-
1
-
-
33644878480
-
Hypertrophic response and keloid dia thesis: Two very different forms of scar
-
Burd A, Huang L. Hypertrophic response and keloid diathesis: Two very different forms of scar. Plast Reconstr Surg. 2005;116:150e-157e.
-
(2005)
Plast Reconstr Surg
, vol.116
-
-
Burd, A.1
Huang, L.2
-
2
-
-
0031941396
-
The molecular basis of keloid and hypertrophic scar formation
-
Tuan TL, Nichter LS. The molecular basis of keloid and hypertrophic scar formation. Mol Med Today 1998;4:19-24.
-
(1998)
Mol Med Today
, vol.4
, pp. 19-24
-
-
Tuan, T.L.1
Nichter, L.S.2
-
4
-
-
0031781939
-
Transforming growth factor-beta in thermally injured patients with hypertrophic scars: Effects of interferon alpha-2b
-
discussion 1329-1330
-
Tredget EE, Shankowsky HA, Pannu R, et al. Transforming growth factor-beta in thermally injured patients with hypertrophic scars: Effects of interferon alpha-2b. Plast Reconstr Surg. 1998;102:1317-1328; discussion 1329-1330.
-
(1998)
Plast Reconstr Surg
, vol.102
, pp. 1317-1328
-
-
Tredget, E.E.1
Shankowsky, H.A.2
Pannu, R.3
-
5
-
-
0035165788
-
Abnormal balance between proliferation and apoptotic cell death in fibroblasts derived from keloid lesions
-
Luo S, Benathan M, Raffoul W, Panizzon RG, Egloff DV. Abnormal balance between proliferation and apoptotic cell death in fibroblasts derived from keloid lesions. Plast Reconstr Surg. 2001;107:87-96.
-
(2001)
Plast Reconstr Surg
, vol.107
, pp. 87-96
-
-
Luo, S.1
Benathan, M.2
Raffoul, W.3
Panizzon, R.G.4
Egloff, D.V.5
-
6
-
-
0028871240
-
Effects of various growth factors and histamine on cultured keloid fibroblasts
-
Kikuchi K, Kadono T, Takehara K. Effects of various growth factors and histamine on cultured keloid fibroblasts. Dermatology 1995;190:4-8.
-
(1995)
Dermatology
, vol.190
, pp. 4-8
-
-
Kikuchi, K.1
Kadono, T.2
Takehara, K.3
-
7
-
-
0026787117
-
Keloid fibroblasts are refractory to inhibition of DNA synthesis by phorbol esters: Altered response is accompanied by reduced sensitivity to prostaglandin E2 and altered downregulation of phorbol ester binding sites
-
Myles ME, Russell JD, Trupin JS, Smith JC, Russell SB. Keloid fibroblasts are refractory to inhibition of DNA synthesis by phorbol esters: Altered response is accompanied by reduced sensitivity to prostaglandin E2 and altered downregulation of phorbol ester binding sites. J Biol Chem. 1992;267:9014-9020.
-
(1992)
J Biol Chem
, vol.267
, pp. 9014-9020
-
-
Myles, M.E.1
Russell, J.D.2
Trupin, J.S.3
Smith, J.C.4
Russell, S.B.5
-
8
-
-
0347504490
-
Tretinoin reverses upregulation of matrix metalloproteinase-13 in human keloid-derived fibroblasts
-
Uchida G, Yoshimura K, Kitano Y, Okazaki M, Harri K. Tretinoin reverses upregulation of matrix metalloproteinase-13 in human keloid-derived fibroblasts. Exp Dermatol. 2003; 12(Suppl 2):35-42.
-
(2003)
Exp Dermatol
, vol.12
, Issue.SUPPL. 2
, pp. 35-42
-
-
Uchida, G.1
Yoshimura, K.2
Kitano, Y.3
Okazaki, M.4
Harri, K.5
-
9
-
-
24144481523
-
Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration
-
Fujiwara M, Muragaki Y, Ooshima A. Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration. Br J Dermatol. 2005;153:295-300.
-
(2005)
Br J Dermatol
, vol.153
, pp. 295-300
-
-
Fujiwara, M.1
Muragaki, Y.2
Ooshima, A.3
-
10
-
-
65349143115
-
Promoted activation of matrix metalloproteinase (MMP)-2 in keloid fibroblasts and increased expression of MMP-2 in collagen bundle regions: Implications for mechanisms of keloid progression
-
Imaizumi R, Akasaka Y, Inomata N, et al. Promoted activation of matrix metalloproteinase (MMP)-2 in keloid fibroblasts and increased expression of MMP-2 in collagen bundle regions: Implications for mechanisms of keloid progression. Histopathology 2009;54:722-730.
-
(2009)
Histopathology
, vol.54
, pp. 722-730
-
-
Imaizumi, R.1
Akasaka, Y.2
Inomata, N.3
-
11
-
-
33748091739
-
Relaxin: A pleiotropic hormone and its emerging role for experimental and clinical therapeutics
-
Dschietzig T, Bartsch C, Baumann G, Stangl K. Relaxin: A pleiotropic hormone and its emerging role for experimental and clinical therapeutics. Pharmacol Ther. 2006;112:38-56.
-
(2006)
Pharmacol Ther
, vol.112
, pp. 38-56
-
-
Dschietzig, T.1
Bartsch, C.2
Baumann, G.3
Stangl, K.4
-
12
-
-
34548062188
-
Relaxin: Antifibrotic properties and effects in models of disease
-
Samuel CS. Relaxin: Antifibrotic properties and effects in models of disease. Clin Med Res. 2005;3:241-249.
-
(2005)
Clin Med Res
, vol.3
, pp. 241-249
-
-
Samuel, C.S.1
-
14
-
-
3042610399
-
Relaxin's physiological roles and other diverse actions
-
Sherwood OD. Relaxin's physiological roles and other diverse actions. Endocr Rev. 2004;25:205-234.
-
(2004)
Endocr Rev
, vol.25
, pp. 205-234
-
-
Sherwood, O.D.1
-
15
-
-
0025302162
-
Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts
-
Unemori EN, Amento EP. Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts. J Biol Chem. 1990;265:10681-10685.
-
(1990)
J Biol Chem
, vol.265
, pp. 10681-10685
-
-
Unemori, E.N.1
Amento, E.P.2
-
16
-
-
4344606223
-
Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo
-
Samuel CS, Unemori EN, Mookerjee I, et al. Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo. Endocrinology 2004;145:4125-4133.
-
(2004)
Endocrinology
, vol.145
, pp. 4125-4133
-
-
Samuel, C.S.1
Unemori, E.N.2
Mookerjee, I.3
-
17
-
-
33646522213
-
Relaxin in cardiovascular and renal disease
-
Samuel CS, Hewitson TD. Relaxin in cardiovascular and renal disease. Kidney Int. 2006;69:1498-1502.
-
(2006)
Kidney Int
, vol.69
, pp. 1498-1502
-
-
Samuel, C.S.1
Hewitson, T.D.2
-
18
-
-
24944542890
-
The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway
-
Heeg MH, Koziolek MJ, Vasko R, et al. The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway. Kidney Int. 2005;68:96-109.
-
(2005)
Kidney Int
, vol.68
, pp. 96-109
-
-
Heeg, M.H.1
Koziolek, M.J.2
Vasko, R.3
-
19
-
-
0030453783
-
Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo
-
Unemori EN, Pickford LB, Salles AL, et al. Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo. J Clin Invest. 1996;98:2739-2745.
-
(1996)
J Clin Invest
, vol.98
, pp. 2739-2745
-
-
Unemori, E.N.1
Pickford, L.B.2
Salles, A.L.3
-
20
-
-
48349135926
-
Relaxin family peptide receptors: From orphans to therapeutic targets
-
van der Westhuizen ET, Halls ML, Samuel CS, et al. Relaxin family peptide receptors: From orphans to therapeutic targets. Drug Discov Today 2008;13:640-651.
-
(2008)
Drug Discov Today
, vol.13
, pp. 640-651
-
-
Van Der Westhuizen, E.T.1
Halls, M.L.2
Samuel, C.S.3
-
21
-
-
33750207622
-
Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacy
-
Kim JH, Lee YS, Kim H, Huang JH, Yoon AR, Yun CO. Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacy. J Natl Cancer Inst. 2006;98:1482-1493.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1482-1493
-
-
Kim, J.H.1
Lee, Y.S.2
Kim, H.3
Huang, J.H.4
Yoon, A.R.5
Yun, C.O.6
-
22
-
-
34848847836
-
Gene therapy: The first two decades and the current state-of-the-art
-
Flotte TR. Gene therapy: The first two decades and the current state-of-the-art. J Cell Physiol. 2007;213:301-305.
-
(2007)
J Cell Physiol
, vol.213
, pp. 301-305
-
-
Flotte, T.R.1
-
23
-
-
44849098712
-
Plastic surgical delivery systems for targeted gene therapy
-
Ghali S, Dempsey MP, Jones DM, Grogan RH, Butler PE, Gurtner GC. Plastic surgical delivery systems for targeted gene therapy. Ann Plast Surg. 2008;60:323-332.
-
(2008)
Ann Plast Surg
, vol.60
, pp. 323-332
-
-
Ghali, S.1
Dempsey, M.P.2
Jones, D.M.3
Grogan, R.H.4
Butler, P.E.5
Gurtner, G.C.6
-
24
-
-
0041808932
-
Gene therapy progress and prospects: Adenoviral vectors
-
St George JA. Gene therapy progress and prospects: Adenoviral vectors. Gene Ther. 2003;10:1135-1141.
-
(2003)
Gene Ther
, vol.10
, pp. 1135-1141
-
-
St George, J.A.1
-
25
-
-
33749117374
-
Strategies to enhance transductional efficiency of adenoviral-based gene transfer to primary human fibroblasts and keratinocytes as a platform in dermal wounds
-
Stoff A, Rivera AA, Banerjee NS, et al. Strategies to enhance transductional efficiency of adenoviral-based gene transfer to primary human fibroblasts and keratinocytes as a platform in dermal wounds. Wound Repair Regen. 2006;14:608-617.
-
(2006)
Wound Repair Regen
, vol.14
, pp. 608-617
-
-
Stoff, A.1
Rivera, A.A.2
Banerjee, N.S.3
-
26
-
-
0036708228
-
Evaluation of E1B gene-attenuated replicating adenoviruses for cancer gene therapy
-
Kim J, Cho JY, Kim JH, Jung KC, Yun CO. Evaluation of E1B gene-attenuated replicating adenoviruses for cancer gene therapy. Cancer Gene Ther. 2002;9:725-736.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 725-736
-
-
Kim, J.1
Cho, J.Y.2
Kim, J.H.3
Jung, K.C.4
Yun, C.O.5
-
27
-
-
0029977774
-
Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli
-
Chartier C, Degryse E, Gantzer M, Dieterle A, Pavirani A, Mehtali M. Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli. J Virol. 1996;70:4805-4810.
-
(1996)
J Virol
, vol.70
, pp. 4805-4810
-
-
Chartier, C.1
Degryse, E.2
Gantzer, M.3
Dieterle, A.4
Pavirani, A.5
Mehtali, M.6
-
28
-
-
42249106996
-
Efficacy of recombinant adenovirus-mediated double suicide gene therapy in human keloid fibroblasts
-
Xu B, Liu ZZ, Zhu GY, et al. Efficacy of recombinant adenovirus-mediated double suicide gene therapy in human keloid fibroblasts. Clin Exp Dermatol. 2008;33:322-328.
-
(2008)
Clin Exp Dermatol
, vol.33
, pp. 322-328
-
-
Xu, B.1
Liu, Z.Z.2
Zhu, G.Y.3
-
29
-
-
0035096195
-
Relaxin decreases renal interstitial fibrosis and slows progression of renal disease
-
Garber SL, Mirochnik Y, Brecklin CS, et al. Relaxin decreases renal interstitial fibrosis and slows progression of renal disease. Kidney Int. 2001;59:876-882.
-
(2001)
Kidney Int
, vol.59
, pp. 876-882
-
-
Garber, S.L.1
Mirochnik, Y.2
Brecklin, C.S.3
-
30
-
-
36549032746
-
Adenovirusmediated delivery of relaxin reverses cardiac fibrosis
-
Bathgate RA, Lekgabe ED, McGuane JT, et al. Adenovirusmediated delivery of relaxin reverses cardiac fibrosis. Mol Cell Endocrinol. 2008;280:30-38.
-
(2008)
Mol Cell Endocrinol
, vol.280
, pp. 30-38
-
-
Bathgate, R.A.1
Lekgabe, E.D.2
McGuane, J.T.3
-
31
-
-
65349122390
-
Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2
-
Mookerjee I, Hewitson TD, Halls ML, et al. Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2. FASEB J. 2009;23:1219-1229.
-
(2009)
FASEB J
, vol.23
, pp. 1219-1229
-
-
Mookerjee, I.1
Hewitson, T.D.2
Halls, M.L.3
-
32
-
-
35348843493
-
Inhibition of Smad3 expression decreases collagen synthesis in keloid disease fibroblasts
-
Wang Z, Gao Z, Shi Y, et al. Inhibition of Smad3 expression decreases collagen synthesis in keloid disease fibroblasts. J Plast Reconstr Aesthet Surg. 2007;60:1193-1199.
-
(2007)
J Plast Reconstr Aesthet Surg
, vol.60
, pp. 1193-1199
-
-
Wang, Z.1
Gao, Z.2
Shi, Y.3
-
33
-
-
26044450033
-
Smad3 signalling plays an important role in keloid pathogenesis via epithelial-mesenchymal interactions
-
Phan TT, Lim IJ, Aalami O, et al. Smad3 signalling plays an important role in keloid pathogenesis via epithelial-mesenchymal interactions. J Pathol. 2005;207:232-242.
-
(2005)
J Pathol
, vol.207
, pp. 232-242
-
-
Phan, T.T.1
Lim, I.J.2
Aalami, O.3
-
34
-
-
0345304436
-
Quercetin inhibits fibronectin production by keloid-derived fibroblasts: Implication for the treatment of excessive scars
-
Phan TT, Lim IJ, Sun L, et al. Quercetin inhibits fibronectin production by keloid-derived fibroblasts: Implication for the treatment of excessive scars. J Dermatol Sci. 2003;33:192-194.
-
(2003)
J Dermatol Sci
, vol.33
, pp. 192-194
-
-
Phan, T.T.1
Lim, I.J.2
Sun, L.3
-
37
-
-
0033975284
-
Differential expression of matrix metalloproteinases and their tissue-derived inhibitors in cutaneous wound repair
-
Soo C, Shaw WW, Zhang X, Longaker MT, Howard EW, Ting K. Differential expression of matrix metalloproteinases and their tissue-derived inhibitors in cutaneous wound repair. Plast Reconstr Surg. 2000;105:638-647.
-
(2000)
Plast Reconstr Surg
, vol.105
, pp. 638-647
-
-
Soo, C.1
Shaw, W.W.2
Zhang, X.3
Longaker, M.T.4
Howard, E.W.5
Ting, K.6
-
38
-
-
31344447802
-
Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates
-
Newby AC. Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates. Cardiovasc Res. 2006;69:614-624.
-
(2006)
Cardiovasc Res
, vol.69
, pp. 614-624
-
-
Newby, A.C.1
-
39
-
-
0038721960
-
Relaxin increases ubiquitin-dependent degradation of fibronectin in vitro and ameliorates renal fibrosis in vivo
-
McDonald GA, Sarkar P, Rennke H, Unemori E, Kalluri R, Sukhatme VP. Relaxin increases ubiquitin-dependent degradation of fibronectin in vitro and ameliorates renal fibrosis in vivo. Am J Physiol Renal Physiol. 2003;285:F59-F67.
-
(2003)
Am J Physiol Renal Physiol
, vol.285
-
-
McDonald, G.A.1
Sarkar, P.2
Rennke, H.3
Unemori, E.4
Kalluri, R.5
Sukhatme, V.P.6
-
40
-
-
80052216630
-
Adenovirusrelaxin gene therapy for keloids: Implication for reversing pathological fibrosis
-
Lee WJ, Kim YO, Choi IK, Rah DK, Yun CO. Adenovirusrelaxin gene therapy for keloids: Implication for reversing pathological fibrosis. Br J Dermatol. 2011;165:673-677.
-
(2011)
Br J Dermatol
, vol.165
, pp. 673-677
-
-
Lee, W.J.1
Kim, Y.O.2
Choi, I.K.3
Rah, D.K.4
Yun, C.O.5
|