-
1
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
PMID:18191218
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132:27-42; PMID:18191218; http://dx.doi.org/10.1016/j.cell.2007.12.018
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
2
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
PMID: 18188003
-
Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008; 4:151-75; PMID: 18188003
-
(2008)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.K.4
Aliev, G.5
Askew, D.S.6
-
3
-
-
75749122303
-
Methods in mammalian autophagy research
-
PMID:20144757
-
Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 2010; 140:313- 26; PMID:20144757; http://dx.doi.org/10.1016/j. cell. 2010.01.028
-
(2010)
Cell
, vol.140
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
4
-
-
50249122545
-
Quantitation of autophagy by luciferase release assay
-
PMID:18641457
-
Ketteler R, Seed B. Quantitation of autophagy by luciferase release assay. Autophagy 2008; 4:801-6; PMID:18641457
-
(2008)
Autophagy
, vol.4
, pp. 801-806
-
-
Ketteler, R.1
Seed, B.2
-
5
-
-
39049092790
-
Getting into the flow
-
PMID:18188002
-
Klionsky DJ. Getting into the flow. Autophagy 2008; 4:139-40; PMID:18188002
-
(2008)
Autophagy
, vol.4
, pp. 139-140
-
-
Klionsky, D.J.1
-
6
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
PMID:11060023
-
Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19:5720-8; PMID:11060023; http://dx.doi.org/10. 1093/emboj/19.21.5720
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
-
7
-
-
4344624322
-
LC3 conjugation system in mammalian autophagy
-
PMID:15325588
-
Tanida I, Ueno T, Kominami E. LC3 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 2004; 36:2503-18; PMID:15325588; http://dx. doi.org/10.1016/j.biocel.2004.05.009
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2503-2518
-
-
Tanida, I.1
Ueno, T.2
Kominami, E.3
-
8
-
-
35848967804
-
How to interpret LC3 immunoblotting
-
PMID: 17611390
-
Mizushima N, Yoshimori T. How to interpret LC3 immunoblotting. Autophagy 2007; 3:542-5; PMID: 17611390
-
(2007)
Autophagy
, vol.3
, pp. 542-545
-
-
Mizushima, N.1
Yoshimori, T.2
-
9
-
-
77952766891
-
Autophagy: Assays and artifacts
-
PMID: 20225337
-
Barth S, Glick D, Macleod KF. Autophagy: assays and artifacts. J Pathol 2010; 221:117-24; PMID: 20225337; http://dx.doi.org/10.1002/path.2694
-
(2010)
J Pathol
, vol.221
, pp. 117-124
-
-
Barth, S.1
Glick, D.2
Macleod, K.F.3
-
10
-
-
4644362024
-
In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy
-
PMID:15277523
-
Ichimura Y, Imamura Y, Emoto K, Umeda M, Noda T, Ohsumi Y. In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy. J Biol Chem 2004; 279:40584-92; PMID:15277523; http://dx.doi. org/10.1074/jbc.M405860200
-
(2004)
J Biol Chem
, vol.279
, pp. 40584-40592
-
-
Ichimura, Y.1
Imamura, Y.2
Emoto, K.3
Umeda, M.4
Noda, T.5
Ohsumi, Y.6
-
11
-
-
84859422467
-
Effects of Lipofectamine 2000/siRNA Complexes on Autophagy in Hepatoma Cells
-
PMID:21660602
-
Mo RH, Zaro JL, Ou JH, Shen WC. Effects of Lipofectamine 2000/siRNA Complexes on Autophagy in Hepatoma Cells. Mol Biotechnol 2012; 51:1-8; PMID:21660602; http://dx.doi.org/10.1007/s12033- 011-9422-6
-
(2012)
Mol Biotechnol
, vol.51
, pp. 1-8
-
-
Mo, R.H.1
Zaro, J.L.2
Ou, J.H.3
Shen, W.C.4
-
12
-
-
34250900953
-
LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: Caution in the interpretation of LC3 localization
-
PMID:17387262
-
Kuma A, Matsui M, Mizushima N. LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization. Autophagy 2007; 3:323-8; PMID:17387262
-
(2007)
Autophagy
, vol.3
, pp. 323-328
-
-
Kuma, A.1
Matsui, M.2
Mizushima, N.3
-
13
-
-
35848949567
-
Non-autophagic GFPLC3 puncta induced by saponin and other detergents
-
PMID:17786021
-
Ciechomska IA, Tolkovsky AM. Non-autophagic GFPLC3 puncta induced by saponin and other detergents. Autophagy 2007; 3:586-90; PMID:17786021
-
(2007)
Autophagy
, vol.3
, pp. 586-590
-
-
Ciechomska, I.A.1
Tolkovsky, A.M.2
-
14
-
-
58149089315
-
Autophagy-independent incorporation of GFP-LC3 into protein aggregates is dependent on its interaction with p62/SQSTM1
-
PMID:18776740
-
Shvets E, Elazar Z. Autophagy-independent incorporation of GFP-LC3 into protein aggregates is dependent on its interaction with p62/SQSTM1. Autophagy 2008; 4:1054-6; PMID:18776740
-
(2008)
Autophagy
, vol.4
, pp. 1054-1056
-
-
Shvets, E.1
Elazar, Z.2
-
15
-
-
36148954308
-
High-throughput cellular assays for regulated posttranslational modifications
-
PMID:17961489
-
Robers MB, Horton RA, Bercher MR, Vogel KW, Machleidt T. High-throughput cellular assays for regulated posttranslational modifications. Anal Biochem 2008; 372:189-97; PMID:17961489; http://dx.doi.org/10.1016/j.ab.2007.09.012
-
(2008)
Anal Biochem
, vol.372
, pp. 189-197
-
-
Robers, M.B.1
Horton, R.A.2
Bercher, M.R.3
Vogel, K.W.4
Machleidt, T.5
-
16
-
-
78650081320
-
Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen1 technology
-
PMID:20931131
-
Robers MB, Loh C, Carlson CB, Yang H, Frey EA, Hermanson SB, et al. Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen1 technology. Mol Biosyst 2011; 7: 59-66; PMID:20931131; http://dx.doi.org/10.1039/ c0mb00026d
-
(2011)
Mol Biosyst
, vol.7
, pp. 59-66
-
-
Robers, M.B.1
Loh, C.2
Carlson, C.B.3
Yang, H.4
Frey, E.A.5
Hermanson, S.B.6
-
17
-
-
83455218654
-
TR-FRET cellular assays for interrogating posttranslational modifications of histone H3
-
PMID:21972037
-
Machleidt T, Robers MB, Hermanson SB, Dudek JM, Bi K. TR-FRET cellular assays for interrogating posttranslational modifications of histone H3. J Biomol Screen 2011; 16:1236-46; PMID:21972037; http://dx.doi.org/10.1177/ 1087057111422943
-
(2011)
J Biomol Screen
, vol.16
, pp. 1236-1246
-
-
Machleidt, T.1
Robers, M.B.2
Hermanson, S.B.3
Dudek, J.M.4
Bi, K.5
-
18
-
-
61849179320
-
Development of LanthaScreen cellular assays for key components within the PI3K/AKT/mTOR pathway
-
PMID:19196698
-
Carlson CB, Robers MB, Vogel KW, Machleidt T. Development of LanthaScreen cellular assays for key components within the PI3K/AKT/mTOR pathway. J Biomol Screen 2009; 14:121-32; PMID:19196698; http://dx.doi.org/10.1177/ 1087057108328132
-
(2009)
J Biomol Screen
, vol.14
, pp. 121-132
-
-
Carlson, C.B.1
Robers, M.B.2
Vogel, K.W.3
Machleidt, T.4
-
19
-
-
77954237882
-
Network organization of the human autophagy system
-
PMID:20562859
-
Behrends C, Sowa ME, Gygi SP, Harper JW. Network organization of the human autophagy system. Nature 2010; 466:68-76; PMID:20562859; http://dx.doi.org/ 10.1038/nature09204
-
(2010)
Nature
, vol.466
, pp. 68-76
-
-
Behrends, C.1
Sowa, M.E.2
Gygi, S.P.3
Harper, J.W.4
-
20
-
-
77953661678
-
Baculovirus gene delivery: A flexible assay development tool
-
PMID:20392201
-
Kost TA, Condreay JP, Ames RS. Baculovirus gene delivery: a flexible assay development tool. Curr Gene Ther 2010; 10:168-73; PMID:20392201; http://dx. doi.org/10.2174/156652310791321224
-
(2010)
Curr Gene Ther
, vol.10
, pp. 168-173
-
-
Kost, T.A.1
Condreay, J.P.2
Ames, R.S.3
-
21
-
-
79959800634
-
BacMam-mediated gene delivery into multipotent mesenchymal stromal cells
-
PMID: 21431539
-
O'Grady M, Batchelor RH, Scheyhing K, Kemp CW, Hanson GT, Lakshmipathy U. BacMam-mediated gene delivery into multipotent mesenchymal stromal cells. Methods Mol Biol 2011; 698:485-504; PMID: 21431539; http://dx.doi.org/10.1007/ 978-1-60761- 999-4-34
-
(2011)
Methods Mol Biol
, vol.698
, pp. 485-504
-
-
O'Grady, M.1
Batchelor, R.H.2
Scheyhing, K.3
Kemp, C.W.4
Hanson, G.T.5
Lakshmipathy, U.6
-
22
-
-
9144224360
-
Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes
-
PMID:15355958
-
Tanida I, Ueno T, Kominami E. Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes. J Biol Chem 2004; 279:47704-10; PMID:15355958; http://dx.doi.org/ 10.1074/jbc.M407016200
-
(2004)
J Biol Chem
, vol.279
, pp. 47704-47710
-
-
Tanida, I.1
Ueno, T.2
Kominami, E.3
-
23
-
-
8044257699
-
The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
-
PMID:9030745
-
Blommaart EF, Krause U, Schellens JP, Vreeling- Sindelárová H, Meijer AJ. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. Eur J Biochem 1997; 243:240-6; PMID:9030745; http://dx.doi.org/ 10.1111/j.1432-1033.1997.0240a.x
-
(1997)
Eur J Biochem
, vol.243
, pp. 240-246
-
-
Blommaart, E.F.1
Krause, U.2
Schellens, J.P.3
Vreeling- Sindelá rová, H.4
Meijer, A.J.5
-
24
-
-
0033978633
-
Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
-
PMID:10625637
-
Petiot A, Ogier-Denis E, Blommaart EF, Meijer AJ, Codogno P. Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J Biol Chem 2000; 275:992-8; PMID:10625637; http://dx.doi.org/ 10.1074/jbc.275.2.992
-
(2000)
J Biol Chem
, vol.275
, pp. 992-998
-
-
Petiot, A.1
Ogier-Denis, E.2
Blommaart, E.F.3
Meijer, A.J.4
Codogno, P.5
-
25
-
-
0029741890
-
Active cell death induced by the antiestrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: The role of autophagy
-
PMID:8761415
-
Bursch W, Ellinger A, Kienzl H, Török L, Pandey S, Sikorska M, et al. Active cell death induced by the antiestrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. Carcinogenesis 1996; 17:1595-607; PMID:8761415; http://dx.doi.org/10.1093/ carcin/17. 8.1595
-
(1996)
Carcinogenesis
, vol.17
, pp. 1595-1607
-
-
Bursch, W.1
Ellinger, A.2
Kienzl, H.3
Török, L.4
Pandey, S.5
Sikorska, M.6
-
26
-
-
2442485884
-
Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1
-
PMID:14970205
-
Scarlatti F, Bauvy C, Ventruti A, Sala G, Cluzeaud F, Vandewalle A, et al. Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1. J Biol Chem 2004; 279:18384-91; PMID:14970205; http://dx.doi.org/ 10.1074/jbc.M313561200
-
(2004)
J Biol Chem
, vol.279
, pp. 18384-18391
-
-
Scarlatti, F.1
Bauvy, C.2
Ventruti, A.3
Sala, G.4
Cluzeaud, F.5
Vandewalle, A.6
-
27
-
-
0033003760
-
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays
-
PMID:10838414
-
Zhang JH, Chung TD, Oldenburg KR. A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J Biomol Screen 1999; 4:67-73; PMID:10838414; http://dx.doi.org/10.1177/ 108705719900400206
-
(1999)
J Biomol Screen
, vol.4
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.R.3
-
28
-
-
66449083078
-
ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
-
PMID:19258318
-
Ganley IG, Lam H, Wang J, Ding X, Chen S, Jiang X. ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem 2009; 284:12297-305; PMID:19258318; http://dx. doi.org/10.1074/jbc.M900573200
-
(2009)
J Biol Chem
, vol.284
, pp. 12297-12305
-
-
Ganley, I.G.1
Lam, H.2
Wang, J.3
Ding, X.4
Chen, S.5
Jiang, X.6
-
29
-
-
65249119430
-
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
-
PMID:19211835
-
Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, et al. Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell 2009; 20:1981- 91; PMID:19211835; http://dx.doi.org/10.1091/mbc. E08-12-1248
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1981-1991
-
-
Hosokawa, N.1
Hara, T.2
Kaizuka, T.3
Kishi, C.4
Takamura, A.5
Miura, Y.6
-
30
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
PMID:19225151
-
Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, et al. ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell 2009; 20:1992-2003; PMID:19225151; http://dx.doi. org/10.1091/mbc.E08-12-1249
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
Kim, Y.M.4
Otto, N.M.5
Cao, J.6
-
31
-
-
79960348203
-
Relieving autophagy and 4EBP1 from rapamycin resistance
-
PMID:21576371
-
Nyfeler B, Bergman P, Triantafellow E, Wilson CJ, Zhu Y, Radetich B, et al. Relieving autophagy and 4EBP1 from rapamycin resistance. Mol Cell Biol 2011; 31:2867-76; PMID:21576371; http://dx.doi.org/10. 1128/MCB.05430-11
-
(2011)
Mol Cell Biol
, vol.31
, pp. 2867-2876
-
-
Nyfeler, B.1
Bergman, P.2
Triantafellow, E.3
Wilson, C.J.4
Zhu, Y.5
Radetich, B.6
-
32
-
-
79955631150
-
Autophagy in the cellular energetic balance
-
PMID:21531332
-
Singh R, Cuervo AM. Autophagy in the cellular energetic balance. Cell Metab 2011; 13:495-504; PMID:21531332; http://dx.doi.org/10.1016/j.cmet. 2011.04.004
-
(2011)
Cell Metab
, vol.13
, pp. 495-504
-
-
Singh, R.1
Cuervo, A.M.2
-
33
-
-
0021042747
-
Effect of carboxylic ionophores on lysosomal protein degradation in rat hepatocytes
-
PMID:6641796
-
Grinde B. Effect of carboxylic ionophores on lysosomal protein degradation in rat hepatocytes. Exp Cell Res 1983; 149:27-35; PMID:6641796; http://dx.doi.org/ 10.1016/0014-4827(83)90377-4
-
(1983)
Exp Cell Res
, vol.149
, pp. 27-35
-
-
Grinde, B.1
-
34
-
-
79551553480
-
Dissecting the dynamic turnover of GFP-LC3 in the autolysosome
-
PMID:21107021
-
Ni HM, Bockus A, Wozniak AL, Jones K, Weinman S, Yin XM, et al. Dissecting the dynamic turnover of GFP-LC3 in the autolysosome. Autophagy 2011; 7:188-204; PMID:21107021; http://dx.doi.org/10. 4161/auto.7.2.14181
-
(2011)
Autophagy
, vol.7
, pp. 188-204
-
-
Ni, H.M.1
Bockus, A.2
Wozniak, A.L.3
Jones, K.4
Weinman, S.5
Yin, X.M.6
-
35
-
-
4344696843
-
The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8
-
PMID:15265004
-
Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F. The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8. Genes Cells 2004; 9:611-8; PMID:15265004; http:// dx.doi.org/10.1111/j.1356-9597.2004.00750.x
-
(2004)
Genes Cells
, vol.9
, pp. 611-618
-
-
Sugawara, K.1
Suzuki, N.N.2
Fujioka, Y.3
Mizushima, N.4
Ohsumi, Y.5
Inagaki, F.6
-
36
-
-
77952111333
-
Protein kinase C inhibits autophagy and phosphorylates LC3
-
PMID:20398630
-
Jiang H, Cheng D, Liu W, Peng J, Feng J. Protein kinase C inhibits autophagy and phosphorylates LC3. Biochem Biophys Res Commun 2010; 395:471-6; PMID:20398630; http://dx.doi.org/10.1016/j.bbrc. 2010.04.030
-
(2010)
Biochem Biophys Res Commun
, vol.395
, pp. 471-476
-
-
Jiang, H.1
Cheng, D.2
Liu, W.3
Peng, J.4
Feng, J.5
-
37
-
-
77955875002
-
Regulation of the autophagy protein LC3 by phosphorylation
-
PMID:20713600
-
Cherra SJ, 3rd, Kulich SM, Uechi G, Balasubramani M, Mountzouris J, Day BW, et al. Regulation of the autophagy protein LC3 by phosphorylation. J Cell Biol 2010; 190:533-9; PMID:20713600; http://dx.doi.org/ 10.1083/jcb.201002108
-
(2010)
J Cell Biol
, vol.190
, pp. 533-539
-
-
Cherra III, S.J.1
Kulich, S.M.2
Uechi, G.3
Balasubramani, M.4
Mountzouris, J.5
Day, B.W.6
-
38
-
-
0037134507
-
Solution structure of human GABA(A) receptor-associated protein GABARAP: Implications for biolgoical funcrion and its regulation
-
PMID: 11875056
-
Stangler T, Mayr LM, Willbold D. Solution structure of human GABA(A) receptor-associated protein GABARAP: implications for biolgoical funcrion and its regulation. J Biol Chem 2002; 277:13363-6; PMID: 11875056; http://dx.doi.org/10.1074/jbc.C200050200
-
(2002)
J Biol Chem
, vol.277
, pp. 13363-13366
-
-
Stangler, T.1
Mayr, L.M.2
Willbold, D.3
-
39
-
-
0036193182
-
Crystal structure of the GABA(A)- Receptor-associated protein, GABARAP
-
PMID:11818336
-
Bavro VN, Sola M, Bracher A, Kneussel M, Betz H, Weissenhorn W. Crystal structure of the GABA(A)- receptor-associated protein, GABARAP. EMBO Rep 2002; 3:183-9; PMID:11818336; http://dx.doi.org/ 10.1093/embo-reports/kvf026
-
(2002)
EMBO Rep
, vol.3
, pp. 183-189
-
-
Bavro, V.N.1
Sola, M.2
Bracher, A.3
Kneussel, M.4
Betz, H.5
Weissenhorn, W.6
-
40
-
-
0037012104
-
Structure of GABARAP in two conformations: Implications for GABA(A) receptor localization and tubulin binding
-
PMID:11779480
-
Coyle JE, Qamar S, Rajashankar KR, Nikolov DB. Structure of GABARAP in two conformations: implications for GABA(A) receptor localization and tubulin binding. Neuron 2002; 33:63-74; PMID:11779480; http://dx.doi.org/10.1016/S0896- 6273(01)00558-X
-
(2002)
Neuron
, vol.33
, pp. 63-74
-
-
Coyle, J.E.1
Qamar, S.2
Rajashankar, K.R.3
Nikolov, D.B.4
-
41
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0037085253
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The X-ray crystal structure and putative ligand-derived peptide binding properties of gamma-aminobutyric acid receptor type A receptor-associated protein
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PMID: 11729197
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Knight D, Harris R, McAlister MS, Phelan JP, Geddes S, Moss SJ, et al. The X-ray crystal structure and putative ligand-derived peptide binding properties of gamma-aminobutyric acid receptor type A receptor-associated protein. J Biol Chem 2002; 277:5556-61; PMID: 11729197; http://dx.doi.org/10. 1074/jbc.M109753200
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(2002)
J Biol Chem
, vol.277
, pp. 5556-5561
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Knight, D.1
Harris, R.2
McAlister, M.S.3
Phelan, J.P.4
Geddes, S.5
Moss, S.J.6
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