Antiproliferative effects of lectins from Canavalia ensiformis and Canavalia brasiliensis in human leukemia cell lines

Toxicology in Vitro

Volumn 26, Issue 7, 2012, Pages 1161-1169

  Faheina Martins, Glaucia V ^a   da Silveira, Alethéia Lacerda ^a   Cavalcanti, Bruno C ^b   Ramos, Márcio V ^b   Moraes, Manoel O ^b   Pessoa, Cláudia ^b   Araújo, Demetrius A M ^a  

^a FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^b FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

Apoptosis; ConA; ConBr; Cytotoxicity; Flow cytometry; Leukemic cells

Indexed keywords

ANTILEUKEMIC AGENT; CONCANAVALIN A; CONCANAVALIN BR; DNA FRAGMENT; ETOPOSIDE; PLANT LECTIN; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANAVALIA; CANAVALIA BRASILIENSIS; CANAVALIA ENSIFORMIS; CANCER INHIBITION; CELL CYCLE G1 PHASE; CELL MEMBRANE POTENTIAL; CELL METABOLISM; CELL PROLIFERATION; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; DRUG CYTOTOXICITY; FLUORESCENCE; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; PERIPHERAL LYMPHOCYTE; PROMYELOCYTIC LEUKEMIA; TUMOR CELL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CANAVALIA; CELL PROLIFERATION; CELL SURVIVAL; COMET ASSAY; DNA DAMAGE; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; G1 PHASE CELL CYCLE CHECKPOINTS; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; LEUKEMIA, PROMYELOCYTIC, ACUTE; LEUKEMIA, T-CELL; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTES; PLANT LECTINS;

CANAVALIA BRASILIENSIS; CANAVALIA ENSIFORMIS;

EID: 84866045135     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.06.017     Document Type: Article

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