Pharmacological studies of geissoschizine methyl ether, isolated from Uncaria sinensis Oliv., in the central nervous system

European Journal of Pharmacology

Volumn 425, Issue 3, 2001, Pages 211-218

  Pengsuparp, Thitima ^a   Indra, Bachtiar ^a   Nakagawasai, Osamu ^b   Tadano, Takeshi ^b   Mimaki, Yoshihiro ^c   Sashida, Yutaka ^c   Ohizumi, Yasushi ^a   Kisara, Kensuke ^b  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

5 HT1A receptor agonist; 5 HT2A 2C receptor antagonist; Geissoschizine methyl ether; Head twitch response; Hypothermic response

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 5 HYDROXYTRYPTOPHAN; CLORGYLINE; ETHER DERIVATIVE; GEISSOSCHIZINE METHYL ETHER; KETANSERIN; MESULERGINE; PLANT EXTRACT; PRAZOSIN; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2C ANTAGONIST; SPIPERONE; TRITIUM; UNCARIA SINENSIS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG ISOLATION; DRUG POTENCY; HEAD TWITCH; LIGAND BINDING; MALE; MEMBRANE BINDING; MOUSE; NONHUMAN; PLANT; PRIORITY JOURNAL; RECTUM TEMPERATURE; SEROTONINERGIC NERVE CELL; UNCARIA SINENSIS;

5-HYDROXYTRYPTOPHAN; 8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BEHAVIOR, ANIMAL; BINDING, COMPETITIVE; BODY TEMPERATURE; BRAIN; CENTRAL NERVOUS SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; DRUGS, CHINESE HERBAL; INDOLES; MALE; MEMBRANES; MICE; MOTOR ACTIVITY; RADIOLIGAND ASSAY; RECTUM; TRITIUM;

EID: 0035902969     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)01195-5     Document Type: Article

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