Mechanism and molecular basis for the sodium channel subtype specificity of μ-conopeptide CnIIIC

British Journal of Pharmacology

Volumn 167, Issue 3, 2012, Pages 576-586

  Markgraf, René ^a   Leipold, Enrico ^a   Schirmeyer, Jana ^a   Paolini Bertrand, Marianne ^b   Hartley, Oliver ^b   Heinemann, Stefan H ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

analgesia; conotoxin; muscle relaxant; patch clamp; sodium channel

Indexed keywords

CONOTOXIN; MU CONOTOXIN CNIIIC; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.4; SODIUM CHANNEL NAV1.5; SODIUM CHANNEL NAV1.8; SODIUM ION; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

AMINO ACID SEQUENCE; ARTICLE; BINDING KINETICS; BINDING SITE; CHANNEL GATING; CONTROLLED STUDY; CONUS SNAIL; DISSOCIATION; DRUG SPECIFICITY; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; MUSCLE RELAXATION; PRIORITY JOURNAL; PROTEIN DOMAIN; SKELETAL MUSCLE;

ANIMALS; BINDING SITES; CONOTOXINS; CONUS SNAIL; HEK293 CELLS; HUMANS; NAV1.4 VOLTAGE-GATED SODIUM CHANNEL; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; SODIUM; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 84866007755     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.02004.x     Document Type: Article

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