and Helman, L. (2004) Cancer Cell. 5, 201-202
5. Wu, Y., Cui, K., Miyoshi, K., Hennighausen, L., Green, J. E., Setser, J., LeRoith, D., and Yakar, S. (2003) Cancer Res. 63, 4384-4388
6. Zhang, L., Zhou, W., Velculescu, V. E., Kern, S. E., Hruban, R. H., Hamilton, S. R., Vogelstein, B., and Kinzler, K. W. (1997) Science 276, 1268-1272
7. Ouban, A., Muraca, P., Yeatman, T., and Coppola, D. (2003) Hum. Pathol. 34, 803-808
8. Pollak, M. (2008) Nat. Rev. Cancer 8, 915-928;
9. Correction (2009) Nat. Rev. Cancer. 9, 224
10. Chitnis, M. M., Yuen, J. S., Protheroe, A. S., Pollak, M., and Macaulay, V. M. (2008) Clin. Cancer Res. 14, 6364-6370
11. Mora, A., Komander, D., van Aalten, D. M., and Alessi, D. R. (2004) Semin. Cell. Dev. Biol. 15, 161-170
12. Biondi, R. M., Komander, D., Thomas, C. C., Lizcano, J. M., Deak, M., Alessi, D. R., and van Aalten, D. M. (2002) EMBO J. 21, 4219-4228
13. Biondi, R. M., Cheung, P. C., Casamayor, A., Deak, M., Currie, R. A., and Alessi, D. R. (2000) EMBO J. 19, 979-988
14. Hindie, V., Stroba, A., Zhang, H., Lopez-Garcia, L. A., Idrissova, L., Zeuzem, S., Hirschberg, D., Schaeffer, F., Jørgensen, T. J., Engel, M., Alzari, P. M., and Biondi, R. M. (2009) Nat. Chem. Biol. 5, 758-764
15. Casamayor, A., Morrice, N. A., and Alessi, D. R. (1999) Biochem. J. 342, 287-292
16. Toker, A., and Newton, A. C. (2000) J. Biol. Chem. 275, 8271-8274
17. Wick, M. J., Ramos, F. J., Chen, H., Quon, M. J., Dong, L. Q., and Liu, F. (2003) J. Biol. Chem. 278, 42913-42919
18. Grillo, S., Grémeaux, T., Casamayor, A., Alessi, D. R., Le Marchand-Brustel, Y., and Tanti, J. F. (2000) Eur. J. Biochem. 267, 6642-6649
19. Park, J., Hill, M. M., Hess, D., Brazil, D. P., Hofsteenge, J., and Hemmings, B. A. (2001) J. Biol. Chem. 276, 37459-37471
20. Fiory, F., Alberobello, A. T., Miele, C., Oriente, F., Esposito, I., Corbo, V., Ruvo, M., Tizzano, B., Rasmussen, T. E., Gammeltoft, S., Formisano, P., and Beguinot, F. (2005) Mol. Cell. Biol. 25, 10803-10814
21. Xie, Z., Zeng, X., Waldman, T., and Glazer, R. I. (2003) Cancer Res. 63, 5370-5375
22. Ahmed, N., Riley, C., and Quinn, M. A. (2008) Br. J. Cancer 98, 1415-1424
23. Peifer, C., and Alessi, D. R. (2009) Biochem. J. 417, e5-7
24. Riedemann, J., and Macaulay, V. M. (2006) Endocr. Relat. Cancer 13, S33-43
25. Alessi, D. R., James, S. R., Downes, C. P., Holmes, A. B., Gaffney, P. R., Reese, C. B., and Cohen, P. (1997) Curr. Biol. 7, 261-269
26. Kato, H., Faria, T. N., Stannard, B., Roberts, C. T., Jr., and LeRoith, D. J. (1993) J. Biol. Chem. 268, 2655-2661
27. Ciardiello, F., Bianco, R., Caputo, R., Caputo, R., Damiano, V., Troiani, T., Melisi, D., De Vita, F., De Placido, S., Bianco, A. R., and Tortora, G. (2004) Clin. Cancer Res. 10, 784-793
28. Caruso, M., Miele, C., Formisano, P., Condorelli, G., Bifulco, G., Oliva, A., Auricchio, R., Riccardi, G., Capaldo, B., and Beguinot, F. (1997) J. Biol. Chem. 272, 7290-7297
29. Formisano, P., Oriente, F., Miele, C., Caruso, M., Auricchio, R., Vigliotta, G., Condorelli, G., and Beguinot, F. (1998) J. Biol. Chem. 273, 13197-13202
30. Formisano, P., Sohn, K. J., Miele, C., Di Finizio, B., Petruzziello, A., Riccardi, G., Beguinot, L., and Beguinot, F. (1993) J. Biol. Chem. 268, 5241-5248
31. Fields, G. B., and Noble, R. L. (1990) Int. J. Pept. Protein Res. 35, 161-214
32. Klip, A., Logan, W. J., and Li, G. (1982) Biochim. Biophys. Acta 687, 265-280
33. Jones, H. E., Gee, J. M., Hutcheson, I. R., Knowlden, J. M., Barrow, D., and Nicholson, R. I. (2006) Endocr. Relat. Cancer 13, S45-51
34. Tortora, G., Bianco, R., Daniele, G., Ciardiello, F., McCubrey, J. A., Ricciardi, M. R., Ciuffreda, L., Cognetti, F., Tafuri, A., and Milella, M. (2007) Drug Resist. Updat. 10, 81-100
35. Miller, B. S., and Yee, D. (2005) Cancer Res. 65, 10123-10127
36. Huang, F., Greer, A., Hurlburt, W., Han, X., Hafezi, R., Wittenberg, G. M., Reeves, K., Chen, J., Robinson, D., Li, A., Lee, F. Y., Gottardis, M. M., Clark, E., Helman, L., Attar, R. M., Dongre, A., and Carboni, J. M. (2009) Cancer Res. 69, 161-170
37. Buck, E., Eyzaguirre, A., Rosenfeld-Franklin, M., Thomson, S., Mulvihill, M., Barr, S., Brown, E., O'Connor, M., Yao, Y., Pachter, J., Miglarese, M., Epstein, D., Iwata, K. K., Haley, J. D., Gibson, N. W., and Ji, Q. S. (2008) Cancer Res. 68, 8322-8332
38. Harris, T. K. (2003) IUBMB Life 55, 117-126
39. Komander, D., Fairservice, A., Deak, M., Kular, G. S., Prescott, A. R., Peter Downes, C., Safrany, S. T., Alessi, D. R., and van Aalten, D. M. (2004) EMBO J. 23, 3918-3928
40. Valentinis, B., and Baserga, R. (2001) Mol. Pathol. 54, 133-137
41. Surmacz, E., Sell, C., Swantek, J., Kato, H., Roberts, C. T., Jr., LeRoith, D., and Baserga, R. (1995) Exp. Cell Res. 218, 370-380
42. Reiss, K., Yumet, G., Shan, S., Huang, Z., Alnemri, E., Srinivasula, S. M., Wang, J. Y., Morrione, A., and Baserga, R. (1999) J. Cell. Physiol. 181, 124-135
43. Hongo, A., Yumet, G., Resnicoff, M., Romano, G., O'Connor, R., and Baserga, R. (1998) Cancer Res. 58, 2477-2484
44. Liu, Y., Lehar, S., Corvi, C., Payne, G., and O'Connor, R. (1998) Cancer Res. 58, 570-576
45. Dunn, S. E., Hardman, R. A., Kari, F. W., and Barrett, J. C. (1997) Cancer Res. 57, 2687-2693
46. Wang, Q., and Greene, M. I. (2008) J. Clin. Invest. 118, 2389-2392
47. Guix, M., Faber, A. C., Wang, S. E., Olivares, M. G., Song, Y., Qu, S., Rinehart, C., Seidel, B., Yee, D., Arteaga, C. L., and Engelman, J. A. (2008) J. Clin. Invest. 118, 2609-2619
48. Takahari, D., Yamada, Y., Okita, N. T., Honda, T., Hirashima, Y., Matsubara, J., Takashima, A., Kato, K., Hamaguchi, T., Shirao, K., Shimada, Y., and Shimoda, T. (2009) Oncology 76, 42-48
49. Gallego, R., Codony-Servat, J., García-Albéniz, X., Carcereny, E., Longarón, R., Oliveras, A., Tosca, M., Augé, J. M., Gascón, P., and Maurel, J. (2009) Endocr. Relat. Cancer 16, 311-317
50. Nahta, R., Yuan, L. X., Zhang, B., Kobayashi, R., and Esteva, F. J. (2005) Cancer Res. 65, 11118-11128;
51. Correction (2008) Cancer Res. 68, 9566
52. Barnes, C. J., Ohshiro, K., Rayala, S. K., El-Naggar, A. K., and Kumar, R. (2007) Clin. Cancer Res. 13, 4291-4299
53. Sachdev, D., Singh, R., Fujita-Yamaguchi, Y., and Yee, D. (2006) Cancer Res. 66, 2391-2402
54. Hashimoto, N., Kido, Y., Uchida, T., Asahara, S., Shigeyama, Y., Matsuda, T., Takeda, A., Tsuchihashi, D., Nishizawa, A., Ogawa, W., Fujimoto, Y., Okamura, H., Arden, K. C., Herrera, P. L., Noda, T., and Kasuga, M. (2006) Nat. Genet. 38, 589-593
55. Duronio, V. (2008) Biochem. J. 415, 333-344
56. Seynaeve, C. M., Stetler-Stevenson, M., Sebers, S., Kaur, G., Sausville, E. A., and Worland, P. J. (1993) Cancer Res. 53, 2081-2086
57. Kortmansky, J., Shah, M. A., Kaubisch, A., Weyerbacher, A., Yi, S., Tong, W., Sowers, R., Gonen, M., O'reilly, E., Kemeny, N., Ilson, D. I., Saltz, L. B., Maki, R. G., Kelsen, D. P., and Schwartz, G. K. (2005) J. Clin. Oncol. 23, 1875-1884
58. Jimeno, A., Rudek, M. A., Purcell, T., Laheru, D. A., Messersmith, W. A., Dancey, J., Carducci, M. A., Baker, S. D., Hidalgo, M., and Donehower, R. C. (2008) Cancer Chemother. Pharmacol. 61, 423-433
59. Hu, Y. P., Patil, S. B., Panasiewicz, M., Li, W., Hauser, J., Humphrey, L. E., and Brattain, M. G. (2008) Cancer Res. 68, 8004-8013
60. Sato, S., Fujita, N., and Tsuruo, T. (2004) J. Biol. Chem. 279, 33759-33767
61. Michel, J. J., Townley, I. K., Dodge-Kafka, K. L., Zhang, F., Kapiloff, M. S., and Scott, J. D. (2005) Mol. Cell. 20, 661-672