Anxiolytic effects of yokukansan, a traditional Japanese medicine, via serotonin 5-HT1A receptors on anxiety-related behaviors in rats experienced aversive stress

Journal of Ethnopharmacology

Volumn 143, Issue 2, 2012, Pages 533-539

  Yamaguchi, Taku ^a,b   Tsujimatsu, Aki ^a   Kumamoto, Haruko ^a   Izumi, Takeshi ^a   Ohmura, Yu ^a   Yoshida, Takayuki ^a   Yoshioka, Mitsuhiro ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGASAKI INTERNATIONAL UNIVERSITY   (Japan)

Author keywords

Anxiety related behaviors; Anxiolytic effects; Aversive stress; Serotonin 5 HT1A receptors; Yokukansan

Indexed keywords

ANXIOLYTIC AGENT; BUSPIRONE; CORTICOSTERONE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG; YOKUKANSAN;

ANIMAL EXPERIMENT; ANXIETY; ANXIETY DISORDER; ARTICLE; CORTICOSTERONE BLOOD LEVEL; IMMOBILIZATION; LOCOMOTION; MALE; MAZE TEST; NONHUMAN; OPEN FIELD BEHAVIOR; OPEN FIELD TEST; RAT; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; BEHAVIOR, ANIMAL; BUSPIRONE; CORTICOSTERONE; DRUGS, CHINESE HERBAL; FEAR; JAPAN; MALE; MEDICINE, EAST ASIAN TRADITIONAL; MOTOR ACTIVITY; PIPERAZINES; PYRIDINES; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN 5-HT1 RECEPTOR AGONISTS; SEROTONIN 5-HT1 RECEPTOR ANTAGONISTS; STRESS, PHYSIOLOGICAL;

RATTUS;

EID: 84866024762     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.07.007     Document Type: Article

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