Synbiotics in trauma: Of proven benefit or a new fad?

Intensive Care Units: Stress, Procedures and Mortality Rates

Volumn , Issue , 2010, Pages 149-157

  Kotzampass, Katerina ^a   Eleftheriadis, Efthymios ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84866037206     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (26)

1. Deitch, EA. Multiple organ failure. Ann Surg, 1992, 216, 117-34.
2. Osborn, TM; Tracy, JK; Dunne, JR; Pasquale, M; Napolitano, LM. Epidemiology of sepsis in patients with traumatic injury. Crit Care Med, 2004, 32, 2234-40.
3. Muckart, DJ; Bhagwanjee, S. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference definitions of the systemic inflammatory response syndrome and allied disorders in relation to critically injured patients. Crit Care Med, 1997, 25, 1789-95.
4. Madsen, K; Cornish, A; Soper, P; et al. Probiotic bacteria enhance murine and human intestinal epithelial barrier function. Gastroenterology, 2001, 121, 580-91.
5. Awad, SS. State-of-the-art therapy for severe sepsis and multisystem organ dysfunction. Am JSurg., 2003, 186, 23S-30S.
6. Alverdy, JC; Laughlin, RS; Wu, L. Influence of the critically ill state on host-pathogen interactions within the intestine: gut-derived sepsis redefined. Crit Care Med, 2003, 31, 598-607.
7. Sullivan, A; Edlund, C; Nord, CE. Effect of antimicrobial agents on the ecological balance of human microflora. Lancet Infect Dis, 2001, 1, 101-114.
8. Bartosch, S; Fite, A; Macfarlane, GT; McMurdo, ET. Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using real-Time PCR and effects of antibiotic treatment on the fecal microbiota. Appl Environ Microbiol, 2004, 70, 3575-3581.
9. Schneider, SM; Le Gall, P; Girard Pipau, E; Piche, T; Pompei, A; Nano, JL; Hebuterne X, Rampal P. Total artificial nutrition is associated with major changes in the fecal flora. Eur J Nutr, 2000, 39, 248-255.
10. O’Hara, AM; Shanahan, F. The gut flora as a forgotten organ. EMBO Rep, 2006, 7, 688-93.
11. Guarner, F; Malagelada, JR. Gut flora in health and disease. Lancet, 2003, 361, 512519.
12. Alberda, C; Gramlich, L; Meddings, J; Field, C; McCargar, L; Kutsogiannis, D; Fedorak, R; Madsen, K. Effects of probiotic therapy in critically ill patients: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2007, 85:816-23.
13. Farthing MJG. Bugs and the gut: an unstable marriage. Best Pract Res Clin Gastroenterol, 2004, 18, 233-239.
14. Kinney, KS; Austin, CE; Morton, DS; et al. Norepinephrine as a growth stimulating factor in bacteria: mechanistic studies. Life Science, 2000, 67, 3075-85.
15. Bengmark, S. Bio-ecological control of perioperative and ITU morbidity. Langenbecks Arch Surg., 2004, 389, 145-54.
16. Bengmark, S. Symbiotics to strengthen gut barrier function and reduce morbidity in critically ill patients. Clin Nutr, 2004, 23, 441-45.
17. Bengmark, S. Synbiotics and the mucosal barrier in critically ill patients. Curr Opin Gastroenterol, 2005, 21, 712-16.
18. Yan, F; Polk, DB. Commensal bacteria in the gut: learning who our friends are. Curr Opin Gastroenterol, 2004, 20, 565-71.
19. Morrow, LE. Probiotics in the intensive care unit. Curr Opin Crit Care., 2009, 15, 1448.
20. Sleator, RD, Hill C. Engineered pharmabiotics with improved therapeutic potential. Hum Vaccin, 2008, 4, 271-4.
21. Falcao, de Arruda, IS; de Aguilar-Nascimento, JE. Benefits of early enteral nutrition with glutamine and probiotics in brain injury patients. Clin Sci [Lond]. 2004, 106, 28792.
22. Kotzampassi, K; Giamarellos-Bourboulis, EJ; Voudouris, A; Kazamias, P; Eleftheriadis, E. Benefits of a synbiotic formula [Synbiotic 2000 Forte] in critically ill trauma patients: early results of a randomized controlled trial. World J Surg, 2006, 30, 1848-55.
23. Spindler-Vesel, A; Bengmark, S; Vovk, I; Cerovic, O; Kompan, L. Synbiotics, prebiotics, or peptide in early enteral nutrition: a randomized study in trauma patients. JPEN J Parenter Enteral Nutr, 2007, 31, 119-26.
24. Giamarellos-Bourboulis, EJ; Bengmark, S; Kanellakopoulou, K; Kotzampassi, K. Pro-and synbiotics to control inflammation and infection in patients with multiple injuries. J Trauma, 2009, 67, 815-21.
25. Koutelidakis, J; Bezirtzoglou, E; Giamarellos-Bourboulis, EJ; Grosomanidis, V; Kotzampassi, K. Impact of Synbiotics in intestinal flora of critically ill patients bearing multiple injuries. Int JAntimicrob Agents, 2010, 36,90-1.
26. de Felippe Júnior, J; da Rocha e Silva Júnior, M; Maciel, FM; Soares Ade, M; Mendes, NF. Infection prevention in patients with severe multiple trauma with the immunomodulator beta 1-3 polyglucose [glucan]. Surg Gynecol Obstet., 1993, 177, 383-8.