In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression

Gene Therapy

Volumn 19, Issue 9, 2012, Pages 936-946

  Rahim, A A ^a   Wong, A M ^b   Ahmadi, S ^b   Hoefer, K ^b   Buckley, S M K ^c   Hughes, D A ^c   Nathwani, A N ^c   Baker, A H ^d   McVey, J H ^e   Cooper, J D ^b   Waddington, S N ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

^e THROMBOSIS RESEARCH INSTITUTE   (United Kingdom)

Author keywords

adeno associated virus; adenovirus; fetal brain; gene delivery; pseudotypes

Indexed keywords

ADENOVIRUS VECTOR; GREEN FLUORESCENT PROTEIN; PARVOVIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ADENO ASSOCIATED VIRUS 5; ADENO ASSOCIATED VIRUS 8; ADENO ASSOCIATED VIRUS 9; ADENOVIRUS 5; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DEGENERATIVE DISEASE; FETUS; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; GLIA CELL; IMMUNE RESPONSE; IMMUNOHISTOLOGY; MICROGLIA; MOUSE; NERVE CELL; NEUROLOGIC DISEASE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; WHOLE BODY IMAGING;

ADENOVIRIDAE; ANIMALS; BRAIN; DEPENDOVIRUS; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; MICE; NEUROGLIA; NEURONS; TRANSDUCTION, GENETIC;

ADENO-ASSOCIATED VIRUS; ADENOVIRIDAE; MUS;

EID: 84866123454     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.157     Document Type: Article

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