메뉴 건너뛰기




Volumn 79, Issue 8, 2012, Pages 807-814

Endogenous opioid systems: Current concepts and clinical correlations

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BETA ENDORPHIN; DOPAMINE; DYNORPHIN; ENDOMORPHIN 1; ENKEPHALIN; G PROTEIN COUPLED RECEPTOR; INWARDLY RECTIFYING POTASSIUM CHANNEL; KAPPA OPIATE RECEPTOR; LEVODOPA; MU OPIATE RECEPTOR; NALOXONE; NALTREXONE; NOCICEPTIN; NOCICEPTIN RECEPTOR; OPIATE RECEPTOR; PREPROENKEPHALIN; REMIFENTANIL; RETINA S ANTIGEN; SEROTONIN RECEPTOR; VOLTAGE GATED CALCIUM CHANNEL;

EID: 84866113435     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3182662098     Document Type: Article
Times cited : (115)

References (56)
  • 2
    • 82655187443 scopus 로고    scopus 로고
    • Endogenous opiates and behavior: 2010
    • Bodnar RJ. Endogenous opiates and behavior: 2010. Peptides 2010;32:2522-2552.
    • (2010) Peptides , vol.32 , pp. 2522-2552
    • Bodnar, R.J.1
  • 5
    • 76749102959 scopus 로고    scopus 로고
    • The endogenous opioid system and drug addiction
    • Maldonado R. [The endogenous opioid system and drug addiction.] Ann Pharmaceut Franc 2010;68:3-11.
    • (2010) Ann Pharmaceut Franc , vol.68 , pp. 3-11
    • Maldonado, R.1
  • 6
    • 74049111813 scopus 로고    scopus 로고
    • Delta and kappa opioid receptors as suitable drug targets for pain
    • Vanderah TW. Delta and kappa opioid receptors as suitable drug targets for pain. Clin J Pain 2010;26(suppl 10):S10-S15.
    • (2010) Clin J Pain , vol.26 , Issue.SUPPL. 10
    • Vanderah, T.W.1
  • 11
    • 79955634828 scopus 로고    scopus 로고
    • Extending pharmacological spectrum of opioids beyond analgesia: Multifunctional aspects in different pathophysiological states
    • Sauriyal DS, Jaggi AS, Singh N. Extending pharmacological spectrum of opioids beyond analgesia: multifunctional aspects in different pathophysiological states. Neuropeptides 2011;45:175-188.
    • (2011) Neuropeptides , vol.45 , pp. 175-188
    • Sauriyal, D.S.1    Jaggi, A.S.2    Singh, N.3
  • 12
    • 79960835506 scopus 로고    scopus 로고
    • The role of nociceptin and dynorphin in chronic pain: Implications of neuro-glial interaction
    • Mika J, Obara I, Przewlocka B. The role of nociceptin and dynorphin in chronic pain: implications of neuro-glial interaction. Neuropeptides 2011;45:247-261.
    • (2011) Neuropeptides , vol.45 , pp. 247-261
    • Mika, J.1    Obara, I.2    Przewlocka, B.3
  • 13
    • 33748683820 scopus 로고    scopus 로고
    • Opioids and motor complications in Parkinson's disease
    • Samadi P, Bedard PJ, Rouillard C. Opioids and motor complications in Parkinson's disease. Trends Pharmacol Sci 2006;27:512-517.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 512-517
    • Samadi, P.1    Bedard, P.J.2    Rouillard, C.3
  • 14
    • 80053044761 scopus 로고    scopus 로고
    • Opioidergic interactions between striatal projection neurons
    • Blomeley CP, Bracci E. Opioidergic interactions between striatal projection neurons. J Neurosci 2011;31:13346-13356.
    • (2011) J Neurosci , vol.31 , pp. 13346-13356
    • Blomeley, C.P.1    Bracci, E.2
  • 15
    • 70349801712 scopus 로고    scopus 로고
    • Enkephalins, dynorphins, and beta-endorphin in the rat dorsal horn: An immunofluorescence colocalization study
    • Marvizon JC, Chen W, Murphy N. Enkephalins, dynorphins, and beta-endorphin in the rat dorsal horn: an immunofluorescence colocalization study. J Comp Neurol 2009;517:51-68.
    • (2009) J Comp Neurol , vol.517 , pp. 51-68
    • Marvizon, J.C.1    Chen, W.2    Murphy, N.3
  • 16
    • 33846029187 scopus 로고    scopus 로고
    • Trafficking of delta-opioid receptors and other G-protein-coupled receptors: Implications for pain and analgesia
    • Cahill CM, Holdridge SV, Morinville A. Trafficking of delta-opioid receptors and other G-protein-coupled receptors: implications for pain and analgesia. Trends Pharmacol Sci 2007;28:23-31.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 23-31
    • Cahill, C.M.1    Holdridge, S.V.2    Morinville, A.3
  • 17
    • 72449123327 scopus 로고    scopus 로고
    • Opioid-receptorheteromer-specific trafficking and pharmacology
    • van Rijn RM, Whistler JL, Waldhoer M. Opioid-receptorheteromer-specific trafficking and pharmacology. Curr Opin Pharmacol 2010;10:73-79.
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 73-79
    • Van Rijn, R.M.1    Whistler, J.L.2    Waldhoer, M.3
  • 18
    • 78650551486 scopus 로고    scopus 로고
    • Formation of mu-/kappa-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia
    • Chakrabarti S, Liu NJ, Gintzler AR. Formation of mu-/kappa-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia. Proc Natl Acad Sci USA 2010;107:20115-20119.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 20115-20119
    • Chakrabarti, S.1    Liu, N.J.2    Gintzler, A.R.3
  • 19
    • 2342511488 scopus 로고    scopus 로고
    • Alpha-2-adrenergic and opioid receptor additivity in rat locus coeruleus neurons
    • Stone LS, Wilcox GL. Alpha-2-adrenergic and opioid receptor additivity in rat locus coeruleus neurons. Neurosci Lett 2004;361:265-268.
    • (2004) Neurosci Lett , vol.361 , pp. 265-268
    • Stone, L.S.1    Wilcox, G.L.2
  • 20
    • 70350345550 scopus 로고    scopus 로고
    • Protein kinase C mediates the synergistic interaction between agonists acting at alpha2-adrenergic and delta-opioid receptors in spinal cord
    • Overland AC, Kitto KF, Chabot-Dore AJ, et al. Protein kinase C mediates the synergistic interaction between agonists acting at alpha2-adrenergic and delta-opioid receptors in spinal cord. J Neurosci 2009;29:13264-13273.
    • (2009) J Neurosci , vol.29 , pp. 13264-13273
    • Overland, A.C.1    Kitto, K.F.2    Chabot-Dore, A.J.3
  • 21
    • 77950814617 scopus 로고    scopus 로고
    • Functional interactions between endogenous cannabinoid and opioid systems: Focus on alcohol, genetics and drug-addicted behaviors
    • Lopez-Moreno JA, Lopez-Jimenez A, Gorriti MA, de Fonseca FR. Functional interactions between endogenous cannabinoid and opioid systems: focus on alcohol, genetics and drug-addicted behaviors. Curr Drug Targets 2010;11:406-428.
    • (2010) Curr Drug Targets , vol.11 , pp. 406-428
    • Lopez-Moreno, J.A.1    Lopez-Jimenez, A.2    Gorriti, M.A.3    De Fonseca, F.R.4
  • 23
    • 79955467534 scopus 로고    scopus 로고
    • Distinct pharmacological properties of morphine metabolites at G (i)-protein and beta-arrestin signaling pathways activated by the human mu-opioid receptor
    • Frolich N, Dees C, Paetz C, et al. Distinct pharmacological properties of morphine metabolites at G (i)-protein and beta-arrestin signaling pathways activated by the human mu-opioid receptor. Biochem Pharmacol 2011;81:1248-1254.
    • (2011) Biochem Pharmacol , vol.81 , pp. 1248-1254
    • Frolich, N.1    Dees, C.2    Paetz, C.3
  • 24
    • 78650048600 scopus 로고    scopus 로고
    • Ligand-directed trafficking of the delta-opioid receptor in vivo: Two paths toward analgesic tolerance
    • Pradhan AA, Walwyn W, Nozaki C, et al. Ligand-directed trafficking of the delta-opioid receptor in vivo: two paths toward analgesic tolerance. J Neurosci 2010;30:16459-16468.
    • (2010) J Neurosci , vol.30 , pp. 16459-16468
    • Pradhan, A.A.1    Walwyn, W.2    Nozaki, C.3
  • 25
    • 0017739783 scopus 로고
    • Pain relief by electrical stimulation of the central gray matter in humans and its reversal by naloxone
    • Hosobuchi Y, Adams JE, Linchitz R. Pain relief by electrical stimulation of the central gray matter in humans and its reversal by naloxone. Science 1977;197:183-186.
    • (1977) Science , vol.197 , pp. 183-186
    • Hosobuchi, Y.1    Adams, J.E.2    Linchitz, R.3
  • 26
  • 27
    • 34547442316 scopus 로고    scopus 로고
    • Placebo effects on human mu-opioid activity during pain
    • Wager TD, Scott DJ, Zubieta JK. Placebo effects on human mu-opioid activity during pain. Proc Natl Acad Sci USA 2007;104:11056-11061.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 11056-11061
    • Wager, T.D.1    Scott, D.J.2    Zubieta, J.K.3
  • 28
    • 80052652493 scopus 로고    scopus 로고
    • Placebo analgesia and beyond: A melting pot of concepts and ideas for neuroscience
    • Carlino E, Pollo A, Benedetti F. Placebo analgesia and beyond: a melting pot of concepts and ideas for neuroscience. Curr Opin Anaesthesiol 2011;24:540-544.
    • (2011) Curr Opin Anaesthesiol , vol.24 , pp. 540-544
    • Carlino, E.1    Pollo, A.2    Benedetti, F.3
  • 29
    • 48349135601 scopus 로고    scopus 로고
    • Neural mechanism underlying acupuncture analgesia
    • Zhao ZQ. Neural mechanism underlying acupuncture analgesia. Prog Neurobiol 2008;85:355-375.
    • (2008) Prog Neurobiol , vol.85 , pp. 355-375
    • Zhao, Z.Q.1
  • 30
    • 73649121594 scopus 로고    scopus 로고
    • Activation of mu opioid receptor inhibits the excitatory glutamatergic transmission in the anterior cingulate cortex of the rats with peripheral inflammation
    • Zheng W. Activation of mu opioid receptor inhibits the excitatory glutamatergic transmission in the anterior cingulate cortex of the rats with peripheral inflammation. Eur J Pharmacol 2010;628:91-95.
    • (2010) Eur J Pharmacol , vol.628 , pp. 91-95
    • Zheng, W.1
  • 31
    • 3042789578 scopus 로고    scopus 로고
    • State-dependent opioid control of pain
    • Fields H. State-dependent opioid control of pain. Nat Rev 2004;5:565-575.
    • (2004) Nat Rev , vol.5 , pp. 565-575
    • Fields, H.1
  • 32
    • 84855220752 scopus 로고    scopus 로고
    • Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine
    • Upadhyay J, Anderson J, Baumgartner R, et al. Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine. NeuroImage 2012;59:3762-3773.
    • (2012) NeuroImage , vol.59 , pp. 3762-3773
    • Upadhyay, J.1    Anderson, J.2    Baumgartner, R.3
  • 33
    • 68949162844 scopus 로고    scopus 로고
    • Activation of the opioidergic descending pain control system underlies placebo analgesia
    • Eippert F, Bingel U, Schoell ED, et al. Activation of the opioidergic descending pain control system underlies placebo analgesia. Neuron 2009;63:533-543.
    • (2009) Neuron , vol.63 , pp. 533-543
    • Eippert, F.1    Bingel, U.2    Schoell, E.D.3
  • 34
    • 78651505661 scopus 로고    scopus 로고
    • Neuropharmacological basis of rTMS-induced analgesia: The role of endogenous opioids
    • de Andrade DC, Mhalla A, Adam F, Texeira MJ, Bouhassira D. Neuropharmacological basis of rTMS-induced analgesia: the role of endogenous opioids. Pain 2011;152:320-326.
    • (2011) Pain , vol.152 , pp. 320-326
    • De Andrade, D.C.1    Mhalla, A.2    Adam, F.3    Texeira, M.J.4    Bouhassira, D.5
  • 35
    • 84857930541 scopus 로고    scopus 로고
    • Endogenous endomorphin-2 contributes to spinal k-opioid antinociception
    • Shimoyama M, Toyama S, Tagaito Y, Shimoyama N. Endogenous endomorphin-2 contributes to spinal k-opioid antinociception. Pharmacology 2012;89:145-148.
    • (2012) Pharmacology , vol.89 , pp. 145-148
    • Shimoyama, M.1    Toyama, S.2    Tagaito, Y.3    Shimoyama, N.4
  • 37
    • 81255195541 scopus 로고    scopus 로고
    • Distinct mechanisms underlying pronociceptive effects of opioids
    • Heinl C, Drdla-Schutting R, Xanthos DN, Sandkuhler J. Distinct mechanisms underlying pronociceptive effects of opioids. J Neurosci 2011;31:16748-16756.
    • (2011) J Neurosci , vol.31 , pp. 16748-16756
    • Heinl, C.1    Drdla-Schutting, R.2    Xanthos, D.N.3    Sandkuhler, J.4
  • 38
    • 33244495046 scopus 로고    scopus 로고
    • Kappa opioid control of seizures produced by a virus in an animal model
    • Solbrig MV, Adrian R, Baratta J, Lauterborn JC, Koob GF. Kappa opioid control of seizures produced by a virus in an animal model. Brain 2006;129:642-654.
    • (2006) Brain , vol.129 , pp. 642-654
    • Solbrig, M.V.1    Adrian, R.2    Baratta, J.3    Lauterborn, J.C.4    Koob, G.F.5
  • 39
    • 34249730845 scopus 로고    scopus 로고
    • Endogenous dynorphin in epileptogenesis and epilepsy: Anticonvulsant net effect via kappa opioid receptors
    • Loacker S, Sayyah M, Wittmann W, Herzog H, Schwarzer C. Endogenous dynorphin in epileptogenesis and epilepsy: anticonvulsant net effect via kappa opioid receptors. Brain 2007;130:1017-1028.
    • (2007) Brain , vol.130 , pp. 1017-1028
    • Loacker, S.1    Sayyah, M.2    Wittmann, W.3    Herzog, H.4    Schwarzer, C.5
  • 40
    • 34249715133 scopus 로고    scopus 로고
    • Upregulation of opioid receptor binding following spontaneous epileptic seizures
    • Hammers A, Asselin MC, Hinz R, et al. Upregulation of opioid receptor binding following spontaneous epileptic seizures. Brain 2007;130:1009-1016.
    • (2007) Brain , vol.130 , pp. 1009-1016
    • Hammers, A.1    Asselin, M.C.2    Hinz, R.3
  • 41
    • 84856103876 scopus 로고    scopus 로고
    • Mu opioid receptor mRNA expression, binding, and functional coupling to G-proteins in human epileptic hippocampus
    • Cuellar-Herrera M, Velasco AL, Velasco F, et al. Mu opioid receptor mRNA expression, binding, and functional coupling to G-proteins in human epileptic hippocampus. Hippocampus 2012;22:122-127.
    • (2012) Hippocampus , vol.22 , pp. 122-127
    • Cuellar-Herrera, M.1    Velasco, A.L.2    Velasco, F.3
  • 42
    • 68149182665 scopus 로고    scopus 로고
    • Temporal lobe epilepsy causes selective changes in mu opioid and nociceptin receptor binding and functional coupling to G-proteins in human temporal neocortex
    • Rocha L, Orozco-Suarez S, Alonso-Vanegas M, et al. Temporal lobe epilepsy causes selective changes in mu opioid and nociceptin receptor binding and functional coupling to G-proteins in human temporal neocortex. Neurobiol Dis 2009;35:466-473.
    • (2009) Neurobiol Dis , vol.35 , pp. 466-473
    • Rocha, L.1    Orozco-Suarez, S.2    Alonso-Vanegas, M.3
  • 44
    • 58349101116 scopus 로고    scopus 로고
    • Neuroprotective role of delta-opioid receptors against mitochondrial respiratory chain injury
    • Zhu M, Li MW, Tian XS, Ou XM, Zhu CQ, Guo JC. Neuroprotective role of delta-opioid receptors against mitochondrial respiratory chain injury. Brain Res 2009;1252:183-191.
    • (2009) Brain Res , vol.1252 , pp. 183-191
    • Zhu, M.1    Li, M.W.2    Tian, X.S.3    Ou, X.M.4    Zhu, C.Q.5    Guo, J.C.6
  • 45
    • 80052824632 scopus 로고    scopus 로고
    • Mitochondrial ERK plays a key role in delta-opioid receptor neuroprotection against acute mitochondrial dysfunction
    • Zhu M, Li M, Yang F, et al. Mitochondrial ERK plays a key role in delta-opioid receptor neuroprotection against acute mitochondrial dysfunction. Neurochem Int 2011;59:739-748.
    • (2011) Neurochem Int , vol.59 , pp. 739-748
    • Zhu, M.1    Li, M.2    Yang, F.3
  • 46
    • 34547871256 scopus 로고    scopus 로고
    • Dosedependent neuroprotection of delta opioid peptide [D-Ala2, D-Leu5] enkephalin in neuronal death and retarded behavior induced by forebrain ischemia in rats
    • Su DS, Wang ZH, Zheng YJ, Zhao YH, Wang XR. Dosedependent neuroprotection of delta opioid peptide [D-Ala2, D-Leu5] enkephalin in neuronal death and retarded behavior induced by forebrain ischemia in rats. Neurosci Lett 2007;423:113-117.
    • (2007) Neurosci Lett , vol.423 , pp. 113-117
    • Su, D.S.1    Wang, Z.H.2    Zheng, Y.J.3    Zhao, Y.H.4    Wang, X.R.5
  • 47
    • 84856214188 scopus 로고    scopus 로고
    • Hypoxic preconditioning attenuates global cerebral ischemic injury following asphyxial cardiac arrest through regulation of delta opioid receptor system
    • Gao CJ, Niu L, Ren PC, et al. Hypoxic preconditioning attenuates global cerebral ischemic injury following asphyxial cardiac arrest through regulation of delta opioid receptor system. Neuroscience 2012;202:352-362.
    • (2012) Neuroscience , vol.202 , pp. 352-362
    • Gao, C.J.1    Niu, L.2    Ren, P.C.3
  • 49
    • 80755168028 scopus 로고    scopus 로고
    • Morphine protects against intracellular amyloid toxicity by inducing estradiol release and upregulation of Hsp70
    • Cui J, Wang Y, Dong Q, et al. Morphine protects against intracellular amyloid toxicity by inducing estradiol release and upregulation of Hsp70. J Neurosci 2011;31:16227-16240.
    • (2011) J Neurosci , vol.31 , pp. 16227-16240
    • Cui, J.1    Wang, Y.2    Dong, Q.3
  • 50
    • 81355147501 scopus 로고    scopus 로고
    • Immunomodulatory properties of kappa opioids and synthetic cannabinoids in HIV-1 neuropathogenesis
    • Hu S, Sheng WS, Rock RB. Immunomodulatory properties of kappa opioids and synthetic cannabinoids in HIV-1 neuropathogenesis. J Neuroimmune Pharmacol 2011;6:528-539.
    • (2011) J Neuroimmune Pharmacol , vol.6 , pp. 528-539
    • Hu, S.1    Sheng, W.S.2    Rock, R.B.3
  • 51
    • 77957367692 scopus 로고    scopus 로고
    • Morphine induces the release of CCL5 from astrocytes: Potential neuroprotective mechanism against the HIV protein gp120
    • Avdoshina V, Biggio F, Palchik G, Campbell LA, Mocchetti I. Morphine induces the release of CCL5 from astrocytes: potential neuroprotective mechanism against the HIV protein gp120. Glia 2010;58:1630-1639.
    • (2010) Glia , vol.58 , pp. 1630-1639
    • Avdoshina, V.1    Biggio, F.2    Palchik, G.3    Campbell, L.A.4    Mocchetti, I.5
  • 52
    • 77956184782 scopus 로고    scopus 로고
    • Effects of acute ethanol administration on methionine-enkephalin expression and release in regions of the rat brain
    • Mendez M, Barbosa-Luna IG, Perez-Luna JM, Cupo A, Oikawa J. Effects of acute ethanol administration on methionine-enkephalin expression and release in regions of the rat brain. Neuropeptides 2010;44:413-420.
    • (2010) Neuropeptides , vol.44 , pp. 413-420
    • Mendez, M.1    Barbosa-Luna, I.G.2    Perez-Luna, J.M.3    Cupo, A.4    Oikawa, J.5
  • 53
    • 69249223441 scopus 로고    scopus 로고
    • Role of mu and delta opioid receptors in alcohol drinking behaviour
    • Mendez M, Morales-Mulia M. Role of mu and delta opioid receptors in alcohol drinking behaviour. Curr Drug Abuse Rev 2008;1:239-252.
    • (2008) Curr Drug Abuse Rev , vol.1 , pp. 239-252
    • Mendez, M.1    Morales-Mulia, M.2
  • 54
    • 80053575167 scopus 로고    scopus 로고
    • Opiateinduced dopamine release is modulated by severity of alcohol dependence: An [(18) F]fallypride positron emission tomography study
    • Spreckelmeyer KN, Paulzen M, Raptis M, et al. Opiateinduced dopamine release is modulated by severity of alcohol dependence: an [(18) F]fallypride positron emission tomography study. Biol Psychiatry 2011;70:770-776.
    • (2011) Biol Psychiatry , vol.70 , pp. 770-776
    • Spreckelmeyer, K.N.1    Paulzen, M.2    Raptis, M.3
  • 55
    • 84855656327 scopus 로고    scopus 로고
    • Alcohol consumption induces endogenous opioid release in the human orbitofrontal cortex and nucleus accumbens
    • Mitchell JM, O'Neil JP, Janabi M, Marks SM, Jagust WJ, Fields HL. Alcohol consumption induces endogenous opioid release in the human orbitofrontal cortex and nucleus accumbens. Sci Transl Med 2012;4:116.
    • (2012) Sci Transl Med , vol.4 , pp. 116
    • Mitchell, J.M.1    O'Neil, J.P.2    Janabi, M.3    Marks, S.M.4    Jagust, W.J.5    Fields, H.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.