Biochemical and pharmacological characterization of P-site inhibitors on homodimeric guanylyl cyclase domain from natriuretic peptide receptor-A

Biochemical Pharmacology

Volumn 73, Issue 7, 2007, Pages 954-963

  Joubert, Simon ^a   McNicoll, Normand ^a   De Léan, André ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Catalysis; Guanylyl cyclase; Natriuretic peptide; Nucleotide; P site inhibitor; Protein dimer; Purine

Indexed keywords

2' DEOXY 3' GUANOSINE PHOSPHATE; CYCLIC GMP; GUANOSINE PHOSPHATE; GUANOSINE TRIPHOSPHATE; GUANYLATE CYCLASE; GUANYLATE CYCLASE INHIBITOR; HOMODIMER; HORMONE RECEPTOR; MAGNESIUM; NATRIURETIC FACTOR; NATRIURETIC PEPTIDE RECEPTOR A; NITRIC OXIDE; PYROPHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITOR INTERACTION; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION;

AMINO ACID MOTIFS; ANIMALS; ATRIAL NATRIURETIC FACTOR; BINDING SITES; DIMERIZATION; ENZYME INHIBITORS; GUANYLATE CYCLASE; INSECTS; PROTEIN CONFORMATION; RECEPTORS, PEPTIDE;

EID: 33847111062     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.12.008     Document Type: Article

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