Differential effects of distinct central nervous system regions on cell migration and axonal extension of neural precursor transplants

Journal of Neuroscience Research

Volumn 90, Issue 11, 2012, Pages 2065-2073

  Jin, Ying ^a   Sura, Karna ^a   Fischer, Itzhak ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Axonal growth; Cell migration; Corpus callosum; Spinal cord; White matter

Indexed keywords

ALKALINE PHOSPHATASE PLACENTA ISOENZYME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CELL DIFFERENTIATION; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; CORPUS CALLOSUM; FEMALE; GLIA CELL; IMMUNOHISTOCHEMISTRY; NERVE FIBER GROWTH; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; OLIGODENDROGLIA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPORTER GENE; SPINAL CORD; TRANSGENIC RAT; WHITE MATTER;

ANIMALS; AXONS; CELL MOVEMENT; CENTRAL NERVOUS SYSTEM; IMMUNOHISTOCHEMISTRY; NEURAL STEM CELLS; RATS; RATS, INBRED F344; RATS, TRANSGENIC;

EID: 84866034729     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23099     Document Type: Article

References (28)

1. Bonner JF, Blesch A, Neuhuber B, Fischer I. 2010. Promoting directional axon growth from neural progenitors grafted into the injured spinal cord. J Neurosci Res 88: 1182-1192.
2. Bonner JF, Connors TM, Silverman WF, Kowalski DP, Lemay MA, Fischer I. 2011. Grafted neural progenitors integrate and restore synaptic connectivity across the injured spinal cord. J Neurosci 31: 4675-4686.
3. Bretzner F, Plemel JR, Liu J, Richter M, Roskams AJ, Tetzlaff W. 2010. Combination of olfactory ensheathing cells with local versus systemic cAMP treatment after a cervical rubrospinal tract injury. J Neurosci Res 88: 2833-2846.
4. Cao QL, Zhang YP, Howard RM, Walters WM, Tsoulfas P, Whittemore SR. 2001. Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage. Exp Neurol 167: 48-58.
5. Caroni P, Schwab ME. 1988. Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading. J Cell Biol 106: 1281-1288.
6. Enomoto M, Shinomiya K, Okabe S. 2003. Migration and differentiation of neural progenitor cells from two different regions of embryonic central nervous system after transplantation into the intact spinal cord. Eur J Neurosci 17: 1223-1232.
7. Han SS, Kang DY, Mujtaba T, Rao MS, Fischer I. 2002. Grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord. Exp Neurol 177: 360-375.
8. Han SS, Liu Y, Tyler-Polsz C, Rao MS, Fischer I. 2004. Transplantation of glial-restricted precursor cells into the adult spinal cord: survival, glial-specific differentiation, and preferential migration in white matter. Glia 45: 1-16.
9. Hill CE, Moon LD, Wood PM, Bunge MB. 2006. Labeled Schwann cell transplantation: cell loss, host Schwann cell replacement, and strategies to enhance survival. Glia 53: 338-343.
10. Jin Y, Fischer I, Tessler A, Houle JD. 2002. Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury. Exp Neurol 177: 265-275.
11. Jin Y, Neuhuber B, Singh A, Bouyer J, Lepore A, Bonner J, Himes T, Campanelli JT, Fischer I. 2011a. Transplantation of human glial restricted progenitors and derived astrocytes into a contusion model of spinal cord injury. J Neurotrauma 28: 579-594.
12. Jin Y, Zhang C, Ziemba KS, Goldstein GA, Sullivan PG, Smith GM. 2011b. Directing dopaminergic fiber growth along a preformed molecular pathway from embryonic ventral mesencephalon transplants in the rat brain. J Neurosci Res 89: 619-627.
13. Karimi-Abdolrezaee S, Eftekharpour E, Wang J, Schut D, Fehlings MG. 2010. Synergistic effects of transplanted adult neural stem/progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically injured spinal cord. J Neurosci 30: 1657-1676.
14. Lepore AC, Fischer I. 2005. Lineage-restricted neural precursors survive, migrate, and differentiate following transplantation into the injured adult spinal cord. Exp Neurol 194: 230-242.
15. Lepore AC, Han SS, Tyler-Polsz CJ, Cai J, Rao MS, Fischer I. 2004. Differential fate of multipotent and lineage-restricted neural precursors following transplantation into the adult CNS. Neuron Glia Biol 1: 113-126.
16. Lepore AC, Neuhuber B, Connors TM, Han SS, Liu Y, Daniels MP, Rao MS, Fischer I. 2006. Long-term fate of neural precursor cells following transplantation into developing and adult CNS. Neuroscience 142: 287-304.
17. Liu Y, Kim D, Himes BT, Chow SY, Schallert T, Murray M, Tessler A, Fischer I. 1999. Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function. J Neurosci 19: 4370-4387.
18. Lu P, Jones LL, Snyder EY, Tuszynski MH. 2003. Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp Neurol 181: 115-129.
19. Mendes SW, Henkemeyer M, Liebl DJ. 2006. Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci 26: 882-892.
20. Nishikimi M, Oishi K, Tabata H, Torii K, Nakajima K. 2011. Segregation and pathfinding of callosal axons through EphA3 signaling. J Neurosci 31: 16251-16260.
21. Rao MS. 2004. Stem sense: a proposal for the classification of stem cells. Stem Cells Dev 13: 452-455.
22. Ruff CA, Fehlings MG. 2010. Neural stem cells in regenerative medicine: bridging the gap. Panminerva Med 52: 125-147.
23. Shihabuddin LS, Horner PJ, Ray J, Gage FH. 2000. Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus. J Neurosci 20: 8727-8735.
24. Singec I, Jandial R, Crain A, Nikkhah G, Snyder EY. 2007. The leading edge of stem cell therapeutics. Annu Rev Med 58: 313-328.
25. Watson DJ, Walton RM, Magnitsky SG, Bulte JW, Poptani H, Wolfe JH. 2006. Structure-specific patterns of neural stem cell engraftment after transplantation in the adult mouse brain. Hum Gene Ther 17: 693-704.
26. Xu XM, Chen A, Guénard V, Kleitman N, Bunge MB. 1997. Bridging Schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cord. J Neurocytol 26: 1-16.
27. Yang H, Mujtaba T, Venkatraman G, Wu YY, Rao MS, Luskin MB. 2000. Region-specific differentiation of neural tube-derived neuronal restricted progenitor cells after heterotopic transplantation. Proc Natl Acad Sci U S A 97: 13366-13371.
28. Ziemba KS, Chaudhry N, Rabchevsky AG, Jin Y, Smith GM. 2008. Targeting axon growth from neuronal transplants along preformed guidance pathways in the adult CNS. J Neurosci 28: 340-348.