Catalytic mechanism of the adenylyl and guanylyl cyclases: Modeling and mutational analysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 25, 1997, Pages 13414-13419

  Liu, Yu ^a   Ruoho, Arnold E ^a   Rao, Vibha D ^b   Hurley, James H ^b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE MAGNESIUM; ADENYLATE CYCLASE; ARGININE; ASPARTIC ACID; CYCLIC AMP; CYSTEINE; GLUTAMIC ACID; GUANOSINE PHOSPHATE; GUANYLATE CYCLASE; MAGNESIUM ION; NUCLEOSIDE TRIPHOSPHATASE;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; DICTYOSTELIUM DISCOIDEUM; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SPECIFICITY; HYDROPHOBICITY; MOLECULAR MODEL; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CATALYSIS; DNA PRIMERS; FORSKOLIN; GUANYLATE CYCLASE; KINETICS; METALS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEOTIDES; PROTEIN CONFORMATION; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

DICTYOSTELIUM DISCOIDEUM; MAMMALIA;

EID: 0031473770     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.25.13414     Document Type: Article

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