Homology Modeling of Dopamine D2 and D3 Receptors: Molecular Dynamics Refinement and Docking Evaluation

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Platania, Chiara Bianca Maria ^a   Salomone, Salvatore ^a   Leggio, Gian Marco ^a   Drago, Filippo ^a   Bucolo, Claudio ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 5,6 DIMETHOXYINDAN; 2 DIPROPYLAMINO 7 HYDROXYTETRALIN; 3,4,4A,10B TETRAHYDRO 4 PROPYL 2H,5H [1]BENZOPYRANO[4,3 B][1,4]OXAZIN 9 OL; 4' ACETYL N [4 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]BUTYL]BIPHENYL 4 CARBOXAMIDE; 7 DIPROPYLAMINO 2,3,5,6,7,8 HEXAHYDRONAPHTHO[2,3 B]FURAN; BROMOCRIPTINE; CABERGOLINE; CIANERGOLINE; CIS 8 HYDROXY 3 (N PROPYL)1,2,3A.4,5,9B HEXAHYDRO 1H BENZ[E]INDOLE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR STIMULATING AGENT; DOPAMINE 3 RECEPTOR; ETICLOPRIDE; G PROTEIN COUPLED RECEPTOR; LERGOTRILE; LIGAND; LISURIDE; N (3 HYDROXYPHENETHYL) N (PHENETHYL)PROPYLAMINE; N [4 [2 (6 CYANO 1,2,3,4 TETRAHYDRO 2 ISOQUINOLINYL)ETHYL]CYCLOHEXYL] 4 QUINOLINECARBOXAMIDE; N6 PROPYL N6 [2 [4 [4 [PYRIDIN 4 YL]PHENYL]PIPERAZIN 1 YL] ETHYL] 4,5,6,7 TETRAHYDROBENZO[D] THIAZOLE 2,6 DIAMINE; NAFADOTRIDE; PERGOLIDE; PRAMIPEXOLE; QUINPIROLE; ROPINIROLE; ROTIGOTINE; TETRALIN DERIVATIVE; TRANS 7 HYDROXY 2 [N PROPYL N[3' IODO 2' PROPENYL]AMINO]TETRALIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZINC 45254546;

ARTICLE; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG DEVELOPMENT; DRUG TARGETING; MEMBRANE; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY;

BINDING SITES; DRUG EVALUATION, PRECLINICAL; HUMANS; LIGANDS; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; SALICYLAMIDES; STRUCTURAL HOMOLOGY, PROTEIN; THERMODYNAMICS; USER-COMPUTER INTERFACE;

EID: 84866078621     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044316     Document Type: Article

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