메뉴 건너뛰기




Volumn 40, Issue 6, 2012, Pages 874-886

Evidence for the Nitric Oxide Pathway as a Potential Mode of Action in Fenoldopam-induced Vascular Injury

Author keywords

caveolin 1; DIVI; drug induced vascular injury; extracellular superoxide dismutase (ecSOD); nitric oxide; rat; vasodilatation

Indexed keywords

CAVEOLIN 1; CLAUDIN; CONNEXIN 43; FENOLDOPAM; NITRIC OXIDE; PROTEIN ZO1;

EID: 84865984522     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623312444027     Document Type: Article
Times cited : (12)

References (54)
  • 4
    • 0024381695 scopus 로고
    • Ultrastructure of an arterial lesion induced in rats by fenoldopam mesylate, a dopaminergic vasodilator
    • Bugelski P. J. Vockley C. M. Sowinski J. M. Arena E. Berkowitz B. A. Morgan D. G. (1989). Ultrastructure of an arterial lesion induced in rats by fenoldopam mesylate, a dopaminergic vasodilator. Br J Exp Pathol 70, 153–65.
    • (1989) Br J Exp Pathol , vol.70 , pp. 153-165
    • Bugelski, P.J.1    Vockley, C.M.2    Sowinski, J.M.3    Arena, E.4    Berkowitz, B.A.5    Morgan, D.G.6
  • 6
    • 0023739146 scopus 로고
    • Subchronic toxicity of orally-administered (gavage and dosed-feed) theophylline in Fischer 344 rats and B6C3F1 mice
    • Collins J. J. Elwell M. R. Lamb J. C. Manus A. G. Heath J. E. Makovec G. T. (1988). Subchronic toxicity of orally-administered (gavage and dosed-feed) theophylline in Fischer 344 rats and B6C3F1 mice. Fundam Appl Toxicol 11, 472–84.
    • (1988) Fundam Appl Toxicol , vol.11 , pp. 472-484
    • Collins, J.J.1    Elwell, M.R.2    Lamb, J.C.3    Manus, A.G.4    Heath, J.E.5    Makovec, G.T.6
  • 7
    • 33644658285 scopus 로고    scopus 로고
    • Characterization of the inflammatory response to a highly selective PDE4 inhibitor in the rat and the identification of biomarkers that correlate with toxicity
    • Dietsch G. N. DiPalma C. R. Eyre R. J. Pham T. Q. Poole K. M. Pefaur N. B. Welch W. D. Trueblood E. Kerns W. D. Kanaly S. T. (2006). Characterization of the inflammatory response to a highly selective PDE4 inhibitor in the rat and the identification of biomarkers that correlate with toxicity. Toxicol Pathol 34, 39–51.
    • (2006) Toxicol Pathol , vol.34 , pp. 39-51
    • Dietsch, G.N.1    DiPalma, C.R.2    Eyre, R.J.3    Pham, T.Q.4    Poole, K.M.5    Pefaur, N.B.6    Welch, W.D.7    Trueblood, E.8    Kerns, W.D.9    Kanaly, S.T.10
  • 8
    • 0026702944 scopus 로고
    • Cardiotoxicity of vasodilators and positive inotropic/vasodilating drugs in dogs: an overview
    • Dogterom P. Zbinden G. Reznik G. K. (1992). Cardiotoxicity of vasodilators and positive inotropic/vasodilating drugs in dogs: an overview. Crit Rev Toxicol 22, 203–41.
    • (1992) Crit Rev Toxicol , vol.22 , pp. 203-241
    • Dogterom, P.1    Zbinden, G.2    Reznik, G.K.3
  • 10
    • 0035793317 scopus 로고    scopus 로고
    • The caveolar paradox: suppressing, inducing and termination eNOS signaling
    • Feron O. Kelly R. A. (2001). The caveolar paradox: suppressing, inducing and termination eNOS signaling. Circ Res 88, 129–31.
    • (2001) Circ Res , vol.88 , pp. 129-131
    • Feron, O.1    Kelly, R.A.2
  • 11
    • 33646400037 scopus 로고    scopus 로고
    • Role of caveolin-1 in the regulation of the vascular shear stress response
    • Frank P. G. Lisanti M. P. (2006). Role of caveolin-1 in the regulation of the vascular shear stress response. J Clin Invest 116, 1222–5.
    • (2006) J Clin Invest , vol.116 , pp. 1222-1225
    • Frank, P.G.1    Lisanti, M.P.2
  • 12
    • 0036069786 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase and cardiovascular disease
    • Fukai T. Folz R. J. Landmesser U. Harrison D. G. (2002). Extracellular superoxide dismutase and cardiovascular disease. Cardiovasc Res 55, 239–49.
    • (2002) Cardiovasc Res , vol.55 , pp. 239-249
    • Fukai, T.1    Folz, R.J.2    Landmesser, U.3    Harrison, D.G.4
  • 13
    • 0018897859 scopus 로고
    • Effects of short-term and long-term theobromine administration to male dogs
    • Gans J. H. Korson R. Cater M. R. Ackerly C. C. (1980). Effects of short-term and long-term theobromine administration to male dogs. Toxicol Appl Pharmacol 53, 481–96.
    • (1980) Toxicol Appl Pharmacol , vol.53 , pp. 481-496
    • Gans, J.H.1    Korson, R.2    Cater, M.R.3    Ackerly, C.C.4
  • 15
    • 0031708570 scopus 로고    scopus 로고
    • Patterns of drug-induced cardiovascular pathology in the beagle dog: relevance for humans
    • Greaves P. (1998). Patterns of drug-induced cardiovascular pathology in the beagle dog: relevance for humans. Exp Toxicol Pathol 50, 283–93.
    • (1998) Exp Toxicol Pathol , vol.50 , pp. 283-293
    • Greaves, P.1
  • 16
    • 0021719783 scopus 로고
    • Whole body and regional hemodynamic effects of minoxidil in conscious dogs
    • Humphrey S. J. Zins G. R. (1984). Whole body and regional hemodynamic effects of minoxidil in conscious dogs. J Cardiovasc Pharmacol 6, 979–88.
    • (1984) J Cardiovasc Pharmacol , vol.6 , pp. 979-988
    • Humphrey, S.J.1    Zins, G.R.2
  • 17
    • 0019566547 scopus 로고
    • Cardiovascular lesions in Sprague-Dawley rats induced by long-term treatment with caffeine
    • Johansson S. (1981). Cardiovascular lesions in Sprague-Dawley rats induced by long-term treatment with caffeine. Acta Pathol Microbiol Immunol Scand [A] 89, 185–91.
    • (1981) Acta Pathol Microbiol Immunol Scand [A] , vol.89 , pp. 185-191
    • Johansson, S.1
  • 18
    • 17044440916 scopus 로고    scopus 로고
    • Arterial lesions induced by phosphodiesterase III (PDE III) inhibitors and DA(1) agonists
    • Joseph E. C. (2000). Arterial lesions induced by phosphodiesterase III (PDE III) inhibitors and DA(1) agonists. Toxicol Lett 112–113, 537–46.
    • (2000) Toxicol Lett , vol.112-113 , pp. 537-546
    • Joseph, E.C.1
  • 19
    • 0001834782 scopus 로고    scopus 로고
    • Pathogenesis of arterial lesions caused by vasoactive compounds in laboratory animals
    • Bishop, D. P., Kerns, W. E., Pergamon, New York, NY
    • Joseph E. C. Mesfin G. M. Kerns W. D. (1997). Pathogenesis of arterial lesions caused by vasoactive compounds in laboratory animals. In Cardiovascular Toxicology (Bishop D. P. Kerns W. E., eds.), pp. 279–307. Pergamon, New York, NY.
    • (1997) Cardiovascular Toxicology , pp. 279-307
    • Joseph, E.C.1    Mesfin, G.M.2    Kerns, W.D.3
  • 20
    • 0023109883 scopus 로고
    • Heparin-induced release of extracellular superoxide dismutase to human blood plasma
    • Karlsson K. Marklund S. L. (1987). Heparin-induced release of extracellular superoxide dismutase to human blood plasma. Bichochem J 242: 55–9.
    • (1987) Bichochem J , vol.242 , pp. 55-59
    • Karlsson, K.1    Marklund, S.L.2
  • 22
    • 0024431952 scopus 로고
    • Role of dopaminergic and adrenergic receptors in the pathogenesis of arterial lesions induced by fenoldopam mesylate and dopamine in the rat
    • Kerns W. D. Arena E. Morgan D. G. (1989). Role of dopaminergic and adrenergic receptors in the pathogenesis of arterial lesions induced by fenoldopam mesylate and dopamine in the rat. Am J Pathol 135, 339–49.
    • (1989) Am J Pathol , vol.135 , pp. 339-349
    • Kerns, W.D.1    Arena, E.2    Morgan, D.G.3
  • 25
    • 0037058827 scopus 로고    scopus 로고
    • Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: Role of xanthine-oxidase and extracellular superoxide dismutase
    • Landmesser U. Spiekermann S. Dikalov S. Tatge H. Wilke R. Kohler C. Harrison D. G. Hornig B. Drexler H. (2002). Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: Role of xanthine-oxidase and extracellular superoxide dismutase. Circulation 106: 3073–78.
    • (2002) Circulation , vol.106 , pp. 3073-3078
    • Landmesser, U.1    Spiekermann, S.2    Dikalov, S.3    Tatge, H.4    Wilke, R.5    Kohler, C.6    Harrison, D.G.7    Hornig, B.8    Drexler, H.9
  • 26
    • 0030053450 scopus 로고    scopus 로고
    • The toxicity of repeated exposures to rolipram, a type IV phosphodiesterase inhibitor, in rats
    • Larson J. L. Pino M. V. Geiger L. E. Simeone C. R. (1996). The toxicity of repeated exposures to rolipram, a type IV phosphodiesterase inhibitor, in rats. Pharmacol Toxicol 78, 44–9.
    • (1996) Pharmacol Toxicol , vol.78 , pp. 44-49
    • Larson, J.L.1    Pino, M.V.2    Geiger, L.E.3    Simeone, C.R.4
  • 27
    • 0037296811 scopus 로고    scopus 로고
    • Cytotoxicity of nitric oxide donors in smooth muscle cells is dependent on phenotype, and mainly due to apoptosis
    • Lau H. K. (2003). Cytotoxicity of nitric oxide donors in smooth muscle cells is dependent on phenotype, and mainly due to apoptosis. Atherosclerosis 166, 223–32.
    • (2003) Atherosclerosis , vol.166 , pp. 223-232
    • Lau, H.K.1
  • 28
    • 1442324343 scopus 로고    scopus 로고
    • Peroxynitrite induces apoptosis in rat aortic smooth muscle cells: possible relation to vascular diseases
    • Li J. Li W. Su J. Liu W. Altura B. T. Altura B. M. (2004). Peroxynitrite induces apoptosis in rat aortic smooth muscle cells: possible relation to vascular diseases. Exp Biol Med (Maywood) 229, 264–9.
    • (2004) Exp Biol Med (Maywood) , vol.229 , pp. 264-269
    • Li, J.1    Li, W.2    Su, J.3    Liu, W.4    Altura, B.T.5    Altura, B.M.6
  • 29
    • 23044496663 scopus 로고    scopus 로고
    • Dynamic association of nitric oxide downstream signaling molecules with endothelial caveolin-1 in rat aorta
    • Linder A. E. McCluskey L. P. Cole K. R. Lanning K. M. Webb R. C. (2005). Dynamic association of nitric oxide downstream signaling molecules with endothelial caveolin-1 in rat aorta. J Pharmcol Exp Ther 314, 9–15.
    • (2005) J Pharmcol Exp Ther , vol.314 , pp. 9-15
    • Linder, A.E.1    McCluskey, L.P.2    Cole, K.R.3    Lanning, K.M.4    Webb, R.C.5
  • 30
    • 0036830114 scopus 로고    scopus 로고
    • Multiple functions of caveolin-1
    • Liu P. Rudick M. Anderson R. G. (2002). Multiple functions of caveolin-1. J Biol Chem 277, 41295–98.
    • (2002) J Biol Chem , vol.277 , pp. 41295-41298
    • Liu, P.1    Rudick, M.2    Anderson, R.G.3
  • 31
    • 0035165794 scopus 로고    scopus 로고
    • Pathology and pathophysiology of drug-induced arterial injury in laboratory animals and its implications on the evaluation of novel chemical entities for human clinical trials
    • Louden C. Morgan D. G. (2001). Pathology and pathophysiology of drug-induced arterial injury in laboratory animals and its implications on the evaluation of novel chemical entities for human clinical trials. Pharmacol Toxicol 89, 158–70.
    • (2001) Pharmacol Toxicol , vol.89 , pp. 158-170
    • Louden, C.1    Morgan, D.G.2
  • 33
    • 0021218456 scopus 로고
    • Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species
    • Marklund S. L. (1984). Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species. Biochem J 222, 649–55.
    • (1984) Biochem J , vol.222 , pp. 649-655
    • Marklund, S.L.1
  • 34
    • 0035896583 scopus 로고    scopus 로고
    • Isoform-specific localization of voltage-gated K+ channels to distinct lipid raft populations. Targeting of Kv1.5 to caveolae
    • Martens J. R. Sakamoto N. Sullivan S. A. Grobaski T. D. Tamkun M. M. (2001). Isoform-specific localization of voltage-gated K+ channels to distinct lipid raft populations. Targeting of Kv1.5 to caveolae. J Biol Chem 276, 8409–14.
    • (2001) J Biol Chem , vol.276 , pp. 8409-8414
    • Martens, J.R.1    Sakamoto, N.2    Sullivan, S.A.3    Grobaski, T.D.4    Tamkun, M.M.5
  • 36
    • 0033789298 scopus 로고    scopus 로고
    • Evaluation of plasma von willebrand factor as a biomarker for acute arterial damage in rats
    • Newsholme S. J. Thudium D. T. Gossett K. A. Watson E. S. Schwartz L. W. (2000). Evaluation of plasma von willebrand factor as a biomarker for acute arterial damage in rats. Toxicol Pathol 28, 688–93.
    • (2000) Toxicol Pathol , vol.28 , pp. 688-693
    • Newsholme, S.J.1    Thudium, D.T.2    Gossett, K.A.3    Watson, E.S.4    Schwartz, L.W.5
  • 39
    • 0028297231 scopus 로고
    • Internalization of human extracellular superoxide dismutase by bovine aortic endothelial cells
    • Ohata H. Adachi T. Hirano K. (1994). Internalization of human extracellular superoxide dismutase by bovine aortic endothelial cells. Free Rad Biol Med 16, 501–7.
    • (1994) Free Rad Biol Med , vol.16 , pp. 501-507
    • Ohata, H.1    Adachi, T.2    Hirano, K.3
  • 40
    • 0029848789 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase: a regulator of nitric oxide bioavability
    • Oury T. D. Day B. J. Crapo J. D. (1996). Extracellular superoxide dismutase: a regulator of nitric oxide bioavability. Lab Invest 75, 617–36.
    • (1996) Lab Invest , vol.75 , pp. 617-636
    • Oury, T.D.1    Day, B.J.2    Crapo, J.D.3
  • 41
    • 46649119509 scopus 로고    scopus 로고
    • Immunoaffinity liquid chromatography-tandem mass spectrometry detection of nitrotyrosine in biological fluids: Development of a clinically translatable biomarker
    • Radabaugh M. R. Nemirovskiy O. V. Misko T. P. Aggarwal P. Mathews W. R. (2008). Immunoaffinity liquid chromatography-tandem mass spectrometry detection of nitrotyrosine in biological fluids: Development of a clinically translatable biomarker. Analytical Biochem 308, 68–76.
    • (2008) Analytical Biochem , vol.308 , pp. 68-76
    • Radabaugh, M.R.1    Nemirovskiy, O.V.2    Misko, T.P.3    Aggarwal, P.4    Mathews, W.R.5
  • 43
    • 0036406930 scopus 로고    scopus 로고
    • Effect of dexamethasone on the metabonomics profile associated with phosphodiesterase inhibitor-induced vascular lesions in rats
    • Slim R. M. Robertson D. G. Albassam M. Reily M. D. Robosky L. Dethloff L. A. (2002). Effect of dexamethasone on the metabonomics profile associated with phosphodiesterase inhibitor-induced vascular lesions in rats. Toxicol Appl Pharmacol 183, 108–16.
    • (2002) Toxicol Appl Pharmacol , vol.183 , pp. 108-116
    • Slim, R.M.1    Robertson, D.G.2    Albassam, M.3    Reily, M.D.4    Robosky, L.5    Dethloff, L.A.6
  • 44
    • 0242552329 scopus 로고    scopus 로고
    • Apoptosis and nitrative stress associated with phosphodiesterase inhibitor-induced mesenteric vasculitis in rats
    • Slim R. M. Song Y. Albassam M. Dethloff L. A. (2003). Apoptosis and nitrative stress associated with phosphodiesterase inhibitor-induced mesenteric vasculitis in rats. Toxciol Pathol 31, 638–45.
    • (2003) Toxciol Pathol , vol.31 , pp. 638-645
    • Slim, R.M.1    Song, Y.2    Albassam, M.3    Dethloff, L.A.4
  • 45
    • 0028805056 scopus 로고
    • The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase
    • Strälin P. Karlsson K. Johansson B. O. Markland S. L. (1995). The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase. Arterioscler Thom Vasc Biol 15, 2032–6.
    • (1995) Arterioscler Thom Vasc Biol , vol.15 , pp. 2032-2036
    • Strälin, P.1    Karlsson, K.2    Johansson, B.O.3    Markland, S.L.4
  • 46
    • 27744515926 scopus 로고    scopus 로고
    • Functional characterization and expression of endothelin receptors in rat carotid artery: involvement of nitric oxide, a vasodilator prostanoid and the opening of K+ channels in ETB-induced relaxation
    • Tirapelli C. R. Casolari D. A. Yogi A. Montezano A. C. Tostes R. C. Legros E. D’Orleans-Juste P. de Oliveira A. M. (2005). Functional characterization and expression of endothelin receptors in rat carotid artery: involvement of nitric oxide, a vasodilator prostanoid and the opening of K+ channels in ETB-induced relaxation. Br J Pharmacol 146, 903–12.
    • (2005) Br J Pharmacol , vol.146 , pp. 903-912
    • Tirapelli, C.R.1    Casolari, D.A.2    Yogi, A.3    Montezano, A.C.4    Tostes, R.C.5    Legros, E.6    D’Orleans-Juste, P.7    de Oliveira, A.M.8
  • 47
    • 0034063420 scopus 로고    scopus 로고
    • The role of intrarenal nitric oxide in the natriuretic response to dopamine-receptor activation
    • Venkatakrishnan U. Chen C. Lokhandwala M. F. (2000). The role of intrarenal nitric oxide in the natriuretic response to dopamine-receptor activation. Clin Exp Hypertens 22, 309–24.
    • (2000) Clin Exp Hypertens , vol.22 , pp. 309-324
    • Venkatakrishnan, U.1    Chen, C.2    Lokhandwala, M.F.3
  • 48
    • 0021154177 scopus 로고
    • Immediate hemodynamic effects of a dopamine-receptor agonist (fenoldopam) in patients with essential hypertension
    • Ventura H. O. Messerli F. H. Frohlich E. D. Kobrin I. Oigman W. Dunn F. G. Carey R. M. (1984). Immediate hemodynamic effects of a dopamine-receptor agonist (fenoldopam) in patients with essential hypertension. Circulation 69, 1142–45.
    • (1984) Circulation , vol.69 , pp. 1142-1145
    • Ventura, H.O.1    Messerli, F.H.2    Frohlich, E.D.3    Kobrin, I.4    Oigman, W.5    Dunn, F.G.6    Carey, R.M.7
  • 49
    • 0037733050 scopus 로고    scopus 로고
    • Regulated interaction of endothelin B receptor with caveolin-1
    • Yamaguchi T. Murata Y. Fujiyoshi Y. Doi T. (2003). Regulated interaction of endothelin B receptor with caveolin-1. Eur J Biochem 270, 1816–27.
    • (2003) Eur J Biochem , vol.270 , pp. 1816-1827
    • Yamaguchi, T.1    Murata, Y.2    Fujiyoshi, Y.3    Doi, T.4
  • 53
    • 0021907403 scopus 로고
    • Arterial medial necrosis and hemorrhage induced in rats by intravenous infusion of fenoldopam mesylate, a dopaminergic vasodilator
    • Yuhas E. M. Morgan D. G. Arena E. Kupp R. P. Saunders L. Z. Lewis H. B. (1985). Arterial medial necrosis and hemorrhage induced in rats by intravenous infusion of fenoldopam mesylate, a dopaminergic vasodilator. Am J Pathol 119, 83–91.
    • (1985) Am J Pathol , vol.119 , pp. 83-91
    • Yuhas, E.M.1    Morgan, D.G.2    Arena, E.3    Kupp, R.P.4    Saunders, L.Z.5    Lewis, H.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.