Identification of a forskolin-like molecule in human renal cysts

Journal of the American Society of Nephrology

Volumn 18, Issue 3, 2007, Pages 934-943

  Putnam, William C ^a   Swenson, Sarah M ^a   Reif, Gail A ^b   Wallace, Darren P ^b   Helmkamp, George M ^b   Grantham, Jared J ^b  

^a MIDWEST RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE ACTIVATOR; CYCLIC AMP; FORSKOLIN;

ADOLESCENT; ADULT; ARTICLE; AUTOSOMAL DOMINANT DISORDER; AUTOSOMAL RECESSIVE DISORDER; CHLORIDE TRANSPORT; CLINICAL ARTICLE; COLEUS; COLEUS FORSKOHLII; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFANT; KIDNEY POLYCYSTIC DISEASE; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL;

EID: 33947282599     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2006111218     Document Type: Article

References (27)

1. Grantham JJ, Chapman AB, Torres VE: Volume progression in autosomal dominant polycystic kidney disease: The major factor determining clinical outcomes. Clin J Am Soc Nephrol 1: 148-157, 2006
2. Belibi FA, Reif G, Wallace DP, Yamaguchi T, Olsen L, Li H, Helmkamp GM Jr, Grantham JJ: Cyclic AMP promotes growth and secretion in human polycystic kidney epithelial cells. Kidney Int 66: 964-973, 2004
3. Ye M, Grant M, Sharma M, Elzinga L, Swan S, Torres VE, Grantham JJ: Cyst fluid from human autosomal dominant polycystic kidneys promotes cyst formation and expansion by renal epithelial cells in vitro. J Am Soc Nephrol 3: 984-994, 1992
4. Grantham JJ: 1992 Homer Smith Award. Fluid secretion, cellular proliferation, and the pathogenesis of renal epithelial cysts. J Am Soc Nephrol 3: 1841-1857, 1993
5. Grantham JJ, Ye M, Davidow C, Holub B, Sharma M: Evidence for a potent lipid secretagogue in the cyst fluids of patients with autosomal dominant polycystic kidney disease. J Am Soc Nephrol 6: 1242-1249, 1995
6. Grantham JJ, Schreiner GF, Rome L, Grenz L, Joly A: Evidence for inflammatory and secretagogue lipids in cyst fluids from patients with autosomal dominant polycystic kidney disease. Proc Assoc Am Physicians 109: 397-408, 1997
7. Ye M, Grantham JJ: The secretion of fluid by renal cysts from patients with autosomal dominant polycystic kidney disease. N Engl J Med 329: 310-313, 1993
8. Mangoo-Karim R, Uchic ME, Grant M, Shumate WA, Calvet JP, Park CH, Grantham JJ: Renal epithelial fluid secretion and cyst growth: The role of cyclic AMP. FASEB J 3: 2629-2632, 1989
9. Mangoo-Karim R, Uchic M, Lechene C, Grantham JJ: Renal epithelial cyst formation and enlargement in vitro: Dependence on cAMP. Proc Natl Acad Sci U S A 86: 6007-6011, 1989
10. Mangoo-Karim R, Ye M, Wallace DP, Grantham JJ, Sullivan LP: Anion secretion drives fluid secretion by monolayers of cultured human polycystic cells. Am J Physiol 269: F381-F388, 1995
11. Wallace DP, Grantham JJ, Sullivan LP: Chloride and fluid secretion by cultured human polycystic kidney cells. Kidney Int 50: 1327-1336, 1996
12. Grantham JJ, Ye M, Gattone VH 2nd, Sullivan LP: In vitro fluid secretion by epithelium from polycystic kidneys. J Clin Invest 95: 195-202, 1995
13. Sullivan LP, Wallace DP, Grantham JJ: Epithelial transport in polycystic kidney disease. Physiol Rev 78: 1165-1191, 1998
14. Sullivan LP, Wallace DP, Grantham JJ: Chloride and fluid secretion in polycystic kidney disease. J Am Soc Nephrol 9: 903-916, 1998
15. Ward CJ, Hogan MC, Rossetti S, Walker D, Sneddon T, Wang X, Kubly V, Cunningham JM, Bacallao R, Ishibashi M, Milliner DS, Torres VE, Harris PC: The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein. Nat Genet 30: 259-269, 2002
16. Tesmer JJ, Sunahara RK, Gilman AG, Sprang SR: Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha. GTPgammaS. Science 278: 1907-1916, 1997
17. Insel PA, Ostrom RS: Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling. Cell Mol Neurobiol 23: 305-314, 2003
18. Engprasert S, Taura F, Kawamukai M, Shoyama Y: Molecular cloning and functional expression of geranylgeranyl pyrophosphate synthase from Coleus forskohlii Briq. BMC Plant Biol 4: 18, 2004
19. Ericsson J, Runquist M, Thelin A, Andersson M, Chojnacki T, Dallner G: Distribution of prenyltransferases in rat tissues. Evidence for a cytosolic all-trans-geranylgeranyl diphosphate synthase. J Biol Chem 268: 832-838, 1993
20. Kainou T, Kawamura K, Tanaka K, Matsuda H, Kawamukai M: Identification of the GGPS1 genes encoding geranylgeranyl diphosphate syntheses from mouse and human. Biochim Biophys Acta 1437: 333-340, 1999
21. Schneider R, Wray V, Nimtz M, Lehmann WD, Kirch U, Antolovic R, Schoner W: Bovine adrenals contain, in addition to ouabain, a second inhibitor of the sodium pump. J Biol Chem 273: 784-792, 1998
22. Van Alstyne KL, Nelson AV, Vyvyan JR, Cancilla DA: Dopamine functions as an antiherbivore defense in the temperate green alga Ulvaria obscura. Oecologia 148: 304-311, 2006
23. Torres VE: Cyclic AMP, at the hub of the cystic cycle. Kidney Int 66: 1283-1285, 2004
24. Gattone VH 2nd, Maser RL, Tian C, Rosenberg JM, Branden MG: Developmental expression of urine concentration-associated genes and their altered expression in murine infantile-type polycystic kidney disease. Dev Genet 24: 309-318, 1999
25. Gattone VH 2nd, Wang X, Harris PC, Torres VE: Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonist. Nat Med 9: 1323-1326, 2003
26. Torres VE, Wang X, Qian Q, Somlo S, Harris PC, Gattone VH 2nd: Effective treatment of an orthologous model of autosomal dominant polycystic kidney disease. Nat Med 10: 363-364, 2004
27. Nagao S, Nishii K, Katsuyama M, Kurahashi H, Marunouchi T, Takahashi H, Wallace DP: Increased water intake decreases progression of polycystic kidney disease in the PCK rat. J Am Soc Nephrol 17: 2220-2227, 2006