Migration and differentiation of neural progenitor cells from two different regions of embryonic central nervous system after transplantation into the intact spinal cord

European Journal of Neuroscience

Volumn 17, Issue 6, 2003, Pages 1223-1232

  Enomoto, Mitsuhiro ^a   Shinomiya, Kenichi ^a   Okabe, Shigeo ^b,c  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Astrocyte; Hippocampus; Oligodendrocyte; Rat; Recombinant adenovirus

Indexed keywords

FIBROBLAST GROWTH FACTOR 2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL LINEAGE; CELL MIGRATION; CELL SURVIVAL; CELL TYPE; CENTRAL NERVOUS SYSTEM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DONOR; EMBRYO; EMBRYO DEVELOPMENT; HIPPOCAMPUS; IN VITRO STUDY; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SPINAL CORD; STEM CELL; STEM CELL TRANSPLANTATION; WHITE MATTER;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL MOVEMENT; CENTRAL NERVOUS SYSTEM; FIBROBLAST GROWTH FACTOR 2; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 0037362044     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02555.x     Document Type: Article

References (31)

1. Brustle, O., Maskos, U. & McKay, R.D. (1995) Host-guided migration allows targeted introduction of neurons into the embryonic brain. Neuron, 15, 1275-1285.
2. Butt, A.M. & Berry, M. (2000) Oligodendrocytes and the control of myelination in vivo: new insights from the rat anterior medullary velum. J. Neurosci. Res., 59, 477-488.
3. Cao, Q.L., Zhang, Y.P., Howard, R.M., Walters, W.M., Tsoulfas, P. & Whittemore, S.R. (2001) Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage. Exp. Neurol., 167, 48-58.
4. Fawcett, J.W. & Asher, R.A. (1999) The glial scar and central nervous system repair. Brain Res. Bull., 49, 377-391.
5. Franklin, R.J., Bayley, S.A. & Blakemore, W.F. (1996) Transplanted CG4 cells (an oligodendrocyte progenitor cell line) survive, migrate, and contribute to repair of areas of demyelination in X-irradiated and damaged spinal cord but not in normal spinal cord. Exp. Neurol., 137, 263-276.
6. Frisen, J., Johansson, C.B., Torok, C., Risling, M. & Lendahl, U. (1995) Rapid, widespread, and longlasting induction of nestin contributes to the generation of glial scar tissue after CNS injury. J. Cell Biol., 131, 453-464.
7. Gage, F.H., Coates, P.W., Palmer, T.D., Kuhn, H.G., Fisher, L.J., Suhonen, J.O., Peterson, D.A., Suhr, S.T. & Ray, J. (1995) Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc. Natl. Acad. Sci. USA, 92, 11879-11883.
8. Genoud, S., Lappe-Siefke, C., Goebbels, S., Radtke, F., Aguet, M., Scherer, S.S., Suter, U., Nave, K.A. & Mantei, N. (2002) Notch1 control of oligodendrocyte differentiation in the spinal cord. J. Cell Biol., 158, 709-718.
9. Groves, A.K., Barnett, S.C., Franklin, R.J., Crang, A.J., Mayer, M., Blakemore, W.F. & Noble, M. (1993) Repair of demyelinated lesions by transplantation of purified O-2A progenitor cells. Nature, 362, 453-455.
10. Harrington, A.W., Kim, J.Y. & Yoon, S.O. (2002) Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis. J. Neurosci., 22, 156-166.
11. Huber, A.B., Ehrengruber, M.U., Schwab, M.E. & Brosamle, C. (2000) Adenoviral gene transfer to the injured spinal cord of the adult rat. Eur. J. Neurosci., 12, 3437-3442.
12. Iwashita, Y., Crang, A.J. & Blakemore, W.F. (2000) Redistribution of bisbenzimide Hoechst 33342 from transplanted cells to host cells. Neuroreport, 11, 1013-1016.
13. Johe, K.K., Hazel, T.G., Muller, T., Dugich-Djordjevic, M.M. & McKay, R.D. (1996) Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev., 10, 3129-3140.
14. Kalyani, A.J., Piper, D., Mujtaba, T., Lucero, M.T. & Rao, M.S. (1998) Spinal cord neuronal precursors generate multiple neuronal phenotypes in culture. J. Neurosci., 18, 7856-7868.
15. Kanegae, Y., Makimura, M. & Saito, I. (1994) A simple and efficient method for purification of infectious recombinant adenovirus. Jpn. J. Med. Sci. Biol., 147, 157-166.
16. Le Gal La Salle, G., Robert, J.J., Berrard, S., Ridoux, V., Stratford-Perricaudet, L.D., Perricaudet, M. & Mallet, J. (1993) An adenovirus vector for gene transfer into neurons and glia in the brain. Science, 259, 988-990.
17. Matthews, M.A. & Duncan, D. (1971) A quantitative study of morphological changes accompanying the initiation and progress of myelin production in the dorsal funiculus of the rat spinal cord. J. Comp. Neurol., 142, 1-22.
18. Miller, R.H. (1996) Oligodendrocyte origins. Trends Neurosci., 19, 92-96.
19. Miller, R.H., Payne, J., Milner, L., Zhang, H. & Orentas, D.M. (1997) Spinal cord oligodendrocytes develop from a limited number of migratory highly proliferative precursors. J. Neurosci. Res., 50, 157-168.
20. Mitome, M., Low, H.P., van den Pol, A., Nunnari, J.J., Wolf, M.K., Billings-Gagliardi, S. & Schwartz, W.J. (2001) Towards the reconstruction of central nervous system white matter using neural precursor cells. Brain, 124, 2147-2161.
21. Miyake, S., Makimura, M., Kanegae, Y., Harada, S., Sato, Y., Takamori, K., Tokuda, C. & Saito, I. (1996) Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Natl. Acad. Sci. USA., 93, 1320-1324.
22. Niwa, H., Yamamura, K. & Miyazaki, J. (1991) Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene, 108, 193-199.
23. O'Leary, M.T. & Blakemore, W.F. (1997) Oligodendrocyte precursors survive poorly and do not migrate following transplantation into the normal adult central nervous system. J. Neurosci. Res., 48, 159-167.
24. Orentas, D.M. & Miller, R.H. (1996) A novel form of migration of glial precursors. Glia, 16, 27-39.
25. Palmer, T.D., Takahashi, J. & Gage, F.H. (1997) The adult rat hippocampus contains primordial neural stem cells. Mol. Cell. Neurosci., 8, 389-404.
26. Prestoz, L., Relvas, J.B., Hopkins, K., Patel, S., Sowinski, P., Price, J. & ffrenc-Constant, C. (2001) Association between integrin-dependent migration capacity of neural stem cells in vitro and anatomical repair following transplantation. Mol. Cell. Neurosci., 18, 473-484.
27. Sabate, O., Horellou, P., Vigne, E., Colin, P., Perricaudet, M., Buc-Caron, M.H. & Mallet, J. (1995) Transplantation to the rat brain of human neural progenitors that were genetically modified using adenoviruses. Nature Genet., 9, 256-260.
28. Shihabuddin, L.S., Horner, P.J., Ray, J. & Gage, F.H. (2000) Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus. J. Neurosci., 20, 8727-8735.
29. Shihabuddin, L.S., Ray, J. & Gage, F.H. (1997) FGF-2 is sufficient to isolate progenitors found in the adult mammalian spinal cord. Exp. Neurol., 148, 577-586.
30. Warrington, A.E., Barbarese, E. & Pfeiffer, S.E. (1993) Differential myelinogenic capacity of specific developmental stages of the oligodendrocyte lineage upon transplantation into hypomyelinating hosts. J. Neurosci. Res., 34, 1-13.
31. Yang, H., Mujtaba, T., Venkatraman, G., Wu, Y.Y., Rao, M.S. & Luskin, M.B. (2000) Region-specific differentiation of neural tube-derived neuronal restricted progenitor cells after heterotopic transplantation. Proc. Natl. Acad. Sci. USA, 97, 13366-13371.